Medical Topics
A state of the information pertaining to the entity associated with a clinical study protocol indicating whether this information is active or… »
A branch of computer or library science relating to the storage, locating, searching, and selecting, upon demand, relevant data on a given… »
Refers to data that is useful in forming an opinion or judging an outcome. »
A process in which patients are given important information, including possible risks and benefits, about a medical procedure or treatment, a clinical… »
The date (and time) the patient gives consent to a surgical or medical procedure or participation in a clinical study after achieving… »
A taxonomic category of related organisms ranking below a subclass and above an order. »
A lymph node located in the area below the clavicle. »
The region below the clavicle. »
Any point mutation occuring within the protein-coding region of a gene, and which results in a retention of the reading frame of… »
The liquid, solid or semi-solid lying below a liquid residue, which is separated by crystallization, precipitation or centrifugation of a biological… »
An artery arising from the third portion of the maxillary artery at the trunk and running along the infraorbital canal with the… »
A taxonomic category of related organisms ranking below a suborder and above a family. »
A technique in which abnormal tissue is exposed to a burst of infrared light (a type of radiation). This causes blood in… »
The use of an intense beam of light, such as a laser, to seal off blood vessels or destroy tissue. »
Electromagnetic radiation with wavelengths between 750 nanometers and 1 millimeter, between those of visible light and microwaves. This portion of the electromagnetic… »
A spectrometric method that determines the type and concentration of elements or chemicals in a sample, based upon the principle that the… »
In medicine, a procedure in which an infrared camera (one that senses heat) is used to measure temperature differences on the surface… »
One of the four muscles comprising the rotator cuff that is triangular in shape and extends from the infraspinatus fossa of the… »
The basic facilities, equipment, or underlying framework that are necessary for a system or organization to function. »
NIH Emphasis Area: Infrastructure activities are new or expanded programs in the following: Research Training; Shared Instrumentation and Services; Technology Development; Information… »
Establish appropriate infrastructure for the conduct of HIV research domestically and internationally. »
Any of the following subarachnoid cisterns: anterior, lateral, posterior and superior infratentorial cistern. »
A benign or malignant neoplasm that occurs in brain parenchymal tissue below the tentorium cerebelli. »
The lower back part of the brain that contains the cerebellum and brain stem. Examples of tumors that form in the infratentorium… »
Not occurring regularly or at short intervals. »
The anterior valvule or leaflet that comprises the tricuspid valve of the heart. »
The funnel shaped portion of the fallopian tube proximal to the fimbrial segment and most distal to the uterus. »
Any of various funnel-shaped parts of the body. »
A method of putting fluids, including drugs, into the bloodstream. Also called intravenous infusion. »
Intravenous nursing practice involves all aspects of infusion therapy, including phlebotomy, intravenous peripheral and central access line placement (PICC), chemotherapy, hyperalimentation,… »
Issue associated with the device failing to deliver liquids or gases as intended (e.g. delivering drugs at incorrect rate, issues with drawing… »
A method of putting fluids, including drugs, into the bloodstream. »
The volume of a substance injected into a subject in a unit time. »
The anatomic site through which fluid is introduced into the body. »
Leakage of a pharmacologic or a biological substance from the infusion site into the surrounding tissue. Signs and symptoms include induration, erythema,… »
A reaction to the infusion of pharmacological or biological substances. Symptoms may appear within minutes to hours following the infusion and may… »
Human ING1 wild-type allele is located within 13q34 and is approximately 8 kb in length. This allele, which encodes inhibitor of growth… »
Human ING2 wild-type allele is located in the vicinity of 4q35.1 and is approximately 6 kb in length. This allele, which encodes… »
A selective small-molecule activator of protein kinase C (PKC) isolated from the plant Euphorbia peplus with potential antineoplastic activity. Ingenol mebutate activates… »
Eating habits and their role in human disease »
A glycogen phosphorylase inhibitor with antihyperglycemic and cardioprotective activities. Ingliforib inhibits glycogen phosphorylase, the rate-limiting enzyme in glycogenolysis, thereby preventing the release… »
That which enters into a compound, or is a component part of any combination or mixture; an element; a constituent. »
Excessive lateral nail growth into the nail fold. Because the lateral margin of the nail acts as a foreign body, inflammation and… »
The oblique anatomic tunnel in the anterior lower abdomen. In males it conveys the spermatic cord structures and is the passage through… »
The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region. »
A superficial or deep lymph node located in the inguinal area. »
Surgical removal of one or more inguinal lymph nodes. »
An operation in which the testicle is removed through an incision in the groin. »
The lower region of the anterior abdominal wall located laterally to the pubic region. »
The surgical removal of superficial inguinal lymph nodes and deep femoral lymph nodes. »
This gene plays a role in negatively regulating stromal cell proliferation in the gonads. It is also involved in cell growth and… »
Human INHA wild-type allele is located within 2q33-q36 and is approximately 3 kb in length. This allele, which encodes inhibin alpha chain… »
Vaporized active and/or inert ingredient(s) intended for administration by inhalation. »
Powdered medication inhaled as a measured dose. »
Liquid medication intended to be inhaled. »
If you're a parent, you may fear that your kids will use drugs such as marijuana or LSD. But you may not… »
In medicine, refers to the act of taking a substance into the body by breathing. »
A dosing unit equal to the amount of active ingredient(s) contained in an inhalation. »
There are a variety of substances you can inhale that can cause acute internal injuries. Particles in the air from… »
Administration of a substance in the form of a gas, aerosol, or fine powder via the respiratory tract, usually by oral or… »
The branch of toxicology focusing on the health effects of inhaled poisons. »
A valve designed to regulate the flow of gases into a respirator or respiration system. »
A device for giving medicines in the form of a spray that is inhaled (breathed in) through the nose or mouth. Inhalers… »
A capsule composed of powders intended for oral inhalation. This dose form may also refer to capsules that are intended for use… »
A dosing unit equal to the amount of active ingredient(s) contained in an inhaler. »
A container of medication intended to refill an inhaler. »
A dosing unit equal to the amount of active ingredient(s) contained in an inhaler refill. »
This gene is involved in the negative regulation of stromal cell proliferation in the gonads. It also plays a role in cell… »
Human INHBA wild-type allele is located within 7p15-p13 and is approximately 11 kb in length. This allele, which encodes inhibin beta A… »
This gene plays a role in the negative regulation of stromal cell proliferation in the gonads. It is also involved in cell… »
Human INHBB wild-type allele is located within 2cen-q13 and is approximately 6 kb in length. This allele, which encodes inhibin beta B… »
The manner in which a particular genetic trait or disorder is passed from one generation to the next. »
Transmitted through genes that have been passed from parents to their offspring (children). »
A rare disorder in which a person’s bone marrow is unable to make enough blood cells and there is a family history… »
A type of inherited disorder in which there is a higher-than-normal risk of certain types of cancer. Inherited cancer syndromes are caused… »
A very rare disorder in which the bone marrow doesn’t make enough red blood cells. It is usually seen in the first… »
A hereditary disorder that affects the sensory and/or motor nerves or the autonomic nerves. »
Inhibins are peptide hormones, secreted by the follicular cells of the ovary and by the testis, that negatively regulate the synthesis and… »
Gonadal glycoprotein hormone, Inhibin A, consists of an alpha subunit covalently linked to a beta-A subunit and strongly inhibits pituitary FSH… »
The determination of the amount of inhibin A present in a sample. »
Inhibin alpha chain (366 aa, ~40 kDa) is encoded by the human INHA gene. This protein is involved in the negative regulation… »
Inhibin B, consisting of an alpha subunit and a beta B subunit linked by disulphide bonds, is a heterodimer hormone produced by… »
The determination of the amount of inhibin B present in a sample. »
Inhibin beta A chain (426 aa, ~47 kDa) is encoded by the human INHBA gene. This protein plays a role in the… »
Inhibin beta B chain (407 aa, ~45 kDa) is encoded by the human INHBB gene. This protein is involved in the modulation… »
The interference with or prevention of an action or response even though the stimulus for that action or response is present. … »
Inhibition of Amyloidogenesis is a process that prevents the formation or growth of amyloid structures. »
Intercellular, cellular, and subcellular mechanisms that inhibit or block the induction, promotion, maintenance, or completion of cell division in cancer cells. … »
Inhibition of Cell Proliferation involves intercellular, cellular, and subcellular mechanisms that inhibit or block the induction, promotion, maintenance, or completion cell… »
The drug Gleevec (also known as imatinib mesylate or STI-571) was approved by the FDA in 2001 for the treatment of CML,… »
Huntington's disease is a neurodegenerative condition caused by a dominant mutation in a gene encoding a protein now called huntingtin. Large… »
Cellular transformation is accompanied by many cellular changes, including uncontrolled proliferation, loss of the differentiated cell morphology, and invasion of the extracellular… »
Inhibitor of growth protein 1 (422 aa, ~47 kDa) is encoded by the human ING1 gene. This protein is involved in the… »
Inhibitor of growth protein 2 (280 aa, ~33 kDa) is encoded by the human ING2 gene. This protein plays a role in… »
Inhibitor of nuclear factor kappa-B kinase subunit beta (756 aa, ~87 kDa) is encoded by the human IKBKB gene. This protein is… »
Inhibitor of nuclear factor kappa-B kinase-interacting protein (350 aa, ~39 kDa) is encoded by the human IKBIP gene. This protein plays a… »
Nerve impulses that act to inhibit or stop a particular physiological activity or response. »
A synapse in which the firing of the presynaptic cell reduces the probability of firing of the postsynaptic cell. »
A substance being studied in the treatment of some types of cancer. Iniparib may kill cancer cells. Also called BSI-201. »
The first measured concentration of a compound in a substance. In pharmacology, the initial concentration is given only for bolus IV… »
Initial concentration divided by the body mass index. Given only for bolus IV models. »
Initial concentration divided by the dose. Given only for bolus IV models. »
Initial concentration divided by the surface area. Given only for bolus IV models. »
Initial concentration divided by the weight. Given only for bolus IV models. »
The initial volume of distribution for a substance administered by bolus intravascular dosing. »
The initial volume of distribution for a substance administered by bolus intravascular dosing divided by the body mass index. »
The initial volume of distribution for a substance administered by bolus intravascular dosing divided by the dose. »
The initial volume of distribution for a substance administered by bolus intravascular dosing divided by the surface area. »
The initial volume of distribution for a substance administered by bolus intravascular dosing divided by the weight. »
The act of starting something; an act that sets in motion some course of events. »
One of several soluble proteins involved in the initiation of protein or RNA synthesis. »
Something that sets into motion some course of events; a device that activates or releases or causes something to happen. »
An injectable form of a polysaccharide isolated from the radix of Astragalus membranaceus (PG2), used in traditional Chinese medicine, with potential hematopoiesis… »
A substance intended for injection. »
A suspension intended for injection that is designed to release active and/or inert ingredient(s) at a controlled, prolonged rate so as to… »
A foam intended for parenteral administration. »
A substance composed of complexed active and/or inert ingredient(s) with natural or synthetic lipids that is intended for injection. »
A suspension composed of active and/or inert ingredient(s) encapsulated in liposomes and intended for injection. »
A freeze dried powder intended for injection following reconstitution with a suitable solvent. »
A solution intended for injection. »
A suspension intended for injection and is sonicated while a gas is bubbled through the suspension resulting in the creation of microspheres… »
