Medical Topics
The learned profession that is mastered by graduate study in a law school and that is responsible for the judicial system. … »
Synthetic compounds or mixtures administered orally or rectally with laxative activity. A laxative preparation is used to promote bowel movement to treat… »
A drug being studied in the treatment of cancer. It blocks enzymes needed for cells to grow and divide and may kill… »
Human LBP wild-type allele is located in the vicinity of 20q11.23 and is approximately 31 kb in length. This allele, which encodes… »
A group of rare disorders in which too many Langerhans cells (a type of white blood cell) grow in certain tissues and… »
A condition in which abnormal cells are found in the lobules of the breast. This condition seldom becomes invasive cancer. However, having… »
Human LCK wild-type allele is located in the vicinity of 1p34.3 and is approximately 35 kb in length. This allele, which encodes… »
This gene plays a role in phospholipid metabolism. »
Human LCLAT1 wild-type allele is located in the vicinity of 2p23.1 and is approximately 197 kb in length. This allele, which encodes… »
This gene may play a role in both the transport of hydrophobic molecules and the mediation of inflammation. »
Human LCN2 wild-type allele is located in the vicinity of 9q34 and is approximately 5 kb in length. This allele, which encodes… »
Human LCP1 wild-type allele is located in the vicinity of 13q14.3 and is approximately 56 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(3;13)(q27;q14) which fuses the promoter region of the LCP1 gene near the 5'… »
This gene is involved in signal transduction. It plays a role in the activation and development of T cells. »
Human LCP2 wild-type allele is located within 5q33.1-qter and is approximately 50 kb in length. This allele, which encodes lymphocyte cytosolic protein… »
The dose of a chemical or biologic preparation (e.g., a bacterial exotoxin or a suspension of bacteria) that is likely to cause… »
Human LDB1 wild-type allele is located within 10q24-q25 and is approximately 13 kb in length. This allele, which encodes LIM domain-binding protein… »
Human LDB2 wild-type allele is located in the vicinity of 4p16 and is approximately 397 kb in length. This allele, which encodes… »
A drug used to treat locally advanced basal cell carcinoma (BCC) that has come back after surgery or radiation therapy. It is… »
One of a group of enzymes found in the blood and other body tissues, and involved in energy production in cells. An… »
The determination of the ratio of LDH isoenzyme 1 compared to total LDH present in a sample. The measurement may be expressed… »
The determination of the ratio of LDH isoenzyme 2 compared to total LDH present in a sample. The measurement may be expressed… »
The determination of the ratio of LDH isoenzyme 3 compared to total LDH present in a sample. The measurement may be expressed… »
The determination of the ratio of LDH isoenzyme 4 compared to total LDH present in a sample. The measurement may be expressed… »
The determination of the ratio of LDH isoenzyme 5 compared to total LDH present in a sample. The measurement may be expressed… »
Human LDHA wild-type allele is located in the vicinity of 11p15.4 and is approximately 14 kb in length. This allele, which encodes… »
The determination of the amount of the average particle size of low-density lipoprotein in a sample. »
Low-density lipoprotein (LDL) is a plasma lipoprotein particle whose lipid component includes cholesterol and triglycerides and is commonly referred to as bad… »
LDLR chaperone MESD (234 aa, ~26 kDa) is encoded by the human MESDC2 gene. This protein is involved in the folding of… »
This gene plays a role in the modulation of ligand-specific receptor-mediated endocytosis, and also plays a regulatory role in cholesterol synthesis. … »
Human LDLR wild-type allele is located in the vicinity of 19p13.3 and is approximately 44 kb in length. This allele, which encodes… »
Derived by Long and Evans (1915) by crossing female Wistar rats with a wild gray male, the Long-Evans rat was disseminated to… »
A yellow, orange or red colored, crystalline, inorganic compound that emits toxic chromium fumes upon heating. Lead chromate is highly corrosive and… »
A microscopy staining method that utilizes lead citrate, a mixture of lead nitrate and sodium citrate, and has applications for electron microscopy… »
In medicine, a chemical compound that shows promise as a treatment for a disease and may lead to the development of a… »
A bundle of leads designed to connect between a pacing device and implanted heart electrodes. »
An insulated electrical conductor designed to connect to an electrical device. »
Movement of a lead away from the original implantation site. »
The primary individual who over a period of time checks on and maintains continuous observation of state, condition, situation, or process relating… »
The removal of one or more lead wires from the heart in a patient with pacemaker or implantable defibrillator. »
Specifies the principal entity responsible for the study. »
An element with atomic symbol Pb, atomic number 82, and atomic weight 207.2. »
The principal administrative organization responsible for the research conducted. »
A radioimmunoconjugate containing the recombinant humanized monoclonal antibody trastuzumab conjugated with the bifunctional chelating agent TCMC ((1,4,7,10-Tetra-(2-Carbamoyl Methyl)-Cyclododecane), and radiolabeled with the… »
The spatial property of the way in which an electrocardiogram lead is placed on the body. »
Limb leads on the back (shoulder and on the hips). »
An electrocardiogram (ECG) lead placement whereby the X+ lead is placed at the right mid-axillary line at the 4th intercostal space, X-… »
An electrocardiogram (ECG) lead placement that is a type of uncorrected vectorcardiograph. This lead system is based on a rectangular body… »
An electrocardiogram (ECG) lead placement whereby 4 chest electrodes and 1 reference electrode are used to allow for continuous monitoring at the… »
An electrocardiogram (ECG) lead placement for determining 3 orthogonal components X (right to left direction), Y (foot to head direction) and Z… »
An electrocardiogram (ECG) lead placement for determining 3 orthogonal components X (back to front), Y (right to left) and Z (foot to… »
An electrocardiogram (ECG) lead placement that allows monitoring and recording of cardiac electrical activity. A V1-type lead is used whose positive electrode… »
An electrocardiographic lead placement schema in which the "V" leads are placed one intercostal space cephalad to the position they would have… »
Lead is a metal that occurs naturally in the earth's crust. Lead can be found in all parts of our… »
An indicator that can be set or unset in order to signal whether a particular agent is a primary medical product, practice,… »
An augmented unipolar lead placed at the sixth intercostal space on the midaxillary line. »
A bipolar EKG lead with the right thoracic limb electrode placed on the manubrium and left thoracic limb electrode placed at the… »
A unipolar chest lead used mostly in large animals. Placed on the sixth ICS on the right side of the thorax along… »
V1 electrode (+) placed in the 6th intercostal space on the left side of the thorax along a line parallel to the… »
V2 electrode (+) placed in the 6th intercostal space on the left side of the thorax along a line parallel to the… »
A bipolar electrocardiogram limb lead which records the voltage between the negative electrode on the right thoracic limb and the positive electrode… »
A bipolar electrocardiogram limb lead which records the voltage between the negative electrode on the right thoracic limb and the positive electrode… »
A bipolar electrocardiogram limb lead which records the voltage between the negative electrode on the left thoracic limb and the positive electrode… »
A unipolar precordial lead placed at the second intercostal space to the left of the sternum. »
A unipolar electrocardiogram lead site; the electrode is placed at the fourth intercostal space on the anterior chest wall (between ribs 4… »
A unipolar chest lead at which the electrode is placed over the dorsal spinous process of 7th thoracic vertebra. »
A unipolar electrocardiogram lead site; the electrode is placed on the anterior chest wall at the fourth intercostal space (between ribs 4… »
A unipolar electrocardiogram lead site; the electrode is placed on the anterior chest wall midway between leads V2 and V4. In large… »
A unipolar electrocardiogram lead site; the electrode is placed at the fifth intercostal space on the anterior chest wall (between ribs 5… »
A unipolar electrocardiogram lead site; the electrode is placed on the anterior chest wall level with lead V4 at the left anterior… »
A unipolar electrocardiogram lead site at which the electrode is placed on the anterior chest wall level with lead V5 at the… »
A primary medical product, practice, or application that is tested in a multi-agent clinical study. »
A device designed to form the end of an electrical lead. »
A special organ of plant in the form of lateral outgrowth from the stem. Leaves usually consist of a blade, or lamina,… »
A structure composed of a short stem with embryonic leaves, with bud primordial in the axils and at the apex. »
Any device that resembles a small leaf, especially one that has two thin blades hinged in the center. »
A disk-shaped valve component of a tilting disk mechanical heart valve. »
Issue associated with the escape of a liquid or gas from the vessel or container in which it is housed. »
The discharge of amniotic fluid vaginally due to a tear or rupture in the amniotic membrane. »
The mass of the body minus the fat. »
A group of disorders that affect a person's ability to learn or process specific types of information which is in contrast to… »
Learning disorders affect how a person understands, remembers and responds to new information. People with learning disorders may have problems »
A popular criterion used for a cost function, namely minimizing the sum of the squares of the differences between the data points… »
A hereditary disorder caused by mitochondrial mutations, resulting in the degeneration of the retinal ganglion cells and optic atrophy. It is characterized… »
A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and inhibits IL-13-mediated pathways. IL-13,… »
