IMREG-1

A low molecular weight fraction of human leukocyte dialysates with potential immunostimulatory activity. IMREG-1 is shown to augment and accelerate human delayed type hypersensitivity (DTH) to recall antigen in vivo, potentiate production of interleukin-2 (IL-2) and interferon gamma, and induce expression of IL-2 receptor in peripheral blood mononuclear cells. These effects are attributed to the peptides Tyr-Gly and Tyr-Gly-Gly, which are identical to the N-terminal end of the enkephalins. Studies in HIV patients have shown that this agent may delay progression to more serious disease and improve laboratory markers. (NCI Thesaurus)

YOU MAY ALSO LIKE

Imputed Time

The time of the observation that is imputed.

Imputed Date

The calendar date of the observation that is imputed.

Impulsive Behavior

Initiation of actions without forethought as to the cost, results or consequences.

Impulse-Control Disorder

A category of psychiatric disorders whose essential features are the failure to resist an impulse to perform an act that is harmful…

Improvement

A condition superior to an earlier condition.

Improve Access

Support the effective dissemination, communication, and utilization of HIV/AIDS information to all constituent communities of the NIH.