A suspension intended for injection. »
The activity of a tracer injected at the beginning of a scan. »
Use of a syringe and needle to push fluids or drugs into the body; often called a "shot." »
Administration of a drug into a location within the body; this can be achieved either through an established access or via a… »
The anatomic site at which a medication or a vaccine is injected. »
An intense reaction (usually immunologic) developing at the site of injection »
A system designed to pump a gas or liquid into a space or environment. »
An injury is damage to your body. It is a general term that refers to harm caused by accidents, falls, blows, burns,… »
Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural… »
The anatomic site at which damage or harm was suffered. »
Damage to the carotid artery. Causes include blunt injuries (e.g., motor vehicle accidents and sports-related injuries) and penetrating traumas (e.g., gunshot and… »
Damage to the inferior vena cava from traumatic or pathologic processes. »
Damage to the jugular vein from traumatic or pathologic processes. »
Damage to liver structure or function due to trauma or toxicity. »
Damage to the superior vena cava from traumatic or pathologic processes. »
A class of disorders that encompasses conditions resulting from an injury, poisoning or procedure. »
A valve that controls the flow of fluids in through the wall of a chamber. »
A drug used to treat advanced renal cell carcinoma (the most common type of kidney cancer). It is used in patients who… »
Innate Bone Remodeling takes place in the adult skeleton at discrete foci. The continuous turnover of bone matrix and mineral that involves… »
A synthetic, 5-amino acid peptide and Innate Defense Regulator (IDR), with immunomodulating, anti-inflammatory, anti-infective and anti-mucositis activities. Upon intravenous administration, SGX942 binds… »
A recombinant 19 kDa protein derived from the Apicomplexa protozoan Eimeria with potential immunostimulating and antitumor activities. Upon administration, innate immunostimulator rBBX-01… »
The inner component of a double-cannula device, designed to be easily removable and replaceable. »
The medial corner of the eye where the upper and lower eyelids join. »
The cluster of cells inside the blastocyst. These cells give rise to the embryo and ultimately the fetus. The ICM may be… »
The older and more populated and (usually) poorer central section of a city. »
The portion of the ear located within the temporal bone that is involved in both hearing and balance and includes the semicircular… »
A non-neoplastic or neoplastic disorder affecting the inner ear. Causes are inner ear infections, head injuries, and neoplasms (e.g., acoustic schwannoma). Symptoms… »
A viral or bacterial infection that affects the inner ear. Signs and symptoms include hearing loss, vertigo, nausea, and tinnitus. … »
A rare benign adipose tissue neoplasm of the internal auditory canal, often presenting as an acoustic tumor. It may be intermixed with… »
A rare neoplasm that arises from the inner ear. Representative examples include lipoma and acoustic schwannoma. »
The inner most layer of the enamel organ. It is derived from the ectoderm of the dental lamina and differentiates into ameloblasts… »
A cell situated on the inner most layer of the basilar membrane of the cochlea. Each cell has multiple, sensitive strands called… »
The cytoplasmic-facing layer of the plasma membrane. »
A retinal layer composed of the basal lamina of Muller's cells. »
The inner mitochondrial membrane encloses a fluid-filled matrix and is elaborately folded with shelf-like cristae projecting into the matrix. The components of… »
The cells forming the inner spiraled tunnel walls in the organ of Corti within the inner ear. »
The portion of the photoreceptor cell between the outer segment and nucleus that is divided into an ellipsoid and myoid section. … »
A tall, slender cell extending from the basilar membrane to the free surface of the organ of Corti. Each cell surrounds an… »
The internal wall of the tympanic cavity. »
The wall facing the inside of the vestibule of the inner ear. »
A drug that is used with another drug, warfarin, to treat blood clots that form deep in the veins and to prevent… »
An artery arising from the aortic arch that divides into the right common carotid and right subclavian arteries. »
One of two arteries (right common carotid and right subclavian) that branch off of the innominate artery. »
A isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties. INO-1001 inhibits PARP,… »
To implant microbes or infective materials, introduce immune serum, vaccines of various kinds, and other antigenic materials for preventive, curative, or experimental… »
Describes a condition that cannot be treated by surgery. »
A substance with carcinogenic potential that does not have carbon or its derivatives incorporated in its structure. »
A broad class of substances, principally from mineral sources of non-biological origin, encompassing all those that do not include carbon and its… »
A field of chemistry concerned with the study of inorganic compounds and ions. »
Agents that inhibit Inosine 5'-Phosphate Dehydrogenase, an regulatory enzyme of guanosine triphosphate biosynthesis, causing possible inhibition of cell proliferation and malignancy. … »
A toxic purine analogue. Inosine dialdehyde inhibits ribonucleotide reductase, resulting in decreased synthesis of DNA, RNA, and proteins, and G2/M-phase cell cycle… »
Any substance that inhibits inosine monophosphate dehydrogenase, an enzyme that catalyzes the conversion of inosine monophosphate to xanthosine monophosphate, the rate-limiting step… »
An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by… »
Inosine-5'-monophosphate dehydrogenase 1 (514 aa, ~55 kDa) is encoded by the human IMPDH1 gene. This protein plays a role in guanine nucleotide… »
Inosine-5'-monophosphate dehydrogenase 2 (514 aa, ~56 kDa) is encoded by the human IMPDH2 gene. This protein is involved in nucleotide metabolism. … »
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Inositol helps cells… »
Widely expressed by human ITPR1 Gene (InsP3R Family) as 8 potential alternative isoforms, 2758-aa 314-kDa integral endoplasmic reticulum membrane protein Inositol 1,4,5-Triphosphate… »
A phosphatidylinositol with phosphate covalently bound in the 4 and 5 positions of the inositol group. Inositol 1,4,5-trisphosphate acts as an intermediate… »
A substance found in many foods that come from plants, including corn, wheat, rice, and soybeans, and in large amounts in cereals… »
A niacin formulation that contains no free niacin, but can be hydrolyzed to release free niacin in vivo. Use of inositol niacinate… »
A CD22-targeted cytotoxic immunoconjugate composed of a humanized IgG4 anti-CD22 antibody covalently linked to N-acetyl-gamma-calicheamicin dimethyl hydrazide (CalichDMH) with potential antineoplastic… »
A free standing rehabilitation center or a rehabilitation center within a general medical facility. »
This gene is involved in phosphatidylinositol metabolism. »
Human INPP4B wild-type allele is located in the vicinity of 4q31.21 and is approximately 824 kb in length. This allele, which encodes… »
This gene is involved in the modulation of signaling. »
A protein encoded by the INPP5D gene. »
Human INPP5D wild-type allele is located in the vicinity of 2q37.1 and is approximately 192 kb in length. This allele, which encodes… »
A benzoquinone-based antineoplastic agent. Inproquone was never marketed. »
A time varying function providing causal changes to a system it acts upon. »
A genus of Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria and the family Rhodospirillaceae. »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is oxidase and beta galactosidase positive and… »
A laboratory test result which indicates increased ratio of the patient's prothrombin time to a control sample in the blood. »
Human INS wild-type allele is located in the vicinity of 11p15.5 and is approximately 2 kb in length. This allele, which encodes… »
A substance being studied in the diagnosis of lung diseases, including lung cancer. It helps bring up a sample of mucus from… »
A taxonomic class of arthropods that includes praying mantises, dragonflies, grasshoppers, true bugs, flies, bees, wasps, ants, butterflies, moths, and beetles. … »
Most insect bites are harmless, though they sometimes cause discomfort. Bee, wasp, and hornet stings and fire ant bites usually hurt. Mosquito,… »
A solid or semi-solid intended for administration within the body. »
A dosing unit equal to the amount of active ingredient(s) contained in an insert. »
Mechanical Circulatory Support was inserted during a non-Percutaneous Coronary Intervention (PCI) procedure. »
Mechanical Circulatory Support was inserted during the procedure. »
Mechanical Circulatory Support was inserted during the procedure after Percutaneous Coronary Intervention (PCI) started. »
Any rearrangement to the genomic content that adds one or more extra nucleotides into the DNA. Insertions may be reversible, particulary if… »
Insertion of one or more nucleotides into a DNA sequence. An insertion mutation abnormality can result in a frame shift abnormality if… »
Mutagenesis of DNA by the insertion of one or more bases. »
This gene plays a role in embryonic development and several cellular functions. »
Human INSL4 wild-type allele is located in the vicinity of 9p24 and is approximately 4 kb in length. This allele, which encodes… »
Amount of solar radiation received on a given body or in a given area. »
The fraction of non-starch polysaccharides which are not soluble in water. »
Taking ambient air into the lungs; breathing in. »
The maximum volume of air a subject can inhale into the lungs after a tidal exhalation (IRV plus TV). »
The change in IC following administration of a bronchodilator relative to the pre-treatment IC value. »
The maximum volume of air a subject can inhale into the lungs after a tidal inhalation. »
A valve designed to regulate the flow of gases into a respirator or respiration system. »
A test to evaluate amount of oxygen taken up by arterial blood and expressed as a fraction of total oxygen of inspired… »
A syndrome characterized by persistent jaundice, hemolytic anemia, and hepatomegaly in a newborn. It is characterized by the presence of inspissated bile… »
Human INSR wild-type allele is located within 19p13.3-p13.2 and is approximately 177 kb in length. This allele, which encodes insulin receptor protein,… »
This gene is thought to play a role in insulin regulation; however, the exact function is not known. »
Human INSRR wild-type allele is located within 1q21-q23 and is approximately 18 kb in length. This allele, which encodes insulin receptor-related protein,… »
The tumor is confined to the original site of growth; no metastasis. »
The tumor is unilateral and the resection is grossly incomplete; no evidence of lymph node involvement. »
The tumor is unilateral and the resection is complete or incomplete; ipsilateral lymph nodes are involved by tumor. »
The tumor extends across the midline and the regional lymph nodes may or may not be involved by tumor; or the tumor… »
Tumor spread to distant lymph nodes, bone marrow, bones, and liver. »
Patients are less than one year old with localized primary tumor and dissemination limited to the following specific anatomic sites: liver, skin,… »
Issue associated with unsatisfactory installation, configuration, and/or setup of a specific device or technology. »
A class of professional or vocational positions of employment that involve installation, maintenance or repair. »
A data type comprised of an identifier that uniquely characterizes an individual entity. »
Data type unique identifier within a particular context. »
In medicine, a method used to put a liquid into the body slowly or drop by drop. »
The Institute for Cancer Prevention is an NCI-designated Cancer Center. Since 2001, the Institute has been rapidly expanding its translational research and… »
As part of the National Academy of Science, identifies, for study and analysis, important issues and problems that relate to health and… »
An established society, corporation, foundation or other organization founded and united for a specific purpose, e.g. for health-related research; also used to… »
The patient will be admitted into an alternative facility not listed. »
Additional support to assist in meeting living costs may be provided by the grantee training institution. This supplement does not require… »
A self-regulating entity mandated by federal law to be established at an institution that uses laboratory animals for research or instructional purposes… »
An institutional-level board mandated by federal law for oversight of recombinant DNA research and work involving biohazardous agents taking place at that… »
The Institutional Commitment section of the Cancer Center Support Grant Application includes a schematic description of the Cancer Center's position within the… »
National Research Service Award (NRSA) institutional training grants (T32) enable eligible institutions to develop or enhance predoctoral and postdoctoral research training opportunities… »
A group of scientists, doctors, clergy, and patient advocates that reviews and approves the detailed plan for every clinical trial. Institutional Review… »
A document containing the determination of the Institutional Review Board (IRB) that the clinical study with human subject participation has been reviewed… »