Carries a mutation causing fulminated hepatitis and jaundice at about four months of age. Clinical symptoms include severe jaundice, bleeding, oliguria, loss… »
A disorder of lipoprotein metabolism caused by mutations in the LCAT gene. It is characterized by deficiency of the enzyme lecithin cholesterol… »
A genus of facultatively anaerobic, Gram negative, rod shaped bacterium in the phylum Fusobacteria and the family Enterobacteriaceae . »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is motile, lactose and beta glucuronidase… »
A complex molecule that has both protein and sugars. Lectins are able to bind to the outside of a cell and cause… »
The complement cascade of proteolytic factors involved in cellular lysis can be initiated by several different factors, including antibody-dependent and antibody-independent recognition… »
An agent that inhibits metastasis by interfering with the interaction between tumor cells and lectins. »
Treatment with drugs that become active and may kill cancer cells when exposed to light. LED therapy is a type of photodynamic… »
A technique that uses electric current passed through a thin wire loop to remove abnormal tissue. Also called loop electrosurgical excision procedure… »
Human LEF1 wild-type allele is located within 4q23-q25 and is approximately 121 kb in length. This allele, which encodes lymphoid enhancer-binding factor… »
An anticancer drug that works by inhibiting a cancer cell growth factor. Also called SU101. »
The adrenal gland located on the left side of the body. »
A designation that a patient has chosen not to heed the directions that medical staff has advised, and has chosen to leave… »
The arteries that arise from the left anterior descending (LAD) artery that supply the interventricular septum. »
An electrocardiographic finding of a slightly widened QRS duration (typically less than 120 ms) with leftward frontal plane QRS axis and typically… »
Couinaud segment III, corresponding to the lateral segment of the left lobe of the liver, located to the left of the inferior… »
The portion of the upper extremity between the shoulder and the wrist and located on the left side of the body. … »
A cardiac myxoma arising from the left atrium. »
The diameter across the left atrium measured at the end of systole. »
A descriptive adjective assigned to the quantitative measurement of the left cardiac atrium. »
A measurement obtained from radiographic image of the left cardiac atrium. »
A vein in the upper chest on the left side of the body that joins with the right innominate vein to form… »
The hemispheric projection, including the mammary gland, located on the anterior portion of the chest, lateral to the midline, on the side… »
An imaging artifact resulting from a patient left bundle branch block. »
An electrocardiographic finding of a wide QRS complex with evidence of delayed conduction to the left ventricle, manifested as a widened initial… »
The posterior descending artery (PDA) and posterolateral artery (PLA) arises from the left circumflex artery. »
A procedure involving a mechanical pump which receives blood from the left ventricle and delivers it to the aorta. »
The cardiac rhythm device malfunction affected the left ventricular (LV) pacing. »
The degree of impairment of the left cardiac ventricle to contract efficiently. »
An examination and assessment of the inability of the left ventricle to effectively pump blood to the body. »
The left half of the cerebrum that controls the muscles on the right side of the body. »
Surgical removal of the left part of the colon. »
The portion of the large intestine that includes the descending and sigmoid colon. »
An artery arising from the aortic arch that supplies the head and neck. »
The common iliac artery situated on the left side of the body. »
A coronary artery that arises from the aorta and bifurcates into the left anterior descending artery and the left circumflex artery. … »
Any artery arising from the left coronary artery. »
The muscle that creates the rounded contour of the shoulder which originates from the lateral third of the clavicle, the superior surface… »
The fallopian tube that extends from the uterus to the ovary in the left side of the pelvic cavity. »
One of the three gluteal muscles on the lateral surface of the pelvic bone that abducts and rotates the thigh located on… »
The passage of a catheter into the left ventricle for the purposes of angiography, measurement of ventricular pressures, and/or oxygen saturation. … »
Surgical removal of the left hemisphere of the liver. »
The duct that drains bile from the left lobe of the liver into the common hepatic duct. »
The area under the left costal margin of the ribs. »
A gyrus on the outer surface of the left frontal lobe of the cerebrum located between the inferior frontal sulcus and the… »
Couinaud segment IVb, corresponding to the medial segment of the left lobe of the liver, located inferiorly. »
The lower left zone of the abdomen containing parts of the small intestine, descending and sigmoid colon, and the left ovary and… »
A bean-shaped retroperitoneal organ situated below the diaphragm and posterior to the spleen. »
Lying down or reclining with the left side in a downward direction. »
The smaller lobe of the liver extending into the left side of the body. »
The distal half of the left upper limb between the elbow and the wrist. »
The central left zone of the abdomen containing parts of the small intestine, descending colon, and the left kidney. »
An alveolus located in the left lung. »
A bronchiole located in the left lung. »
A respiratory bronchiole located in the left lung. »
A terminal bronchiole located in the left lung. »
One of the two main bronchi. It is narrower but longer than the right main bronchus and connects to the left… »
Percent luminal narrowing of the left main coronary artery, at the point of maximal stenosis of the left main coronary artery. … »
The percentage of narrowing of the left main coronary artery. »
A fetal position during delivery in which the head of the fetus is in the birth canal facing the area between the… »
Surgery to remove the left ovary. »
The ovary that is located in the left side of the pelvis. »
The portion of the diaphragm in the left side of the body. »
An electrocardiographic finding of an S1Q3 pattern and QRS axis greater than or equal to 120 degrees. It is usually seen in… »
In an individual with a left-dominant heart, this branch arises from the circumflex artery atrioventricular groove continuation and supplies the inferior apex… »
Couinaud segment II, corresponding to the lateral segment of the left lobe of the liver, located to the left of the superior… »
A blood vessel arising from the bifurcation of the pulmonary artery that carries deoxygenated blood to the left lung. »
A vein that returns oxygenated blood from the left lung to the left atrium of the heart. »
Surgery performed to reduce the size of the left breast. »
An artery arising from the abdominal aorta that supplies the left kidney. »
A vein that drains blood from the left kidney into the inferior vena cava. »
Surgery to remove part or all of the left fallopian tube. »
Surgical removal of the left fallopian tube and left ovary. »
An artery arising from the abdominal aorta, below the renal artery, that supplies the left testicle. »
A vein that forms the spermatic plexus to drain the left testis into the left renal vein. »
An artery arising from the aortic arch that supplies the left arm. »
A vein that extends along the bottom of the twelfth rib on the left side of the body. »
Couinaud segment IVa, corresponding to the medial segment of the left lobe of the liver, located superiorly. »
A vein that drains blood from the left adrenal gland into the left renal artery. »
The testis on the left side of the body. »
A part of the lower limb, located between the hip and the knee and located on the left side of the… »
The cone-like lobe of the thyroid gland that is located in the left side of the trachea. »
The ureter connecting the left kidney to the bladder. »
The largest muscle in the quadriceps femoris that is responsible for extending and stabilizing the knee located on the left side of… »
The left lower chamber of the heart that receives blood from the left atrium and pumps it through the aorta to the… »
The diameter across the ventricle at the end of diastole, excluding the thickness of the walls. »
A measurement obtained from a radiographic image of the left ventricle during the final moment of ventricular relaxation, when the ventricle fills… »
A measurement obtained from a radiographic image of the left ventricle during the final moment of ventricular contraction, when the ventricle empties… »
A descriptive characterization of the size of the left cardiac ventricle. »
A bulge or ballooning in the wall of the left ventricle of the heart. »
A mechanical pump which also includes a control system and an energy supply. It receives blood from the left ventricle and delivers… »
An electrocardiographic finding in which there is evidence that electrical transmission through the left ventricle is impaired. »
The diameter across the ventricle at the end of systole, excluding the thickness of the walls. »
Impairment of the left ventricle to either fill or eject adequately. »
The fraction of the left ventricular end diastolic volume ejected with each beat. The left ventricular ejection fraction is equal to the… »
The time it take to eject blood from the left ventricle. Measurement begins when the aortic valve opens and ends when the… »
The outermost layer of cardiac tissue lining of the left ventricle. »
Failure of adequate output by the left ventricle despite an increase in distending pressure and in end-diastolic volume, with dyspnea, orthopnea, and… »
Enlargement or overgrowth of the myocardium of the left ventricle, due to chronic pressure overload. »
An electrocardiographic finding suggestive of a hypertrophied left ventricle, characterized by large QRS amplitudes and secondary findings of left atrial enlargement, left… »
An electrocardiographic finding suggestive of a hypertrophied left ventricle, characterized by large QRS amplitudes, ST depression and T wave inversion. »
The left ventricular volume calculated as the difference between the epicardium delimited volume and the left ventricular chamber volume. »
An uncommon congenital abnormality where the left ventricular myocardium fails to compact during embryonic development, leading to cardiomyopathy with a variable degree… »
