| Health / Medical Topics |
Interleukin 3 Receptor Alpha
Encoded by human IL3RA Gene (Type I Cytokine Receptor 5 Family), 378-aa 43-kDa (precursor) Interleukin 3 Receptor Alpha is a type I membrane protein with a box 1 motif for JAK interaction/activation; a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding; and the ligand-binding alpha subunit of a heterodimeric cytokine receptor for Interleukin 3. Receptor binding to IL3 depends on the signal transducing beta subunit, shared by IL3-, IL5-, and CSF2/GM-CSF receptors. (NCI Thesaurus)
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Heterodimeric human Interleukin 3 Receptor is composed of 378-aa 43-kDa (precursor) Interleukin 3 Receptor Alpha and GM-CSF/IL-3/IL-5 Receptor Common Beta-Chain. IL3RA is…
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