Indium In-111 Ibritumomab Tiuxetan

Definition 1

A targeted radioimmunoconjugate composed of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by a chelator (tiuxetan) to the imaging radioisotope indium-111. This radioimmunoconjugate binds to CD20-positive cells, permitting radioimmuno-localization of CD20-positive cell biodistribution. (NCI Thesaurus)

Definition 2

A radiolabeled monoclonal antibody that is used to detect certain types of B-cell non-Hodgkin lymphoma and is being studied in the detection of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope indium 111. It binds to the protein called CD20, which is found on B cells. A machine is used to detect which cells in the body have bound the antibody. In 111 ibritumomab tiuxetan is a type of radiopharmaceutical. (NCI Dictionary)

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