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MACULAR DEGENERATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Eye disease caused by degeneration of the cells of the macula lutea and results in blurred vision; can cause blindness
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("macular degeneration" is a kind of...):
degeneration; devolution (the process of declining from a higher to a lower level of effective power or vitality or essential quality)
eye disease (any disease of the eye)
Hyponyms (each of the following is a kind of "macular degeneration"):
age-related macular degeneration; AMD (macular degeneration that is age-related)
Context examples:
Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the findings of a study.
(No evidence that calcium increases risk of age-related macular degeneration, National Institutes of Health)
In previous studies, activation of the complement system, which mediates some aspects of inflammation, worsens damage in age-related macular degeneration (AMD), a leading cause of blindness in people age 65 years and older.
(Immune system can slow degenerative eye disease, National Institutes of Health)
Dr. Chew leads the Age-Related Eye Disease Study (AREDS), which was designed to investigate a combination of nutritional supplements for slowing age-related macular degeneration (AMD), a major cause of vision loss.
(Study shows no benefit of omega-3 or other nutritional supplements for cognitive decline, NIH)
The findings point to potential therapies for controlling inflammation and slowing progression of rare retinal diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD).
(Immune cells in the retina can spontaneously regenerate, National Institutes of Health)
National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration (AMD), a leading cause of vision loss and blindness among people age 65 and older.
(New study about genes linked to age-related macular degeneration, National Institutes of Health)
Mutation of the gene is associated with basal laminar drusen, complement factor H deficiency, hemolytic uremic syndrome atypical type 1, and age-related macular degeneration type 4.
(CFH wt Allele, NCI Thesaurus)
Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced dry form of age-related macular degeneration (AMD).
(Researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration, National Institutes of Health)
Age-related macular degeneration is most often seen in people who are over the age of 50.
(Age-related macular degeneration, NCI Dictionary)