A date on which the Institutional Review Board (IRB) approved a clinical study protocol for execution at the particular institution or… »
A message describing how something is to be done. »
Issue associated with the accuracy and appropriateness of any written, printed, graphic or audio/visual matter that is supplied with a medical device… »
Information obtained from an electronic device that is used to measure material properties. »
A section of the Older Americans Resource Scale Multidimensional Functional Assessment Questionnaire (OMFAQ) that seeks information about a person's functional ability to… »
Any object, or item of electrical or electronic equipment, which is designed to carry out a specific function or set of… »
R&D pertaining to the tools needed to advance nanotechnology research and commercialization, including next-generation instrumentation for characterization, measurement, synthesis, and design of… »
Issue associated with device or device parts being insufficiently cool in device active (working) or/and non-active (non-working) state. The concept does not… »
Issue associated with an underdose of intravenous therapy, i.e., drugs or fluids being delivered into a patient under positive pressure generated by… »
An invaginated portion of the cerebral cortex forming the base of the sylvian fissure. It is part of the lateral side… »
A material designed to reduce the transmission of heat, sound, or electricity. »
A hormone made by the islet cells of the pancreas. Insulin controls the amount of sugar in the blood by moving it… »
A recombinant human insulin analog with rapid-acting, blood glucose-lowering activity. Insulin aspart, acting faster than regular human insulin, regulates glucose metabolism by… »
A drug used to control the amount of sugar in the blood of patients with diabetes. It is a form of the… »
A drug used to control the amount of sugar in the blood of patients with diabetes. It is a form of the… »
A drug used to control the amount of sugar in the blood of patients with diabetes mellitus. It is a form of… »
The determination of the amount of insulin-like growth factor-1 present in a sample. »
The determination of the amount of insulin-like growth factor-2 present in a sample. »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous human insulin. In lispro insulin, the amino acid… »
The determination of the amount of insulin present in a sample. »
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction… »
Insulin receptor substrate 1 (1242 aa, ~132 kDa) is encoded by the human IRS1 gene. This protein is involved in insulin-mediated… »
Insulin receptor substrate 2 (1338 aa, ~137 kDa) is encoded by the human IRS2 gene. This protein is involved in insulin-dependent signal… »
Similar in function to IRS1 and IRS2; insulin receptor substrate 4 is a cytoplasmic protein that contains many potential tyrosine and serine/threonine… »
Encoded by human INSRR Gene (Insulin Receptor Family), 1297-aa 144-kDa (precursor) Insulin Receptor-Related Receptor is a type I membrane protein containing 4… »
Decreased sensitivity to circulating insulin which may result in acanthosis nigicrans, elevated insulin level or hyperglycemia. »
The insulin resistance of type II diabetes appears to be caused in part by the presence of high levels of lipids in… »
A cluster of closely related metabolic abnormalities associated with insulin resistance that confer an increased risk of the development of type 2… »
A hypoglycemic reaction to overdosage of insulin, a skipped meal, or strenuous exercise in an insulin-dependent diabetic. »
The appropriate signaling through the insulin pathway is critical for the regulation of glucose levels and the avoidance of diabetes. Insulin forms… »
Insulin-degrading enzyme (1019 aa, ~118 kDa) is encoded by the human IDE gene. This protein is involved in the metabolism of bioactive… »
A protein made by the body that stimulates the growth of many types of cells. Insulin-like growth factor is similar to insulin… »
Elevated serum levels of insulin-like growth factor-1 (IGF-1) may identify premenopausal women who are likely to develop breast cancer before age… »
Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell… »
Insulin-like growth factors I and II, also known as somatomedin C and somatomedin A, respectively, are single chain polypeptides which share an… »
Insulin-like growth factor binding protein 1 (259 aa, 28 kD) is a cell communication protein that is encoded by the human IGFBP1… »
The determination of the amount of insulin-like growth factor binding protein 3 present in a sample. »
Insulin-like growth factor binding protein 4 (258 aa, 28 kD) is a cellular division process protein that is encoded by the human… »
A protein found on the surface of some types of cells that binds to insulin-like growth factor (IGF). This causes the cells… »
A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. Serum IGFBP… »
Encoded by human IGFBP2 Gene, cysteine-rich high molecular weight secreted 328-aa 35-kD Insulin-Like Growth Factor-Binding Protein 2 precursor contains an IGFBP domain… »
Insulin-like growth factor-binding protein 3 (291 aa, 32 kD) is a cell fate protein that is encoded by the human IGFBP3 gene… »
IGFBP5 contains a thyroglobulin type-I domain and belongs to the IGFBP family. IGFBPs display strong sequence homologies. IGFBPs contain three… »
Insulin-like growth factor binding protein 6 (240 aa, 25 kD) is a cellular division process protein that is encoded by the human… »
Insulin-like growth factor binding protein 7 (282 aa, ~29 kDa) is encoded by the human IGFBP7 gene. This protein may play a… »
A product of the NOV gene. It is a member of the CCN family of proteins, expressed after induction by growth… »
Expressed in fetal perichondrium, uterus, cytotrophoblasts, and syncytiotrophoblasts as a 139-aa 15-kDa precursor by human INSL4 Gene (Insulin Family), Insulin-Like Peptide 4… »
A mixture of two types of insulin consisting of 70 percent long-acting insulin suspension and 30 percent rapid-acting insulin. Typically administered… »
A long-acting crystalline insulin often used in combination with a short-acting insulin in the treatment of diabetes mellitus. This type of… »
An intermediate-acting insulin used in the treatment of diabetes mellitus. Administered once or twice daily, NPH (neutral protamine hagedorn) insulin lowers… »
A short-acting form of insulin. Regular insulin is obtained from animal or recombinant sources. The onset of action of regular… »
A long-acting form of crystalline insulin often used in combination with a short-acting insulin in the treatment of diabetes mellitus. Administered… »
Insulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase… »
An abnormal mass that grows in the beta cells of the pancreas that make insulin. Insulinomas are usually benign (not cancer). They… »
A mechanism for guarding against financial aspects of risk by making payments in the form of premiums to an insurance company, which… »
The effect of insurance coverage on medical care and practices. »
Payment by a third-party payer in a sum equal to the amount expended by a health care provider or facility for health… »
The determination of the amount of the intact (containing amino acids 1-42) glucose-dependent insulinotropic peptide present in a sample. »
The determination of the amount of intact parathyroid hormone present in a sample. »
The process of taking in a substance, especially by eating or drinking, or the quantities thereof; admittance of people to a place… »
A number with no fractional part, including the negative and positive numbers as well as zero. »
A data type comprised of numbers with no fractional part, including the negative and positive numbers as well as zero. »
A data type comprised of an integer divided by a physical quantity expressed in units of time. »
Integrase is an enzyme that catalyzes the integration of viral DNA into the host genome. These enzymes act to cleave and religate… »
A microelectronic device that incorporates many interconnected transistors and components. »
A device that uses only integrated circuits. »
An assessment used to indicate a person's overall level of fitness, including tests used to assess a person's muscle strength, endurance, and… »
A computer system that provides tutorial instruction in academic subjects at an individual level in a format that allows students to master… »
A group formed in 1993 by four academic groups on a collaborative basis after informal discussions led to a common vision of… »
An instrument designed to take into account both pain intensity and duration. (Ventafridda 1983) »
An operation used in calculus whereby the integral of a function is determined. »
Location of the integration of the engineered gene e.g. random or targeted. »
A type of medical care that combines conventional (standard) medical treatment with complementary and alternative (CAM) therapies that have been shown to… »
Integrator complex subunit 6 (887 aa, ~100 kDa) is encoded by the human INTS6 gene. This protein is involved in the synthesis… »
Integrins are transmembrane glycoprotein receptors that mediate cell-matrix or cell-cell adhesion, and transduce signals that regulate gene expression and cell growth. … »
Integrin alpha 5 (1049 aa, 115 kD) is a cell adhesion process protein that is encoded by the human ITGA5 gene and… »
Integrin alpha M (1152 aa, 127 kD) is a cell adhesion process protein that is encoded by the human ITGAM gene and… »
Integrin alpha V (1148 aa, 116 kD) is a cell adhesion process protein that is encoded by the human ITGAV gene and… »
Leukocyte Surface Antigen p150,95 has a unique alpha chain (CD11c) and shares a beta subunit (CD18) with two other members of the… »
Integrin alpha-4 (1032 aa, ~115 kDa) is encoded by the human ITGA4 gene. This protein is involved in the mediation of both… »
Integrin alpha-E (1179 aa, ~130 kDa) is encoded by the human ITGAE gene. This protein plays a role in cell adhesion and… »
Integrin alpha-IIb (1039 aa, ~113 kDa) is encoded by the human ITGA2B gene. This protein is involved in the mediation of platelet… »
Integrin alpha-IIb/beta3 is a protein complex comprised of a heterodimer of integrin alpha 2b and integrin beta 3. This complex is involved… »
Integrin alpha-L (1170 aa, 129 kD) is a cell motility process protein that is encoded by the human ITGAL gene and has… »
Integrin alpha4/beta1 is a protein complex comprised of a heterodimer of integrin alpha4 and integrin beta1. This complex plays a role in… »
Integrin alphaL/beta2 is a protein complex comprised of a heterodimer of integrin alphaL and integrin beta2. This complex is involved in leukocyte… »
Integrin alpha-M/beta2 is a protein complex comprised of a heterodimer of integrin alpha M and integrin beta 2. This complex is involved… »
Involved in cell adhesion and signaling, human Integrin-aVBeta3 is composed of type I membrane protein chains Integrin Alpha V (disulfide-linked heavy and… »
Integrin alpha-V beta-5 is a heterodimeric protein with subunits designated alpha-V and beta-5. This complex is involved in both cellular adhesion, cell… »
Integrin beta-1 (798 aa, ~88 kDa) is encoded by the human ITGB1 gene. This protein plays a role in leukocyte migration, signal… »
Integrin beta-2 (769 aa, 85 kD) is a cell motility process protein that is encoded by the human ITGB2 gene and has… »
Integrin beta-3 (788 aa, 87 kD) is a cell adhesion process protein that is encoded by the human ITGB3 gene and has… »
Integrin beta-4 (1822 aa, 202 kD) is a cell adhesion process protein that is encoded by the human ITGB4 gene and has… »
Integrin beta-5 (799 aa, ~88 kDa) is encoded by the human ITGB5 gene. This type I membrane protein forms a heterodimer with… »
Integrin beta-7 (798 aa, ~87 kDa) is encoded by the human ITGB7 gene. This protein plays a role in both cell adhesion… »
A process that involves the binding of an integrin to one of its ligands, including fibronectin, vitronectin, collagen and laminin. These interactions… »
Integrin Inhibition involves interference with, or restraint of, the activities of a family of noncovalent heterodimeric transmembrane glycoprotein signal transduction receptors for… »
A small molecule integrin receptor antagonist (IRA) with potential antineoplastic activity. Upon administration, GLPG0187 binds to and blocks the activity of 5… »
Integrins are cell surface receptors that interact with the extracellular matrix and mediate intracellular signals in response to the extracellular matrix including… »
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with… »
The enveloping membrane of the body; includes, in addition to the epidermis and dermis, all of the derivatives of the epidermis, e.g.,… »
Symptoms, physical examination results, and/or laboratory test results related to the integumentary system. »
A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to integumentary system findings. … »
Any component of the enveloping membrane of the body, including the epidermis and dermis, and all of the derivatives of the… »
Patient complaints (symptoms), physical and/or laboratory findings related to the skin or integument. »
Surgery on the skin (integument). »
A broad category of disorders characterized by an impairment to the intelligence an individual possesses. These impairments can result from trauma, birth… »
Creations of the mind, such as those created by musicians, authors, artists, and inventors. »
The legal permission to use the work of an individual's original creation, such as trademarks, copyrights, patents, proprietary technologies and images. … »
