Medicine
This gene is involved in transcriptional regulation and in the regulation of endometrial development. »
Human HOXA10 wild-type allele is located within 7p15-p14 and is approximately 10 kb in length. This allele, which encodes homeobox protein Hox-A10,… »
This gene is involved in embryologic pattern formation. »
Human HOXA11 wild-type allele is located in the vicinity of 7p15.2 and is approximately 4 kb in length. This allele, which encodes… »
This gene plays a role in transcriptional modulation. »
Human HOXA13 wild-type allele is located in the vicinity of 7p15.2 and is approximately 7 kb in length. This allele, which encodes… »
This gene plays a role in both transcription and anterior/posterior axis formation. »
Human HOXA3 wild-type allele is located in the vicinity of 7p15.2 and is approximately 46 kb in length. This allele, which encodes… »
This gene is involved in spatial and temporal regulation of gene expression during embryonic development. »
Human HOXA7 wild-type allele is located in the vicinity of 7p15.2 and is approximately 4 kb in length. This allele, which encodes… »
This gene plays a role in transcriptional regulation, morphogenesis and differentiation. »
Human HOXA9 wild-type allele is located within 7p15-p14 and is approximately 7 kb in length. This allele, which encodes homeobox protein Hox-A9,… »
A family of genes found in a cluster on the q arm of chromosome 17. These genes encode transcription factors that play… »
This gene is involved in anterior-posterior axis formation. »
Human HOXB13 wild-type allele is located in the vicinity of 17q21.32 and is approximately 4 kb in length. This allele, which encodes… »
This gene plays a role in spatial regulation of gene expression during embryonic development. »
Human HOXB4 wild-type allele is located in the vicinity of 17q21.32 and is approximately 5 kb in length. This allele, which encodes… »
This gene is involved in the modulation of embryonic gene expression. »
Human HOXB6 wild-type allele is located in the vicinity of 17q21.32 and is approximately 11 kb in length. This allele, which encodes… »
This gene is involved in both embryonic development and transcriptional regulation. »
Human HOXB9 wild-type allele is located in the vicinity of 17q21.3 and is approximately 5 kb in length. This allele, which encodes… »
This gene is involved in embryological development. »
Human HOXC11 wild-type allele is located in the vicinity of 12q13.13 and is approximately 3 kb in length. This allele, which encodes… »
This gene plays a role in the modulation of transcription. »
Human HOXC13 wild-type allele is located in the vicinity of 12q13.13 and is approximately 8 kb in length. This allele, which encodes… »
This gene plays a role in transcriptional repression, morphogenesis and differentiation. »
Human HOXC6 wild-type allele is located within 12q13.3 and is approximately 14 kb in length. This allele, which encodes homeobox protein Hox-C6,… »
This gene is involved in limb morphogenesis. »
Human HOXD11 wild-type allele is located in the vicinity of 2q31.1 and is approximately 6 kb in length. This allele, which encodes… »
This gene plays a role in the development of limbs and appendages. »
Human HOXD13 wild-type allele is located in the vicinity of 2q31.1 and is approximately 3 kb in length. This allele, which encodes… »
This gene plays a role in hemoglobin interactions and in the prevention of oxidative tissue damage. »
Human HP wild-type allele is located in the vicinity of 16q22.1 and is approximately 6 kb in length. This allele, which encodes… »
Trastorno benigno (no canceroso) en el que el tejido de la próstata crece en exceso, hace presión contra la uretra y la… »
This gene plays a role in signal transduction and is involved in the regulation of cytosolic calcium ion concentration. »
Human HPCA wild-type allele is located within 1p35-p34.2 and is approximately 8 kb in length. This allele, which encodes neuron-specific calcium-binding protein… »
Human HPGD wild-type allele is located within 4q34-q35 and is approximately 32 kb in length. This allele, which encodes 15-hydroxyprostaglandin dehydrogenase [NAD+]… »
Human HPN wild-type allele is located within 19q11-q13.2 and is approximately 26 kb in length. This allele, which encodes serine protease hepsin… »
2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a. A drug that is used in photodynamic therapy that is absorbed by tumor cells; when exposed to light, it becomes… »
2-(1-hexiloetilo)-2-devinilo pirofeoforbida-a. Medicamento usado en la terapia fotodinámica que las células tumorales absorben. Se activa cuando se expone a la luz y… »
This gene plays a role in the innate immunity of humans to a non-pathogenic species of African trypanosomes. »
Human HPR wild-type allele is located in the vicinity of 16q22.1 and is approximately 3 kb in length. This allele, which encodes… »
This gene is involved in purine/pyrimidine metabolism. »
Human HPRT1 wild-type allele is located in the vicinity of Xq26.1 and is approximately 40 kb in length. This allele, which encodes… »
This gene plays a putative role in transcription. »
Human HPRT2 wild-type allele is located at an unknown chromosomal location and its length is also unknown. This allele, which encodes hypoxanthine… »
Human HPSE wild-type allele is located in the vicinity of 4q21.3 and is approximately 43 kb in length. This allele, which encodes… »
This gene is involved in extracellular matrix remodeling. »
Human HPSE2 wild-type allele is located within 10q23-q24 and is approximately 777 kb in length. This allele, which encodes heparanase-2 protein, plays… »
Sustancia producida por la glándula paratiroidea que ayuda al cuerpo a almacenar y usar el calcio. Una cantidad de la HPT más… »
A type of virus that can cause abnormal tissue growth (for example, warts) and other changes to cells. Infection for a long… »
A peptide derived from the oncogenic human papillomavirus (HPV) early gene product E6. The HPV 16 transforming protein E6 is expressed… »
A peptide based vaccine consisting of amino acids 12 through 20 of the E7 gene of the Human Papilloma Virus type… »
A synthetic peptide vaccine consisting of amino acids 86 through 93 (TLGIVCPI) of the viral oncoprotein human papillomavirus (HPV) 16 E7. Vaccination… »
A vaccine consisting of human papillomavirus-derived noninfectious virus-like particles (VLPs), containing the L1 major capsid protein. Vaccination with HPV 16 L1-VLP… »
A synthetic peptide vaccine consisting of amino acids 13 through 21 of the viral oncoprotein human papillomavirus (HPV) 18 E6. The HPV… »
Noninfectious, synthetic, virus-like particles (VLP) containing the major viral capsid protein, L1, of the human papillomavirus type 18 with potential immunoprotective… »
A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus (HPV) subtypes 16 and 18, respectively,… »
DNA probes specific for the identification of human papilloma virus. »
A laboratory test in which cells are scraped from the cervix to look for DNA of human papillomaviruses (HPV). HPV can cause… »
A topical gel composed of a human papillomavirus (HPV) E1/E2 protein:protein interaction (PPI) inhibitor with potential antiviral activity. Upon topical application of… »
A therapeutic DNA vaccine encoding the E6/E7 fusion protein of human papillomavirus (HPV) subtypes 16 and 18, plus the immune-enhancer, Fms-like tyrosine… »
A laboratory test in which cells are scraped from the cervix to look for RNA of the most common types of human… »
A laboratory test in which cells are tested for DNA or RNA from certain types of human papillomavirus (HPV) that are known… »
A vaccine used to prevent genital warts, anal cancer, cervical cancer, vulvar cancer, and vaginal cancer caused by certain types of human… »
A vaccine directed against Human Papillomavirus Type 11 that causes majority of the genital warts and anogenital cancers. »
A human papillomavirus (HPV) type 16 vaccine containing four E6 peptides in combination with the extract of Candida albicans, with potential immunomodulating… »
Any of a number of strains of human papilloma virus (HPV) that have been shown to cause cancer in humans. »
A procedure in which a human papillomavirus (HPV) test and a Pap test are done at the same time to check for… »
A gene that may cause cancer when it is mutated (changed). The Hras gene makes the HRAS protein, which is involved in… »
Human HRAS wild-type allele is located in the vicinity of 11p15.5 and is approximately 3 kb in length. This allele, which encodes… »
Human HRG wild-type allele is located in the vicinity of 3q27 and is approximately 12 kb in length. This allele, which encodes… »
This gene is involved in the regulation of gastric acid secretion, gastrointestinal motility, and intestinal secretion. »
Human HRH2 wild-type allele is located in the vicinity of 5q35.2 and is approximately 2 kb in length. This allele, which encodes… »
Human HRK wild-type allele is located in the vicinity of 12q24.23 and is less than 1 kb in length. This allele, which… »
Hormones (estrogen, progesterone, or both) given to women after menopause to replace the hormones no longer produced by the ovaries. Also called… »
This gene plays a role in the modification of heparan sulfate. »
Human HS6ST2 wild-type allele is located in the vicinity of Xq26.2 and is approximately 335 kb in length. This allele, which encodes… »
Hsc70-interacting protein (369aa, ~41 kDa) is encoded by the human ST13 gene. This protein plays a role in the modulation of protein… »
This gene is involved in corticosteroid metabolism. »
Human HSD11B1 wild-type allele is located within 1q32-q41 and is approximately 49 kb in length. This allele, which encodes corticosteroid 11-beta-dehydrogenase isozyme… »
This gene is involved in estrogen biosynthesis. »
Human HSD17B1 wild-type allele is located within 17q11-q21 and is approximately 4 kb in length. This allele, which encodes estradiol 17-beta-dehydrogenase 1… »
This gene plays a role in hormonal signaling. »
Human HSD17B2 wild-type allele is located within 16q24.1-q24.2 and is approximately 63 kb in length. This allele, which encodes estradiol 17-beta-dehydrogenase 2… »
This gene plays a role in the metabolism of testosterone. »
Human HSD17B3 wild-type allele is located in the vicinity of 9q22 and is approximately 67 kb in length. This allele, which encodes… »
This gene is involved in androgen catabolism. »
Human HSD17B6 wild-type allele is located in the vicinity of 12q13 and is approximately 36 kb in length. This allele, which encodes… »
This gene is involved in regulation of the biological potency of certain steroids. »
Human HSD17B7 wild-type allele is located within 1q23 and is approximately 22 kb in length. This allele, which encodes 3-keto-steroid reductase protein,… »
This gene plays a role in the biosynthesis of hormonal steroids. »
Human HSD3B2 wild-type allele is located in the vicinity of 1p13.1 and is approximately 8 kb in length. This allele, which encodes… »
This gene plays a role in the activation of transcription in response to environmental stress. »
Human HSF1 wild-type allele is located in the vicinity of 8q24.3 and is approximately 23 kb in length. This allele, which encodes… »
Cells of the uterine cervix that are moderately or severely abnormal and may become cancer. Also called high-grade squamous intraepithelial lesion. … »
Células del cuello uterino que son moderada o gravemente anormales, y podrían volverse cancerosas. También se llama lesión intraepitelial escamosa de grado… »
One of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or… »
Pertenece a un grupo de proteínas que ayudan a proteger las células del estrés que les producen elementos como el calor, el… »
Vacuna que se elabora con las células tumorales de un paciente; puede ayudar al sistema inmunitario del cuerpo a destruir células… »
A second-generation antisense oligonucleotide targeting heat shock protein 27 (Hsp27) with potential antitumor and chemosensitizing activities. Hsp27 antisense oligonucleotide OGX-427 suppresses tumor… »
Mammalian cells can respond to a variety of stresses such as heat, cold, oxidative stress, metabolic disturbance, and environmental toxins through necrotic… »
An agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be… »
Hsp90 co-chaperone Cdc37 (378 aa, ~44 kDa) is encoded by the human CDC37 gene. This protein is involved in post-translational protein… »
An orally bioavailable nanoparticle albumin-bound inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor AB-010 selectively binds to… »
A synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor AT13387 selectively binds to… »
A derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been… »
An orally active inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90, a chaperon protein upregulated in a variety… »
A small-molecule inhibitor of heat shock protein (Hsp) 90 with potential antineoplastic activity. Hsp90 inhibitor BIIB028 blocks the binding of oncogenic client… »
An orally active and small molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor Debio 0932 specifically… »
An orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor Hsp990 binds to and inhibits the… »
An orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor MPC-3100 selectively binds… »
A purine-based heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor PU-H71 specifically inhibits active Hsp90, thereby inhibiting its… »
The orally bioavailable mesylate salt of a synthetic prodrug targeting the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the… »
The orally bioavailable mesylate salt of a synthetic prodrug targeting the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the… »
An orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor XL888 specifically binds to… »
This gene is involved in both protein folding and nitric oxide metabolism. »
Human HSP90AA1 wild-type allele is located in the vicinity of 14q32.33 and is approximately 59 kb in length. This allele, which encodes… »
