Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma

Definition 1

This type of lymphoma is not frequently seen in the western hemisphere. Clinically, with the exception of anaplastic large cell lymphoma, mature T- and NK-cell lymphomas are among the most aggressive of all hematopoietic neoplasms. Representative disease entities include mycosis fungoides, angioimmunoblastic T-cell lymphoma, hepatosplenic T-cell lymphoma, and anaplastic large cell lymphoma. (NCI Thesaurus)

Definition 2

A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment. (NLM, Medical Subject Headings)

Definition 3

One of a group of aggressive (fast-growing) non-Hodgkin lymphomas that begins in mature T lymphocytes (T cells that have matured in the thymus gland and goes to other lymphatic sites in the body, including lymph nodes, bone marrow, and spleen.) (NCI Dictionary)

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