MDM4 wt Allele

Human MDM4 wild-type allele is located in the vicinity of 1q32 and is approximately 34 kb in length. This allele, which encodes protein Mdm4, is involved in cell cycle checkpoint regulation. Aberrant gene expression is associated with retinoblastoma. (NCI Thesaurus)

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MDM4 Gene

This gene plays a role in cell cycle arrest.

MDM2 wt Allele

Human MDM2 wild-type allele is located within 12q14.3-q15 and is approximately 32 kb in length. This allele, which encodes ubiquitin-protein ligase E3…

MDM2 SNP309 Allele

A single nucleotide polymorphism in the MDM2 gene associated with an earlier onset of tumors in both sporadic and hereditary cancers. …

MDM2 Inhibitor DS-3032b

An orally available MDM2 (murine double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, MDM2 inhibitor DS-3032b binds to, and…

MDM2 Gene

This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.

MDM2 Antagonist RO5503781

An orally available, small molecule, antagonist of MDM2 (mouse double minute 2; Mdm2 p53 binding protein homolog), with potential antineoplastic activity. RO5503781…