Health / Medical Topics

    JAZF1 wt Allele

    Human JAZF1 wild-type allele is located within 7p15.2-p15.1 and is approximately 350 kb in length. This allele, which encodes juxtaposed with another zinc finger protein 1, may play a role in the modulation of transcription. A chromosomal aberration involving this gene, translocation t(7;17)(p15;q21) with the SUZ12 gene, is associated with endometrial stromal tumors. (NCI Thesaurus)




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