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LOCALIZATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A determination of the place where something is
Example:
he got a good fix on the target
Synonyms:
fix; localisation; localization; locating; location
Classified under:
Nouns denoting acts or actions
Hypernyms ("localization" is a kind of...):
determination; finding (the act of determining the properties of something, usually by research or calculation)
Hyponyms (each of the following is a kind of "localization"):
echo sounding; echolocation (determining the location of something by measuring the time it takes for an echo to return from it)
Derivation:
localize (locate)
localize (identify the location or place of)
Sense 2
Meaning:
(physiology) the principle that specific functions have relatively circumscribed locations in some particular part or organ of the body
Synonyms:
localisation; localisation of function; localisation principle; localization; localization of function; localization principle
Classified under:
Nouns denoting cognitive processes and contents
Hypernyms ("localization" is a kind of...):
principle; rule (a rule or law concerning a natural phenomenon or the function of a complex system)
Domain category:
physiology (the branch of the biological sciences dealing with the functioning of organisms)
Hyponyms (each of the following is a kind of "localization"):
lateralisation; laterality; lateralization (localization of function on either the right or left sides of the brain)
Context examples:
NAG has 2 clusters of nuclear localization signals, one in the N-terminus of the longer variant and the other in the common C-terminus.
(Neuroblastoma-Amplified Sequence, NCI Thesaurus)
This allele, which encodes myomegalin protein, is involved in the localization of phosphodiesterase activity.
(PDE4DIP wt Allele, NCI Thesaurus)
This gene may play a role in signal transduction, sugar transport and protein localization.
(PEA15 Gene, NCI Thesaurus)
This allele, which encodes astrocytic phosphoprotein PEA-15 protein, may be involved in the modulation of signaling, transport of carbohydrates and protein localization.
(PEA15 wt Allele, NCI Thesaurus)
The neomycin phosphotransferase gene product has no direct therapeutic value; it serves as a molecular marker to monitor the presence and localization of the PG13/Lnc8-transduced T-lymphocytes in the host.
(PG13/LNc8 Retroviral Transduced Cloned T-Cells, NCI Thesaurus)
This gene plays a role in protein complex localization.
(PDE4DIP Gene, NCI Thesaurus)
The Nurf301 subunit contains a bromodomain transcription factor domain, a zinc finger binding domain, nuclear localization signals, and motifs associated with rapid protein degradation.
(NURF, NCI Thesaurus)
This allele, which encodes merlin protein, plays a role in the mediation of protein localization, cytoskeletal conformation and ion transport.
(NF2 wt Allele, NCI Thesaurus)
Treatment with FK506, a specific calcineurin inhibitor, prevents nuclear localization of NF-ATc4.
(NFAT Pathway, NCI Thesaurus/BIOCARTA)
This protein is involved in centrosome localization.
(Ninein, NCI Thesaurus)
