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    INSULIN

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Hormone secreted by the isles of Langerhans in the pancreas; regulates storage of glycogen in the liver and accelerates oxidation of sugar in cellsplay

    Classified under:

    Nouns denoting body parts

    Hypernyms ("insulin" is a kind of...):

    endocrine; hormone; internal secretion (the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect)

    hypoglycaemic agent; hypoglycemic agent (any of various agents that decrease the level of glucose in the blood and are used in the treatment of diabetes mellitus)

    Hyponyms (each of the following is a kind of "insulin"):

    Lente Iletin; Lente Insulin (trade names for forms of insulin that are used to treat diabetes mellitus)

    Humulin; recombinant human insulin (a form of insulin (trade name Humulin) made from recombinant DNA that is identical to human insulin; used to treat diabetics who are allergic to preparations made from beef or pork insulin)

    Credits

     Context examples: 

    Patients develop insulin resistance, leading to diabetes mellitus.

    (Berardinelli-Seip Congenital Lipodystrophy, NCI Thesaurus)

    A cell that composes the bulk of the islets of Langerhans and secretes insulin.

    (Beta Cell, NCI Thesaurus)

    The cause might be insulin resistance.

    (Metabolic Syndrome, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)

    BAIAP2 protein functions as an insulin receptor tyrosine kinase substrate and interacts with the dentatorubral-pallidoluysian atrophy gene, associated with a neurodegenerative disease.

    (BAI1-Associated Protein 2, NCI Thesaurus)

    It is a form of the hormone insulin that is made in the laboratory.

    (Apidra, NCI Dictionary)

    When it affects women in reproductive age, it causes virilization, high blood pressure, and increased insulin levels.

    (Ovarian Stromal Hyperthecosis, NCI Thesaurus)

    People with type 2 diabetes whose beta cells don't work properly have to inject insulin to keep their blood glucose levels stable.

    (New Potential Approach Found to Type 2 Diabetes Treatment, The Titi Tudorancea Bulletin)

    In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked them.

    (Pancreatic Diseases, NIH)

    Low insulin sensitivity/insulin resistance requires larger amounts of insulin to control blood glucose levels.

    (Exercise in pregnancy improves health of obese mothers by restoring their tissues, University of Cambridge)

    It may or may not be associated with inappropriate secretion of insulin and an associated clinical syndrome.

    (Pancreatic Insulin-Producing Neuroendocrine Tumor, NCI Thesaurus)


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