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Ligand Binding Domain
A Binding Site Domain is a region of protein that physically interacts stereospecifically, and usually at high affinity, with a specific ligand, substrate, or a specific domain of some complex target biomolecule, such as a protein, lipid, carbohydrate, or nucleic acid. Typically, but not necessarily, the interaction results in protein conformational alteration and functional modification. (NCI Thesaurus)
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Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that ordinarily…
An ion, molecule or molecular group that binds to a substance to form a larger complex.
The fibrous tissues connecting the laminae of neighboring vertebrae beginning at C2 and ending at S1.
Band of fibrous tissue connecting bone to bone or cartilage to bone thereby supporting or strengthening a joint.
Human LIG4 wild-type allele is located within 13q33-q34 and is approximately 11 kb in length. This allele, which encodes DNA ligase 4…
This gene plays a critical role in the regulation of nonhomologous DNA end joining and in V(D)J recombination.