A powerful, temporary tensing of the uterine muscles that is stronger than previously felt movements. »
Treatment that is given after cancer has disappeared following the initial therapy. Intensification therapy is used to kill any cancer cells that… »
A type of 3-dimensional radiation therapy that uses computer-generated images to show the size and shape of the tumor. Thin beams of… »
A health care facility unit that provides intensive care to critically ill patients and patients with complex medical problems who require constant… »
The first 8 weeks of treatment for tuberculosis during which the infection is treated aggressively with multiple drugs. »
The use of a particular medical device, medication or treatment to help establish the presence or absence of a disease or… »
The use of a particular medical device, medication or treatment to help minimize the effects of a disease or condition. »
The use of a particular medical device, medication or treatment to help reduce the risk of contracting or developing a disease or… »
A compounder intends to produce a drug classified as 506E. »
The use of a particular medical device, medication or treatment to treat a pre-existing disease or condition. »
The therapeutic blockage of the muscular pouch in the left atrium. »
An injury that is not the result of an accident or natural causes. »
The extent to which two different researchers obtain the same result when using the same instrument to measure a concept. »
The quality, state, or process of (two or more things) acting on each other. »
A clinical term that indicates the presence of a white mucosal patch in the interarytenoid area. In most cases histologic examination… »
The tissue that separates the right atrium from the left atrium in the heart. »
The intercalated cell is an epithelial cell of the renal collecting tubule that is specialized for H+ and HCO3 transport. These cells… »
The intercellular structures including the fascia adherens, gap junctions and macula adherens that connect single cardiac muscle cells to allow for synchronized… »
One of two types of intercalated ducts located in either the pancreas or salivary gland. »
The tiny tubules with a very thin epithelial layer in the pancreas running from the pancreatic acini into the striated duct. … »
The tiny tubules with a very thin epithelial layer in the salivary glands running from the salivary acini into the striated… »
In biochemistry, a type of molecule that binds to DNA and inserts itself into the DNA structure. Some intercalators are used as… »
LFA-1 is a receptor for ICAM1, a surface molecule constitutively expressed on some tissues and induced on others in inflammation. The… »
CD102. Intracellular Adhesion Molecule-2. »
ICAM3 is a ligand for LFA-1, a major receptor of T-cells, B-cells, and granulocytes that mediates the leukocyte adhesion reactions underlying many… »
The transfer of information from one cell to another. Cells signal each other by direct contact with each other or by the… »
Intercellular Communication Induction involves initiation of activities of biologic molecules, biologic complexes, or subcellular components involved in the transmission of signals between… »
Intercellular Communication Inhibition involves interference with, or restraint of, the activities of biologic molecules, biologic complexes, or subcellular components involved in the… »
Any process by which signals are passed from one cell to another through a direct multicellular interaction. This process is involved widely… »
Intercellular Signaling Alteration involves a change in the quality of the existing state of communication between cells, whether by direct cell contact… »
Any cellular process involved in translocation of substances into or out of a cell. »
Develop, evaluate, and implement strategies for interrupting vertical transmission of HIV from mother to child and extend our understanding of perinatal transmission… »
Orthodontic treatment designed to take advantage of the active growth stage of a child's development in order to intercept orthodontic problems early… »
A communications device designed for use between rooms of a building. »
The nine paired arteries arising from the aorta that supply the intercostal spaces (area between the ribs). »
Either of three arteries (posterior or dorsal branch, collateral intercostal and spinal) that branch off of the intercostal artery. »
A lymph node located in the intercostal space of the thoracic wall. »
A muscle located between two ribs. »
The anterior primary branches of the thoracic spinal nerves (T1 to T11). »
The marked inward movement of the muscles between the ribs during inhalation; they indicate that there is reduced pressure in the chest… »
The space between the digits of the hand or foot. »
A dendritic cell found in the paracortex that captures blood-borne antigens in peripheral tissues and transports them to the periarteriolar lymphoid sheath… »
A neoplastic proliferation of spindle to ovoid cells which show phenotypic features similar to those of interdigitating dendritic cells. The clinical… »
Studies that bring together multiple scientific disciplines to address specific issues. »
Collaborative and interdisciplinary genetic epidemiology investigations designed to identify and evaluate the interactions of genetic and epidemiologic risk factors leading to cancer… »
A question about whether an individual is or was interested in sex. »
Either a program that controls a display for the user and that allows the user to interact with the system or a… »
Phenomena originating at the interface of material. »
The act of hindering or obstructing or impeding. »
A question about whether an individual's physical condition or medical treatment interferes or has interfered with their family life. »
The act of impeding a person from their normal social activities. »
A question about whether an individual's physical condition or medical treatment interferes or has interfered with their social activities. »
An unpleasant memory or idea that occurs often in a person’s everyday thoughts and keeps him or her from thinking about other… »
A biological response modifier (a substance that can improve the body's natural response to infections and other diseases). Interferons interfere with the… »
A drug used to treat AIDS-related Kaposi sarcoma in certain patients, hairy cell leukemia, and melanoma that has been removed by… »
A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at… »
A formulated therapeutic analog of the endogenous alpha interferon containing multiple interferon species with antiviral and antitumor properties. Interferons bind to… »
An analogue of consensus interferon which contains an additional methionyl amino acid residue. Consensus interferon (also known as interferon alfacon-1, rCon-IFN,… »
A class of interferon (leukocyte interferon) produced predominantly by B lymphocytes. Located in a cluster on 9p22 there are at least… »
Encoded by human IFNA13 Gene (IFN Alpha Family) and expressed by macrophages, secreted 189-amino acid 21.7 kD (precursor) Interferon Alpha 13 contains… »
Encoded by human INFA2 Gene (IFN Alpha Family) and expressed by macrophages, secreted 188-amino acid 21.6 kD (precursor) Interferon Alpha 2 contains… »
The determination of the amount of interferon alpha present in a sample. »
Human Interferon Alpha Receptor Complex (Type II Cytokine Family Receptor) is a ubiquitous type I membrane protein heteromeric receptor for type I… »
IFN alpha-beta receptor beta chain (515 aa, 58 kD) is a cell communication process protein that is encoded by the human IFNAR1… »
IFN alpha-beta receptor alpha chain (557 aa, 64 kD) is a cell communication protein that is encoded by the human IFNAR1 gene… »
A class of interferon elaborated by fibroblasts. »
The determination of the amount of interferon beta present in a sample. »
A synthetic version of naturally occuring interferons that have immunomodulatory, antiviral and antiproliferative activities. It may exert antitumor activity by anti-angiogenic and… »
A recombinant form of the natural Interferon beta that varies in the amino acid sequence and lacks the carbohydrate side chain. Clinical… »
Interferon gamma (IFNg) is produced by activated T cells and is an important immunoregulatory molecule, particularly in allergic diseases. »
The determination of the amount of interferon gamma present in a sample. »
Encoded by human IFNGR2 Gene (Type II Cytokine Receptor Family), 337-aa 38-kDa (precursor) type I membrane protein Interferon Gamma Receptor Beta Chain… »
Expressed in monocytes, lymphocytes, and placenta, human Interferon Gamma Receptor Complex (Type II Cytokine Family Receptor) is a Ser/Thr phosphorylated type I… »
Interleukin-29 (200 aa, ~22 kDa) is encoded by the human IFNL1 gene. This protein plays a role in both cytokine signaling and… »
Interleukin-28A (200 aa, ~22 kDa) is encoded by the human IFNL2 gene. This protein is involved in both cytokine-mediated signaling and antiviral… »
Interferon lambda-3 (196 aa, ~22 kDa) is encoded by the human IFNL3 gene. This protein plays a role in cytokine signaling. … »
The determination of the amount of interferon present in a sample. »
Encoded by human IFNW1 Gene (IFN Alpha, Beta, Delta Family), secreted 195-amino acid 22 kD (precursor) Interferon Omega 1, a type I… »
Interferon regulatory factor 1 (325 aa, ~37 kDa) is encoded by the human 325 gene. This protein plays a role in the… »
Interferon regulatory factor 2 (349 aa, ~39 kDa) is encoded by the human IRF2 gene. This protein is involved in the modulation… »
Interferon regulatory factor 2-binding protein 2 (587 aa, ~61 kDa) is encoded by the human IRF2BP2 gene. This protein plays a role… »
Interferon regulatory factor 3 (427 aa, ~47 kDa) is encoded by the human IRF3 gene. This protein plays a role in the… »
Interferon regulatory factor 4 (451 aa, ~52 kDa) is encoded by the human IRF4 gene. This protein is involved in the mediation… »
Interferon regulatory factor 6 (467 aa, ~53 kDa) is encoded by the human IRF6 gene. This protein plays a role in the… »
Interferon regulatory factor 8 (426 aa, ~48 kDa) is encoded by the human IRF8 gene. This protein plays a role in the… »
Interferon regulatory factor 9 (393 aa, ~44 kDa) is encoded by the human IRF9 gene. This protein plays a role in activating… »
Signaling by interferon-gamma stimulates anti-viral responses and tumor suppression through the heterodimeric interferon-gamma receptor. Signaling is initiated by binding of interferon-gamma… »
Any process which promotes expression of the interferon proteins, their subsequent secretion, binding to cognate receptors or intracellular signaling, and promotes antigen… »
Any therapeutic or preventive precedure that involves inhibition of the production or activity of an interferon. This process may result also in… »
A member of the alpha-chemokine family, IP10 is secreted from macrophages, endothelial cells, and keratinocytes in response to IFN-gamma and activates a… »
Interferon-induced GTP-binding protein Mx1 (662 aa, ~76 kDa) is encoded by the human MX1 gene. This protein plays a role in GTP… »
Interferon-induced GTP-binding protein Mx2 (715 aa, ~82 kDa) is encoded by the human MX2 gene. This protein plays a role in both… »
Encoded by human IFITM1 Gene (IFN-Induced Transmembrane Protein Family), 125-amino acid 14-kD Interferon-Induced Transmembrane Protein 1 is an IFN-alpha- and -gamma-inducible membrane… »
Interferon-induced, double-stranded RNA-activated protein kinase (551 aa, ~62 kDa) is encoded by the human EIF2AK2 gene. This protein is involved in both… »
Interferon-inducible protein AIM2 (343 aa, ~39 kDa) is encoded by the human AIM2 gene. This protein may be involved in apoptosis, inflammation… »
Single Nucleotide Polymorphism in Intergenic Sequences consists of a variation at an appreciable frequency between individuals of a single interbreeding population of… »
The planned duration from the start of dosing to the interim sacrifice of the subject. »
Involving cooperation between labs. »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukins regulate immune… »
The determination of the amount of interleukin 1 beta present in a sample. »
The determination of the amount of interleukin 1 present in a sample. »
The determination of the amount of interleukin 1 receptor antagonist present in a sample. »
The determination of the amount of interleukin 10 present in a sample. »
Interleukin-10 Receptor Beta Chain (325 aa, 37 kD) is a cell motility protein that is encoded by the human IL10RB gene and… »
The determination of the amount of interleukin 11 present in a sample. »
This protein is the alpha subunit of the high-affinity receptor for interleukin-11. This particular receptor is very similar to ciliary neurotrophic factor,… »
The determination of the amount of interleukin 12 present in a sample. »
Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2… »
Human high affinity Interleukin 12 Receptor Beta (Type I Cytokine Receptor 2 Family) is composed of Interleukin 12 Receptor Beta 1 Chain… »
The determination of the amount of interleukin 13 present in a sample. »
The determination of the amount of interleukin 14 present in a sample. »
The determination of the amount of interleukin 15 present in a sample. »
The determination of the amount of interleukin 16 present in a sample. »
The determination of the amount of interleukin 17 present in a sample. »
The determination of the amount of interleukin 18 present in a sample. »
