| Health / Medical Topics |
IRS1 wt Allele
Human IRS1 wild-type allele is located in the vicinity of 2q36 and is approximately 65 kb in length. This allele, which encodes insulin receptor substrate 1 protein, is involved in the progression of signaling from both insulin and cytokine-responsive receptors. (NCI Thesaurus)
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This gene plays a role in signal transduction and carbohydrate metabolism. It is involved in mediation of the insulin response.
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