JAK1 wt Allele

Human JAK1 wild-type allele is located within 1p32.3-p31.3 and is approximately 53 kb in length. This allele, which encodes tyrosine-protein kinase JAK1 protein, plays a role in signal transduction in the IFN (alpha, beta and gamma) signaling pathways. (NCI Thesaurus)

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JAK1 Gene

This gene plays a role in signal transduction.

Jak-STAT Signaling Pathway

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a…

JAK Inhibitor INCB047986

An orally bioavailable inhibitor of Janus-associated kinases (JAK), with potential antineoplastic activity. Upon oral administration, INCB047986 specifically binds to and inhibits the…

JAG2 wt Allele

Human JAG2 wild-type allele is located in the vicinity of 14q32 and is approximately 27 kb in length. This allele, which encodes…

JAG2 Gene

This gene plays a role in cell fate determination.

JAG1 wt Allele

Human JAG1 wild-type allele is located within 20p12.1-p11.23 and is approximately 36 kb in length. This allele, which encodes protein jagged-1, may…