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    LAPTM4B wt Allele

    Human LAPTM4B wild-type allele is located in the vicinity of 8q22.1 and is approximately 146 kb in length. This allele, which encodes lysosomal-associated transmembrane protein 4B, may be involved in transport. Amplification of the gene may be associated with hepatocellular carcinoma and both anthracycline resistance and metastatic recurrence in breast cancer. (NCI Thesaurus)




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