Knowledge Base

A genus of non motile, Gram positive, non sporeforming bacterium assigned to the phylum Actinobacteria and the family Intrasporangiaceae.

Informal term for the generation of a mutant mouse in which the function of a particular gene has been completely eliminated, also…

Inactivation of specific genes by homologous recombination. Knockouts are often created in laboratory organisms such as yeast or mice so that scientists…

Replacement of a gene by an altered version of the same gene using homologous recombination resulting in a gain of function. One…

A handle, usually attached to a shaft allowing manual rotation of the shaft.

The mission of the Knight Cancer Institute is to translate discoveries into better ways to diagnose, prevent, and treat cancer. It became…