| Health / Medical Topics |
LMNA wt Allele
Human LMNA wild-type allele is located within 1q21.2-q21.3 and is approximately 25 kb in length. This allele, which encodes lamin-A/C protein, plays a role in nuclear stability and chromatin structure. Mutatations in the LMNA gene produce abberant alleles that have been linked to Hutchinson-Gilford progeria syndrome. (NCI Thesaurus)
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