Obstruction of the left ventricular outflow tract. It is caused by aortic valve, supravalvar, or subvalvar defects. »
The degree of impairment of the left cardiac ventricle to contract efficiently. »
Defined in terms of ejection fraction, a good clinical indicator of ventricular systolic function. Normal ejection fraction is 0.50 or more… »
Containing a TGF-beta family domain, similar to LEFTYA, and encoded by human LEFTB Gene (TGF-Beta Family), secreted 366-amino acid 41-kD Left-Right Determination… »
This gene is involved in left-right asymmetry determination of organ systems during development. »
Human LEFTY1 wild-type allele is located in the vicinity of 1q42.1 and is approximately 3 kb in length. This allele, which encodes… »
This gene is involved in embryogenesis and morphogenesis. It plays a role in the determination of left-right asymmetry. »
Human LEFTY2 wild-type allele is located in the vicinity of 1q42.1 and is approximately 5 kb in length. This allele, which encodes… »
Your legs are made up of bones, blood vessels, muscles, and other connective tissue. They are important for motion and standing. Playing… »
General or unspecified injuries involving the leg. »
A person of legal age to consent to a procedure as specifed by local regulation. »
A group or agency that gives legal help to people with low incomes. Health legal aid workers help people with issues related… »
A class of professional or vocational positions of employment that involve legal activities. »
Family members related by secondary marriage or other legal arrangement. »
An individual with expertise in the law who provides legal counsel and representation to the individual, company, institution, or organization taking responsibility… »
Termination of pregnancy under conditions allowed under local laws. (POPLINE Thesaurus, 1991) »
Animal drugs that are marketed without going through the standard drug approval process. These drugs are often intended for use in species… »
A small, commonly white-colored breed of poultry that is renowned for its ability to produce up to 300 chalk white eggs per… »
A genus of Gram-negative aerobic, motile, nonacid fast, nonencapsulated, gram-negative bacilli that have a nonfermentative metabolism in the phylum Proteobacteria. »
A species of aerobic, gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is motile, nonacid fast, nonencapsulated, nonfermentative and… »
A species of aerobic, gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is motile by flagella, nonacid fast, pleomorphic,… »
The determination of the amount of Legionella pneumophila antigen present in a sample. »
The determination of the amount of Legionella pneumophila IgG antibody present in a sample. »
The determination of the amount of Legionella pneumophila IgG and IgM antibody present in a sample. »
The determination of the amount of Legionella pneumophila IgM antibody present in a sample. »
Legionnaires' disease is a type of pneumonia caused by bacteria. You usually get it by breathing in mist from water that contains… »
A go-between in the legislature »
A question about whether an individual's legs or feet are or were swollen. »
A genus of Gram positive, coryneform bacterium assigned to the phylum Actinobacteria and the family Microbacteriaceae. »
A species of aerobic, Gram positive, rod shaped, coryneform bacteria assigned to the phylum Actinobacteria. This species is motile by long peritrichous… »
An inherited disorder affecting the nervous system, caused by genetic mutations in the mitochondrial DNA or deficiency of pyruvate dehydrogenase. Signs and… »
A benign smooth muscle tumor, usually in the uterus or gastrointestinal tract. Also called fibroid. »
A benign smooth muscle neoplasm arising from the central nervous system. It is characterized by the presence of intersecting fascicles composed… »
Circumscribed expansile neoplasm of spindle cells arranged in palisading pattern. Neoplasms are positive for myosin. »
A condition characterized by the presence of numerous small benign smooth muscle neoplasms located throughout the body. »
A malignant (cancer) tumor of smooth muscle cells that can arise almost anywhere in the body, but is most common in the… »
A clinical finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7… »
A finding about one or more characteristics of leiomyosarcoma and endometrial stromal sarcoma, following the rules of the TNM AJCC v7 classification… »
An aggressive malignant smooth muscle neoplasm, arising from the central nervous system. It is characterized by a proliferation of neoplastic spindle… »
Invasive neoplasm of spindle cells arranged in palisading pattern. Neoplasms are positive for myosin. »
Malignant neoplasm generally composed of spindle cells that exhibit smooth muscle differentiation. »
An aggressive malignant smooth muscle neoplasm, arising from the walls of the vascular system. It is characterized by a proliferation of… »
A parasitic infection caused by protozoa of the genus Leishmania. It is transmitted to humans via the bite of sandflies. There are… »
Leishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by… »
Activities done for the purpose of relaxation or diversion from routine work. »
Time used for ease and relaxation. »
Galactose is a hexose sugar found in the disaccharide lactose. Galactose has six carbons like glucose and differs from glucose only… »
A genus of facultatively anaerobic, Gram negative, rod shaped bacterium in the phylum Proteobacteria and the family Enterobacteriaceae. »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is nonmotile, hydrogen sulfide, tyrosine and… »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is hydrogen sulfide positive, citrate and… »
A small, yellow citrus fruit that is a source of citric acid and ascorbic acid (vitamin C). The juice is used to… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
The oil extracted from the fruit peel of Citrus limon. Lemon oil is used as a flavoring and for its aromatic… »
A drug that is similar to thalidomide, and is used to treat multiple myeloma and certain types of anemia. It is also… »
A regimen consisting of lenalidomide and dexamethasone used to treat relapsed or refractory multiple myeloma. »
The linear extent in space from one end of something to the other end, or the extent of something from beginning to… »
The duration of time from initial contact with a substance until the appearance of undesired symptoms. »
A syndrome characterized by frequent episodes of epilepsy during childhood. The epileptic episodes may be tonic, atonic, myoclonic, or absence seizures. It… »
A glycosylated form of a recombinant therapeutic agent which is chemically identical to or similar to an endogenous human granulocyte colony-stimulating factor… »
A clear disk that focuses light, as in a camera or microscope. In the eye, the lens is a clear, curved structure… »
A transparent, elastic membrane that encloses the lens of the eye. »
An electric or optical device designed to focus electromagnetic radiation. »
The transparent, elongated cells extending from the posterior to anterior pole of the eye forming the concentric layers of the crystalline… »
Incomplete rupture of the zonule with the displaced lens remaining behind the pupil. In dislocation, or complete rupture, the lens is displaced… »
Autologous CD34+ hematopoietic stem cells transduced with Lenti-D lentiviral vector encoding the human ATP-binding cassette, sub-family D, member 1 (ABCD1) cDNA, for… »
A large, cone-shaped area of gray matter within the basal ganglia comprised of the globus pallidus and putamen that is surrounded primarily… »
A flat, benign, pigmented spot on the skin caused by excessive deposition of melanin from an increased number of melanocytes in the… »
An atypical proliferation of atypical melanocytes in the dermal-epidermal junction, without infiltration of the papillary or reticular dermis. The melanocytic proliferation is… »
A melanoma of the skin characterized by single cell infiltration of the papillary dermis by atypical melanocytes, in a background of lentigo… »
The most common form of the skin disorder lentigo, characterized by a single or multiple benign, pigmented macules of unknown etiology that… »
A beta-glucan (a type of polysaccharide) from the mushroom Lentinus edodes (shiitake mushroom). It has been studied in Japan as a treatment… »
A genus of the family Retroviridae consisting of non-oncogenic retroviruses that produce multi-organ diseases characterized by long incubation periods and persistent… »
Autologous, CD34-positive hematopoietic progenitor cells (HPCs) transduced with rHIV7-shI-TAR-CCR5RZ, a lentiviral vector encoding three anti-human immunodeficiency virus (HIV) RNA genes, with potential… »
A synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic… »
A drug used with everolimus to treat advanced renal cell carcinoma (a type of kidney cancer) that was treated with antiangiogenesis therapy… »
A genetic syndrome caused by mutations in the PTPN11 and RAF1 genes. It is characterized by the following abnormalities: multiple lentigines, electrocardiographic… »
This gene plays a role in the modulation of appetite and the regulation of body fat storage. »
Human LEP wild-type allele is located in the vicinity of 7q31.3 and is approximately 16 kb in length. This allele, which encodes… »
A form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
This gene plays a role in transcriptional regulation via activation of the STAT signal transduction pathway. The gene is also involved in… »
Human LEPR wild-type allele is located within 1p31 and is approximately 212 kb in length. This allele, which encodes leptin receptor protein,… »
A bacterial granulomatous infection caused by Mycobacterium leprae. It is a progressive disease affecting the skin, peripheral nerves, and limbs. If untreated,… »
Leptin (167 aa, ~16 kDa) is encoded by the human LEP gene. This protein is secreted by adipocytes and plays a… »
The determination of the amount of leptin hormone present in a sample. »
Encoded by human LEPR Gene (gp130 Cytokine Receptor Family), five Leptin Receptor isoforms are variously expressed in liver, hypothalamus, heart, small intestine,… »
Having to do with the two innermost meninges (thin layers of tissue that cover and protect the brain and spinal cord). … »
