Health / Medical Topics |
MDM4 Gene
This gene plays a role in cell cycle arrest. (NCI Thesaurus)
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Human MDM2 wild-type allele is located within 12q14.3-q15 and is approximately 32 kb in length. This allele, which encodes ubiquitin-protein ligase E3…
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A single nucleotide polymorphism in the MDM2 gene associated with an earlier onset of tumors in both sporadic and hereditary cancers. …
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An orally available MDM2 (murine double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, MDM2 inhibitor DS-3032b binds to, and…
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This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.
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An orally available, small molecule, antagonist of MDM2 (mouse double minute 2; Mdm2 p53 binding protein homolog), with potential antineoplastic activity. RO5503781…
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An MDM2 (human homolog of double minutes-2; HDM2) antagonist with potential antineoplastic activity. RO5045337 binds to MDM2, thereby preventing the binding of…
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