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Juvenile myelomonocytic leukemia
Pronunciation
Definition 1
A rare form of childhood leukemia in which cancer cells often spread into tissues such as the skin, lung, and intestines. Also called JMML. (NCI Dictionary)
Definition 2
A myelodysplastic/myeloproliferative neoplasm of childhood that is characterized by proliferation principally of the granulocytic and monocytic lineages. Myelomonocytic proliferation is seen in the bone marrow and the blood. The leukemic cells may infiltrate any tissue, however liver, spleen, lymph nodes, skin, and respiratory tract are the most common sites of involvement. The prognosis is usually poor. (NCI Thesaurus/WHO)
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