A serious problem that may occur in cancer in which cancer cells spread from the original (primary) tumor to the meninges (thin… »
A serious problem that may occur in cancer in which cancer cells spread from the original (primary) tumor to the meninges (thin… »
A melanoma that arises from leptomeningeal melanocytes. »
A serious problem that may occur in cancer in which cancer cells spread from the original (primary) tumor to the meninges (thin… »
A sarcoma arising from the leptomeninges. »
The two innermost layers of tissue that cover the brain and spinal cord, the arachnoid mater and the pia mater. »
A genus of Gram-negative, aerobic, flexible, spiral-shaped, spirochete with internal flagella in the phylum Spirochaetes. »
A taxonomic family of mostile bacterium in the phylum Spirochaetes that includes the genera Leptospira and Turneriella, among others. »
A contagious bacterial infection caused by spirochetes of the genus Leptospira. Humans are infected by contact with water and soil which have… »
A genus of long filamentous gram-negative anaerobic rod bacteria in the Fusobacteriaceae family; sometimes associated with oral or urogenital infections. »
A species of Gram-negative, anaerobic bacillus in the phylum Fusobacteria. »
An atherosclerotic disorder of the peripheral vascular system affecting mostly males in their later decades. It is caused by thrombotic occlusion of… »
A substance being studied for its ability to stimulate the production of blood cells during chemotherapy. It is a type of colony-stimulating… »
The hydrochloride salt of a 2-piperazinylbenzimidazole-derivative serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Lerisetron specifically binds to 5-HT3 receptors, located… »
A next-generation, pyrazole non-nucleoside reverse transcriptase inhibitor. Lersivirine retains activity against HIV viruses with mutations at position Y181, which confers resistance to… »
An X-linked inherited syndrome caused by mutations in the gene that encodes the enzyme hypoxanthine-guanine phosphoribosyltransferase, resulting in accumulation of uric acid… »
A term referring to the number of anatomic sites affected by a disease. »
The identification of a non-neoplastic or neoplastic pathologic process during the diagnostic work-up of a disease. »
The integer assigned to a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ or body part. … »
A statement about the relative size or order of two objects specifying that an object of interest is smaller than another object… »
A statement about the relative size or order of two objects specifying that either both objects are the same in quantity or… »
Change towards improvement from the pretreatment baseline, but not meeting the criteria for Complete Response or Partial Response in chronic Graft versus… »
Of lower rank, degree, or importance; of reduced size, extent, or degree; more limited in quantity. »
The right border of the stomach. It is concave in shape and extends from the cardiac orifice to the pyloric… »
The double layer of peritoneum that extends from the lesser curvature of the stomach and the start of the duodenum to the… »
A cone-shaped projection in the shaft of the femur in which the iliopsoas muscle is attached. »
The anterior tubercle on the humerus neck where the subscapularis tendon inserts. »
A drug being studied in the treatment of acute leukemias and some other types of cancer. It binds to a protein that… »
A microRNA that has seven isofoms and is known to be a regulator of the RAS oncogene. The length of the miRNA… »
An orally active, tetrahydropyrimidin-2(1H)-one derivative and inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Letaxaban does not affect bleeding… »
A rare congenital disorder, this is the lethal variant of multiple pterygium syndrome, characterized by severe athrogryposis, pterygium, akinesia and often hydrops… »
Lethal(2) giant larvae protein homolog 1 (1064 aa, ~115 kDa) is encoded by the human LLGL1 gene. This protein is involved in… »
A condition marked by drowsiness and an unusual lack of energy and mental alertness. It can be caused by many things, including… »
A drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the treatment of… »
A person who presides over a review committee or panel, which evaluates letters of intent (LOI) for clinical trials. »
A multifocal, multisystem form of Langerhans-cell histiocytosis. There is involvement of multiple organ systems including the bones, skin, liver, spleen, and lymph… »
One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine… »
The determination of the amount of leucine crystals present in a sample. »
Leucine-rich repeat-containing protein 17 (441 aa, ~52 kDa) is encoded by the human LRRC17 gene. This protein is involved in protein-protein… »
Glioma Amplified on Chromosome 1 Protein, encoded by the human GAC1 gene, belongs to the leucine-rich repeat superfamily. This gene was found… »
Domains in DNA-binding proteins that contain amino acid sequences that show periodic arrays of leucine residues. These residues exist in an alpha-helical… »
An orally bioavailable leucine enriched essential amino acid dietary supplement with potential anti-cachexia activity. Leucine-enhanced essential amino acid nutritional supplement may stimulate… »
Predominantly expressed in neural tissues and encoded by human LGI1 Gene, a 557-amino acid 64-kD precursor yields mature 60-kD putative tumor suppressor… »
A leucine-rich protein structural motif that forms an alpha/beta horseshoe tertiary structure. It is composed of repeating units of 20-30 amino acid… »
Leucine-rich repeat and WD repeat-containing protein 1 (647 aa, ~71 kDa) is encoded by the human LRWD1 gene. This protein is involved… »
Leucine-rich repeat serine/threonine-protein kinase 2 (2527 aa, ~286 kDa) is encoded by the human LRRK2 gene. This protein may play a role… »
Leucine-rich repeat transmembrane neuronal protein 2 (516 aa, ~59 kDa) is encoded by the human LRRTM2 gene. This protein may play a… »
Leucine-rich repeat transmembrane protein FLRT3 (649 aa, ~73 kDa) is encoded by the human FLRT3 gene. This protein may play a role… »
Leucine-rich repeat-containing G-protein coupled receptor 5 (907 aa, ~100 kDa) is encoded by the human LGR5 gene. This protein plays a role… »
Leucine-rich repeat-containing protein 19 (370 aa, ~42 kDa) is encoded by the human LRRC19 gene. This protein may play a role in… »
Leucine-rich repeat-containing protein 32 (662 aa, ~72 kDa) is encoded by the human LRRC32 gene. This protein plays a role in the… »
Leucine-rich repeats and immunoglobulin-like domains protein 1 (1093 aa, ~ 119 kDa) is encoded by the human LRIG1 gene. This protein is… »
Leucine-rich repeats and immunoglobulin-like domains protein 3 (1119 aa, ~123 kDa) is encoded by the human LRIG3 gene. This protein may be… »
A genus of gram-positive, nonmotile cocci in the phylum Firmicutes. »
A species of facultatively anaerobic, gram positive, cocci shaped bacteria in the phylum Firmicutes. This species is nonmotile, catalase and oxidase negative,… »
A species of facultatively anaerobic, gram positive, cocci shaped bacteria in the phylum Firmicutes. This species is nonmotile, catalase and oxidase negative,… »
A species of facultatively anaerobic, gram positive, cocci shaped bacteria in the phylum Firmicutes. This species is nonmotile, catalase and oxidase negative,… »
A species of facultatively anaerobic, gram positive, cocci shaped bacteria in the phylum Firmicutes. This species is nonmotile, catalase and oxidase negative,… »
A taxonomic family of Gram positive bacterium in the phylum Firmicutes that includes the genera Fructobacillus and Leuconostoc, among others. »
The active ingredient in a drug used to lessen the toxic effects of substances that block the action of folic acid, especially… »
A drug used to lessen the toxic effects of substances that block the action of folic acid, especially the anticancer drug… »
A chemotherapy combination consisting of methotrexate and leucovorin. »
The sodium salt of leucovorin, an active metabolite of folic acid, used as an antidote to folic acid antagonists. Leucovorin does not… »
Removal of the blood to collect specific blood cells. The remaining blood is returned to the body. »
Cancer that starts in blood-forming tissue, such as the bone marrow, and causes large numbers of abnormal blood cells to be produced… »
Cutaneous involvement by an acute or chronic leukemia. »
History of leukemia after therapy with no evidence on the peripheral blood or bone marrow of leukemia (normalization of all hematologic… »
Leukemia Inhibitory Factor (LIF) affects many systems, including hematopoietic, embryonic, bone, hepatic, neuronal, and fat tissues. LIF induces MHC class I HLA-G… »
Leukemia inhibitory factor receptor protein (1097 aa, 124 kD) is a cell communication process protein that is encoded by the human LIFR… »
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic… »
The determination of the number of leukemic blasts present in a sample. »
The determination of the ratio of leukemic blasts compared to lymphocytes present in a sample. The measurement may be expressed as a… »
Malignant hematopoietic cell originating in the clonal proliferation of myeloid or lymphoid precursor that undergoes an aberrant and poorly regulated process of… »
A malignant hematopoietic cell which may derive from mutations in normal hematopoietic stem cells. Leukemic hematopoietic stem cells can initiate or sustain… »
A serious problem that may occur in leukemia. In leukemic leptomeningitis, cancer cells have spread from the original (primary) tumor to the… »
A serious problem that may occur in leukemia. In leukemic meningitis, cancer cells have spread from the original (primary) tumor to the… »
A usually terminal event in the clinical course of lymphomas. The term indicates the presence of atypical, clonal (malignant) lymphocytes (lymphoma… »
The causation (or induction), development, and progression of a leukaemic disease. »
Leading to or causing leukemia. »
A hematology test result that indicates the presence of an increased white blood cell count and increased neutrophil precursors resembling leukemia, in… »
A drug used to treat several types of leukemias and lymphomas. It blocks cell growth by damaging the cell’s DNA and may… »
A type of blood cell that is made in the bone marrow and found in the blood and lymph tissue. Leukocytes are… »
