KAT6A/CREBBP Fusion Gene

A fusion gene that results from a chromosomal translocation t(8;16)(p11;p13) which fuses the 5' portion of the KAT6A gene to most of the coding region of the CREBBP gene. This rearrangement is associated with acute myeloid leukemia. (NCI Thesaurus)

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KAT6A wt Allele

Human KAT6A wild-type allele is located in the vicinity of 8p11 and is approximately 121 kb in length. This allele, which encodes…

KAT6A Gene

This gene is involved in both histone acetylation and transcriptional regulation.

KAT5 wt Allele

Human KAT5 wild-type allele is located within 11q13 and is approximately 8 kb in length. This allele, which encodes histone acetyltransferase KAT5…

KAT5 Gene

This gene plays a role in apoptosis, DNA repair and the regulation of chromatin remodeling.

KAT2B wt Allele

Human KAT2B wild-type allele is located within 3p24 and is approximately 114 kb in length. This allele, which encodes histone acetyltransferase KAT2B…

KAT2B Gene

This gene is involved in histone and nucleosome remodeling and transcriptional regulation.