This gene plays a role in both interferon signaling and protein folding. »
Human HSP90AB1 wild-type allele is located in the vicinity of 6p12 and is approximately 7 kb in length. This allele, which encodes… »
This gene is involved in protein folding. »
Human HSPA1A wild-type allele is located in the vicinity of 6p21.3 and is approximately 2 kb in length. This allele, which encodes… »
This gene plays a role in protein chaperone activity. »
Human HSPA1B wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes… »
This gene is involved in cellular signal transduction. »
Human HSPA5 wild-type allele is located within 9q34 and is approximately 6 kb in length. This allele, which encodes 78 kDa glucose-regulated… »
This gene is involved in transcriptional regulation, and plays a major role in cellular stress responses. »
Human HSPB1 wild-type allele is located in the vicinity of 7q11.23 and is approximately 2 kb in length. This allele, which encodes… »
HSPB1-associated protein 1 (488 aa, ~55 kDa) is encoded by the human HSPBAP1 gene. This protein may play a role in the… »
This gene plays a role in both protein folding and autophagy. »
Human HSPB8 wild-type allele is located in the vicinity of 12q24.23 and is approximately 16 kb in length. This allele, which encodes… »
This gene may play a role in the cellular stress response. »
Human HSPBAP1 wild-type allele is located in the vicinity of 3q21.1 and is approximately 54 kb in length. This allele, which encodes… »
This gene plays a role in protein folding. »
Human HSPD1 wild-type allele is located in the vicinity of 2q33.1 and is approximately 30 kb in length. This allele, which encodes… »
This gene is involved in basement membrane architecture. »
Human HSPG2 wild-type allele is located within 1p36.1-p34 and is approximately 115 kb in length. This allele, which encodes basement membrane-specific heparan… »
A type of virus that causes herpes infections and has DNA as its genetic material. There are two types of HSVs. … »
A non-engineered, naturally oncolytic, replication-competent spontaneous herpes simplex virus (HSV) type I mutant variant. Upon intratumoral injection, HSV1 HF10 transfects, replicates in,… »
Herpes simplex virus thymidine kinase (HSV-Tk) gene encodes thymidine kinase protein, which is important for herpes simplex virus infection. The TK gene… »
A preparation of donor lymphocytes transduced with the suicide gene herpes simplex virus thymidine kinase (HSV-TK) with potential immunomodulating activity. Administration of… »
The eukaryotic genome is packaged by histone and nonhistone proteins to form chromatin. The assembly of nucleosomes, as well as compaction of… »
hSWI/SNF is an ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis. The complex facilitates transcriptional… »
Human colonic adenocarcinoma cells that are able to express differentiation features characteristic of mature intestinal cells. These cells have mainly been used… »
Bipartite DNA binding domain containing a helix-turn and a leucine zipper. »
Humo que se produce al quemarse un producto de tabaco o humo que exhalan los fumadores. La inhalación del HTA se llama… »
This gene is involved in the regulation of apoptosis and induces cell death. »
Human HTATIP2 wild-type allele is located in the 11p15.1 and is approximately 20 kb in length. This allele, which encodes oxidoreductase HTATIP2… »
Human HTC2 gene is located within Xq24-q27.1 and the size of this phenotypic locus is not reported. This gene region has no… »
A peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with… »
A cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding human telomerase reverse transcriptase (hTERT) and survivin peptide,… »
A cancer vaccine directed against human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic… »
A vaccine containing multiple peptides derived from the human telomerase reverse transcriptase (hTERT), survivin and cytomegalovirus (CMV), with potential immunostimulating and antineoplastic… »
A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and survivin… »
Generic category for HTLV-I and HTLV-II. »
A type of virus that infects T cells (a type of white blood cell) and can cause leukemia and lymphoma. HTLV-1 is… »
An antibody produced by B lymphocytes in response to human T-cell leukemia virus type 1 infection. »
A human deltaretrovirus related to HTLV-1. Although human T-lymphotropic virus-2 (HTVL-2) has been isolated in association with specific diseases it has not… »
Rex gene of the HTLV-I virus. »
Tax gene of the HTLV-I virus. »
Rex gene of the HTLV-II virus. »
Tax gene of the HTLV-II virus. »
A program used to view an HTML document. »
This gene is involved in serotonin-dependent signaling. »
Human HTR1A wild-type allele is located within 5q11.2-q13 and is approximately 2 kb in length. This allele, which encodes 5-hydroxytryptamine receptor 1A… »
HTR2A-C Allele is a variant form of 20-kb 3-exon human HTR2A Gene (GPCR1/5HT2 Family), which encodes Serotonin 5-HT-2A Receptor, a conserved integral… »
HTR2A-T Allele is a variant form of 20-kb 3-exon human HTR2A Gene (GPCR1/5HT2 Family), which encodes Serotonin 5-HT-2A Receptor, a conserved integral… »
This gene plays a role in G protein-coupled receptor signal transduction and sterol metabolism. »
Human HTR2A wild-type allele is located within 13q14-q21 and is approximately 63 kb in length. This allele, which encodes 5-hydroxytryptamine 2A receptor… »
This gene plays a role in neurotransmitter modulation and in chaperone activity. »
Definition: Human HTR3A wild-type allele is located in the vicinity of 11q23.1 and is approximately 15 kb in length. This allele, which… »
This gene plays a role in proteolysis. »
Human HTRA1 wild-type allele is located in the vicinity of 10q26.3 and is approximately 53 kb in length. This allele, which encodes… »
Human HTT wild-type allele is located in the vicinity of 4p16.3 and is approximately 199 kb in length. This allele, which encodes… »
A DNA-binding and thermostable low-molecular-weight E. coli protein that resembles eukaryotic histones. Acts as a cofactor in transcriptional repression. (from IRB… »
A recombinant protein consisting of the hu14.18 monoclonal antibody fused to the cytokine interleukin-2 (IL2) with potential antineoplastic activity. The monoclonal antibody… »
An anticancer drug in which hu14.18, a monoclonal antibody, is combined with interleukin-2. The monoclonal antibody binds to the cancer cells and… »
A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory… »
Anticuerpo monoclonal en estudio para el tratamiento de algunos tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
A traditional Chinese medicine (TCM) containing a water soluble Bufo toad skin extract that includes the cardiac glycosides bufalin, cinobufagin and resibufogenin… »
A monoclonal antibody being studied in the treatment of several types of cancer. Monoclonal antibodies are made in the laboratory and can… »
Anticuerpo monoclonal en estudio para el tratamiento de varios tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
A Chinese herb that has been used as a treatment for a variety of medical problems. It is being studied as an… »
Hierba china que se ha usado como tratamiento para una variedad de problemas médicos. Está en estudio para usarse como medicamento contra… »
An electronic device designed as a central connection for other devices. »
An immunoconjugate consisting of the anti-tumor cytokine interleukin-12 (IL-12) fused to the tumor-targeting antibody BC1 with potential immunostimulatory and antineoplastic activities. The… »
A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal antibody huC242 to… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. Se elabora al unir el anticuerpo monoclonal huC242 a una sustancia… »
An immunoconjugate comprised of a humanized monoclonal antibody with antitumor activity. The monoclonal antibody CC49 is developed from the murine monoclonal antibody… »
Ofrece información sobre la expresión de todos los genes y todas las variaciones genéticas de un individuo o un organismo. »
A monoclonal antibody that binds to the protein MUC1, which is found on breast, ovarian, pancreatic, gastric, and colon cancer cells. Monoclonal… »
Anticuerpo monoclonal que se une a la proteína MUC1, que se encuentra sobre las células cancerosas mamarias, ováricas, pancreáticas, gástricas y del… »
A monoclonal antibody being studied in the treatment of advanced multiple myeloma. Monoclonal antibodies are made in the laboratory and can locate… »
Anticuerpo monoclonal en estudio para el tratamiento del mieloma múltiple en estadio avanzado. Los anticuerpos monoclonales se producen en el laboratorio y… »
The bipedal primate mammal, Homo sapiens; belonging to man or mankind; pertaining to man or to the race of man; use of… »
A self-administered instrument designed to measure physical activity. The HAP was originally developed to measure quality of life achieved by patients in… »
The determination of the amount of the human albumin antibody in a sample. »
Human antibodies which recognize other human antibodies. These can develop in certain disease states or in response to treatment with therapeutic antibodies… »
Human antibodies which recognize mouse antibodies. These often develop in response to treatment with antibodies and limit the effectiveness of the… »
The determination of the amount of the human anti-mouse antibody in a sample. »
A human antibody which recognizes ricin epitopes. These antibodies often develop in response to treatment with immunotoxins that are comprised of ricin… »
The determination of the amount of human anti-sheep IgE antibody present in a sample. »
The determination of the amount of human anti-sheep IgG antibody present in a sample. »
The determination of the amount of human anti-sheep IgM antibody present in a sample. »
Interdisciplinary studies involving biology, anthropology, nutrition, and medicine with a focus on humans. »
The production of concentrated proteins from human plasma during a protein purification process. »
Body lice are tiny parasitic insects (Pediculus humanus corporis) that spread through close contact with other people. Body lice may be 2… »
The branch of pathology concerned with the cause, origin, and nature of human cancers. »
The process by which human donor cells or tissues are obtained for use in human implantation, transplantation, infusion, or transfer. »
A product that contains human cells or tissue. »
A sialoglycoprotein hormone secreted by the placenta and maintains the corpus luteum at the beginning of the gestation period. »
A laboratory test to detect the amount of human chorionic gonadotropin in a biospecimen. »
A structure found in the nucleus of human cells that is comprised of a strand of linearized double-stranded DNA plus proteins that… »
A section within the study document pertaining to data collected from human clinical study subjects. »
A thick, protein-rich substance secreted by the breasts during the second half of pregnancy and for a few days after birth before… »
A substance being studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part of the brain)… »
To replicate in host cell, viruses commandeer cellular signaling pathways. Cytomegalovirus (CMV) is a DNA virus that is widespread in the population… »
A site designated as an establishment for outsourcing of human drug compounding. »
A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer… »
A type of pluripotent stem cells derived from early stage human embryos, up to and including the blastocyst stage, that are capable… »
A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer… »
The determination of the amount of human epidermal growth factor receptor 2 present in a sample. »
Describes cancer cells that do not have a large amount of a protein called HER2 on their surface. In normal cells, HER2… »
Describes cancer cells that have too much of a protein called HER2 on their surface. In normal cells, HER2 helps to control… »
A laboratory test that measures the amount of HER2 protein on cancer cells or how many copies of the HER2 gene are… »
A protein found on cells that line the lungs and reproductive organs, such as the ovaries. Human epididymis protein 4 may be… »
Issue associated with the interaction and interfacing between devices and users in terms of users' abilities, expectations, and limitations with work environments… »
Any tissue from a human fetus. »
The branch of genetics focusing on human heredity. »
The total gene complement, about 3 billion base pairs of DNA, contained in the human chromosomes. »
An international organization of scientists involved in human genetics. Established in 1989 by a collection of the world's leading human geneticists, the… »
A coordinated international effort of researchers to map and sequence the human genome. »
The glandular kallikrein gene family comprises 25-30 homologous genes that encode specific proteases involved in the processing of biologically active peptides. … »
A vaccine consisting of a plasmid DNA encoding the human melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a… »
Small parasitic insects that can cause a itching red rash to the skin of the waist, shoulders, armpits, neck and pubic… »
A type of virus that causes herpes infections and has DNA as its genetic material. There are two types of human… »
HSV is a nuclear replicating, icosahedral, enveloped DNA virus. The HSV envelope contains at least 8 glycoproteins. The matrix or tegument which… »
A species of enveloped and spherical viruses with a capsid with T=16 icosahedral symmetry and surrounded by amorphous tegument, in the Herpesviridae… »
An icosahedral, enveloped virus containing a single molecule of linear double-stranded DNA of 125000 nucleotides that infects only humans. It is the… »
A species of enveloped and spherical viruses with a capsid with T=16 icosahedral symmetry and surrounded by amorphous tegument, in the Herpesviridae… »