A rare autosomal recessive immunodeficiency disorder caused by deficiency of CD18 expression. It is characterized by defects in neutrophil adhesion and bacterial… »
A rare immunodeficiency with an autosomal recessive pattern of inheritance. It is caused by mutation in the ITGB2 gene on chromosome 21… »
Leukocyte Adhesion Deficiency, Type II. An inherited disease affecting the metabolism of fucose, which affects the expression of the sialyl Lewis… »
Leukocyte antigen CD37 (281 aa, ~32 kDa) is encoded by the human CD37 gene. This protein is involved in the regulation of… »
Any apoptotic process that is observed in leukocytes. »
The typing, separation, and storage of leukocytes for subsequent transfusion to recipients. »
Cell biology studies concerned with understanding the structure and functioning of leukocytes. »
The determination of the amount of leukocyte cell clumps present in a sample. »
An examination or assessment of the form and structure of white blood cells. »
A test to determine the number of leukocytes in a sample of blood. »
The biological process that refers to the maturation of leukocytes. »
A quantitative measurement of the amount of leukocyte esterase present in a sample. »
Leukocyte immunoglobulin-like receptor subfamily B member 2 (598 aa, ~65 kDa) is encoded by the human LILRB2 gene. This protein is involved… »
Leukocyte Surface Antigen CD47 (323 aa, 35 kD) is a cellular division process protein that is encoded by the human CD47 gene… »
The circulation of white blood cells from the blood stream to tissues or secondary lymphoid organs, to the lymphatics, and back to… »
Leukocyte Trafficking Induction involves initiation of circulation of white blood cells from the blood stream to tissues or secondary lymphoid organs, to… »
Leukocyte Trafficking Inhibition involves interference with, or restraint of, circulation of white blood cells from the blood stream to tissues or secondary… »
Leukocyte migration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind… »
Leukocyte tyrosine kinase receptor (864 aa, ~92 kDa) is encoded by the human LTK gene. This protein plays a role in tyrosine… »
A small vessel vasculitis affecting the skin and/or internal organs. It is characterized by the presence of neutrophils and fibrinoid necrosis in… »
A laboratory test result indicating an increased number of white blood cells in the peripheral blood. »
Localized loss of skin pigmentation, often in patches. »
The leukodystrophies are rare diseases that affect the cells of the brain. Specifically, the diseases affect the myelin sheath, the material that… »
A group of rare genetic neurodegenerative disorders that affect infants and children. These disorders are characterized by metabolic abnormalities in the development… »
White matter changes first described in children with leukemia, associated with radiation and chemotherapy injury, often associated with methotrexate; pathologically characterised by… »
A laboratory test result indicating the presence of nucleated red blood cells and immature leukocytes in the peripheral blood. It is observed… »
Any white discoloration of the nails or nail plates. »
A condition in which there is a lower-than-normal number of leukocytes (white blood cells) in the blood. »
An abnormal patch of white tissue that forms on mucous membranes in the mouth and other areas of the body. It may… »
A clinical term that indicates the presence of a white patch on the buccal mucosa in the mouth which cannot be characterized… »
A clinical term that indicates the presence of a white patch on the surface of the gum which cannot be characterized as… »
A clinical term that indicates the presence of a white patch on the surface of the lip which cannot be characterized as… »
A clinical term that indicates the presence of a white patch on the surface of the tongue which cannot be characterized as… »
A clinical term that indicates the presence of a white patch on the mucosal surface of the vocal cords. In most… »
The hematopoietic process that refers to production of leukocytes in the bone marrow. »
A glycoprotein of 50 kDa secreted by activated natural killer lymphocytes. Leukoregulin shows tumor growth inhibitory activity and enhances membrane permeability and… »
A whitish, viscid discharge from the vagina and uterine cavity. (Dorland, 27th ed) »
Leukosialin (400 aa, ~40 kDa) is encoded by the human SPN gene. This protein is involved in immune cell function. »
A disorder involving the aberrant infiltration and aggregation of leukocytes into the vasculature of the body. Leukostasis is typically detected in the… »
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense… »
Through increased production or release, or inhibited degradation, Leukotriene Activity Induction involves initiation of the biological function of a family of oxidative… »
Through decreased production or release, or enhanced degradation, Leukotriene Activity Inhibition involves interference with, or restraint of, the biological function of a… »
The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and… »
The determination of the amount of the leukotriene B4 in a sample. »
Leukotriene B4 Receptor 1 (352 aa, 38 kD) is a cell motility protein that is encoded by the human LTB4R gene and… »
The determination of the amount of the leukotriene D4 in a sample. »
Leukotriene Degradation consists of conjugation, transport, and/or oxidation of a family of oxidative derivatives of arachidonic acid (5-lipoxygenase pathway) (leukotrienes) having potent… »
The determination of the amount of the leukotriene E4 in a sample. »
Leukotriene Production consists of synthesis of a family of oxidative derivatives of arachidonic acid (5-lipoxygenase pathway) (leukotrienes) having potent regulatory effects on… »
A process that involves the non-covalent binding of leukotrienes to one of three leukotriene receptors. These interactions are involved in neutrophil chemotaxis,… »
A synthetic nonapeptide analogue of gonadotropin-releasing hormone. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Continuous, prolonged administration of leuprolide in… »
A drug used to treat advanced prostate cancer. Under the brand name Lupron, it is also used to treat early puberty in… »
An N-L-leucyl prodrug of the anthracycline doxorubicin, with antineoplastic activity. Leurubicin is converted to its active form doxorubicin in or on tumor… »
A drug used to treat hairy cell leukemia. It is also being studied in the treatment of other types of cancer. Leustatin… »
A non-neoplastic and self-limited condition that occurs during pregnancy. It is characterized by proliferation of luteinized stromal cells that replace the normal… »
An agent that delivers the gene for interleukin-2 (IL-2) into cells to increase production of IL-2 by the cells. »
A short-acting sympathomimetic beta-2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol binds to beta-2 adrenergic receptors in bronchial smooth muscle and activates… »
The hydrochloride salt form of levalbuterol, a relatively selective sympathomimetic beta-2 adrenergic receptor agonist with bronchodilator activity. Levalbuterol hydrochloride binds to beta-2… »
The tartrate salt form of levalbuterol, the R-enantiomer of the short-acting beta-2 adrenergic receptor agonist albuterol, with bronchodilator activity. Levalbuterol selectively binds… »
An antiparasitic drug that is also being studied in cancer therapy with fluorouracil. »
The hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function… »
The oil extracted from the seeds of Gossypium herbaceum. Levant cottonseed oil is a source of gossypol and has antispermacidal activity. … »
The bitartrate salt form of levarterenol, the levorotatory isomer of norepinephrine with a vasoconstrictor effect. Levarterenol binds to alpha and beta-1 receptor… »
A broad, thin muscle originating form the posterior side of the pubis body, spine of the ischium, and pelvic fascia between the… »
A laboratory specimen consisting of the bulbocavernosus and the levator ani. »
A thin, quadrilateral muscle originating at the lower margin of the orbit and attaching to the muscles of the upper lip to… »
A thin, flat, triangular muscle originating from the lesser wing of the sphenoid above and in front of the optic canal and… »
The level of awareness of an organism. »
A formal ranking system of the strength of evidence linked to a reported result. »
Randomized, controlled clinical trial with total mortality as an endpoint. »
Prospective, randomized, controlled trials and meta-analyses of prospective, randomized, controlled trials. »
Prospective, nonrandomized, controlled trials; prospective cohort studies; prospective case series; and cross-sectional studies. »
Opinions of respected authorities based on clinical experience, consensus statements from expert committees, or authoritative reviews. »
Opinion of respected authorities based on clinical experience, descriptive studies, or reports of expert committees. »
A question about an individual's level of social activity. »
A question about an individual's level of support from their friends and family. »
A ranking system used to describe the strength of the results measured in a clinical trial or research study. The design of… »
A drug used to treat seizures (involuntary muscle movements) caused by epilepsy (a group of brain disorders). Levetiracetam is being studied in… »
An acyanotic congenital cardiovascular abnormality characterized by the transposition of the aorta and the pulmonary artery. »
The S-isomer of betaxolol, a selective beta-1 adrenergic receptor antagonist with anti-glaucoma activity and devoid of intrinsic sympathomimetic activity. When applied topically… »
The hydrochloride salt form of levobetaxolol, the S-isomer of the -selective beta-1 adrenergic receptor antagonist betaxolol with anti-glaucoma activity and devoid of… »
A naphthalenone and non-cardioselective adrenergic beta-receptor antagonist with anti-glaucoma activity. Upon administration in the eye, levobunolol blocks beta-adrenergic receptors, thereby causing… »
The hydrochloride salt form of levobunolol, a naphthalenone and non-cardioselective adrenergic beta-receptor antagonist with anti-glaucoma activity. Upon administration in the eye, levobunolol… »
The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and… »
A synthetic piperidine derivative with antihistamine properties. Levocabastine is a second generation histamine-1 receptor antagonist. When applied locally into the eye as… »
