Irbesartan

A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI Thesaurus)

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Iratumumab

A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of…

Iraqi

Denotes the inhabitants of Iraq, a person from there, or their descendants elsewhere.

Iranian

Denotes the inhabitants of Iran, a person from there, or their descendants elsewhere.

IRAK4 wt Allele

Human IRAK4 wild-type allele is located in the vicinity of 12q12 and is approximately 29 kb in length. This allele, which encodes…

IRAK4 Gene

This gene plays a role in signal transduction and the immune response.