Health / Medical Topics |
Interleukin-9
Definition 1
Human interleukin-9 protein (144 aa 16 kDa precursor) is encoded by the human interleukin-9 (IL9) gene. This glycoprotein is secreted by T-cells and macrophages. It is a cytokine growth factor that activates STAT proteins through IL-9R and may serve as a regulator of both lymphoid and myeloid systems. (NCI Thesaurus)
Definition 2
Factor that is thought to be a regulator of hematopoiesis. It has been shown to enhance the growth of human mast cells and megakaryoblastic leukemic cells as well as murine helper t-cell clones. IL-9 is a glycoprotein with a molecular weight of 32-39 that is derived from T-cells, and maps to human chromosome 5. (NLM, Medical Subject Headings)
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