A human herpesvirus that has been found in certain lymphoproliferative disorders, replicates in a number of different types of leukocytes, and is… »
A species of enveloped and spherical viruses with a capsid with T=16 icosahedral symmetry and surrounded by amorphous tegument, in the Herpesviridae… »
A type of virus that causes Kaposi sarcoma (a rare cancer in which lesions grow in the skin, lymph nodes, lining… »
The cause of acquired immunodeficiency syndrome (AIDS). Also called HIV. »
The type species of lentivirus and the etiologic agent of acquired immunodeficiency syndrome (AIDS). It is characterized by its cytopathic effect and… »
An HIV species related to HIV-1 but carrying different antigenic components and with differing nucleic acid composition. It shares serologic reactivity and… »
A synthetic peptide corresponding to the first 11 N-terminal amino acids of human lactoferrin (hLF1-11) with potential antimicrobial activity. Human lactoferrin, a… »
A type of molecule found on the surface of most cells in the body. Human leukocyte antigens play an important part in… »
A process in which blood or tissue samples are tested for human leukocyte antigens (HLAs). HLAs are molecules found on the surface… »
A type of molecule found on the surface of most cells in the body. Human lymphocyte antigens play an important part in… »
Follicle-Stimulating Hormone and Luteinizing Hormone excreted in the urine of post-menopausal women. »
An allogeneic human cytotoxic T-lymphocyte cell line (TALL-104) with potential antineoplastic activity. TALL-104 is an IL-2-dependent human leukemic T cell line, expressing… »
Movement of residence from one place to another. Includes nomadism; labor or seasonal migration; patterns of rural, urban, or suburban migration; or… »
A human monoclonal immunoglobulin M (IgM) antibody with potential antineoplastic activity. Human MOAB LICO 28a32 binds to the colon tumor-associated antigen… »
A naturally-occurring human IgM monoclonal antibody with potential antineoplastic activity. Human monoclonal antibody 216, derived from the gene VH4-34, binds to the… »
A human monoclonal antibody (B11) directed against the mannose receptor and linked to the beta-subunit of human chorionic gonadotropin (hCG beta) with… »
Early-to late-stage myeloid progenitor cells derived from adult human stem cells with potential hematopoietic activity. Upon infusion, human myeloid progenitor cells CLT-008… »
The process of distributing non-prescription medications for human use. »
The process of manufacturing non-prescription medications for humans by a pharmaceutical company. »
A vaccine formulation consisting of several types of human papillomavirus (HPV)-derived noninfectious virus-like particles (VLPs) with potential immunoprophylactic activity. Upon administration, HPV… »
A recombinant vaccine of different types of HPV proteins which are well-conserved within types with a significant inter-type variation. »
A type of virus that can cause abnormal tissue growth (for example, warts) and other changes to cells. Infection for a long… »
A peptide vaccine consisting of amino acids 12 through 20 of the viral oncoprotein human papillomavirus (HPV) 16 E7. Vaccination with HPV-16… »
A synthetic agent derived from human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related… »
A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with… »
A laboratory test in which cells are scraped from the cervix to look for DNA of human papillomaviruses (HPV). HPV can cause… »
A squamous cell carcinoma associated with human papilloma type 16 virus, arising from the oropharynx. »
A laboratory test in which cells are scraped from the cervix to look for RNA of the most common types of human… »
A laboratory test in which cells are tested for DNA or RNA from certain types of human papillomavirus (HPV) that are known… »
A vaccinia viral based vaccine, encoding epitopes of E6 and E7 proteins from human papillomavirus (HPV) types 16 and 18, with immunostimulatory… »
A vaccine used to prevent genital warts, anal cancer, cervical cancer, vulvar cancer, and vaginal cancer caused by certain types of human… »
A vaccine consisting of noninfectious, recombinant virus-like particles (VLP) containing the major viral capsid protein L1 of nine strains of human papillomavirus… »
A human papillomavirus that is a common causative agent of genital warts. Human papillomavirus-11 is considered low-risk for causing malignancies. »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
Genital warts caused by HPV 6 and 11 are the most common STD in the United States. Over a million cases are… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
A virus comprised of a protein coat (capsid) surrounding a circular, double-stranded DNA organized into coding and non-coding regions, which can induce… »
An adenosquamous carcinoma associated with the presence of human papillomavirus infection. »
An anal squamous cell carcinoma related to infection with sexually transmittable human papillomavirus. »
A carcinoma that arises from the cervix and is caused by human papillomavirus infection. »
A cervical squamous cell carcinoma associated with human papilloma virus infection. Histologic variants include papillary carcinoma, warty carcinoma, and squamotransitional carcinoma. … »
An endocervical adenocarcinoma that is caused by human papillomavirus infection. »
An esophageal squamous cell carcinoma that arises from squamous epithelial cells infected with human papillomavirus. »
A malignant neoplasm caused by human papillomavirus in an a patient with a history of AIDS. »
A squamous cell carcinoma that arises from the penis and is caused by human papillomavirus infection. Morphologic variants include basaloid carcinoma… »
A squamous cell carcinoma that arises from the vulva and is caused by human papillomavirus infection. »
A single-stranded, negative-sense RNA virus of the paramyxovirus group that causes croup in children. »
The serotype labeled 2 of the viral species Human parainfluenza virus, which is a single-stranded, negative-sense RNA virus of the Paramyxoviridae family… »
The serotype labeled 3 of the viral species Human parainfluenza virus, which is a single-stranded, negative-sense RNA virus of the Paramyxoviridae family… »
The serotype labeled 4 of the viral species Human parainfluenza virus, which is a single-stranded, negative-sense RNA virus of the Paramyxoviridae family… »
Laws set by the U.S. Department of Health and Human Services (DHHS) to protect a person from risks in research studies that… »
Branch of medicine concerned with the cause, origin, and nature of human disease, including the changes occurring as a result of… »
The Human Pharmacology Study is a clinical study that involves one or more of following activities: assesses tolerance to the agent, defines/describes… »
The process of distributing prescription medications for human use. »
The process of manufacturing prescription medications for humans by a pharmaceutical company. »
A vaccine consisting of a plasmid DNA encoding the human prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic… »
A negative-sense, enveloped RNA virus. The virion is variable in shape and size with an average diameter of between 120 and 300… »
An immunoglobulin blood product given to the pregnant mother that helps to prevent the Rh negative mother from developing an antibody response… »
A living individual about whom an investigator conducting research obtains data through intervention or interaction with the individual or through identifiable private… »
A study that has gone beyond the laboratory research and the testing that can be done with experimental animals, and needs to… »
A type of virus that infects T cells (a type of white blood cell) and can cause leukemia and lymphoma. Human T-cell… »
A type of virus that infects T cells (a type of white blood cell) and can cause leukemia and lymphoma. Human T-cell… »
A partially purified preparation isolated from the thymus and containing several peptides. Human Thymosin-Fraction 5 (TF-5) possesses immunopotentiating properties and can correct… »
An oral rinse solution containing a strain of the bacteria Lactococcus lactis (L. lactis) genetically modified to express human Trefoil Factor 1… »
Catalog of genes expressed in cells at various stages of tumor development. hGTI is part of CGAP. (Bypass Budget) »
Viruses which routinely infect humans »
A premarket submission to FDA for a device intended to benefit patients by treating or diagnosing a condition affecting fewer than 4,000… »
A type of antibody made in the laboratory by combining a human antibody with a small part of a mouse or rat… »
A substance being studied in the treatment of some types of cancer and other conditions. Humanized monoclonal antibody MEDI-522 binds to a… »
Human androgen receptor gene assay. This assay was used to detect X chromosomal inactivation for diagnosis of X-linked conditions, ie. Kennedy… »
A drug used to treat chronic lymphocytic leukemia (CLL) that has not gotten better with other chemotherapy. It is also being studied… »
Medicamento que se usa para tratar la leucemia linfocítica crónica (LLC) que no mejoró con otro tratamiento de quimioterapia. También está en… »
A traumatic or pathologic injury to the humerus in which the continuity of the humerus is broken. »
Aparato que humedece el aire. »
A machine that puts moisture in the air. »
A device designed to add moisture to the air. »
A feeling of extreme embarrassment. »
Humo que proviene del extremo encendido de un producto de tabaco en combustión, como un cigarrillo, una pipa o un cigarro. El… »
Humo de tabaco que exhalan los fumadores. El humo de la corriente principal puede ser una forma de humo de tabaco en… »
Humo producido al quemarse un producto de tabaco y humo exhalado por los fumadores. La inhalación del humo de tabaco ambiental se… »
A type of therapy that uses humor to help relieve pain and stress and improve a person’s sense of well-being. It may… »
Sustancia trasparente parecida a la gelatina que llena el interior del globo ocular. En la medida que una persona envejece, el humor… »
Immune processes mediated by antibodies »
A concentration unit expressed as a number or quantity of objects in hundred billions per unit of volume equal to one… »
A unit of cell count expressed in hundreds of millions. »
A concentration unit expressed as a number or quantity of objects in hundred millions per unit of volume equal to one… »
A measure of viable infectious entities expressed in hundreds of millions in the specimen or product defined as the smallest quantity that… »
A derived unit expressed as a number of cells in hundreds of thousands per unit of mass equal to one kilogram. … »
A unit of measurement equal to one hundred thousand entities per unit of area equal to one high powered field. »
A concentration unit expressed as a number or quantity of objects in hundred thousands per unit of volume equal to one… »
An X-linked, inherited lysosomal storage disease caused by the deficiency of the enzyme iduronate sulfatase that is responsible for the degradation of… »
Huntingtin (3144 aa, ~348 kDa) is encoded by the human HTT gene. This protein may be involved in the regulation of vesicular… »
Huntingtin-interacting protein 1 (1037 aa, ~116 kDa) is encoded by the human HIP1 gene. This protein plays a role in both clathrin-coat… »
A progressive hereditary neurodegenerative disorder inherited in an autosomal dominant fashion. Symptoms may appear at any age and include uncontrolled movements, clumsiness,… »
Huntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). HD is caused by a CAG… »
The Huntsman Cancer Institute at the University of Utah has a mission to understand cancer from its beginnings, to use that knowledge… »
Un huracán es una forma intensa de tormenta tropical. Los huracanes producen vientos fuertes, lluvias abundantes y tormentas eléctricas. Los… »
An autosomal recessive inherited disorder of mucopolysaccharide metabolism. It is the most severe form of mucopolysaccharidosis type I. It is characterized by… »
A hurricane is a severe type of tropical storm. Hurricanes produce high winds, heavy rains and thunderstorms. Hurricanes can cause… »
An uncommon type of thyroid tumor that can be benign or malignant. »
A sensation of discomfort or distress that is very unpleasant. »
Tipo de virus que causa infecciones por herpes y que tiene ADN como material genético. Hay dos tipos de HVH. Las infecciones… »
Tipo de virus que causa infecciones por herpes y que tiene ADN como material genético. Hay dos tipos de HVS. Las infecciones… »
The deposition of hyaline material in the wall of the arterioles. »
The determination of the amount of hyaline casts present in a urine sample. »
A serious disorder affecting newborns, particularly premature infants. It is caused by deficiency of surfactant, resulting in the formation of a membrane… »
A process of tissue replacement where the tissue is being replaced by hyaline or the tissue has degenerated to hyaline. »
Replacement of tissue stromal elements by hyaline material. »
Inflammatory intraocular reaction with clouding and cells in vitreous; often accompanies inflammation of ciliary body, iris, choroid, or retina. »
Hyaluronan synthase 2 (552 aa, ~64 kDa) is encoded by the human HAS2 gene. This protein plays a role in the biosynthesis… »
Encoded by human HMMR Gene and expressed in normal breast tissue, the 724-amino acid 84 kD Hyaluronan-Mediated Motility Receptor is similar to… »
A glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that is a component of connective tissue, skin, vitreous humour, umbilical cord,… »
Hyaluronic Acid Binding involves a biophysical interaction between a biological molecule, such as a protein, and hyaluronic acid, a linear glycosaminoglycan of… »
The determination of the amount of hyaluronic acid present in a sample. »
