IRF6 wt Allele

Human IRF6 wild-type allele is located within 1q32.3-q41 and is approximately 18 kb in length. This allele, which encodes interferon regulatory factor 6 protein, is involved in the modulation of transcription. Mutation of the gene is associated with van der Woude syndrome and popliteal pterygium syndrome and genetic variation is a factor in orofacial cleft type 6. (NCI Thesaurus)

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IRF6 Gene

This gene plays a role in transcriptional regulation and the development of the palate.

IRF4 wt Allele

Human IRF4 wild-type allele is located within 6p25-p23 and is approximately 20 kb in length. This allele, which encodes interferon regulatory factor…

IRF4 Gene

This gene is involved in the regulation of B-cell differentiation and proliferation. It also plays a role in mediating the proliferation of…

IRF3 wt Allele

Human IRF3 wild-type allele is located within 19q13.3-q13.4 and is approximately 6 kb in length. This allele, which encodes interferon regulatory factor…

IRF3 Gene

This gene plays a role in the transcriptional activation of target genes.

IRF2BP2 wt Allele

Human IRF2BP2 wild-type allele is located in the vicinity of 1q42.3 and is approximately 5 kb in length. This allele, which encodes…