INSS Stage 4

The tumor extends across the midline and the regional lymph nodes may or may not be involved by tumor; or the tumor…

The tumor is unilateral and the resection is complete or incomplete; ipsilateral lymph nodes are involved by tumor.

The tumor is unilateral and the resection is grossly incomplete; no evidence of lymph node involvement.

The tumor is confined to the original site of growth; no metastasis.

Human INSRR wild-type allele is located within 1q21-q23 and is approximately 18 kb in length. This allele, which encodes insulin receptor-related protein,…

This gene is thought to play a role in insulin regulation; however, the exact function is not known.