Library / English Dictionary

INOSITOL

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

An optically inactive alcohol that is a component of the vitamin B complex

Classified under:

Nouns denoting substances

Hypernyms ("inositol" is a kind of...):

B; B-complex vitamin; B complex; B vitamin; vitamin B; vitamin B complex (originally thought to be a single vitamin but now separated into several B vitamins)

Credits

 Context examples: 

Also called inositol hexaphosphate and IP6.

(Phytic acid, NCI Dictionary)

A molecular genetic abnormality indicating the presence of a mutation in the PI3KCA (phosphatidyl inositol 3-kinase) gene on chromosome 3q26.32.

(PI3KCA Gene Mutation, NCI Thesaurus)

This gene plays a role in the synthesis of glycophosphatidyl inositol anchors.

(PIGF Gene, NCI Thesaurus)

A molecular genetic abnormality indicating the presence of multiple copies of the PIK3CA (phosphatidyl inositol 3-kinase) gene.

(PIK3CA Gene Amplification, NCI Thesaurus)

Phospholipase C (PLC) d1 is a member of the PLC family that produces two second messengers, diacylglycerol (DAG) and inositol 1,4,5-triphosphate (IP3) by hydrolyzing the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2).

(Phospholipid Associated Cell Signaling Pathway, NCI Thesaurus/BIOCARTA)

Its main function is to hydrolyze phosphatidylinositol diphosphate into diacylglycerol (DG) and inositol triphosphate (IP3).

(Phospholipase C Signaling Pathway, NCI Thesaurus/BIOCARTA)

This protein plays a role in the first step of inositol-1,4,5,-trisphosphate production.

(Phosphatidylinositol 4-Kinase Beta, NCI Thesaurus)

This protein plays a role in glycophosphatidyl inositol anchor biosynthesis.

(Phosphatidylinositol-Glycan Biosynthesis Class F Protein, NCI Thesaurus)

Nine currently identified phosphoinositide 3-kinases (PI 3-K) constitute a subfamily of lipid kinases that catalyze the addition of a phosphate molecule on the 3-position of the inositol ring of phosphoinositides.

(Phosphoinositide Pathway, NCI Thesaurus/BIOCARTA)

Inositol 1,4,5-trisphosphate acts as an intermediate in the IP3/DAG pathway, hydrolyzed by phospholipase C and liberating diacylglycerol and PIP2, which activate Protein Kinase C and calcium release from the endoplasmic reticulum, respectively.

(Inositol 1,4,5-Trisphosphate, NCI Thesaurus)