The hydrochloride salt form of levocabastine, a synthetic piperidine derivative with antihistaminic properties. Levocabastine is a second generation histamine-1 receptor antagonist. When… »
A condition where the heart is in the correct anatomic position but some or all of the other thoracoabdominal viscera are in… »
A form of carnitine, which is a substance made in muscle and liver tissue and found in certain foods, such as meat,… »
A third generation, non-sedating, selective histamine H1 receptor antagonist, with antihistamine, anti-inflammatory and potential anti-angiogenic activities. Levocetirizine competes with endogenous histamine for… »
The dihydrochloride salt form of the active levorotatory enantiomer of cetirizine, levocetirizine; a third generation, non-sedating, selective histamine H1 receptor antagonist, with… »
An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and… »
A substance used to treat bacterial infections. It belongs to the family of drugs called quinolone antibiotics. »
The L enantiomer of furaltadone, a nitrofuran antibiotic that is effective against bacterial infections in birds when added to feed or drinking… »
The active l-isomer of the racemic mixture of the 5-formyl derivative of tetrahydrofolic acid. Metabolically active, l-leucovorin, also known levoleucovorin, does not… »
A levo isoform of leucovorin calcium with antineoplastic activity. Levoleucovorin is an active metabolite of folic acid, which does not require metabolism… »
A levo isomer of menthol, an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic… »
The hydrochloride salt form of levomethadyl acetate, a synthetic mu-receptor agonist with analgesic activity. Levomethadyl acetate hydrochloride mimics the actions of endogenous… »
A synthetic cannabinoid analogue of delta (9)-tetrahydrocannabinol (delta(9)-THC) with antiemetic and anti-analgesic properties. Although its precise mechanism of action is unknown, levonantradol… »
The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation… »
The hydrochloride salt of levonordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through… »
A form of the hormone progesterone that is made in the laboratory and used to prevent pregnancy. It is being studied in… »
A long-acting, hormone-releasing, intrauterine device consisting of a small, T-shaped, polyethylene frame and a reservoired synthetic progesterone with progestational and potential antineoplastic… »
The ability of an optically active substance to rotate the plane of polarized light counterclockwise (to the left). »
A synthetic derivative of morphine with analgesic activities. Levorphanol mimics the actions of morphine, however, it is about 8 times more potent… »
The tartrate salt form of levorphanol, a synthetic phenanthrene with potent opioid analgesic activity. Levorphanol tartrate mimics the actions of endogenous peptides… »
A synthetic levoisomer of thyroxine (T4), similar to the endogenous hormone produced by the thyroid gland. Thyroxine is de-iodinated to form triiodothyronine… »
The sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid… »
A drug used to treat actinic keratosis (a skin condition that may become cancer). The drug is also being studied in the… »
A drug used to treat actinic keratosis (a skin condition that may become cancer). The drug is also being studied in the… »
Of the large spectrum of 52 histologically different types of tumors, the highest incidence was observed for adenomas of the pituitary and… »
A carbohydrate molecule expressed on the surface of solid tumors including lung, intestinal, breast, prostate, pancreatic, esophageal, stomach, colon, rectal or ovarian… »
Lewis Y Antigen Binding involves non-covalent interaction of a molecule through intermolecular physical forces of attraction with the Lewis Y cell surface… »
Derived from Wistar stock by the laboratory of Dr. Lewis at the Wistar Institute in the 1940s and 1950s, the Lewis is… »
A progressive form of dementia characterized by the presence of protein deposits called Lewy bodies in the midbrain and cerebral cortex, and… »
Lewy body disease is one of the most common causes of dementia in the elderly. Dementia is the loss of mental functions… »
A drug used to treat depression and certain anxiety disorders. It belongs to the family of drugs called selective serotonin reuptake inhibitors… »
A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL-R2 on the surface… »
Provides externalization and support of LexGrid-based terminology software (services, persistence, tooling) developed for the Cancer Biomedical Informatics Grid (caBIG) initiative. The goal… »
An orally bioavailable small-molecule with tubulin-inhibiting, vascular-disrupting, and potential antineoplastic activities. Lexibulin inhibits tubulin polymerization in tumor blood vessel endothelial cells and… »
A unique identifier of a group of lexically equivalent atoms. For English language entries in the Metathesaurus, each string is linked to… »
Cells in the interstitial tissue of the testis that are believed to furnish the internal secretion of that gland. »
A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells… »
This gene may play a role in modulating cell-cell and cell-matrix interactions. »
Human LGALS1 wild-type allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, which encodes… »
This gene is involved in lipid metabolism. »
Human LGALS13 wild-type allele is located in the vicinity of 19q13.1 and is approximately 5 kb in length. This allele, which encodes… »
This gene plays a role in carbohydrate binding. »
Human LGALS3 wild-type allele is located in the vicinity of 14q22.3 and is approximately 21 kb in length. This allele, which encodes… »
This gene plays a role in the modulation of cell-cell and cell-matrix interactions. »
Human LGALS3BP wild-type allele is located within 17q25 and is approximately 9 kb in length. This allele, which encodes galectin-3-binding protein, plays… »
This gene is involved in keratinocyte adhesion and apoptosis regulation. »
Human LGALS7 wild-type allele is located in the vicinity of 19q13.2 and is approximately 3 kb in length. This allele, which encodes… »
This gene plays a role in the regulation of adhesion and apoptosis of keratinocytes. »
Human LGALS7B wild-type allele is located in the vicinity of 19q13.2 and is approximately 3 kb in length. This allele, which encodes… »
This gene is involved in several cellular processes, many of which involve integrin-like cell interactions. »
Human LGALS8 wild-type allele is located within 1q42-q43 and is approximately 31 kb in length. This allele, which encodes galectin-8 protein, plays… »
This gene plays a role in carbohydrate binding. »
Human LGALS9 wild-type allele is located in the vicinity of 17q11.2 and is approximately 20 kb in length. This allele, which encodes… »
An orally-active synthetic aromatic retinoic acid agent with potential antineoplastic and chemopreventive activities. LGD 1550 selectively binds to all three retinoic… »
A drug used to treat skin problems caused by cutaneous T-cell lymphoma that have not gotten better after other treatment. It is… »
This gene plays a role in neural cell function and is involved in the suppression of brain cancer. »
Human LGI1 wild-type allele is located in the vicinity of 10q24 and is approximately 40 kb in length. This allele, which encodes… »
Human LGR5 wild-type allele is located within 12q22-q23 and is approximately 147 kb in length. This allele, which encodes leucine-rich repeat-containing G-protein… »
This gene plays a role in intracellular transport and may be involved in translational regulation. »
Human LGTN wild-type allele is located in the vicinity of 1q32.1 and is approximately 41 kb in length. This allele, which encodes… »
A hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their eggs and to… »
A hormone that stimulates the production of sex hormones in men and women. Also called LHRH and luteinizing hormone-releasing hormone. »
A substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are needed to make… »
A substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In men, this causes… »
LH: The strain exhibits mild hypertension (approx 165mmHg in males and 140mmHg in females at 14 weeks of age in 1984) with… »
The Lhasa Apso has a long, heavy, double coat, draping over his entire body to the floor. This shaggy dog looks like… »
A sensation similar to an electrical shock radiating from the back of the head down the spine as the neck is bent… »
Human LHFP wild-type allele is located in the vicinity of 13q12 and is approximately 261 kb in length. This allele, which encodes… »
A hormone that stimulates the production of sex hormones in men and women. Also called LH-RH and luteinizing hormone-releasing hormone. »
Human LHX1 wild-type allele is located in the vicinity of 17q12 and is approximately 6 kb in length. This allele, which encodes… »
This gene plays a role in transcriptional regulation and has been implicated in the control of differentiation. The gene is also postulated… »
Human LHX2 wild-type allele is located within 9q33-34.1 and is approximately 22 kb in length. This allele, which encodes the LIM/homeobox protein… »
This gene encodes a transcription factor that plays a role in both pituitary development and motor neuron specification. »
Human LHX3 wild-type allele is located in the vicinity of 9q34.3 and is approximately 9 kb in length. This allele, which encodes… »
Human LHX4 wild-type allele is located in the vicinity of 1q25.2 and is approximately 45 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(1;14)(q25;q32) which places the LHX4 gene on the 5' side of the coding… »
A rare, inherited predisposition to multiple cancers, caused by an alteration in the p53 tumor suppressor gene. »
An anticancer drug that promotes differentiation by increasing the levels of retinoic acid within the tumor. »
The orally active fumarate salt of the benzimidazole derivative liarozole with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA),… »
The fumarate salt of an orally-active benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits… »
A long-acting, small polar angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Libenzapril competitively binds to and inhibits ACE, thereby blocking the conversion… »
An object representing a CGAP library; provides access to information about: the tissue sample and its method of preparation, the library protocol… »