The determination of the amount of interleukin 19 present in a sample. »
The determination of the amount of interleukin 2 present in a sample. »
The interleukin 2 (IL2) receptor gamma chain (IL2RG) is an important signalling component of many interleukin receptors (e.g., IL2,IL4,IL7,IL9, and IL15) and… »
The determination of the amount of interleukin 20 present in a sample. »
The determination of the amount of interleukin 21 present in a sample. »
The determination of the amount of interleukin 22 present in a sample. »
The determination of the amount of interleukin 23 present in a sample. »
The determination of the amount of interleukin 24 present in a sample. »
The determination of the amount of interleukin 25 present in a sample. »
The determination of the amount of interleukin 26 present in a sample. »
The determination of the amount of interleukin 27 present in a sample. »
The determination of the amount of interleukin 28 present in a sample. »
The determination of the amount of interleukin 29 present in a sample. »
The determination of the amount of interleukin 3 present in a sample. »
Heterodimeric human Interleukin 3 Receptor is composed of 378-aa 43-kDa (precursor) Interleukin 3 Receptor Alpha and GM-CSF/IL-3/IL-5 Receptor Common Beta-Chain. IL3RA is… »
Encoded by human IL3RA Gene (Type I Cytokine Receptor 5 Family), 378-aa 43-kDa (precursor) Interleukin 3 Receptor Alpha is a type I… »
The determination of the amount of interleukin 30 present in a sample. »
The determination of the amount of interleukin 31 present in a sample. »
The determination of the amount of interleukin 32 present in a sample. »
The determination of the amount of interleukin 33 present in a sample. »
The determination of the amount of interleukin 4 present in a sample. »
IL4R when complexed with the common gamma chain (IL2RG) serves as the high-affinity interleukin 4 (IL4) receptor. It plays a major role… »
The determination of the amount of interleukin 5 present in a sample. »
The determination of the amount of interleukin 6 present in a sample. »
Widely expressed (not restricted to IL6 responsive cells) by human IL6ST Gene (Type I Cytokine Receptor 2 Family), heterodimeric type I membrane… »
The determination of the amount of interleukin 7 present in a sample. »
The determination of the amount of interleukin 8 present in a sample. »
High Affinity Interleukin-8 Receptor A (350 aa, 40 kD) is a cell motility protein that is encoded by the human IL8RA gene… »
Interleukin-8 is a member of a family of pro-inflammatory cytokines. The best-characterized activities of IL8 include the chemoattraction and activation of… »
The determination of the amount of interleukin 9 present in a sample. »
Interleukin Genes encode Interleukins, soluble cytokine factors produced by leukocytes and other cell types that have broad functional activities, particularly in regulating… »
Any process which promotes expression of the interleukin proteins, their secretion, receptor binding or intracellular signaling, and promotes proliferation and differentiation among… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-1 is made… »
Interleukin-1 beta (269 aa, ~31 kDa) is encoded by the human IL1B gene. This protein is involved in the macrophage-dependent inflammatory… »
Encoded by human IL1R1 Gene (IL1R Family), 569-aa 65-kDa (precursor) Interleukin-1 Receptor Alpha Type I is a type I membrane protein cytokine… »
Interleukin-1 receptor antagonist protein (177 aa, ~20 kDa) is encoded by the human IL1RN gene. This protein is involved in the inhibition… »
Encoded by human IL1R2 Gene (IL1R Family), 398-aa 45-kDa (precursor) Interleukin 1 Receptor Beta Type II is a type I membrane protein… »
Interleukin-1 receptor-associated kinase 1 (712 aa, ~77 kDa) is encoded by the human IRAK1 gene. This protein plays a role in protein… »
Expressed in peripheral leukocytes and monocytes by human IRAK3 Gene, 596-aa Interleukin-1 Receptor-Associated Kinase 3 contains an N-terminal death domain and central… »
Widely expressed (strongest in kidney and liver) by human IRAK4 Gene, 460-aa Interleukin-1 Receptor-Associated Kinase 4 contains (like IRAK1, IRAK2, IRAKM, and… »
Interleukin-1 receptor-associated kinase-like 2 (625 aa, ~70 kDa) is encoded by the human IRAK2 gene. This protein is involved in signaling. … »
Interleukin-1 receptor-like 1 (556 aa, ~63 kDa) is encoded by the human IL1RL1 gene. This protein plays a role in binding interleukin-33… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-1-alfa, one form… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-1-alpha, one form… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-1-beta, one form… »
An aqueous therapeutic analogue of the endogenous cytokine interleukin-1-beta (IL-1-beta). Produced mainly by monocytes, endogenous IL-1-beta plays a role in hematopoiesis, is… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-10 is made… »
Interleukin-10 receptor subunit alpha (578 aa, ~63 kDa) is encoded by the human IL10RA gene. This protein plays a role in the… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-11 is made… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-12 is made… »
The DNA sequence that encodes the protein cytokine interleukin-12 (IL-12). When introduced as the complementary DNA (cDNA) form into tumor cells by,… »
Interleukin-12 receptor subunit beta-1 (662 aa, ~73 kDa) is encoded by the human IL12RB1 gene. This protein plays a role in interleukin-12… »
Interleukin-12 receptor subunit beta-2 (862 aa, ~97 kDa) is encoded by the human IL12RB2 gene. This protein is involved in the modulation… »
Interleukin-12 subunit alpha (219 aa, ~25 kDa) is encoded by the human IL12A gene. This protein plays a role in cytokine signaling… »
Interleukin-12 subunit beta (328 aa, ~37 kDa) is encoded by the human IL12B gene. This protein is involved in the growth of… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-13 is made… »
A substance being studied in the treatment of cancer. It is made by combining interleukin-13 with a toxin from Pseudomonas bacteria. It… »
IL13 receptor alpha 1 protein (427 aa, 49 kD) is a cell communication process protein that is encoded by the human IL13RA1… »
Interleukin-13 receptor subunit alpha-2 (380 aa, ~44 kDa) is encoded by the human IL13RA2 gene. This protein plays a role in both… »
Interleukin-14, encoded by the IL14 gene, is a cytokine that induces B-cell proliferation, inhibits immunoglobulin secretion, and selectively expands certain B-cell… »
Interleukin-15, encoded by the IL15 gene, is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and… »
Interleukin-16, encoded by the IL16 gene, is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and… »
Interleukin 17 is a homodimer expressed in stimulated, but not resting, cytotoxic T-cells that induces stromal cells to produce pro-inflammatory and hematopoietic… »
Interleukin-17 receptor B (502 aa, ~56 kDa) is encoded by the human IL17RB gene. This protein plays a role in both cytokine… »
Expressed in activated T cells by human IL17C Gene (IL-17 Family), 197-aa 22-kDa (precursor) secreted cytokine Interleukin-17C (IL17-related) may stimulate release of… »
Cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK cells and CTLs, and appears to play… »
Interleukin-19, encoded by the IL19 gene, is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-2 is made… »
A vaccine based on anti-idiotype (Id) monoclonal antibodies combined with interleukin-2 (IL-2). Anti-Id vaccines have been shown to be effective in… »
The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by,… »
A glycoprotein cytokine produced by the human leukemia T-cell line Jurkat. As a paracrine factor, IL-2 drives the expansion of antigen- specific… »
A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T-lymphocytes, such as lymphokine-activated killer cells, and… »
A heterotrimeric protein found on the cell surface of immune cells that binds to interleukin-2. This receptor is comprised of alpha, beta… »
Interleukin-2 receptor alpha chain (272 aa, 31 kD) is a cell fate protein that is encoded by the human IL2RA gene and… »
Interleukin-20 (176 aa, ~20 kDa) is encoded by the human IL20 gene. This protein is involved in the regulation of signal transducer… »
Interleukin-21 (155 aa, ~18 kDa) is encoded by the human IL21 gene. This protein plays a role in both receptor-mediated signaling and… »
Interleukin-21 receptor protein (538 aa, ~59 kDa) is encoded by the human IL21R gene. This protein plays a role in both the… »
Interleukin-22 (179 aa, ~20 kDa) is encoded by the human IL22 gene. This protein is involved in both cell signaling and the… »
Interleukin 23, alpha subunit p19 protein (189 aa, ~21 kDa) is encoded by the human IL23A gene. This protein plays a role… »
Encoded by human IL24 Gene, secreted Interleukin 24 Protein (IL10 Family) consists of 206 amino acids with a predicted size of 23.8… »
Interleukin-25 (177 aa, ~20 kDa) is encoded by the human IL25 gene. This protein is involved in the regulation of inflammation. … »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-3 is made… »
Interleukin-33 (270 aa, ~31 kDa) is encoded by the human IL33 gene. This protein plays a role in the positive regulation of… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-4 is made… »
A substance being studied in the treatment of cancer. It is made by combining interleukin-4 with a bacterial toxin. Interleukin-4 PE38KDEL cytotoxin… »
A substance being studied in the treatment of cancer. It is made by combining interleukin-4 with a bacterial toxin. Interleukin-4 PE38KDEL immunotoxin… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-5 is made… »
Interleukin-5 receptor subunit alpha (420 aa, 48 kD) is a cell division process protein that is encoded by the human IL5RA gene… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-6 is made… »
Interleukin-6 receptor subunit alpha (468 aa, 52 kD) is a cell division process protein that is encoded by the human IL6R gene… »
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-7 is made… »
Interleukin-7 receptor subunit alpha (459 aa, ~52 kDa) is encoded by the human IL7R gene. This protein is involved in both interleukin… »
A member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is… »
A family of chemokine receptors that specifically bind to interleukin-8 and play a role in G-protein-coupled receptor-mediated signal transduction. »
Human interleukin-9 protein (144 aa 16 kDa precursor) is encoded by the human interleukin-9 (IL9) gene. This glycoprotein is secreted by T-cells… »
An artery that supplies blood to the renal lobes. »
A gland duct that drains secretions from more than one lobe of an organ. »
The condition existing when an order or judgement is considered temporary until either a specified period of time has passed or specific… »
Any relationship between the upper and lower jaws. »
All the reactions in an organism concerned with storing and generating metabolic energy and with the biosynthesis of low-molecular weight compounds, energy-storage… »
An inborn metabolic disorder affecting the intermediary metabolism process. It results in accumulation of substances in the body that can cause acute… »
Lying between two extremes in time or space or degree. »
A borderline blood vessel neoplasm that has locally aggressive behavior. »
A borderline blood vessel neoplasm that may metastasize on rare occasions. »
A borderline blood vessel neoplasm that can be locally aggressive, and may metastasize on rare occasions. »
A medical center that provides care 24 hours per day. »
The likelihood an individual will develop coronary artery disease (CAD) is moderate or between 10% and 90%. (Gibbons RJ, Balady GJ, Bricker… »
A borderline fibrohistiocytic neoplasm arising from the dermis and extending to the subcutaneous tissues. »
The determination of the amount of intermediate density lipoprotein present in a sample. »
A Sertoli-Leydig cell tumor of the ovary characterized by the presence of spindle-shaped gonadal stromal cells and Sertoli cells, some of which… »
An ovarian Sertoli-Leydig cell tumor of intermediate differentiation, characterized by the presence of a heterologous component, usually consisting of cartilage, skeletal muscle,… »
A type of striated skeletal muscle fiber that contracts quicker than a red fiber but slower than a white fiber and contains… »
A neoplasm of borderline malignant potential that arises from the soft tissues. It is characterized by the presence of spindle-shaped… »
A fibrohistiocytic neoplasm usually affecting younger patients. It is characterized by an increased risk of local recurrence and a low risk… »
A class of tough protein filaments (including keratin filaments, neurofilaments, desmin, and vimentin) that measure 8-10 nm in thickness and comprise part… »
Intermediate Filament Genes encode a number of different Intermediate Filament Proteins (including keratin filaments, neurofilaments, desmin, and vimentin) that form polymeric structural… »
Encoded by Intermediate Filament Genes, diverse Intermediate Filament Proteins (including keratin filaments, neurofilaments, desmin, and vimentin) form polymeric structural cytoplasmic filaments, intermediate… »
A term used to describe how abnormal cancer cells look under a microscope. Intermediate-grade cancer cells look more abnormal than low-grade cancer… »
Ductal breast carcinoma in situ characterized by the presence of monomorphic neoplastic cells that form cribriform, micropapillary, or solid patterns. Intraluminal necrosis… »