A clear, colorless water-based vaginal gel containing the partial benzyl ester of hyaluronic acid (HA) with potential hydrating activity. Upon vaginal application,… »
An injectable enzyme with potential adjuvant activity. Upon subcutaneous administration, hyaluronidase modifies the permeability of connective tissue by hydrolyzing hyaluronic acid. This… »
A highly purified preparation of ovine testicular hyaluronidase with potential chemoadjuvant activity. Upon subcutaneous administration, hyaluronidase modifies the permeability of connective tissue… »
A second generation synthetic oligonucleotide with immunomodulatory and potential antineoplastic activities. HYB2055 consists of unmethylated CpG dinucleotide motifs that are present abundantly… »
An electronic device containing circuits of different technological types. »
A tooth restorative material that contains both microfill composites and macrofill composites, and contains a range of particle sizes between .6 and… »
Use of a common bed for 2 imaging modalities implemented at or near the same time. »
The integration of both discrete and continuum modeling techniques in representing distinct dynamics and topographic regions of a system. »
A molecular biology device that utilizes a set of defined oligonucleotide probes, recombinant clones, or other samples attached in a specific grid… »
A tumor of hybrid cells used in the in vitro production of specific monoclonal antibodies; produced by fusion of an established tissue… »
A drug used to treat certain types of ovarian cancer, lung cancer, and cervical cancer. Hycamtin is a type of topoisomerase… »
Medicamento usado para tratar ciertos tipos de cáncer de ovario, de pulmón y de cuello uterino. Hycamtin es un tipo de inhibidor… »
A thioxanthene derivative of lucanthone with anti-schistosomal activity and potential antineoplastic activity. Hycanthone interferes with parasite nerve function, resulting in parasite paralysis… »
A cyst that is attached to the fallopian tube and originates from the remnants of the Mullerian duct. »
A cystic remnant of the Mullerian duct attached to the tunica vaginalis on the superior testis in males and the fimbriated end… »
A slow-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta)… »
The oil pressed from the seeds of the Chaulmoogra tree. Hydnocarpus seed oil is used for its antibacterial properties in the treatment… »
A hydrazinopyridazine-based diuretic with antihypertensive activity. Hydracarbazine is no longer marketed. »
A phthalazine derivative with antihypertensive effects. Hydralazine exerts its vasodilatory effects through modification of the contractile state of arterial vascular smooth muscle… »
The hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release and interferes with… »
A rare congenital brain disorder in which the cerebral hemispheres are absent and replaced by sacs that contain cerebrospinal fluid. Signs and… »
The process of combining with water. In medicine, the process of giving fluids needed by the body. »
A bed that includes a hydraulic system designed for movement or positioning of an object or subject. »
A system designed to use fluid pressure to bring about movement. »
A highly reactive base and reducing agent used in many industrial and medical applications. In biological applications, hydrazine and its derivatives… »
A substance that has been studied as a treatment for cancer and as a treatment for cachexia (body wasting) associated with advanced… »
A colorless, crystalline compound that emits toxic fumes of nitrogen oxides when heated to decomposition. Hydrazobenzene has been used primarily in the… »
A drug used to treat chronic myelogenous leukemia (CML) that has not gotten better with other treatment. It is also used with… »
A rare skin disorder of unknown etiology affecting children. It is a photodermatitis, characterized by the formation of vesicles and scarring on… »
A rare, EBV-positive primary cutaneous T-cell lymphoma, composed of CD8 positive cytotoxic T-lymphocytes. It is considered a variant of nasal type… »
A thiazide derivative, also known as dihydrobenzthiazide, and carbonic anhydrase inhibitor, with antihypertensive activity. »
A substance made of only hydrogen and carbon. Examples of hydrocarbons are coal, petroleum, natural gas and tar. They are used as… »
Hydrocarbons containing multiple halogen substituents (Br, Cl, Fl, I). »
The abnormal buildup of cerebrospinal fluid in the ventricles of the brain. »
A salt that is comprised of a hydrogen and chloride ion that can be linked to a base form of a drug… »
A short acting thiazide diuretic. Hydrochlorothiazide (HCTZ) is widely used to treat hypertension and edema. This agent's metabolite appears to preferentially bind… »
A combination drug containing hydrochlorothiazide and triamterene used as a diuretic. »
A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor… »
A drug used to treat moderate to severe pain and cough. Hydrocodone bitartrate is made from codeine and binds to opioid receptors… »
The determination of the amount of hydrocodone present in a sample. »
A combination preparation of the analgesic acetaminophen and the semisynthetic opioid agonist hydrocodone with analgesic and antitussive activities. Acetaminophen exerts its analgesic… »
A drug used to relieve the symptoms of certain hormone shortages and to suppress an immune response. »
The synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid… »
The butyrate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the… »
The synthetic hemisuccinate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid… »
The probutate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the… »
The sodium salt of hydrocortisone succinate with glucocorticoid property. Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory… »
The valerate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the… »
Hydrocortisone used as a placebo in comparative studies. »
An intermediate-acting benzothiadiazine sulfonamide derivative belonging to the class of the thiazide diuretics. »
The physical association between an electronegative atom and a hydrogen atom that is directly bound to a second, relatively electronegative atom. … »
A liquid or gas form of cyanide. Cyanide is a poisonous chemical found in some foods and plants, tobacco smoke, and when… »
The determination of the amount of hydrogen present in a sample. »
A chemical used in bleaches, dyes, cleansers, antiseptics, and disinfectants. In a concentrated form, it is toxic and irritating to tissues. … »
A sterilization process that uses hydrogen peroxide to kill microorganisms. »
A wax-like hydrogenated derivative of castor oil. Hydrogenated castor oil has many industrial applications. »
A hydrogenated derivative of palm oil. Hydrogenated palm oil has industrial applications. »
A hydrogenated derivative of soybean oil. Hydrogenated soybean oil has a thicker consistency than standard soybean oil and is used as a… »
Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage; e.g., esterases, phosphatases, nucleases, peptidases. SYN hydrolyzing… »
A gene that encodes an enzyme capable of catalyzing the hydrolysis of chemical bonds. »
A chemical reaction that uses water to break down a compound. »
A class of tannins composed of phenolic acids connected to a central core sugar (typically D-glucose). »
The hydrogenated ketone of morphine, a semi-synthetic opioid with analgesic effects. Hydromorphone selectively binds the mu-opioid receptor which is linked through… »
A drug used to treat moderate to severe pain. It may also be used to treat certain types of cough. Hydromorphone hydrochloride… »
The determination of the amount of hydromorphone present in a sample. »
Abnormal enlargement of a kidney, which may be caused by blockage of the ureter (such as by a kidney stone) or chronic… »
The faces of the lipid bilayer that are exposed to the cytoplasm and extracellular space. It is comprised of the hydrophilic heads… »
The inherent characteristic of a molecule or substance to be soluble in water. »
The inner part of the lipid bilayer that is comprised of the hydrophobic tails of the lipid components and the membrane spanning… »
The inherent characteristic of a molecule or substance to be immiscible in water. The property means that the moiety of interest does… »
A condition characterized by fluid accumulation in two or more anatomic compartments in the fetus. »
Produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and… »
A drug used to treat moderate to severe pain. It may also be used to treat certain types of cough. Hydrostat IR… »
Medicamento que se usa para aliviar el dolor grave o moderado. También se puede usar para tratar ciertos tipos de tos. Hydrostat… »
Abnormal enlargement of the ureter caused by any blockage that prevents urine from draining into the bladder. »
A group of weak acids with the general chemical formula RC(=O)N(R')OH and antineoplastic and antimicrobial activities. Hydroxamic acids covalently bind to… »
A serotonin antagonist and diuretic agent. Hydroxyindasate was never marketed. »
An indirect-acting sympathomimetic amine with adrenergic property. Hydroxyamphetamine, when applied topically to the eye, stimulates the release of norepinephrine from postganglionic adrenergic… »
The hydrobromide salt form of hydroxyamphetamine, an indirect-acting sympathomimetic amine with adrenergic properties. Hydroxyamphetamine, when applied topically to the eye, stimulates the… »
A class of organic compounds with a carboxyl group (-COOH) and at least one hydroxyl group attached to a phenyl ring. The… »
A substance that decreases immune responses in the body. It is used to treat some autoimmune diseases, and is being studied as… »
A synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae)… »
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of… »
The monovalent group -OH in such compounds as bases and some acids and alcohols. »
A monovalent radical consisting of one hydrogen and oxygen atom found in bases, carboxylic acids, and alcohols. »
A substance that blocks an enzyme needed by the body to make cholesterol and lowers the amount of cholesterol in the… »
A physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone… »
A synthetic progestational agent similar to the endogenous progesterone used in hormone therapy or as a female contraceptive. Mimicking the action of… »
The determination of the amount of hydroxyproline present in a sample. »
A semisynthetic, high viscosity polymer used as a food additive which may have the ability to lower total cholesterol and low-density lipoprotein… »
Any substance that inhibits hydroxysteroid dehydrogenase, an enzyme that catalyzes the interconversion of hydroxyl and carboxyl groups on steroids, leading to activation… »
A cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to DNA and RNA in a non-intercalating… »
The isethionate salt form of hydroxystilbamidine, a cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to… »
A long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels. … »
An anticancer drug that belongs to the family of drugs called antimetabolites. »
A piperazine derivative with antihistamine, antiemetic, and anxiolytic properties. Hydroxyzine's antihistaminic effect is due to its metabolite, cetirizine, a potent H1 receptor… »
The hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks… »
The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine pamoate… »
The science of health, and the practice of cleanliness that promotes good health and well-being. »
A parasitic infection caused by tapeworms. Most infected individuals do not have symptoms. When symptoms appear, they include diarrhea, abdominal pain, restlessness,… »
A short elastic band that unites the epiglottis to the upper border of the hyoid bone. »
A muscle extending from the hyoid bone to the side of the tongue that retracts and pulls the side of the tongue… »
A U-shaped bone supporting the tongue. This bone is located at the base of the tongue and is suspended from the tips… »
A belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits… »
The sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or… »
This gene plays in the regulation of cellular response to ischemic stress conditions. »
Human HYOU1 wild-type allele is located within 11q23.1-q23.3 and is approximately 13 kb in length. This allele, which encodes 150 kDa oxygen-regulated… »
The portion of the right main bronchus that is below the right pulmonary artery. »
An abbreviation for a chemotherapy combination used to treat some types of acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL). Hyper-CVAD includes… »
An abbreviation for a chemotherapy combination used to treat some types of acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL). Hyper-CVAD regimen… »
A higher than normal level of activity. Hyperactivity can be used to describe the increased action of a body function, such as… »
Abnormally high levels of aldosterone in the blood. »
Overproduction of aldosterone by the adrenal glands, which may lead to hypokalemia and/or hypernatremia. »
An increased sensation to painful stimuli that may follow damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve. Hyperalgesia… »
A form of nutrition that is delivered into a vein. Hyperalimentation does not use the digestive system. It may be given to… »
A laboratory test result indicating increased levels of ammonia in the blood. »
A rare autosomal recessive disorder characterized by abnormalities in the urea cycle. It is caused by deficiency of the enzyme arginase, resulting… »
Oxygen that is given at a pressure that is higher than the pressure of the atmosphere at sea level. In medicine, breathing… »
The use of a pressurized chamber for the delivery of oxygen in higher concentrations for therapeutic benefit. Useful in the treatment of… »
Higher-than-normal amount of bilirubin in the blood. Bilirubin is a substance formed when red blood cells break down. »
Higher than normal levels of calcium in the blood. Some types of cancer increase the risk of hypercalcemia. »
