Health / Medical Topics

    Inamrinone

    A synthetic bipyridine phosphodiesterase inhibitor with inotropic and vasodilator properties. Inamrinone inhibits type III phosphodiesterase, which is abundant in cardiac and vascular tissues, thereby preventing the degradation of cyclic adenosine monophosphate (cAMP) and increasing intracellular concentrations of this secondary messenger. Elevated levels of cAMP increase the contractile force of the cardiac muscle and produce positive inotropic effects. Although the mechanism of action is not fully understood, inamrinone causes smooth muscle relaxation, resulting in peripheral vasodilation (reduced afterload) and a decreased pulmonary vascular resistance (reduced preload). (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A cancer vaccine made with a form of vaccinia virus that does not cause disease in humans. It is being studied in…
    Issue associated with inadequate or inappropriate storage of the device, not otherwise described.
    Pacing voltage or pulse width is less than desired.
    Issue associated with inadequate periodic preventive maintenance or performance assurance checks.
    Issue associated with the insufficient removal of unwanted visible soil, foreign material or organism deposits on the external surfaces, crevices, joints of…
    Insufficient information on the labels or in the manuals related to a device's instructions for use e.g. steps that are difficult to…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact