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LOCUS
| Pronunciation (US): |  | (GB): | |
Irregular inflected form: loci
I. (noun)
Sense 1
Meaning:
The set of all points or lines that satisfy or are determined by specific conditions
Example:
the locus of points equidistant from a given point is a circle
Classified under:
Nouns denoting groupings of people or objects
Hypernyms ("locus" is a kind of...):
set ((mathematics) an abstract collection of numbers or symbols)
Sense 2
Meaning:
The specific site of a particular gene on its chromosome
Classified under:
Nouns denoting spatial position
Hypernyms ("locus" is a kind of...):
site; situation (physical position in relation to the surroundings)
Sense 3
Meaning:
The scene of any event or action (especially the place of a meeting)
Synonyms:
Classified under:
Nouns denoting spatial position
Hypernyms ("locus" is a kind of...):
scene (the place where some action occurs)
Context examples:
A fusion gene that results from a chromosomal translocation t(11;22)(q13;q11) which places the CCND1 gene on the 5' side of the immunoglobulin light chain locus IGLC1 gene.
(CCND1/IGLC1 Fusion Gene, NCI Thesaurus)
A translocation of this gene and the IGH gene locus may be associated with splenic marginal zone B-cell lymphoma.
(CCND3 wt Allele, NCI Thesaurus)
This locus includes four protein-encoding genes, CYP3A4, CYP3A5, CYP3A7 and CYP3A43, and two pseudogenes, CYP3A5P1 and CYP3A5P2.
(CYP3A Gene Locus, NCI Thesaurus)
Loci number in the thousands but each locus shows a distinctive repeat unit.
(Minisatellite Repeat, NCI Thesaurus)
Has platelet storage disease associated with the red-eyed yellow locus, as described by Raymond and Dodds (1975) for the FH strain.
(E3, Rat Strain, NCI Thesaurus)
Measure of histocompatibility at the HL-A locus.
(Mixed Lymphocyte Reaction Test, NCI Thesaurus)
By affecting the balance of chromatin in heterochromatin and euchromatin at specific gene loci, this protein acts as a candidate tumor suppressor.
(Chromobox Protein Homolog 5, NCI Thesaurus)
Fragile sites are designated by the letters "fra" followed by the designation for the specific chromosome and locus.
(Chromosome Fragile Site, NCI Thesaurus)
Cis-acting locus is a section of DNA that affects the activity of DNA sequences on that same molecule of DNA.
(Cis-Acting Sequence, NCI Thesaurus)
A set of genetic loci where each locus contains either a mononucleotide (single base pair) repeat or a dinucleotide (two nucleotide subunits) repeat sequence.
(Mononucleotide and Dinucleotide Marker Panel, NCI Thesaurus)