An intermediate grade malignant neoplasm with neuroendocrine differentiation that arises from the lung. This category includes atypical carcinoid tumor. »
A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma and high-grade lymphoma. »
A salivary gland mucoepidermoid carcinoma with intermediate grade histopathologic features. »
An immature teratoma characterized by the presence of an intermediate amount of undifferentiated tissues. »
The likelihood an individual will develop ischemia is moderate. »
A lipomatous neoplasm characterized by a high risk of local recurrence and no risk of metastasis. »
A morphologic variant of fetal rhabdomyoma characterized by the presence of spindle cell myoblasts and strap-like skeletal muscle cells. »
The potential future harm that may arise from some present action or attribute or condition is moderate. »
A soft tissue neoplasm arising from mesenchymal cells. It is characterized by an increased risk of local recurrence and a low… »
A trophoblast that travels into the junctional zone of the decidua, reacting with maternal tissue leukocytes, mainly NK cells, macrophages and T… »
Inflammation of the pars plana, ciliary body, and adjacent structures. »
A vascular neoplasm with borderline malignant potential. »
A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma and high-grade lymphoma. »
The space between the outer membrane and the inner membrane of the mitochondrion. »
Periodically stopping and starting. »
Issue associated with the ineffective and inconsistent depolarization of the heart. »
A disorder characterized by recurrent episodes of serious assaultive acts or destruction of property due to a failure to resist aggressive impulses;… »
Fetal heart rate decelerations that occur with less than 50 percent of uterine contractions within a 20 minute timeframe. »
Issue associated with the failure of pacing device for a limited period of time, following which the item recovers its ability to… »
Issue associated with the failure to deliver shock for a limited period of time, following which the item recovers its ability to… »
An opening in the transversalis fascia midway between the anterior superior iliac spine and pubic tubercle through which the spermatic cord (males)… »
A ring of smooth muscle surrounding the anus on the inside of the external anal sphincter. »
A blood vessel branching from the basilar artery that runs along the auditory nerve to supply the inner ear. »
A canal in the petrous region of the temporal bone that serves as the passage for cranial nerves (mainly the VII and… »
A meningioma that affects the internal auditory canal. »
One of many blood vessels arising from the posterior tibial artery supplying the fat and integument of the heel and Achilles tendon… »
White matter pathway, flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the cerebral cortex and the… »
An artery arising from the bifurcation of the common carotid artery on each side of the body at the level of the… »
Any artery arising from the internal carotid artery. »
A series of autonomic nerves around the internal carotid artery. »
A pair of parallel blood vessels deep within both cerebral hemispheres that are formed by the union of the choroid and terminal… »
A blood vessel arising from the profunda artery with one branch supplying the hip joint and two other branches supplying the adductor… »
The extent to which all items in a scale or test measure the same concept. »
The first or medial wedge-shaped bone in the distal row of the tarsus. »
A stretchable connective tissue membrane that is the outermost component of the tunica intima, delineating the border between the tunica media and… »
A physical exam of the vagina, cervix, uterus, fallopian tubes, ovaries, and rectum. First, the area outside the vagina is checked for… »
A finding during labor, in which the occiput rotates anteriorly and the head of the fetus assumes an oblique orientation while the… »
The medial one of a pair of small masses that protrude from the posteroinferior part of the thalamus; commonly considered a part… »
The fourth layer of the cerebral cortex, composed of many densely packed granule cells with short axons and some small pyramidal cells,… »
A hemorrhoid which originates above the dentate line. »
A short thick blood vessel arising from the bifurcation of the common iliac artery with numerous branches that supply the organs, walls… »
Any artery arising from the internal iliac artery. »
A lymph node located along the internal iliac artery. »
A blood vessel running parallel to the internal iliac artery that joins with the external iliac vein to drain blood into the… »
A continuation of the sigmoid sinus of the dura mater; joins the subclavian vein to form the brachiocephalic vein. »
A flat, triangular fibrous tissue connected to the inner malleolus, navicular bone and ligament, os calcis and astragalus. »
The space bounded by the nine microtubule triplets of the centriole. »
A blood vessel arising from the anterior tibial artery that runs along the medial side of the ankle to supply the ankle… »
The blood vessel that supplies the breast and the anterior chest wall with arterial blood. It is located in the chest… »
Any of the lymph nodes of the breast located under the ribcage, near the sternum. »
A medical specialty concerned with the diagnosis of diseases of the internal organs and non-surgical treatments. »
The inner portion of the nostrils of the nose. »
A large thin muscle beneath the external oblique that stretches from the iliac crest to the inferior borders of the tenth to… »
A group of veins that drain the infero-internal portion of the occipital lobe into the vein of Galen. »
The longer vertical portion of the parieto-occipital fissure, a deep groove, on the medial surface of the cerebral cortex extending from the… »
An artery that runs along the inside of the foot supplying those muscles as well as the toes. »
A powder intended for use within the body. »
A quadrilateral muscle extending from the lateral pterygoid plate to the medial surface of the mandible that closes the jaw and aids… »
An artery that supplies the external sex organs in both males and females. »
A type of radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near… »
Control of translation is one of the major regulatory events in eukaryotic gene expression. Internal ribosome entry sites (IRES) were first… »
Internal ribosome entry site (IRES) is a translational cis-acting element that directs ribosomes to the start codon by a cap-independent mechanism. … »
Two veins running parallel to their corresponding internal mammary arteries that unite forming one vessel. These veins drain the chest wall into… »
Concerning or belonging to two or more nations. »
International Agency for Research on Cancer is part of the World Health Organization that coordinates and conducts both epidemiological and laboratory research… »
An international research organization based in Milwaukee, Wisconsin that collects and analyzes data of recipients of allogeneic and autologous hematopoietic stem cell… »
A group dedicated to innovative clinical research designed to improve the prognosis of women with breast cancer. Patients and investigators from six… »
International Bureau of Weights and Measures (BIPM, for Bureau International des Poids et Mesures) is the agency which was given authority by… »
The International Cancer Research Portfolio (ICRP) is a searchable database of information on cancer research awards of the cancer funding organizations that… »
A textual identifier for chemical substances designed to provide a standard and human-readable way to encode molecular information that also facilitates searches… »
A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in… »
The International Classification of Diseases for Oncology has been used for nearly 25 years as a tool for coding diagnoses of neoplasms… »
The second edition of the International Classification of Diseases for Oncology, published by the World Health Organization in 1992, and used for… »
The third edition of the International Classification of Diseases for Oncology, published in 2000, used principally in tumor and cancer registries for… »
The ninth version of the International Classification of Diseases (ICD), published by the World Health Organization in 1977. »
An extension of the ICD-9 created by the U.S. National Center for Health Statistics so that the system could be used to… »
The tenth version of the International Classification of Diseases (ICD), published by the World Health Organization in 1992. »
The International Commission on Radiation Units and Measurements (ICRU) was established in 1925 by the International Congress of Radiology. Since its inception,… »
International consortium of over 25 groups and multiple investigators pursuing collaborative research on the epidemiology of prostate cancer. The consortium was first… »
A traditional unit of length defined by the U.S. National Bureau of Standards as 30.48 centimeters. It is equal to 0.3048 meter,… »
A staging system for metastatic malignant germ cell tumors developed by the International Germ Cell Cancer Collaborative Group. It is a… »
A collaboration among scientists in Japan, the U.K., Canada, China, Nigeria, and the U.S. to develop a haplotype map of the human… »
The spread of a disease doesn't stop at a country's borders. With more people traveling to other countries and living in… »
A standardized survey developed and published by Raymond C. Rosen and colleagues in 1997 which is used to assess erectile function. This… »
The International Medical Terminology is a clinically validated standard terminology for the reporting of regulatory activities, originally based upon the Medical Dictionary… »
INFOODS was established in 1984 on the basis of the recommendations of an international group convened under the auspices of the United… »
A classification system established by adopting the original system proposed by Shimada with subsequent revisions. The INPC distinguishes favorable and unfavorable histology… »
A standard approach to aid in the stratification of neuroblastoma risk and disease evaluation. »
A classification system developed to establish a consensus approach for pretreatment risk stratification of neuroblastomas. »
A surgicopathological staging system for neuroblastoma, based on the Evans staging system. »
A system, commonly called the INR, established by the World Health Organization (WHO) and the International Committee on Thrombosis and Hemostasis for… »
A measure of the extrinsic pathway of coagulation. The International Normalized Ratio of Prothrombin Time (INR) is the ratio of a patient… »
A list of five factors that help doctors assess how a non-Hodgkins lymphoma patient might respond to a certain treatment or predict… »
A system for scoring myelodysplasia syndrome progression risk, based on a combination of: percentage of blast cells in the bone marrow, the… »
A screening tool used to screen for, diagnose, track, and manage the symptoms of benign prostatic hyperplasia. »
Provides a top level guide to the main databases that describe the proteomes of higher eukaryotic organisms. IPI effectively maintains a database… »
An internationally unique identifier for a data element. »
The International Society of Preventive Oncology (ISPO) is the forum of an international membership committed to the study of interactive etiologic factors… »
A method of staging myeloma published by the International Myeloma Working Group in 2003. »
A non-SI unit of energy defined by the Fifth International Conference on the Properties of Steam, London, 1956, as 1/860 x international… »
The International System of Units (Systeme International d'Unites, SI) is a decimal system of weights and measures derived from and extending the… »
The International Union Against Cancer (UICC) is the only global cancer organisation with members and activities covering all aspects of cancer… »
An organization of national chemistry societies. It acts as an authority in developing standards for the naming of the chemical elements and… »
A unit used to measure the activity of many vitamins, hormones, enzymes, and drugs. An International Unit is the amount of a… »
An arbitrary unit of measurement of the specific biological activity of vitamin A, defined by the International Conference for Unification of Formula… »
International units per day. »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one gram of substance. … »
International units per hour. »
An arbitrary unit of substance content expressed in international units of biological activity per one kilogram of mass of the system. It… »
A dose calculation unit equal to one international unit (an arbitrary unit of biological activity) of a product per one kilogram of… »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one liter of the system… »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one milligram of substance. … »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit of alpha-Tocopherol per one milligram of… »
A unit of arbitrary substance concentration with biologic activity defined as the concentration of international unit(s) per milligram of creatinine. »
A unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one milliliter of system… »
International units per minute. »
International units per second. »
A dose calculation unit expressed as a number of arbitrary units of biological activity (International Units) of substance per square meter of… »