Laboratory protocol used to prepare a Library. »
The principles, practice, or study of library administration. »
An immunoradioconjugate containing metuximab, an antibody fragment targeting the hepatocellular cancer (HCC)-associated antigen HAb18G/CD147, that is conjugated to the radioisotope iodine I… »
A taxonomic order of wingless insects that are obligate ectoparasites of birds and mammals. Lice attach tightly to hair, fur, and feathers… »
A social worker trained in psychotherapy who helps individuals deal with a variety of mental health and daily living problems to improve… »
Licensed Practical Nurse - a professional healthcare provider who has graduated from an accredited licensed practical nursing program, has passed the state… »
S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G(1),… »
Licensing Factor Genes encode Licensing Factors that are required, after a prior round of mitosis, in G(1) for DNA replication licensing, are… »
A chronic, recurrent, pruritic inflammatory disorder of unknown etiology that affects the skin and mucus membranes. It presents with rashes and papules… »
A chronic inflammatory process affecting the skin. It is characterized by the presence of white, indurated plaques, epidermal atrophy, and fibrosis of… »
Thickening and hardening of the skin associated with chronic inflammation or irritation. »
Having the characteristics of a chronic, recurrent, pruritic inflammatory disorder of unknown etiology that affects the skin and mucus membranes. It presents… »
A red or violaceous flat-topped, papular eruption that is induced by exposure to a variety of medications or environmental agents. »
An herbal extract derived from the root of the plant Glycyrrhiza glabra with potential anti-inflammatory, antioxidant, and antineoplastic activities. Licorice root extract… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
A substance prepared from dried roots of the plant Glycyrrhiza glabra. It is used as a flavoring in medicines, drinks, and sweets,… »
An autosomal dominant inherited syndrome caused by dysregulation of the amiloride-sensitive sodium channel. It is characterized by early onset hypertension, hypokalemia, metabolic… »
An oral suspension of viscous lidocaine, diphenhydramine (Benadryl) and aluminum and magnesium hydroxides (Maalox). This agent possesses anesthetic, antihistamine, and antacid… »
A substance used to relieve pain by blocking signals at the nerve endings in skin. It can also be given intravenously to… »
The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+… »
A synthetic aminoethylamide with anesthetic activity applied topically to the mucous membranes in the mouth and/or throat. Lidocaine stabilizes the neuronal cell… »
A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application… »
A synthetic aminoethylamide with local anesthetic activity applied topically to either the skin or mucous membranes. Lidocaine stabilizes the neuronal cell membrane… »
Human LIF wild-type allele is located in the vicinity of 22q12.2 and is approximately 6 kb in length. This allele, which encodes… »
The organic phenomenon that distinguishes living organisms from nonliving ones; showing characteristics of life. »
The estimate of the future survival of a subject. »
A unique identifier meant to be a common way to identify and access biologically significant data, whether that data is stored in… »
A designation assigned to a particular period during a life cycle, generally defined by chronological parameters. »
Any medical procedure used to sustain the life of a patient in critical condition. »
A situation that imperils the existence of an entity. »
An adverse event that has life-threatening consequences; for which urgent intervention is indicated; that puts the patient at risk of death at… »
Any adverse event that places the patient, in the view of the initial reporter, at immediate risk of death from the adverse… »
A class of professional or vocational positions of employment that involve life, physical or social sciences. »
Major category of Complementary and Alternative Medicine. This category deals with theories and practices designed to prevent the development of illness, identify… »
The consideration of unspecified lifestyle factors as variables in disease incident, transmission, and control. »
Therapy dealing with lifestyle management and includes: behavioral and dietary modifications, exercise, stress management, and addiction control. This therapy must be used… »
A measure of the risk that a certain event will happen during a person’s lifetime. In cancer research, it is usually given… »
A novel lipid-lowering agent with a complicated mechanism of action. Lifibrol may affect bile acid metabolism, enhance sterol excretion, reduce cholesterol absorption,… »
This gene plays a critical role in cell fate and proliferation in both embryonic and adult cells. »
Human LIFR wild-type allele is located within 5p13-p12 and is approximately 116 kb in length. This allele, which encodes leukemia inhibitory factor… »
A question about lifting or carrying groceries. »
Human LIG1 wild-type allele is located within 19q13.2-q13.3 and is approximately 55 kb in length. This allele, which encodes DNA ligase 1… »
This gene plays a critical role in the regulation of nonhomologous DNA end joining and in V(D)J recombination. »
Human LIG4 wild-type allele is located within 13q33-q34 and is approximately 11 kb in length. This allele, which encodes DNA ligase 4… »
Band of fibrous tissue connecting bone to bone or cartilage to bone thereby supporting or strengthening a joint. »
The fibrous tissues connecting the laminae of neighboring vertebrae beginning at C2 and ending at S1. »
Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that ordinarily… »
A Binding Site Domain is a region of protein that physically interacts stereospecifically, and usually at high affinity, with a specific ligand,… »
General term for proteins that have binding as a major function. »
Ligand Binding Protein Genes encode Ligand Binding Proteins, a large class of diverse proteins for which a major function appears to be… »
A process that involves the detection of and alteration of either the voltage or pH across a membrane, and results in a… »
A process that involves interactions between an intrinsic membrane molecule and an electrochemical gradient across a membrane, often a voltage or a… »
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two… »
Ligase Genes encode Ligases, a large major class of enzymes that catalyze the formation of a linking covalent bond between two substrate… »
Ligatin (584 aa, ~65 kDa) is encoded by the human LGTN gene. This protein plays a role in both translation and phosphoprotein… »
The process of tying off blood vessels so that blood cannot flow to a part of the body or to a… »
A cell located in the collecting tube of the nephron.. »
A condition in which plasma cells secrete immunoglobulin light chains of only one type, kappa or lambda. Light chain deposition disease is… »
A type of cigarette that is claimed to give off less tobacco tar than a regular cigarette when smoked. Light cigarettes have… »
The amount of ambient light/darkness to which a subject is exposed in a period of time. »
A device designed to signal the occurrence of a particular event by activating a light emitting diode. »
A type of diode designed to emit light when a current passes through it. »
20-60 minutes of exercise which elevates your heart rate to 35-60% of your maximum heart rate performed at least 3-4 times per… »
A microscope (device to magnify small objects) in which objects are lit directly by white light. »
Light Microscopy is a technique for producing visible images of structures or details which are too small to be otherwise seen by… »
A low viscosity liquid by-product of the distillation of petroleum consisting of a mixture of alkanes in the C15 to C40… »
Dispersal of a beam of light into a range of directions as a result of physical interactions. »
The treatment of disease with certain types of light. Light therapy can use lasers, LED, fluorescent lamps, and ultraviolet or infrared… »
Work tasks that require little physical or mental effort. »
Treatment with drugs that become active and may kill cancer cells when exposed to light. Light-emitting diode therapy is type of photodynamic… »
An attenuated oncolytic vaccinia virus encoding the light-emitting fusion protein Renilla luciferase-Aequorea green fluorescent protein (RUC-GFP) with potential bioluminescent and antineoplastic… »
The nuclei of precancerous lesions are distinct in that they become enlarged, crowded and hyperchromatic. Light-scattering spectroscopy can diagnose early epithelial… »
A unit of length that would be traversed in a period of one year by an object moving at the speed of… »
A member of a group of substances found in plants that have shown estrogenic and anticancer effects. Lignans have been used in… »
A generally obsolete unit of length used in French speaking countries, equal to 1/12 pouce or 1/40 inch and corresponding closely to… »
A type of dietary fiber for which a complete structure is not well defined in part because the lignin structure itself differs… »
A saturated fatty acid with a 24-carbon backbone. Lignoceric acid occurs naturally in wood tar, various cerebrosides, and in small amount in… »
A question about whether an individual likes or liked the appearance of their body. »
A psychometric scale commonly used in questionnaires where a respondent is asked to evaluate an opinion according to subjective or objective criteria,… »
A subjective score of 1 on a Likert scale. »
A subjective score of 2 on a Likert scale. »
A subjective score of 3 on a Likert scale. »
A subjective score of 4 on a Likert scale. »
A subjective score of 5 on a Likert scale. »
A subjective score of 6 on a Likert scale. »
A subjective score of 7 on a Likert scale. »
A subjective score of 8 on a Likert scale. »
A subjective score of 9 on a Likert scale. »
This gene is involved in immunity. »
Human LILRB2 wild-type allele is located in the vicinity of 19q13.4 and is approximately 7 kb in length. This allele, which encodes… »
LIM and Senescent Cell Antigen-Like Domains 1 protein (325 aa, 32 kD) is a cell maturation protein that is encoded by the… »
LIM and SH3 domain protein 1 (261 aa, ~30 kDa) is encoded by the human LASP1 gene. This protein is involved in… »
