Health / Medical Topics

    Immunoglobulin-Mediated Cell Signaling

    A process that involves the binding of an immunoglobulin on the surface of a B cell to a cognate antigen on the surface of a follicular dendritic cell, resulting in a strong survival signal for the immunoglobulin-bearing cell. These interactions are involved in activation, proliferation and maturation of selected B cells and apoptosis of non-selected populations. (NCI Thesaurus)




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