| Health / Medical Topics |
Innate Immunostimulator rBBX-01
A recombinant 19 kDa protein derived from the Apicomplexa protozoan Eimeria with potential immunostimulating and antitumor activities. Upon administration, innate immunostimulator rBBX-01 activates dendritic cells (DCs), stimulates the Toll-like receptor 11 (TLR-11)-mediated release of interleukin-12 (Il-12) from DCs, and induces a T-helper 1 (Th1) type immune response, which may induce an immune response against tumor cells. Infection with Eimeria, a coccidian commonly infecting the intestine, may be negatively correlated with tumorigenesis. (NCI Thesaurus)
YOU MAY ALSO LIKE
A synthetic, 5-amino acid peptide and Innate Defense Regulator (IDR), with immunomodulating, anti-inflammatory, anti-infective and anti-mucositis activities. Upon intravenous administration, SGX942 binds…
Innate Bone Remodeling takes place in the adult skeleton at discrete foci. The continuous turnover of bone matrix and mineral that involves…
A drug used to treat advanced renal cell carcinoma (the most common type of kidney cancer). It is used in patients who…
A valve that controls the flow of fluids in through the wall of a chamber.
A class of disorders that encompasses conditions resulting from an injury, poisoning or procedure.
Damage to the superior vena cava from traumatic or pathologic processes.
