Infantile Fibrosarcoma

Pronunciation

Definition 1

A fibrosarcoma, occurring in infants and young children, sharing identical morphologic features with adult fibrosarcoma. The prognosis is generally much more favorable than for adult fibrosarcoma, and it rarely metastasizes. It usually affects the superficial and deep soft tissues of the extremities. The majority of infantile fibrosarcomas carry the t(12;15)(p13;q26) translocation. (NCI Thesaurus)

Definition 2

A fibrosarcoma that is histologically identical to classical fibrosarcoma of adults, but has a much more favorable prognosis. It occurs in infants and young children, metastasizes rarely and is morphologically and genetically related to congenital mesoblastic nephroma. Most infantile fibrosarcomas have the chromosomal translocation t(12;15)(p13;q26). (NCI Thesaurus)

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