A worldwide, decentralized network of computer networks connecting individuals and organizations to information and electronic mail services. »
The entity that oversees global IP address allocation, root zone management for the Domain Name System (DNS), media types, and other Internet… »
Internet Electronic Communication »
Internet Mobile Technology (e.g. iphone, mobile websites, epocrates) »
An item located online that cannot be classified within a particular set of terms. »
For most kids and teens, technology is an important part of their lives. They browse the Web for information, use social… »
Internet Social Media (e.g. facebook, twitter, myspace) »
A general term for any neurons which are not motor or sensory. Interneuron may also refer to neurons whose axons remain within… »
A doctor who specializes in internal medicine. An internist works with adult patients to prevent, diagnose, and treat diseases without using… »
Either of three arteries including the common interosseous artery which arises from the ulnar artery and bifurcates into the anterior and posterior… »
One of two deep veins (anterior or posterior) that run parallel to their corresponding artery in the forearm to drain the wrist… »
A cavity within the subarachnoid space between the two temporal lobes and in front of the pons. »
A short or long-term association between two or more people, including kinship relations, romantic, business, and social interactions. »
Hinge joints between the phalanges of the hand or foot. »
A ginglymoid (hinge) synovial joint within the first digit of the hand or foot connecting the proximal and distal phalanges. »
A ginglymoid (hinge) synovial joint between the phalanges of the second digit of the hand or foot. »
A ginglymoid (hinge) synovial joint between the phalanges of the third digit of the hand or foot. »
A ginglymoid (hinge) synovial joint between the phalanges of the fourth digit of the hand or foot. »
A ginglymoid (hinge) synovial joint between the phalanges of the fifth digit of the hand or foot. »
The hinge synovial joints between the bones of the toes. »
The hinge synovial joints between the phalanges of the fingers. »
A condyloid synovial joint within the thumb connecting the proximal and distal phalanges. »
A cell in a resting state. Individual chromosomes are not visible. The cell performs all biochemical and physiologic functions and replication of… »
Interphase chromosomes are decondensed chromosomes that reside in the interphase nucleus in the form of chromatin. Two types of chromatin, euchromatin and… »
The interval between two successive cell divisions during which the chromosomes are not individually distinguishable. Interphase is considered the resting stage of… »
An electrocardiographic finding of a premature ventricular complex which occurs between two normal QRS complexes which have normal timing. »
The substitution of missing data with an estimated value that falls between known data points. »
An act or process of elucidation; explication, or explanation of the meaning of the event or thing via the assignment of objects… »
Someone who mediates between speakers of different languages. »
Psychotherapy of the Freudian school. In this form of psychotherapy, symbols from the patient's verbalizations, dreams, and interactions are interpreted for… »
A computer program developed by the European Bioinformatics Institute that scans an input protein sequence against a range of stored protein… »
The difference between the 3d and 1st quartiles is called the interquartile range and it is used as a measure of variability… »
A rare congenital cardiovascular disorder characterized by the presence of a gap between the ascending and descending portions of the thoracic… »
A device designed to stop the flow of current in a circuit. »
A time interval during which there is a temporary cessation of something. »
The time span of a disruption in an event. »
The unit of measure for the duration of an interruption in treatment. »
Intersectin-1 (1721 aa, ~195 kDa) is encoded by the human ITSN1 gene. This protein plays a role in the regulation of both… »
A junction where one street or road crosses another. »
A person (one of unisexual specimens) who is born with genitalia and/or secondary sexual characteristics of indeterminate sex, or which combine features… »
An interstitial cell is a cell that is part of the connective and soft tissues. »
A specialized cell found throughout the gastrointestinal tract. These cells are essential for normal gastrointestinal motility by functioning as the pacemaker cells… »
A non-neuronal cell that supports the pineal gland. It resembles an astrocyte and is found around blood vessels and among groups of… »
A hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their eggs and to… »
Interstitial collagenase (469 aa, ~54 kDa) is encoded by the human MMP1 gene. This protein plays a role in collagenolysis. »
Inflammation of the urinary bladder wall leading to urinary frequency, urgency, and discomfort, pelvic pain, and pain during intercourse. Morphologically it is… »
A disease occurring chiefly in the connective-tissue framework of an organ. »
Pathologic accumulation of air in the interstitium of the lungs. It is caused by the rupture of alveoli and terminal bronchioles. It… »
Fluid found in the spaces around cells. It comes from substances that leak out of blood capillaries (the smallest type of blood… »
Photodynamic therapy used to treat deep-seated solid tumors. »
Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. The inflammation and scarring… »
A renal disorder characterized by inflammation and edema of the interstitial tissue of the kidney. »
Inflammation of interstitial lung tissue, usually associated with infection. »
A type of internal radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into a… »
Drug administration to or in the interstices of a tissue. »
The very narrow portion of the fallopian tube passing through the uterine wall into the uterine cavity. »
The region that circles the Earth, near the equator, where the trade winds of the Northern and Southern Hemispheres come together. … »
A data type comprised of a set of consecutive values of an ordered base data type. »
One of the nodes that lie along the course of a lymphatic vessel between a primary melanoma site and a recognized node… »
A data type comprised of a set of consecutive values of an ordered point in time date and time datatype. »
A data type comprised of a set of consecutive values of an ordered point in time date datatype. »
A data type comprised of a set of consecutive values of an ordered point in time integer datatype. »
A data type comprised of a set of consecutive values of an ordered base, which is an abstract generalization for all value… »
A scale that uses ordered numbers with a constant difference but with no natural zero and where difference makes sense but ratios… »
An artifact resulting from the presence of another body structure between the target and the receiver. »
An artifact resulting from the presence of a foreign body between the target and the receiver. »
In medicine, a treatment or action taken to prevent or treat disease, or improve health in other ways. »
The Intervention Community Trial is a controlled study that involves modification of causal or conjectural causal factors in a population to test… »
The period of time during which an intervention continues. »
The group receiving the study agent that is being tested in a clinical trial or clinical study. »
An integer specifying the number of intervention groups. »
The trial design developed to compare treatment groups. »
An activity that produces an effect, or that is intended to alter the course of a disease in a patient or… »
A patient condition when action or ministration whose purpose is to improve health or to alter the course of a disease is… »
A pre-clinical or clinical study in human beings in which individuals are assigned by an investigator based on a protocol to receive… »
The kind of product or procedure studied in a trial. »
The branch of radiology concerned with the use of radiation to treat disease. »
Studies in which individuals are assigned by an investigator based on a protocol to receive specific interventions. Subjects may receive diagnostic, therapeutic… »
An action plan of a pre-clinical or clinical study in which individuals are assigned by an investigator based on a protocol to… »
Specifies whether persons who have not had the condition(s) being studied or otherwise related conditions or symptoms, as specified in the eligibility… »
A coded value specifying the method of assigning subjects to treatment or control groups. »
A coded value specifying the roles of individuals who are masked for single or double blind studies. »
A coded value specifying the type of masking used on a study protocol to ensure that the results are not biased by… »
A coded value specifying the temporal relationships of the control to the study intervention. »
A coded value specifying the kind of comparison or comparator against which the study treatment is evaluated. »
An integer specifying the number of intervention groups. »
A character string that provides the key details of the intervention. »
The wall that separates the left and right ventricles of the heart. »
Spongy discs located between the vertebrae of the spinal column; composed of the outer annulus fibrosus and inner nucleus pulposus. »
A conversation with an individual regarding his or her background and other personal and professional details, opinions on specific subjects posed by… »
The person who answers the questions during an interview. »
The person who manages an interview and asks the questions. »
Having to do with the intestines. »
A congenital malformation characterized by the absence of a normal opening in a part of the intestine. It can occur either in… »
Your small intestine is part of your digestive system. It is a long tube that connects your stomach to your large… »
A classification of inherited or acquired disorders of sugar metabolism. Deficiencies of lactase, maltase or sucrase-isomaltase usually occur irreversibly and independent of… »
A non-neoplastic or neoplastic disorder that affects the small or large intestine. »
A rare congenital abnormality characterized by the presence of a duplicated segment of the intestine. The duplicated segment is cystic. »
An abnormal communication between the small or large intestine and another organ or cavity. »
Bacteria and other organisms that live inside the intestines. They help digest food. Vitamins such as biotin and vitamin K are made… »
A usually indolent, extra-adrenal paraganglioma affecting the intestine. Patients may present with gastrointestinal hemorrhage. Unlike the conventional paragangliomas, this tumor has a… »
The intestine is the largest lymphoid tissue in the body. One striking feature of intestinal immunity is its ability to generate great… »
A precancerous neoplastic process that affects the small or large intestine. It is characterized by low or high grade dysplasia of… »
A congenital abnormality in which the intestine is abnormally rotated (twisted). It may result in intestinal obstruction. »
A morphologic finding indicating the replacement of epithelial tissue outside the intestines by intestinal-type epithelium. »
A morphologic finding indicating the replacement of part of the columnar epithelium by intestinal-type epithelium. »
A finding indicating the replacement of part of the esophageal mucosal epithelium by intestinal-type epithelium. »
A morphologic finding indicating the replacement of part of the gastric mucosal epithelium with intestinal-type epithelium. Using immunohistochemical staining, gastric intestinal… »
Bacteria and other organisms that live inside the intestines. They help digest food. Vitamins such as biotin and vitamin K are made… »
A necrotic process involving the intestinal wall. »
A benign or malignant neoplasm involving the small or large intestine. »
An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the small or large intestine. The mitotic count is… »
A neoplasm with neuroendocrine differentiation that arises from the small or large intestine. It includes well differentiated neuroendocrine tumors (low and… »
A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the small or large intestine. »
A well differentiated, low grade neuroendocrine tumor (carcinoid tumor) that arises from the small or large intestine. The mitotic count is… »
A well differentiated, intermediate grade tumor with neuroendocrine differentiation that arises from the small or large intestine. The mitotic count is… »
An intestinal obstruction occurs when food or stool cannot move through the intestines. The obstruction can be complete or partial. There are… »
A rupture in the wall of the small or large intestine due to traumatic or pathologic processes. »
Obstruction of the intestines that is functional, not mechanical. »
Leakage of contents from the intestinal stoma. »
A blockage of the intestinal stoma. »
An intestinal stoma complication characterized by protrusion of the stoma above the abdominal surface. »
A finding of blood leakage from the intestinal stoma. »
Fibrosis of the wall of a segment of the intestine that leads to intestinal lumen narrowing. »
An adenocarcinoma arising from epithelium which has undergone intestinal metaplasia. Representative examples include gastric, gallbladder, and ampulla of Vater intestinal type… »
Tiny hair-like projections that line the inside of the small intestine. They contain blood vessels and help absorb nutrients. »
