| Library / English Dictionary |
INHIBITED
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Held back or restrained or prevented
Example:
in certain conditions previously inhibited conditioned reactions can reappear
Classified under:
Similar:
pent-up; repressed (characterized by or showing the suppression of impulses or emotions)
smothered; stifled; strangled; suppressed (held in check with difficulty)
Also:
reserved (marked by self-restraint and reticence)
restrained (under restraint)
Antonym:
uninhibited (not inhibited or restrained)
II. (verb)
Sense 1
Past simple / past participle of the verb inhibit
Context examples:
Caspase-3 further increases its own activation by proteolytically cleaving ceramide inhibited catalase which is an inhibitor of ROS generation.
(Ceramide Signaling Pathway BioCarta, NCI Thesaurus/BIOCARTA)
As a result, osteoclast activity is inhibited and bone resorption and turnover are reduced.
(Alendronate sodium, NCI Thesaurus)
Subsequently, the function of Hsp90 is inhibited, leading to the degradation and depletion of its client proteins such as kinases and transcription factors involved with cell cycle regulation and signal transduction.
(Alvespimycin, NCI Thesaurus)
The targeted nanoparticles inhibited body weight gain by about 10% compared to untreated mice, or to mice treated with Rosi in solution or in nontargeted nanoparticles.
(Nanoparticles target, transform fat tissue, NIH)
NO stimulates guanylate (G-) cyclase and increases cGMP levels. cGMP activates cGMP-dependent protein kinase (PKG), cGMP-inhibited phosphodiesterase (PDEIII), and cGMP-stimulated phosphodiesterase (PDEII).
(Nitric Oxide Pathway, NCI Thesaurus/BIOCARTA)
Indeed, when there is limited emotional identification with other people, communication becomes inhibited and, ultimately, this may lead to negative—even tragic—results.
(White people’s perceptions of the emotions on black people’s faces are less accurate than their perceptions among other white people, University of Granada)
By preventing this HDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of p53 signaling and, thus, the p53-mediated induction of tumor cell apoptosis.
(p53/HDM2 Interaction Inhibitor CGM097, NCI Thesaurus)
If this process is inhibited, the LDL receptor is protected against degradation, and the amount of cholesterol in the blood falls.
(Discovery Can Pave the Way for More Effective Cholesterol Medicine, The Titi Tudorancea Bulletin)
As a result, herpes viral DNA synthesis and replication are selectively inhibited.
(Penciclovir, NCI Thesaurus)
PLC d1 activity is feedback-inhibited by IP3, which has an 8-fold higher affinity for PLC d1 than does PIP2.
(Phospholipid Associated Cell Signaling Pathway, NCI Thesaurus/BIOCARTA)