Hypercalcemia generally develops as a late complication of malignancy; its appearance has grave prognostic significance. It remains unclear, however, whether death is… »
A laboratory test result indicating an increased amount of cholesterol in the blood. »
A morphologic finding referring to the presence of darkly stained nuclei due to abundance of DNA on hematoxylin-eosin stained sections. It… »
The determination of the prevalence of erthrocytes with an elevated hemoglobin concentration. »
Abnormally high level of cortisol in the blood. »
A regimen consisting of cyclophosphamide, vincristine, doxorubicin and dexamethasone, administered on a hyperfractionated schedule, used to treat adult L3 acute lymphoblastic leukemia… »
A regimen consisting of cyclophosphamide, vincristine, doxorubicin and dexamethasone (Hyper-CVAD) administered on a hyperfractionated schedule, followed by high dose methotrexate and cytarabine,… »
A B-cell acute leukemia characterized by the presence of lymphoblasts which contain more than 50 and usually less than 66 chromosomes. It… »
A chromosomal abnormality in which the chromosomal number is greater than the normal diploid number. »
A pathologically high percentage of blood that is forced from the heart ventricle to produce cardiac output. This is often the result… »
A radiologic finding describing a region in an image with a signal higher than that of the surrounding regions. »
A radiologic finding describing thin lines in an image with a signal higher than that of the surrounding tissue. »
Severe, intractable vomiting during pregnancy (usually the first trimester) accompanied by dehydration, weight loss, and electrolyte imbalances. »
A syndrome characterized by persistent eosinophilia, for which no underlying cause can be found, and which is associated with signs of organ… »
Abnormally high level of estrogen. »
A finding indicating that joints, muscles, and/or tendons can extend beyond their normal limit. »
Radiation treatment in which the total dose of radiation is divided into small doses and treatments are given more than once a… »
Radiation treatment in which the total dose of radiation is divided into small doses and treatments are given more than once a… »
An excess of GAMMA-GLOBULINS in the blood. It is seen frequently in chronic infectious diseases. (Dorland, 27th ed) »
Abnormally high levels of glucagon in the blood, which may manifest as hyperglycemia and/or necrolytic migratory erythema. »
Higher than normal amount of glucose (a type of sugar) in the blood. Hyperglycemia can be a sign of diabetes or other… »
An imaging artifact resulting from hyperglycemia of the patient. »
Ovarian or testicular dysfunction associated with high levels of gonadotropins. »
A disorder characterized by excessive perspiration. »
A serious metabolic condition caused by mutations in the MTHFR gene, medications, or nutritional deficiency. It results in increased levels of homocysteine… »
An anthraquinone derivative that is naturally found in the yellow flower of Hypericum perforatum (St. John's wort) with antidepressant, potential antiviral, antineoplastic… »
An oil obtained by infusing hypericum flowers into a carrier oil. Hypericum oil has antiseptic and analgesic properties. »
An herbal product sold as an over-the-counter treatment for depression. It is being studied for its ability to lessen certain side effects… »
Producto herbario que se vende sin receta médica como tratamiento para la depresión. Está en estudio por su capacidad de disminuir ciertos… »
A dietary supplement consisting of bovine colostrum, containing high titers of immunoglobulins (Igs), with immunostimulating and anti-infective activities. Hyperimmune bovine colostrum is… »
A disorder of neutrophils characterized by the presence of abnormal or absent chemotactic responses and hyperimmunoglobulinemia E. It is transmitted as an… »
An immunodeficiency state characterized by very low serum IgG and IgA but either a normal or, more frequently, a markedly elevated concentration… »
Abnormally high levels of insulin in the blood. »
Higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic… »
A condition marked by thickening of the outer layer of the skin, which is made of keratin (a tough, protective protein). It… »
A reference (link) from some point in one hypertext document to another document, another place in the same document, or a… »
Elevated levels of lipids in the blood. »
Metabolic disease characterized by excess plasma LIPOPROTEINS. »
A genetic disorder of lipoprotein metabolism caused by mutations in the LPL and apolipoprotein (apo) C-II genes. It is characterized by increased… »
A disorder of lipoprotein metabolism characterized by high levels of cholesterol and triglycerides in the blood. It is caused by elevation of… »
Higher than normal levels of magnesium in the circulating blood. »
A computer environment in which multiple linkages enable users to move directly from one segment of audio, video, graphic, or text to… »
Hypermethylation appears to be a controlled, epigenetic, heritable, and aberrant DNA methylation reaction on gene promoter regions and CpG islands associated with… »
Higher than normal levels of sodium in the circulating blood. »
Dehydration resulting from abnormally high levels of sodium in the blood. Infants and individuals that are intubated are at highest risk. … »
The most common type of kidney cancer. It begins in the lining of the renal tubules in the kidney. The renal tubules… »
Contact of a tooth or restoration such that it encrouches on the interocclusal freeway space. »
Increase in the mass of bone per unit volume. »
A condition of unknown etiology characterized by thickening of the inner table of the frontal bone of the skull. It is seen… »
A morphologic finding indicating increased keratin formation, preservation of the nuclei in the superficial cells, and absence of the stratum granulosum in… »
A condition in which the parathyroid gland (one of four pea-sized organs found on the thyroid) makes too much parathyroid hormone. This… »
An autosomal dominant inherited syndrome characterized by the development of parathyroid adenoma or carcinoma, ossifying fibroma of the mandible and maxilla, renal… »
An abnormal increase in the number of normal cells in an organ or tissue. »
An increase in parenchymal cell number. »
An increase in any epithelial cells of the mammary gland. »
Hyperplasia as an increase in glandular/stromal tissue compared to age matched wild type control mice. »
Increase in number of cells without atypia. »
A polyp found mainly in the stomach and colon. Microscopically, it is characterized by elongated, serrated crypts lined by proliferative… »
A chromosomal abnormality in that is characterized by an addition of chromosomes that results in a chromosome number that is not an… »
Abnormally high level of progesterone. »
Abnormally high level of prolactin in the blood. »
Extreme elevation of body temperature above normal. »
The determination of the number of hypersegmented neutrophils present in a sample. »
An exaggerated response by the immune system to a drug or other substance. »
Condition characterized by splenomegaly, some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone… »
Abnormal increase in the interorbital distance due to overdevelopment of the lesser wings of the sphenoid. »
A blood pressure of 140/90 or higher. Hypertension usually has no symptoms. It can harm the arteries and cause an increase in… »
A hypertensive disorder that develops during pregnancy. »
Abnormal enlargement of the heart resulting from long-standing hypertension. »
Brain dysfunction or damage resulting from MALIGNANT HYPERTENSION, usually associated with a diastolic blood pressure in excess of 125 mmHg. Clinical manifestations… »
Abnormally high body temperature. This may be caused as part of treatment, by an infection, or by exposure to heat. »
A type of treatment in which body tissue is exposed to high temperatures to damage and kill cancer cells or to make… »
A type of treatment in which body tissue is exposed to high temperatures to damage and kill cancer cells or to make… »
A procedure performed in combination with abdominal surgery for cancer that has spread to the abdomen. It involves the infusion of a… »
A procedure in which a warmed solution containing anticancer drugs is used to bathe, or is passed through the blood vessels of,… »
Too much thyroid hormone. Symptoms include weight loss, chest pain, cramps, diarrhea, and nervousness. Also called overactive thyroid. »
A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. »
Any solution of sodium chloride (NaCl) in water with a concentration of NaCl higher than that found in physiological saline (0.9%… »
Excessive hair growth anywhere on the body. »
A laboratory test result indicating elevated triglyceride concentration in the blood. »
A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with… »
Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the… »
A form of lichen planus that is characterized by plaques of markedly thickened skin that is often extremely pruritic and localized to… »
An abnormality characterized by thickening of the muscle in the wall of the pylorus. It results in the narrowing of the pyloric… »
A permanent mark on the skin caused by deposits of excessive amounts of collagen during wound healing. It is elevated and does… »
Abnormal enlargement of a body part or organ. »
Vertical strabismus in which there is permanent upward deviation of the visual axis of one eye. »
A buildup of uric acid (a byproduct of metabolism) in the blood. Hyperuricemia is a side effect of some anticancer drugs. … »
Having a large number of blood vessels. »
Abnormally prolonged, rapid, and deep breathing. »
An unique natural method of childbirth that is supported by a relaxing self-hypnosis method. »
A trance-like state in which a person becomes more aware and focused on particular thoughts, feelings, images, sensations, or behaviors. While under… »
Therapeutic use of hypnotism. It has been used to treat phobias and anxiety, to manage pain, and to extinguish habits and… »
A disorder characterized by a recurrent or persistent lack of desire for sexual activity. The lack of sexual desire is not attributable… »
An abnormally decreased sensitivity to touch, pressure, or pain. »
An abnormally low blood level of albumin. »
Abnormally low levels of aldosterone in the blood. »
A metabolic disorder characterized by deficiency of high density (alpha) lipoprotein in the blood. »
Lower than normal levels of calcium in the circulating blood. »
A laboratory finding indicating decreased number of hematopoietic cells in the bone marrow. It may result from decreased proliferation of all or… »
A morphologic finding indicating the presence of a small population of cells in a tissue sample. »
Preoccupation with the fear of having, or the idea that one has, a serious disease based on the person's misinterpretation of bodily… »
An anemic condition which results from a lack hemoglobin within erythrocytes. »
Anemia caused by the reduction of hemoglobin in relation to the red cell volume. As a result, the red cells have an… »
Abnormally low level of cortisol in the blood. »
A slender, hollow needle used for injection or aspiration. »
A tablet dissolved in solvent and intended for administration by hypodermic injection. »
A B-cell acute leukemia characterized by the presence of lymphoblasts which contain less than 46 chromosomes. It occurs in both children and… »
A chromosomal abnormality in which the chromosomal number is less than the normal diploid number. »
A radiologic finding describing a region in an image with a signal lower than that of the surrounding regions. »
Impairment of tactile sensitivity manifesting as partial loss of sensitivity to sensory stimuli. »
A blood coagulation disorder characterized by low levels of fibrinogen in the blood, resulting in bleeding. »
Radiation treatment in which the total dose of radiation is divided into large doses and treatments are given less than once… »
Radiation treatment in which the total dose of radiation is divided into large doses and treatments are given less than once… »
A condition in which the level of immunoglobulins (antibodies) in the blood is low and the risk of infection is high. … »
Either of two (inferior or superior) hypogastric nerve plexi in the lower abdomen. »
The lowest central region of the abdomen, below the umbilical region and between the two iliac regions. »
The twelfth cranial nerve. It arises from the hypoglossal nucleus and leads to the tongue. »
A non-neoplastic or neoplastic disorder affecting the hypoglossal nerve (twelfth cranial nerve). »
A triangular area containing the hypoglossal nucleus on either side of the dorsal median sulcus and superior to the vagal triangle. … »
Abnormally low blood sugar. »
A disorder characterized by decreased function of the gonads. Clinical manifestations in both males and females include poor libido, infertility, and… »
Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis. »
A term that refers to the presence of diminished numbers of cytoplasmic granules in myeloid cells. »
Reduced sweating. Causes include burns, dehydration, radiation, and leprosy. »
Lower than normal levels of potassium in the circulating blood. »
An autosomal dominant inherited or genetic disorder characterized by irregular episodes of muscle weakness or paralysis which are always accompanied by low… »
Lower-than-normal amount of magnesium in the blood. »
A less severe form of mania characterized by elevated mood, hyperactivity, and grandiosity. In contrast to mania, these symptoms do not cause… »
A rare genetic syndrome with an autosomal recessive pattern of inheritance. It is caused by a mutation in the ESCO2 gene. Clinical… »
Lower-than-normal amount of sodium in the blood. »
An endocrine disorder characterized by decreased production of parathyroid hormone by the parathyroid glands. It is usually caused by damage of the… »