A finger-like projection of the plasma membrane found in the epithelial cells lining the intestinal tract that increase the lumen surface… »
Twisting of a loop of bowel that results in intestinal obstruction. »
The tissue that forms the wall of the small and large intestine. It consists of mucosa, submucosa, muscular coat, and serosal… »
The long, tube-shaped organ in the abdomen that completes the process of digestion. The intestine has two parts, the small intestine and… »
Surgical removal of part or all of the intestine. »
A pan alpha-v human monoclonal antibody that recognizes alpha-v beta-1, alpha-v beta-3, alpha-v beta-5, and alpha-v beta-6 integrins with antiangiogenic and antitumor… »
A condition of close feelings shared between two people. Intimacy includes emotional intimacy and physical intimacy. »
Pertaining to the inner layer of the blood vessels. »
A malignant neoplasm arising from the large blood vessels. It is characterized by the presence of tumor cells that grow within… »
An antineoplastic agent. »
An inability to absorb or metabolize certain substances in the normal way. »
A substance that has been studied in the treatment of some types of cancer. Intoplicine blocks certain enzymes needed for cell division… »
An herb native to islands in the South Pacific. Substances taken from the root have been used in some cultures to relieve… »
The range of possible values for any measurable characteristic, physical or mental, of a human being, analyzed, examined, investigated, experimented upon, or… »
Within the abdomen. »
A hemangioma arising from organs within the abdominal cavity. »
Bleeding within the abdominal cavity. »
Any lymph node within the abdomen. »
A lymphangioma arising from the organs of the abdominal cavity. »
A benign or malignant extra-adrenal paraganglioma arising from the abdominal cavity. »
A medical device that increases myocardial oxygen perfusion while at the same time increasing cardiac output. »
Within an artery (blood vessel that carries blood from the heart to tissues and organs in the body). »
A type of radiation therapy used to treat liver cancer that is advanced or has come back. Tiny beads that hold the… »
An electrocardiographic finding of a delay in impulse propagation through the atria. This is characterized by broad P waves which are often… »
Administration of the drug within the abdominal cavity, typically as a loco-regional therapy for disease confined to the abdomen. »
Administration of the drug within the amnion. »
Intraarterial drug injection or infusion is a method of delivering a drug directly into artery or arteries to localize its effect to… »
Administration of the drug within a joint. »
Administration within the biliary system for selective delivery of the agent to targeted hepatobiliary tissues and cell types, the goal of which… »
Administration of a drug within a bronchus or bronchi. The intrabronchial drug delivery can be used for both local and systemic drug… »
Administration of a drug within a bursal cavity. »
Administration of a substance by injection directly into the anterior chamber of the eye. »
A morphologic variant of fibroadenoma without clinical significance. It is characterized by distortion and compression of the ducts by proliferating stromal… »
Administration of a drug within the heart. Concept refers both to administration into myocardium and within a chamber of the heart. … »
The introduction of fluids and drugs directly into the carotid artery, the main artery in the neck that carries blood from the… »
The introduction of fluids and drugs directly into the carotid artery, the main artery in the neck that carries blood from the… »
Administration of a drug within a cartilage. »
Administration of a drug within the cauda equina. »
Administration of a drug within a pathologic cavity. »
Within a cavity or space, such as the abdomen, pelvis, or chest. »
A type of internal radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into a… »
Administration of a drug within any natural, non-pathologic cavity, such as that of cervix, uterus, or penis. »
Inside a cell. »
Any subcellular process that acts to positively regulate the catalytic activities that underlie intracellular signaling. »
Any subcellular process that acts to negatively regulate the catalytic activities that underlie intracellular signaling. »
A thin pliable sheet separating organelles from the protoplasm. »
The process whereby cellular proteins are positioned and sequestered in the correct cellular compartment for proper function. The process of moving… »
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They… »
Any subcellular process that is initated by a chemical or mechanical stimulus and results in a specific cellular response. »
Any subcellular or molecular event, process, or condition involved in translocation of a biological macromolecule from one site or compartment to another,… »
Of, ocurring in, or situated within the cerebrum. »
A cystic meningioma that grows within the cerebral hemispheres. »
Administration of a drug within the cerebrum, directly into brain tissue, usually by injection or direct application. »
Retroviral-like intracisternal A particles. High copy number family of repeated elements in the mouse with a typical proviral organization. Expressed… »
The intracisternal route involves Administration of a drug directly into the cerebrospinal fluid of the brain ventricles. It could be performed by… »
Within the clavicles. »
Within the colon. »
Administration of a drug within the eye cornea. »
Administration of a drug within a crown of tooth. »
A device for use within the coronary anatomy. »
Administration of a drug within the coronary arteries supplying blood to the tissues of the heart. »
Administration of a drug within the dilatable venous spaces of the cavernous tissue of the penis. »
Situated or occurring within the cranium; affecting or involving intracranial structures. »
A congenital or acquired aneurysm within the cranium. »
A term referring to the brain area that is supplied by both the right and the left internal carotid arteries and their… »
Arteries which have their origins within the intracranial cavity. »
A cavernous hemangioma arising from the brain and meninges. »
Colloid cysts i.e. cysts filled with gelatinous material, in the central nervous system often are found in the third ventricle. Due to… »
An extraskeletal myxoid chondrosarcoma arising from the structures within the cranium. »
A hemangioma arising from the brain and meninges. »
Bleeding within the cranium. »
A finding characterized by increased cerebrospinal fluid pressure within the skull. »
A multinodular intermediate fibrocytic neoplasm arising from the intracranial soft tissue or viscera. It is characterized by the presence of spindle-shaped… »
A non-neoplastic or neoplastic pathologic process affecting the leptomeninges of the brain. »
A rare benign adipose tissue neoplasm located in the intracranial region. It is a congenital hamartomatous malformation derived from the embryologic meninx… »
A malignant adipose tissue neoplasm of the intracranial region. »
A meningioma that arises within the cranial cavity. »
A myeloid sarcoma that affects the meninges or the cerebral hemispheres. »
A benign or malignant neoplasm that arises from or metastasizes to structures within the cranium. This includes meningeal and other tumors… »
The brain, intracranial portions of the cranial nerves, intracranial blood vessels, intracranial meninges and other surrounding and supporting structures contained with the… »
A central nervous system primitive neuroectodermal tumor arising from the brain. »
Administration of a drug within the skull. »
A tumor that occurs in the brain. »
Two groups of blood vessels, deep and superficial intracranial veins, that drain deoxygenated blood from the brain. »
Within the skin. Also called intradermal. »
A carcinoma entirely confined to the ducts. While intraductal (or DCIS) carcinomas can arise at other sites, these terms are universally… »
An intraductal breast carcinoma characterized by a papillary growth within a large cystic duct. There is no evidence of invasion of the… »
A papillary epithelial neoplasm arising in a cystically dilated breast duct. »
A morphologic finding indicating the presence of fine granular yellowish-brownish pigment within the cytoplasm of the cells in a tissue sample. … »
Within the skin. Also called intracutaneous. »
A nevus characterized by the proliferation of nevus cells in the dermis without involvement of the dermal-epidermal junction. »
Intradermal injection is a method of drug administration within the substance of the skin, particularly the dermis. »
Administration of a drug within a fibrocartilaginous intervertebral disc. »
A breast carcinoma characterized by the presence of a ductal carcinoma in situ component and an in situ or invasive lobular carcinomatous… »
A neoplastic process characterized by the proliferation of spindle to cuboidal myoepithelial cells within small breast ducts. »
A benign or malignant epithelial neoplasm that arises anywhere in the ductal system of the breast. This category includes intraductal papilloma,… »
A benign (not cancer), wart-like growth in a milk duct of the breast. It is usually found close to the nipple and… »
A benign breast neoplasm characterized by the proliferation of multiple papillomas within the lumen of the ducts. »
A noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread… »
A ductal carcinoma in situ of the breast characterized by the presence of a cribriform architectural pattern. »
An intraductal papillary carcinoma in which the neoplastic epithelial cells are arranged in micropapillary patterns. »
A ductal carcinoma in situ of the breast characterized by the presence of sheets of tumor cells without evidence of central necrosis… »
A breast adenocarcinoma characterized by the presence of an intraductal papillary carcinomatous component and an invasive carcinomatous component. »
A non-invasive, papillary epithelial neoplasm that arises from the epithelium of the intrahepatic or extrahepatic bile ducts. »
A non-invasive breast adenocarcinoma located in a distended duct. It is characterized by the presence of papillary structures with fibrovascular stalks. In… »
A benign or malignant papillary neoplasm that arises anywhere in the ductal system of the breast. It is characterized by fibrovascular… »
A benign (not cancer), wart-like growth in a milk duct of the breast. It is usually found close to the nipple and… »
A neoplastic process characterized by the presence of multiple intraductal papillomas. »
A group of non-invasive epithelial proliferations that occur in the ductal system of the breast. The vast majority of cases arise… »
Administration of a drug within the duct of a gland. »
Administration of a drug within the duodenum. »
A neoplasm that occurs within the spinal canal in the space between the spinal cord and the dura mater. Representative examples… »
An area within the dura sheath but outside of the spinal cord. »
Administration of a drug within or beneath the dura mater. »
A rare cutaneous lesion presenting as a scaly verrucous plaque. Morphologically, the plaque contains nests of basaloid cells. »
Administration of a drug within the superficial epithelial layer of the skin. »
Within the layer of cells that form the surface or lining of an organ. »
A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of… »
Glandular intraepithelial neoplasia arising in Barrett esophagus. »
A focal, non-invasive epithelial lesion composed of cells with atypical cytology and/or organization and risk of progressing to malignancy. Biological proof that… »
Administration of a drug within the cellular avascular layer covering internal and external surfaces of the body, its parts, organs, and… »
A mature T lymphocyte that migrates into epithelial tissue and contributes to the local and the systemic immune response. »
A mature T lymphocyte, found in the intestinal lining that differentiates from its precursor outside the thymus, most likely in an area… »
A method for monitoring the pH in the distal esophagus for the detection of acid reflux and the diagnosis of gastroesophageal reflux… »
Administration of a drug within the esophagus. »
Administration of a medicinal product into an ovarian follicle. »
Administration of a drug within the stomach, e.g. via gavage or via gastrostomy. »
Administration of a drug within the gingivae. »
Within the liver. »
A bile duct that passes through and drains bile from the liver. »
A rare adenoma that arises from the intrahepatic biliary tree. »
A neoplastic, non-invasive lesion that affects the intrahepatic bile duct epithelium. It is characterized by the presence of atypical epithelial cells… »
A rare cancer that forms in the bile ducts inside the liver. A bile duct is a tube that carries bile (fluid… »
A clinical finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
Intrahepatic bile duct cancer with solitary tumor with vascular invasion or multiple tumors, with or without vascular invasion. »
Epithelium composed of one or more layers of glandular epithelial cells and a basement membrane lining the lumen of the intrahepatic bile… »
An adenoma that arises from the intrahepatic bile ducts and it is characterized by the presence of microcystic changes. »
A mucinous cystic neoplasm that arises from the intrahepatic bile ducts. »
A mucinous cystic neoplasm that arises from the intrahepatic bile ducts and it is associated with an invasive carcinomatous component. »
