| Health / Medical Topics |
KRIT1 wt Allele
Human KRIT1 wild-type allele is located within 7q21-q22 and is approximately 102 kb in length. This allele, which encodes Krev interaction trapped protein 1, may play a role in integrin signaling modulation. Mutations in the gene, which encode for products that terminate prematurely, are a factor in familial cerebral cavernous malformations. (NCI Thesaurus)
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