INO-1001

A isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties. INO-1001 inhibits PARP, which may result in inhibition of tumor cell DNA repair mechanisms and, so, tumor cell resistance to chemotherapy and radiation therapy. PARP enzymes are activated by DNA breaks and have been implicated in the repair of DNA single-strand breaks (SSB). (NCI Thesaurus)

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Innominate Artery Branch

One of two arteries (right common carotid and right subclavian) that branch off of the innominate artery.

Innominate Artery

An artery arising from the aortic arch that divides into the right common carotid and right subclavian arteries.

Innohep

A drug that is used with another drug, warfarin, to treat blood clots that form deep in the veins and to prevent…

Inner Wall of the Vestibule

The wall facing the inside of the vestibule of the inner ear.

Inner Wall of the Tympanum

The internal wall of the tympanic cavity.

Inner Supporting Cell

A tall, slender cell extending from the basilar membrane to the free surface of the organ of Corti. Each cell surrounds an…