Ingliforib

A glycogen phosphorylase inhibitor with antihyperglycemic and cardioprotective activities. Ingliforib inhibits glycogen phosphorylase, the rate-limiting enzyme in glycogenolysis, thereby preventing the release of glucose-1 phosphate from a glycogen molecule in liver. This agent also inhibits glycogen phosphorylase in cardiac muscle and may protect the heart from myocardial ischemic injury by preserving glycogen content and improving glycolytic-oxidative coupling. (NCI Thesaurus)

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Taking into the body by mouth.

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A selective small-molecule activator of protein kinase C (PKC) isolated from the plant Euphorbia peplus with potential antineoplastic activity. Ingenol mebutate activates…

ING2 wt Allele

Human ING2 wild-type allele is located in the vicinity of 4q35.1 and is approximately 6 kb in length. This allele, which encodes…

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This gene plays a role in the modulation of both protein acetylation and apoptosis.

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Human ING1 wild-type allele is located within 13q34 and is approximately 8 kb in length. This allele, which encodes inhibitor of growth…