The portion of the aryepiglottic fold in the area where the larynx and esophagus join. »
Cancer that forms in tissues of the hypopharynx (the bottom part of the throat). The most common type is squamous cell carcinoma… »
A clinical finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as… »
A clinical finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system. … »
A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v6 classification system as… »
A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as… »
A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v6 classification system as… »
A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system as… »
hypopharyngeal cancer, following the rules of the TNM classification system as they pertain to staging of regional lymph nodes. »
A pathologic finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v6 classification system. … »
A finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v6 classification system. »
A finding about one or more characteristics of hypopharyngeal cancer, following the rules of the TNM AJCC v7 classification system. »
Carcinoma, predominantly squamous cell, arising from the epithelial cells of the hypopharynx. »
A term that refers to the staging of hypopharyngeal carcinoma according to the American Joint Committee on Cancer, 6th edition. »
A term that refers to the staging of hypopharyngeal carcinoma according to the American Joint Committee on Cancer, 7th edition. »
A benign or malignant neoplasm that affects the hypopharynx. »
A squamous cell carcinoma arising from the hypopharynx. Signs and symptoms include dysphagia, hemoptysis, and the presence of a neck… »
The bottom part of the throat. Cancer of the hypopharynx is also known as hypopharyngeal cancer. »
A rare, serious metabolic disorder caused by mutations in the gene encoding tissue non-specific alkaline phosphatase (TNSALP) activity. It is characterized by… »
Lower-than-normal amount of phosphorus in the blood. »
The blood vessel that drains blood from the capillary beds between the hypothalamus and anterior pituitary. »
Surgical removal of part or all of the pituitary gland. »
A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from… »
A mammary gland that did extend into the fat pad but not completely or did not respond to lactogenic hormones. »
Hypoplasia refers to inadequate development or underdevelopment of an organ. The prostate should be small for age and may or may not… »
A rare congenital cardiovascular disorder characterized by severe underdevelopment of the left side of the heart. Signs and symptoms include tachypnea, cyanosis,… »
A rare congenital cardiovascular disorder characterized by severe underdevelopment of the right side of the heart. The infants develop cyanosis shortly after… »
Abnormally low level of progesterone. »
A laboratory test result indicating abnormally low levels of total protein in the serum. »
A birth defect in which the opening of the urethra (the tube through which urine leaves the body) is not in its… »
Abnormally low blood pressure. »
A tumor characterized by the presence of mature ganglion cells and neuronal differentiation, arising in the hypothalamus. It is often associated with… »
Releasing and inhibiting hormones secreted by the neurosecretory neurons of the hypothalamus binding to the receptors of the anterior pituitary cells and… »
Benign and malignant tumors of the HYPOTHALAMUS. Pilocytic astrocytomas and hamartomas are relatively frequent histologic types. Neoplasms of the hypothalamus frequently originate… »
A system of vessels between the hypothalamus and anterior pituitary in which blood, after passing through one capillary bed, is conveyed through… »
The area of the brain that controls body temperature, hunger, and thirst. »
Abnormally low body temperature. »
A tentative proposal made to explain certain observations or facts that requires further investigation to be verified. »
Hypothetical protein LOC145788 (121 aa, ~14 kDa) is encoded by the human FLJ27352 gene. This protein has no known function. »
Too little thyroid hormone. Symptoms include weight gain, constipation, dry skin, and sensitivity to the cold. Also called underactive thyroid. »
A condition of decreased tone of the skeletal muscles and diminished resistance to passive stretching. »
A congenital condition, usually due to genetic aberrations, that is characterized by a lack of hair growth on the head and/or… »
A state in which there is a reduced amount of air entering the pulmonary alveoli. »
Abnormally decreased volume of circulating fluid (plasma) in body. »
Shock resulting from insufficient blood volume for the maintenance of adequate cardiac output, blood pressure and tissue perfusion. »
A purine-based organic compound in human muscle tissues, Hypoxanthine is formed during purine catabolism as a product of xanthine oxidase action on… »
Cytoplasmic Hypoxanthine Phosphoribosyltransferases (Purine/Pyrimidine Phosphoribosyltransferase Family) catalyze the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or 6-mercaptopurine to the corresponding 5'-mononucleotides and… »
Hypoxanthine-guanine phosphoribosyltransferase (218 aa, ~25 kDa) is encoded by the human HPRT1 gene. This protein plays a role in nucleoside metabolism. … »
A condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia… »
Hypoxic stress, like DNA damage, induces p53 protein accumulation and p53-dependent apoptosis in oncogenically transformed cells. Unlike DNA damage, hypoxia does not… »
Highly expressed in secretory tissues (liver and pancreas) by human HYOU1 Gene (HSP70 Family), hypoxia-induced 999-aa (precursor) 150 kD Hypoxia Up-Regulated 1… »
A proprietary, hypoxia-activated prodrug with potential antineoplastic activity. Upon administration, the hypoxia-activated prodrug PR610 is activated in the hypoxic cells within tumors… »
A hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as… »
Hypoxia-inducible factor 1-alpha (826 aa, ~93 kDa) is encoded by the human HIF1A gene. This protein plays a role in transcriptional regulation… »
Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 tension caused by hypoxia/reoxygenation, can lead to… »
Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in… »
DNA sequences in a gene's promoter region that mediate expression during hypoxia. Since unlike normal tissues, solid tumors frequently have regions… »
Ischemic brain damage in which the entire brain is deprived of oxygen. It may be fatal or lead to long term disabilities… »
The oil extracted from the leaves and flowering tops of Hyssopus officinalis. Hyssop oil is used in aromatherapy and for the treatment… »
Surgery to remove the uterus and, sometimes, the cervix. When the uterus and the cervix are removed, it is called a total… »
Historical term for a chronic, but fluctuating, disorder beginning in early life and characterized by recurrent and multiple somatic complaints not apparently… »
A procedure, also known as sonohysterography or saline infusion sonography, using a minimally invasive ultrasound technique to view the inside of the… »
A surgical incision made on the uterus to access the uterine cavity. »
A type of abortion where the product of conception is accessed through a surgical incision on the corpus uteri intended to terminate… »
A drug used to treat urinary problems caused by an enlarged prostate. It is also used to treat high blood pressure and… »
Medicamento que se usa para tratar los problemas urinarios a causa de una próstata agrandada. Asimismo, se usa para tratar la presión… »
A radioimmunoconjugate of a IgG2 monoclonal antibody (MoAb) 81C6 labeled with iodine 123 (I-123). MoAb 81C6 recognizes the extracellular matrix antigen tenascin… »
A radioimmunoconjugate of a rabbit antihuman ferritin IgG labeled with iodine 131 (I-131). Using anti-ferritin IgG as a carrier for I-131 may… »
A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 131 (I-131). MoAb A33 recognizes A33 antigen, a 43 KDa… »
A radioimmunoconjugate of the humanized monoclonal antibody CC49 labeled with iodine I 131. Iodine I 131 monoclonal antibody CC49 delivers beta and… »
A radioimmunoconjugate of a murine monoclonal antibody (MoAb) F19 labelled with Iodine 131 (I-131). MoAb F19 was raised against fibroblast activation protein… »
A radioimmunoconjugate of a murine monoclonal antibody, MoAb Lym-1, labeled with iodine 131 (I-131). MoAb Lym-1 recognizes an epitope of the histocompatibility… »
Interacting with p65 (RELA), widely expressed 36-38kDa unphosphorylated cytoplasmic ANK-repeat human I Kappa B Proteins A/B/E (NFKBI Family) inhibit NF-Kappa-B, trapping it… »
Encoded by glucocorticoid-inducible human NFKBIA Gene (NFKBI Family), 317-aa 36-kDa cytoplasmic I-Kappa-B-Alpha contains 5 ANK repeats that interact with p65 RELA C-terminal… »
A type of nuclear test of the thyroid that measures how much radioactive iodine is taken up by the thyroid gland in… »
An inherited lysosomal storage disease characterized by the presence of dense intracytoplasmic inclusions in mesenchymal cells, especially fibroblasts. Signs and symptoms include… »
An enzyme complex that is involved in serine/threonine phosphorylation, inflammation and the regulation of the nuclear factor kappa-light-chain-enhancer of activated B cells… »
Widely expressed by human NFKBIB Gene (NFKBI Family), 317-aa 36-kDa cytoplasmic I-Kappa-B-Beta contains 6 ANK repeats and interacts with the ligand-binding domain… »
Expressed in spleen, testis, lung, kidney, pancreas, heart, placenta, brain, granulocytes, and macrophages by human NFKBIE Gene (NFKBI), 361-aa 38-kDa cytoplasmic I-Kappa-B-Epsilon… »
A radioimmunoconjugate of a murine monoclonal antibody (MoAb) COL1, labeled with iodine 131 (I-131). COL1 recognizes an epitope of carcinoembryonic antigen (CEA),… »
The animal welfare assurance number issued by the NIH Office of Laboratory Animal Welfare (OLAW) after research protocols and evaluations are reviewed… »
Mammalian IAP Family Genes encode conserved Inhibitors of Apoptosis Proteins with an N-terminal domain containing 1-3 repeats of a 65-70-aa Cys- and… »
A family of proteins that are related structurally and functionally and are inhibitors of apoptosis. »
An orally bioavailable inhibitor of IAP (Inhibitor of Apoptosis Protein) family of proteins with potential apoptotic inducing and antineoplastic activity. IAP inhibitor… »
The hydrochloride salt of a small-molecule inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with potential antineoplastic activity. IAP inhibitor HGS1029… »
Human IAPP wild-type allele is located in the vicinity of 12p12.1 and is approximately 25 kb in length. This allele, which encodes… »
A state of ill health caused by medical treatment, usually due to mistakes made in treatment. »
A Kaposi sarcoma that develops after organ transplantation or immunosuppressive treatment. »
An iodinated analog of deoxycytidine used topically in the treatment of herpes labialis. »
A humanized monoclonal antibody against CD4, with anti-human immunodeficiency virus (HIV) activity. Ibalizumab binds to CD4, the primary receptor for HIV, thereby… »
A drug that is used to prevent and treat osteoporosis, and is being studied in the treatment of cancer that has spread… »
The sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in… »
Medicamento que se usa para prevenir y tratar la osteoporosis. Está en estudio para tratar el cáncer que se ha diseminado hasta… »
A third-generation amino-bisphosphonate with anti-resorptive and anti-hypercalcemic activities. Ibandronic acid binds to and adsorbs onto the surface of hydroxyapatite crystals in the… »
The Ibizan Hound is an agile, deer-like, athletic hound that has a long, arched neck, long wedge-shaped head, and very large, triangular… »
Inherited bone marrow failure syndrome. A rare disorder in which a person’s bone marrow is unable to make enough blood cells and… »
Trastorno poco frecuente por el que la médula ósea de una persona es incapaz de producir suficientes glóbulos sanguíneos y hay antecedentes… »
Sustancia que se usa para tratar ciertos trastornos del estómago y los intestinos, como la acidez y las úlceras. El IBP impide… »
A drug used to treat hormone-receptor positive (HR+), HER2 negative (HER2-) breast cancer that is advanced or has spread to other parts… »
A monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment and… »
Anticuerpo monoclonal radiomarcado que se usa para detectar ciertos tipos de linfoma no Hodgkin de células B y que está en estudio… »
A lipoprotein lipase (LPL) activator with antihyperlipidemic activity. Activation of LDL by ibrolipim lowers plasma triglycerides, with a concomitant elevation of high-density… »
A drug used to treat mantle cell lymphoma in patients who have already received other treatment. It is also being studied in… »
Medicamento que se usa para tratar el linfoma de células del manto en pacientes que ya recibieron otro tratamiento. También está en… »
A disorder of the intestines commonly marked by abdominal pain, bloating, and changes in a person’s bowel habits. This may include… »
A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It… »
Medicamento que se usa para tratar la fiebre, la hinchazón, el dolor y el enrojecimiento al impedir que el cuerpo elabore sustancias… »
The fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium… »
Modified T-lymphocytes expressing a 3rd generation chimeric antigen receptor (CAR) specific for the disialoganglioside GD2, which contains the CD3zeta chain, the signaling… »
This gene is involved in mediating integrin-binding interactions that result in cellular adhesion. »
Human ICAM1 wild-type allele is located within 19p13.3-p13.2 and is approximately 16 kb in length. This allele, which encodes intercellular adhesion molecule… »
This gene is involved in antigen-specific immune responses and NK-cell clearance. »
