| Health / Medical Topics |
L-Gossypol
The levo-enantiomer of an orally bioavailable polyphenolic aldehyde, derived primarily from unrefined cottonseed oil, with potential antineoplastic activity. Mimicking the inhibitory BH3 (Bcl-2 homology 3) domain of endogenous antagonists of Bcl-2, L-gossypol binds to and inhibits various anti-apoptotic Bcl-2 proteins, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. This agent has greater affinity for Bcl-2 proteins than racemic gossypol. (NCI Thesaurus)
YOU MAY ALSO LIKE
One of twenty amino acids (molecules that join together to form proteins). L-glutamic acid may help nerve cells send and receive information…
A catechin with the R configuration at C-2 and C-3.
L-dopachrome tautomerase (519 aa, ~59 kDa) is encoded by the human DCT gene. This protein is involved in the biosynthesis of…
A neuroendocrine tumor that arises from the gastrointestinal tract and produces glucagon-like peptides. Morphologically, it is characterized by the presence of…
A dietary supplement containing the levo-enantiomers of carnitine and tartrate with potential chemoprotective and antioxidant activities. L-carnitine L-tartrate increases fatty acid oxidation…
A form of carnitine, which is a substance made in muscle and liver tissue and found in certain foods, such as meat,…
