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INSTABILITY
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I. (noun)
Sense 1
Meaning:
The quality or attribute of being unstable and irresolute
Synonyms:
instability; unstableness
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("instability" is a kind of...):
unsteadiness (the quality of being unsteady--varying and unpredictable)
Hyponyms (each of the following is a kind of "instability"):
shakiness (the quality of being unstable and insecure)
Antonym:
stability (the quality or attribute of being firm and steadfast)
Sense 2
Meaning:
Unreliability attributable to being unstable
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("instability" is a kind of...):
undependability; undependableness; unreliability; unreliableness (the trait of not being dependable or reliable)
Sense 3
Meaning:
An unstable order
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("instability" is a kind of...):
disorder (a disturbance of the peace or of public order)
Antonym:
stability (a stable order (especially of society))
Sense 4
Meaning:
A lack of balance or state of disequilibrium
Example:
a hormonal imbalance
Synonyms:
imbalance; instability; unbalance
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("instability" is a kind of...):
disequilibrium (loss of equilibrium attributable to an unstable situation in which some forces outweigh others)
Context examples:
At the molecular level, high-frequency microsatellite instability is present.
(Lynch syndrome, NCI Thesaurus)
Genomic instability associated with defective DNA mismatch repair in tumors.
(Microsatellite instability, NCI Thesaurus)
This enhances the accumulation of DNA strand breaks and promotes genomic instability and eventually leads to apoptosis.
(PARP Inhibitor AZD2461, NCI Thesaurus)
This enhances the accumulation of DNA strand breaks, promotes genomic instability and eventually leads to apoptosis.
(PARP Inhibitor BMN-673, NCI Thesaurus)
This agent enhances the accumulation of DNA strand breaks and promotes genomic instability and apoptosis.
(PARP Inhibitor CEP-9722, NCI Thesaurus)
This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis.
(PARP-1/2 Inhibitor ABT-767, NCI Thesaurus)
This agent enhances the accumulation of single and double strand DNA breaks and promotes genomic instability eventually leading to apoptosis.
(PARP 1/2 Inhibitor E7449, NCI Thesaurus)
Symptoms may develop after minor trauma and include localized neck pain, atlantoaxial instability, and transient or permanent neurologic manifestations.
(Odontoid Hypoplasia, NCI Thesaurus)
A laboratory procedure to detect microsatellite instability.
(Microsatellite Instability Analysis, NCI Thesaurus)
Changes in the length of the repeat indicate mutations in mismatch repair genes resulting in microsatellite instability.
(Mononucleotide and Dinucleotide Marker Panel, NCI Thesaurus)