Human ICAM2 wild-type allele is located within 17q23-q25 and is approximately 4 kb in length. This allele, which encodes intercellular adhesion molecule… »
This gene is involved in the mediation of cellular adhesion, immune responses, and signal transduction. »
Human ICAM3 wild-type allele is located within 19p13.3-p13.2 and is approximately 6 kb in length. This allele, which encodes intercellular adhesion molecule… »
Afección por la que el corazón tiene dificultades para bombear la sangre a través del cuerpo. Puede formarse durante un… »
A small device used to correct a heartbeat that is abnormal (too fast, too slow, or irregular). The device is placed by… »
An abbreviation for a chemotherapy combination that is used to treat non-Hodgkin and Hodgkin lymphomas that have come back and do not… »
Abreviatura del nombre de una quimioterapia combinada que se usa para tratar el linfoma de Hodgkin y el linfoma no Hodgkin que… »
Continental material transport within a matrix of ice and deposited in marine sediments when the ice matrix melts. »
An abbreviation for a chemotherapy combination that is used to treat non-Hodgkin and Hodgkin lymphomas that have come back and do not… »
Edge of the ice sheet where melting and calving of icebergs occurs. »
Rapidly flowing ice generally in the bottom of an ice sheet and flowing from the middle to the ice sheet margin. … »
A country in northern Europe, island between the Greenland Sea and the North Atlantic Ocean, northwest of the UK. »
An Indo-European language belonging to the North Germanic (Scandinavian) branch; the official language of Iceland. »
ICH storage temperature, Q1A-Q1F. »
A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild… »
A non-hereditary form of ichthyosis characterized by plate-like scales on the legs, arms and occasionally the torso. »
A rare autosomal dominant inherited form of ichthyosis. It is characterized by the presence of an erythematous skin with blisters at… »
The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the… »
A drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the treatment of… »
Medicamento que se usa para tratar ciertos tipo de cáncer de seno (mama) en las mujeres posmenopáusicas. Asimismo, está en estudio para… »
An anticancer drug that stops tumor cells from growing by blocking the ability of cells to make DNA. It belongs to the… »
Medicamento contra el cáncer que impide que las células tumorales crezcan porque bloquea la capacidad de las células de producir ADN. Es… »
A drug used to treat chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia. It is used in patients who are… »
Medicamento que se usa para tratar la leucemia mielógena crónica (LMC) y la leucemia linfoblástica aguda positiva para el cromosoma Filadelfia. Se… »
An orally-available synthetic derivative of the beta-amino acid cispentacin with antifungal properties. Icofungipen blocks isoleucyl-tRNA synthetase and results in inhibition of protein… »
Human ICOS wild-type allele is located in the vicinity of 2q33 and is approximately 25 kb in length. This allele, which encodes… »
A polyunsaturated long-chain fatty acid with a 20-carbon backbone and 5 double bonds, originating from the 3rd, 6th, 9th, 12th and 15th… »
An orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several… »
Derived from Rockefeller Swiss mice that were disseminated to the Institute of Cancer Research in Philadelphia (1948). The ICR BR strain is… »
A fully human IgG1 monoclonal antibody directed against human vascular endothelial growth factor receptor 1 (VEGFR-1/FLT-1) with potential antiangiogenesis and antineoplastic… »
The determination of the amount of yellow color of a biological specimen, due to the presence of bile pigments. »
A specimen that exhibits a yellowish pigmentation due to jaundice. »
Afección en la cual la piel y el blanco de los ojos se tornan amarillentos, se oscurece la orina y el color… »
A test consisting of a lymphoma idiotype (Id)-specific protein conjugated to the immunogen keyhole limpet hemocyanin (KLH). As a test of… »
A test consisting of a myeloma idiotype (Id)-specific protein conjugated to the immunogen keyhole limpet hemocyanin (KLH). As a test of… »
A regimen consisting of ifosfamide and doxorubicin used for the treatment of high-risk childhood rhabdomyosarcoma. »
Human ID1 wild-type allele is located in the vicinity of 20q11 and is approximately 1 kb in length. This allele, which encodes… »
Human ID2 wild-type allele is located in the vicinity of 2p25 and is approximately 5 kb in length. This allele, which encodes… »
Human ID3 wild-type allele is located within 1p36.13-p36.12 and is approximately 2 kb in length. This allele, which encodes DNA-binding protein inhibitor… »
An induction regimen consisting of dexamethasone, cytarabine, thioguanine, etoposide and idarubicin administered on an intensively-timed schedule as a form of timed-sequential therapy… »
A regimen consisting of idarubicin, fludarabine, high-dose cytarabine and filgrastim (G-CSF), used as a remission-induction treatment for relapsed or refractory childhood acute… »
A drug used with other drugs to treat acute myelogenous leukemia (AML). It is also being studied in the treatment of other… »
Medicamento contra el cáncer que es un tipo de antibiótico antitumoral. También se llama 4-demetoxidaunorubicina. »
An anticancer drug that is a type of antitumor antibiotic. Also called 4-demethoxydaunorubicin. »
The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication… »
A sustained-release drug delivery embolization system containing small polymeric beads impregnated with the anthracycline antibiotic idarubicin with potential antineoplastic activity. The beads… »
Human IDE wild-type allele is located within 10q23-q25 and is approximately 122 kb in length. This allele, which encodes insulin-degrading enzyme protein,… »
The date and time span specifying the best time for an activity or event to begin and end. »
A drug used with the drug rituximab to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the… »
Medicamento que se usa con el rituximab para tratar ciertos tipos de linfoma no Hodgkin de células B. También está en… »
An orally bioavailable, small molecule inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinase (PI3K)… »
Exactly alike; incapable of being perceived as different; being the exact same one; coinciding exactly when superimposed; having properties with uniform values… »
Either of the two offspring resulting from a shared ovum. »
A class that has an unambiguous reference within the scope. It also has a potentially ambiguous name. »
The procedure of having an identity established. »
A set of terminology developed for use for the identification of medicinal products. »
Identified data and samples are labelled with personal identifiers such as name or identification numbers (e.g., social security or national insurance… »
One or more characters used to identify, name, or characterize the nature, properties, or contents of a thing. »
A character string as a unique identifier within the scope of the identifier root. »
The system that assigned the identifier. »
The variable that identifies a particular data element. »
The appraisal of the variable that identifies a particular data element. »
The set of characteristics by which a thing or person is recognized or known and that constitutes it's individuality or set… »
The IDH1 wt Allele is located in the vicinity of 2q33.3 and is approximately 19 kb in length. This allele, which encodes… »
An orally available inhibitor of isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity. Upon administration, AG-221 specifically inhibits IDH2 in the… »
Human IDH2 wt allele is located in the vicinity of 15q26.1 and is approximately 18 kb in length. This allele, which encodes… »
Describes a disease of unknown cause. »
Aplastic anemia without a known cause. »
A disease of the heart muscle or myocardium proper whose cause is unknown. »
A rare immunodeficiency syndrome characterized by the decrease of the CD4-positive lymphocytes below 300 per cubic millimeter in the absence of identifiable… »
A rare sleep disorder characterized by prolonged sleep at night and extreme sleepiness during the day. There are no apparent causes. This… »
A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as… »
A set of pneumonia-like symptoms (such as fever, chills, coughing, and breathing problems) that occur with no sign of infection in the… »
An electrocardiographic finding of ventricular tachycardia or ventricular fibrillation of unknown cause. »
A disease in which the alveoli (tiny air sacs at the end of the bronchioles in the lungs) are overgrown with fibrous… »
Increased blood pressure in the arteries of the lungs; the etiology is unknown. »
An electrocardiographic finding of blocked cardiac electrical impulse conduction along the fibers of the right bundle branch that cannot be attributed to… »
A condition in which platelets (blood cells that cause blood clots to form) are destroyed by the immune system. The low platelet… »
A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of the muscles of the legs, trunk, arms, and… »
Describe una enfermedad de origen desconocido. »
Unique, genetically controlled determinants present on antibodies whose specificity is limited to a single group of proteins (e.g., another antibody molecule or… »
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic… »
An electrocardiographic finding of three or more consecutive complexes of ventricular origin with a rate less than a certain threshold (100 or… »
An orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities. INCB024360 targets and binds to IDO1,… »
Medicamento que reduce el riesgo de que las células cancerosas crezcan porque interfiere con el ADN de las células. »
A drug that reduces the risk of cancer cell growth by interfering with the cells' DNA. »
A hydroxamic, non-amino acid derivative angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Idrapril competitively binds to and inhibits ACE, thereby blocking the… »
A synthetic flavonoid derivative. Idronoxil activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), and disrupts FLICE inhibitory protein (FLIP)… »
Human IDS wild-type allele is located in the vicinity of Xq28 and is approximately 27 kb in length. This allele, which encodes… »
Iduronate 2-sulfatase (550 aa, ~62 kDa) is encoded by the human IDS gene. This protein is involved in the degradation of… »
A regimen consisting of ifosfamide and doxorubicin used for the treatment of high-risk childhood rhabdomyosarcoma. »
An education plan for children with certain disabilities or health conditions, such as cancer. By law, these children must receive special… »
A mixture of oil and water that is combined with a specific antigen to boost the immune response to that antigen. … »
A drug that is used with other drugs to treat germ cell testicular cancer that did not respond to previous treatment with… »
Medicamento que se usa con otros medicamentos para tratar el que no respondió a tratamientos previos con otros fármacos. También… »
This gene is involved in the regulation of cell growth and proliferation. It also plays a role in immunity/defense. »
Human IFITM1 wild-type allele is located in the vicinity of 11p15.5 and is approximately 1 kb in length. This allele, which encodes… »
A regimen consisting of irinotecan, fluorouracil and leucovorin, all administered as bolus doses, and used for the treatment of advanced stage colorectal… »
A chemo-immunotherapy regimen consisting of irinotecan, fluorouracil, leucovorin and bevacizumab used for the treatment of advanced stage colorectal cancer. »
A regimen consisting of irinotecan, infusional fluorouracil and leucovorin used for the treatment of advanced stage colorectal cancer. This regimen differs from… »
A regimen consisting of irinotecan, infusional fluorouracil and leucovorin used for the treatment of advanced stage colorectal cancer. This regimen differs from… »
Medicamento que se usa para tratar el sarcoma de Kaposi relacionado con el sida en ciertos pacientes, la leucemia de células pilosas… »
Interferon alpha plays a role in viral infections. Signaling takes place through an IFN receptor complex consisting of two alpha chains (type… »
A drug used to treat AIDS-related Kaposi sarcoma in certain patients, hairy cell leukemia, and melanoma that has been removed by… »
IFN gamma receptor alpha chain (489 aa, 54 kD) is a cell communication process protein that is encoded by the human IFNGR1… »
The packaging of eukaryotic DNA into nucleosomes inhibits the access of factors to DNA and results in the repression of transcription, replication,… »
A chemoimmunotherapy regimen consisting of interferon and dacarbazine used for the treatment of advanced-stage or metastatic malignant melanoma. »
This gene plays a role in signal transduction and is involved in the immune response. »
Human IFNA13 wild-type allele is located in the vicinity of 9p22 and is approximately 1 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction, the immune response and positive regulation of apoptosis. »
Human IFNA2 wild-type allele is located in the vicinity of 9p22 and is approximately 1 kb in length. This allele, which encodes… »
This gene is involved in tyrosine-kinase signal transduction and receptor mediation. »
Human IFNAR1 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes… »
This gene is involved in tyrosine-kinase signal transduction that elicits signaling events in the Jak/Stat and IRS pathways. »
Human IFNAR2 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and immunoregulation. It is also involved in cell communication, migration, growth and proliferation. … »
Human IFNG wild-type allele is located in the vicinity of 12q14 and is approximately 5 kb in length. This allele, which encodes… »
This gene is involved in receptor-mediated signal transduction in the interferon gamma signaling pathway. »
