| Health / Medical Topics |
Linkage Disequilibrium Mapping
Linkage disequilibrium (LD) mapping is a procedure for determining the non-random association of alleles at two or more loci on a chromosome. It is based on the premise that regions adjacent to a gene of interest are transmitted through the generations along with that gene and can be identified by the specific pattern of markers (haplotypes) that they contain, so that detection of haplotypes that are shared more frequently among groups of individuals recruited for a disease or trait can be used to locate specific genes. Linkage-disequilibrium (LD) mapping is useful in identifying genes involved in complex diseases. (NCI Thesaurus)
YOU MAY ALSO LIKE
Nonrandom association of linked genes; the occurrence of some genes together, more often than would be expected based upon their physical separation,…
The textual representation of the linked page.
Link Guanine Nucleotide Exchange Factor II, encoded by the Link-GEFII gene, is a Rap guanine nucleotide exchange factor enriched highly in the…
A traditional unit of length equal to 1/100 of a Ramsden's chain, exactly 1 foot.
A traditional unit of length equal to 1/100 of a Gunter's chain, exactly 7.92 inches or 201.168 mm.
A rare type of stomach cancer that begins in the lining of the stomach and spreads to the muscles of the stomach…
