Lobular neoplasia

Pronunciation

Definition 1

A condition in which abnormal cells are found in the lobules (glands that make milk) of the breast. This condition rarely becomes cancer. However, having lobular neoplasia in one breast increases the risk of breast cancer in either breast. Types of lobular neoplasia include atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). Also called LIN and lobular intraepithelial neoplasia. (NCI Dictionary)

Definition 2

A spectrum of non-invasive neoplastic lesions that arise from the terminal ductal lobular units of the breast. There is atypical small epithelial cell proliferation. Pagetoid involvement of the terminal ducts may or may not be present. In the minority of cases, there is a risk for subsequent development of invasive ductal or invasive lobular carcinoma. (NCI Thesaurus)

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