JC Virus

Definition 1

One of two polyomaviruses found in humans. JC virus can infect the respiratory system, kidneys, or brain, sometimes causing the fatal progressive multifocal leukoencephalopathy in the latter case. It is very widespread with approximately 80 percent of the adult population in the United States having antibodies to and JC. (from WordIQ.com) (NCI Thesaurus)

Definition 2

A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus. (NLM, Medical Subject Headings)

Definition 3

Any viral organism that can be assigned to the species JC polyomavirus. (NCI Thesaurus/CDISC)

Definition 4

isolated from brain of patient with progressive multifocal leucoencephalopathy; antibodies found in man, suggesting it is a common infection; experimentally virus is highly oncogenic in new-born hamsters. (NIH CRISP Thesaurus)

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