| Health / Medical Topics |
LEF1 wt Allele
Human LEF1 wild-type allele is located within 4q23-q25 and is approximately 121 kb in length. This allele, which encodes lymphoid enhancer-binding factor 1 protein, is involved in the mediation of both transcription and signal transduction. Genetic variation may be associated with both the occurrence and relapse of acute lymphoblastic leukemia. (NCI Thesaurus)
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