Iratumumab

Definition 1

A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the tumor necrosis factor receptor superfamily found on activated lymphocytes. CD30 is over-expressed in various lymphoproliferative disorders, Hodgkin's disease and other lymphomas, and other cancers. (NCI Thesaurus)

Definition 2

A monoclonal antibody that is being studied in the treatment of some lymphomas. Monoclonal antibodies are produced in the laboratory and can locate and bind to cancer cells. (NCI Dictionary)

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IRAK4 wt Allele

Human IRAK4 wild-type allele is located in the vicinity of 12q12 and is approximately 29 kb in length. This allele, which encodes…

IRAK4 Gene

This gene plays a role in signal transduction and the immune response.

IRAK3 wt Allele

Human IRAK3 wild-type allele is located in the vicinity of 12q14.3 and is approximately 60 kb in length. This allele, which encodes…

IRAK3 Gene

This gene is involved in signal transduction and the immune response.