Human IFNGR1 wild-type allele is located within 6q23-q24 and is approximately 22 kb in length. This allele, which encodes interferon-gamma receptor beta… »
This gene is involved in receptor-mediated signal transduction in the interferon gamma signaling pathway and mediates innate immune responses. »
Human IFNGR2 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes… »
This gene plays a role in both the antiviral response and signaling. »
Human IFNL1 wild-type allele is located in the vicinity of 19q13.13 and is approximately 2 kb in length. This allele, which encodes… »
This gene is involved in both immunomodulation and antiviral responses. »
Human IFNL2 wild-type allele is located in the vicinity of 19q13.13 and is approximately 2 kb in length. This allele, which encodes… »
This gene plays a role in cytokine signaling. »
Human IFNL3 wild-type allele is located in the vicinity of 19q13.13 and is approximately 1 kb in length. This allele, which encodes… »
This gene is involved in signal transduction, cell cycle control and the immune response. »
Human IFNW1 wild-type allele is located in the vicinity of 9p22 and is approximately 2 kb in length. This allele, which encodes… »
A test to check for blood in the stool. A brush is used to collect water drops from around the surface of… »
Prueba para verificar la presencia de sangre en las heces. Se usa un pincel para recolectar gotas de agua de la superficie… »
Medicamento que se usa con otros medicamentos para tratar el que no respondió a tratamientos previos con otros fármacos. También… »
A drug that is used with other drugs to treat germ cell testicular cancer that did not respond to previous treatment with… »
A regimen consisting of ifosfamide and vinorelbine used for the treatment of relapsed or refractory Hodgkin's lymphoma. »
A protein that is made by B cells and plasma cells (types of white blood cells) and helps the body fight… »
Proteína elaborada con células B y células plasmáticas (tipo de glóbulo blanco) que ayuda al cuerpo a combatir la infección. Algunas… »
Ig gamma-1 chain C region (330 aa, ~36 kDa) is encoded by the human IGHG1 gene. This protein is involved in the… »
Ig lambda-1 chain C regions (106 aa, ~11 kDa) is encoded by the human IGLC1 gene. This protein plays a role in… »
IgA is the immunoglobulin subclass that is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and… »
A chronic autoimmune glomerulonephritis characterized by the deposition of immunoglobulin A in the mesangium of the glomeruli. It is manifested with hematuria… »
This gene is involved in multiple signal transduction pathways. »
Human IGBP1 wild-type allele is located within Xq13.1-q13.3 and is approximately 33 kb in length. This allele, which encodes immunoglobulin-binding protein 1,… »
An immunoglobulin isotype (subclass). This isotype is expressed on naive B cells along with IgM. Little is known about its… »
An immunoglobulin isotype (subclass). This isotype has the unique ability to bind with high affinity to IgE receptors (FceRI) on mast… »
A protein made by the body that stimulates the growth of many types of cells. IGF is similar to insulin (a hormone… »
A humanized IgG1 insulin-like growth factor (IGF) monoclonal antibody targeting the IGF ligands 1 (IGF-1) and 2 (IGF-2), with potential antineoplastic… »
Insulin like growth factor 1 (IGF-1) and its receptor (IGF-1R) provide a potent proliferative signaling system that stimulates growth in many different… »
Autologous glioma cells treated ex vivo with an 18-mer antisense oligodeoxynucleotide of insulin-like growth factor receptor 1 (IGF-1R/AS ODN), with potential antineoplastic… »
A substance being studied in the treatment of cancer. It blocks a protein called IGF-1R, which is found at high levels in… »
An orally bioavailable inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. IGF-1R inhibitor PL225B selectively binds to… »
An orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR… »
Encoded by human KOC1 Gene, IGF-II mRNA-Binding Protein 3 contains a KH domain and binds to the 5-prime UTR of the IGF-II… »
This gene is involved in cellular communication, growth and proliferation. It also plays a role in the regulation of muscular and skeletal… »
Human IGF1 wild-type allele is located within 12q22-q23 and is approximately 85 kb in length. This allele, which encodes insulin-like growth factor… »
IGF-1R, the type 1 receptor for insulin-like growth factor, mediates cell survival and growth in response to its ligands IGF-1 and… »
This gene is involved in the regulation of apoptosis and cell proliferation and plays a role in cellular transformation and malignancy. … »
An immunohistochemical diagnostic test utilizing an antibody to detect IGF1R in tissues. »
Human IGF1R wild-type allele is located in the vicinity of 15q26.3 and is approximately 309 kb in length. This allele, which encodes… »
This gene plays a role in cell growth and proliferation. It is also involved in the regulation of prenatal skeletal and muscular… »
Human IGF2 wild-type allele is located in the vicinity of 11p15.5 and is approximately 15 kb in length. This allele, which encodes… »
This gene plays a role in RNA binding interactions, which effects insulin regulation. »
Human IGF2BP3 wild-type allele is located within 7p11 and is approximately 160 kb in length. This allele, which encodes putative RNA binding… »
This gene is involved in intracellular trafficking and receptor signaling. »
Human IGF2R wild-type allele is located within 6q26 and is approximately 137 kb in length. This allele, which encodes cation-independent mannose-6-phosphate receptor… »
This gene plays a role in insulin-like growth factor modulation and degradation. »
Human IGFBP1 wild-type allele is located within 7p13-p12 and is approximately 5 kb in length. This allele, which encodes insulin-like growth factor-binding… »
This gene plays a role in insulin-like growth factor modulation and intercellular communication. »
Human IGFBP2 wild-type allele is located within 2q33-q34 and is approximately 31 kb in length. This allele, which encodes insulin-like growth factor-binding… »
This gene plays an inhibitory role in the regulation of extravascular tissue growth. »
Human IGFBP3 wild-type allele is located within 7p13-p12 and is approximately 9 kb in length. This allele, which encodes insulin-like growth factor-binding… »
This gene plays a role in insulin-like growth factor modulation and cellular growth inhibition. »
Human IGFBP4 wild-type allele is located within 17q12-q21.1 and is approximately 14 kb in length. This allele, which encodes insulin-like growth factor-binding… »
This gene plays a role in the intracellular transport of insulin-like growth factor moieties. »
Human IGFBP5 wild-type allele is located within 2q33-q36 and is approximately 23 kb in length. This allele, which encodes insulin-like growth factor-binding… »
This gene plays an inhibitory role in the regulation of cellular growth. »
Human IGFBP6 wild-type allele is located within 12q13 and is approximately 5 kb in length. This allele, which encodes insulin-like growth factor-binding… »
This gene may play a role in growth factor signal modulation and tumor suppression. »
Human IGFBP7 wild-type allele is located in the vicinity of 4q12 and is approximately 79 kb in length. This allele, which encodes… »
A protein found on the surface of some types of cells that binds to insulin-like growth factor (IGF). This causes the cells… »
An immunoglobulin isotype (subclass) that characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a,… »
Expressed in monocytes, macrophages, neutrophils, eosinophils, platelets, NK cells, and T- and B-lymphocytes by human FCGR2A Gene, 281-aa (mature) IgG Fc Receptor… »
Expressed as 3 alternative isoforms in monocytes, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B cells, platelets, and placental endothelial by human FCGR2B… »
Expressed as 4 alternative isoforms in monocytes, macrophages, polymorphonuclear cells, and natural killer cells (Isoform 1) by human FCGR2C Gene, IgG Fc… »
Expressed on natural killer cells, macrophages, T cells, immature thymocytes, and trophoblasts by human FCGR3A Gene, 254-aa 29-kDa (precursor) glycosylated IgG Fc… »
Expressed (as NA-1, NA-2, and SH allelic forms) specifically by neutrophils and stimulated eosinophils, human FCGR3B Gene encodes 233-aa 26-kDa (precursor) monomeric… »
The determination of the total amount of IgG, IgM, and IgA present in a sample. »
A unit for semiquantitative measurement of IgG autoantibodies to proteins associated with negatively charged phospholipids evaluated in ELISA serum anticardiolipin or anionic… »
An immunotoxin of monoclonal antibody (MoAb) RFB4 covalently linked to a single deglycosylated ricin toxin A-chain (dgA), originated from castor beans. MoAb… »
A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of melanoma that has spread to distant… »
Anticuerpo monoclonal ligado a una sustancia tóxica. Está en estudio para el tratamiento del melanoma que se ha diseminado hasta partes distantes… »
A subtype of IgG that makes up a minor part of circulating antibodies in healthy individuals. It is elevated in various diseases… »
A recently described mass-forming lesion that occurs in the pancreas, submandibular glands, lacrimal glands, lymph nodes, and hepatobiliary tract. It is… »
This gene is involved in immunoglobulin heavy chain structure. »
Human IGHG1 wild-type allele is located in the vicinity of 14q32.33 and is approximately 7 kb in length. This allele, which encodes… »
This gene plays a role in immunoglobulin light chain structure. »
Human IGLC1 wild-type allele is located in the vicinity of 22q11.22 and is approximately 0.5 kb in length. This allele, which encodes… »
The major immunoglobulin secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because… »
A unit for semiquantitative measurement of IgM autoantibodies to proteins associated with negatively charged phospholipids evaluated in ELISA serum anticardiolipin or anionic… »
A device designed to light a fire. »
A procedure that uses a computer to create a picture of a tumor to help guide the radiation beam during radiation… »
This gene is involved in cellular proliferation and motility. »
Human IGSF8 wild-type allele is located in the vicinity of 1q23.1 and is approximately 7 kb in length. This allele, which encodes… »
A substance being studied for its ability to prevent damage to normal tissue caused by radiation therapy. It is a type of… »
An oligomeric proanthocyanidin extracted from grape seeds. IH636 grape seed proanthocyanidin extract exhibits dose-dependent free-radical scavenging and antioxidant properties. »
Human IHH wild-type allele is located within 2q33-q35 and is approximately 6 kb in length. This allele, which encodes indian hedgehog protein,… »
International Index of Erectile Function (IIEF) Over the past four weeks how often were you able to get an erection during sexual… »
International Index of Erectile Function (IIEF) Over the past four weeks during sexual intercourse, how often were you able to maintain your… »
International Index of Erectile Function (IIEF) Over the past four weeks when you attempted sexual intercourse, how often were you able to… »
International Index of Erectile Function (IIEF) Over the past four weeks when you had sexual stimulation or intercourse, how often did you… »
International Index of Erectile Function (IIEF) Over the past four weeks when you had erections with sexual stimulation, how often were your… »
International Index of Erectile Function (IIEF) Over the past four weeks how many times have you attempted sexual intercourse? »
International Index of Erectile Function (IIEF) Over the past four weeks how much have you enjoyed sexual intercourse? »
International Index of Erectile Function (IIEF) Over the past four weeks when you had sexual stimulation or intercourse, how often did you… »
International Index of Erectile Function (IIEF) Over the past four weeks how often have you felt sexual desire? »
International Index of Erectile Function (IIEF) Over the past four weeks when you attempted sexual intercourse, how often was it satisfactory for… »
International Index of Erectile Function (IIEF) Over the past four weeks during sexual intercourse, how difficult was it to maintain your erection… »
International Index of Erectile Function (IIEF) Over the past four weeks how would you rate your level of sexual desire? »
International Index of Erectile Function (IIEF) Over the past four weeks how satisfied have you been with your overall sex life? … »
International Index of Erectile Function (IIEF) Over the past four weeks how satisfied have you been with your sexual relationship with your… »
International Index of Erectile Function (IIEF) Over the past four weeks how do you rate your confidence that you could get and… »
A question associated with the IIEF questionnaire. »
This gene plays a role in the positive regulation of apoptosis. »
Human IKBIP wild-type allele is located in the vicinity of 12q23.1 and is approximately 31 kb in length. This allele, which encodes… »
This gene is involved in protein phosphorylation. »
Human IKBKB wild-type allele is located in the vicinity of 8p11.2 and is approximately 61 kb in length. This allele, which encodes… »
This gene plays a role in the regulation of signal transduction. »
Human IKBKG wild-type allele is located in the vicinity of Xq28 and is approximately 25 kb in length. This allele, which encodes… »
This gene is involved in B-cell and T-cell maturation. »
Human IKZF1 wild-type allele is located within 7p13-p11.1 and is approximately 123 kb in length. This allele, which encodes DNA-binding protein Ikaros,… »
A fusion gene that results from a chromosomal translocation t(3;7)(q27;p12) which fuses the promoter of the IKZF1 gene near the 5' end… »
This gene is involved in both transcription and lymphocyte development. »
Human IKZF2 wild-type allele is located in the vicinity of 2q34 and is approximately 152 kb in length. This allele, which encodes… »