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INTERLEUKIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
Classified under:
Hypernyms ("interleukin" is a kind of...):
lymphokine (a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages))
Context examples:
A cancer vaccine consisting of a mixture of a murine lymphoma-derived idiotype and interleukin-2 (IL-2) encapsulated in dimyristoylphosphatidylcholine liposomes.
(Oncovax-ID/IL-2 Vaccine, NCI Thesaurus)
This allele, which encodes nuclear factor interleukin-3-regulated protein, is involved in the regulation of gene transcription.
(NFIL3 wt Allele, NCI Thesaurus)
Also called Proleukin and recombinant human interleukin-2.
(Aldesleukin, NCI Dictionary)
A "true human" (cloned from human B lymphocytes) monoclonal antibody directed against interleukin-1 alpha (IL1a) with potential antineoplastic activity.
(Anti-IL-1 alpha Monoclonal Antibody CA-18C3, NCI Thesaurus)
Inhibition of these processes results in suppression of the production of proinflammatory cytokines, such as tumor necrosis factor alpha and interleukin 6.
(Acai Berry Juice, NCI Thesaurus)
The muscle cells secreted interleukins 4 and 13, cellular proteins that stimulated the cancer cells to produce two additional proteins, annexin A5 and syncytin 1, which triggered the cancer cells to fuse together.
(Proximity to muscle cells may promote spread of prostate cancer cells, National Institutes of Health)
MyD88 is involved in interleukin 1 receptor (IL1R) and toll-like receptor (TLR) signaling.
(Adenovector-transduced AP1903-inducible MyD88/CD40-expressing Autologous PSMA-specific Prostate Cancer Vaccine BPX-201, NCI Thesaurus)
The high-risk group’s samples increased the proportion of allergy-promoting immune cells and production of interleukin-4, an allergy-associated cell-signaling protein.
(Infant gut microbes linked to allergy, asthma risk, NIH)
A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities.
(MVA-MUC1-IL2 Vaccine, NCI Thesaurus)
In addition to its pro-apoptotic effect, MCC activates monocytes and macrophages to produce various cytokines, including interleukin 6 (IL-6), IL-8, IL-12, IL-18, and tumor necrosis factor alpha (TNF-a).
(Mycobacterial Cell Wall-DNA Complex, NCI Thesaurus)