The LIM domain is a zinc binding, cysteine rich motif consisting of two tandemly repeated zinc fingers. Unlike GATA type zinc fingers,… »
LIM domain kinase 1 (647 aa, ~73 kDa) is encoded by the human LIMK1 gene. This protein is involved in both actin… »
Encoded by human RIL Gene, 330-aa 35-kDa LIM Domain Protein contains a LIM zinc-binding domain and a PDZ/DHR domain. »
LIM domain-binding protein 1 (411 aa, ~47 kDa) is encoded by the human LDB1 gene. This protein is involved in transcription factor… »
LIM domain-binding protein 2 (373 aa, ~43 kDa) is encoded by the human LDB2 gene. This protein is involved in transcription factor… »
LIM Domains Containing 1 is encoded by the LIMD1 gene. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding… »
LIM homeobox transcription factor 1 beta (379 aa, ~42 kDa) is encoded by the human LMX1B gene. This protein plays a role… »
LIM/homeobox protein Lhx1 (406 aa, ~45 kDa) is encoded by the human LHX1 gene. This protein is involved in the modulation of… »
LIM/homeobox protein Lhx2 (406 aa, ~44 kDa) is encoded by the human LHX2 gene. This protein plays a role in both DNA… »
LIM/homeobox protein LHX3 (397 aa, ~43 kDa) is encoded by the human LHX3 gene. This transcription factor plays a role in pituitary… »
LIM/homeobox protein Lhx4 (390 aa, ~43 kDa) is encoded by the human LHX4 gene. This protein plays a role in the regulation… »
Interdependent positional signaling by the apical ectodermal ridge, the posterior mesenchyme zone of polarizing activity, and the non ridge ectoderm coordinate limb… »
People can lose all or part of an arm or leg for a number of reasons. Common ones include »
A procedure that may be used to deliver anticancer drugs directly to an arm or leg. The flow of blood to and… »
A procedure to avoid amputation of an arm or leg »
A group of autosomal recessive and less frequently autosomal dominant muscular dystrophies affecting the muscles of the hips and shoulders. »
Surgery to remove a tumor in a limb (arm or leg) without removing the whole limb. The bone and tissue around the… »
Surgery to remove a tumor in a limb (arm or leg) without removing the whole limb. The bone and tissue around the… »
A rare disorder characterized by degenerative changes in the limbic area of the brain. Causes include infections and autoimmune conditions; it may… »
A network of structures in the brain involved in memory and emotions. »
This gene is involved in intracellular signaling, which effects several cellular processes during development. »
Human LIMD1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 85 kb in length. This allele, which encodes… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
The oil extracted from the fruit peel of Citrus aurantifolia. Lime oil can be taken as an antioxidant and may help support… »
A question about whether an individual limits or has limited food intake due to swallowing difficulty. »
A switch designed to cut off power automatically to a moving object when it reaches a predetermined point. »
A category for describing factors that limit use of a medical device, medicine or treatment for a specific indication. »
A restriction on the use of a device, medicine or treatment based on parameters set forth by the approver. »
A restriction on the use of a device, medicine or treatment based on time limit parameters set forth by the approver. … »
A response indicating that an individual feels limited a little. »
A response indicating that an individual feels limited a lot. »
An indication that a person's activities are limited by their health condition. »
A business structure used in Europe and Canada, in which shareholder responsibility for company debt is limited to the amount he/she has… »
A question about whether an individual is or was limited in doing leisure or recreational activities because of their neck or… »
A question about whether an individual is or was limited in doing work because of their neck or shoulder. »
A question about whether an individual is or was limited by their ability to lift heavy objects because of their shoulder or… »
A question about whether an individual is or was limited by their ability to lift light objects because of their shoulder or… »
A question about whether an individual is or was limited by their ability to reach above for objects because of their shoulder… »
A question about whether an individual limits or was limited in performing work or daily activities. »
A question about whether an individual limits or was limited in pursuing their hobbies or leisure time activities. »
A type of company, authorized only in certain states, whose owners and managers receive the limited liability and (usually) tax benefits of… »
A business organization with one or more general partners, who manage the business and assume legal debts and obligations, and one or… »
Indicates a biomedical image that is of acceptable quality, with some technical defect but still adequate for diagnostic purposes. »
Cancer therapy using ionizing radiation to < 50% of the body. »
Cancer that is localized in its original site of growth, or involves adjacent lymph nodes but has not spread to other anatomic… »
Small cell lung carcinoma which is confined to one hemi-thorax and the regional lymph nodes. »
Cancer is found in one lung, the tissues between the lungs, and nearby lymph nodes only. »
An electronic device designed to prevent the amplitude of a wave from exceeding a set limit. »
This gene is involved in cytoskeletal modeling and neurotransmission. »
Human LIMK1 wild-type allele is located in the vicinity of 7q11.23 and is approximately 39 kb in length. This allele, which encodes… »
An oral dietary supplement containing a natural cyclic monoterpene and major component of the oil extracted from citrus peels with potential chemopreventive… »
An oral dietary supplement containing a natural cyclic monoterpene and major component of the oil extracted from citrus peels with potential chemopreventive… »
A racemic mixture of limonene, a natural cyclic monoterpene and major component of the oil extracted from citrus rind with chemo-preventive and… »
This gene is essential for cell shape, motility, and survival. »
Human LIMS1 wild-type allele is located within 2q12.3-q13 and is approximately 150 kb in length. This allele, which encodes protein PINCH, is… »
A condition in which abnormal cells are found in the lobules (glands that make milk) of the breast. This condition rarely becomes… »
Lin-28 homolog A (209 aa, ~23 kDa) is encoded by the human LIN28 gene. This protein is involved in enhancing translation. … »
This gene is involved in the enhancement of translation. »
Human LIN28 wild-type allele is located in the vicinity of 1p36.11 and is approximately 19 kb in length. This allele, which encodes… »
This gene plays a role in the suppression of miRNA processing. »
Human LIN28B wild-type allele is located in the vicinity of 6q21 and is approximately 126 kb in length. This allele, which encodes… »
A machine that uses electricity to form a stream of fast-moving subatomic particles. This creates high-energy radiation that may be used to… »
A synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin… »
The acetate salt form of linaclotide, a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which… »
A potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. The inhibition of DPP-4 by linagliptin appears to… »
A lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Linaprazan concentrates highly in the gastric parietal cell canaliculus and on entering… »
A lincosamide antibiotic derived from bacteria Streptomyces lincolnensis with activity against gram positive and anaerobic bacteria. Lincomycin binds to the 50S subunit… »
The hydrochloride salt form of lincomycin, a lincosamide antibiotic originally identified in actinomycete Streptomyces lincolnensis with activity against gram-positive cocci and anaerobic… »
The anhydrous hydrochloride salt form of lincomycin, a lincosamide antibiotic originally identified in actinomycete Streptomyces lincolnensis with activity against gram-positive cocci and… »
Any synthetic or semi-synthetic derivative of lincomycin, first isolated from a soil actinomycete Streptomyces lincolnensis, with antibacterial activity. Lincosamide antibiotics bind to… »
A molecule of RNA 200-17000 nucleotides in length that is transcribed by non-protein coding areas of DNA. These ribonucleotides may play a… »
The gamma-isomer of benzene hexachloride, a colorless to white colored, synthetic, crystalline solid with a slight musty odor that emits toxic fumes… »
A mark that is long relative to its width; a length (straight or curved) without breadth or thickness; the trace of a… »
A code that signifies the end of a line. »
An electronic device designed to improve the output quality of a power source, typically by smoothing the output voltage. »
A line defined by a detector and its collimator in SPECT or by 2 coincident detectors in PET. »
A pair within a sequence of identical pairs of parallel lines of equal thickness, one white and one black. This uniformly alternating… »
A technique in which polymerase chain reaction is used to amplify specific nucleic acid sequences in a biospecimen. The product of this… »
A spatial plot showing values in an image that result from an ideal very narrow line activity concentration source. The abscissa of… »
A unit of length equal 1/12 inch, approximately 2.1167 millimeters. »
A machine that uses electricity to form a stream of fast-moving subatomic particles. This creates high-energy radiation that may be used to… »
Various methods for amplification of nucleic acid sequences by making many copies off the same template. »
A self-reported questionnaire used to measure general well-being and the major domains of quality of life (mental, physical, emotional, social, and spiritual… »
A consequence of a mathematical model in which all parameters appear as separate data coefficients to the first power in the equations… »
The formula to calculate body surface area as described by John D. Current. It is mathematically defined as: BSA (m^2) = 1321… »
An epitope composed of adjacent amino acids »
A round container that has an inner layer of a material different from what the canister is composed of. »
A closure that incorporates a specific molded-in feature such as rings, plugs or flexible sections. These features achieve a seal by conforming… »
A synthetic oxazolidinone derivative, Linezolid selectively inhibits an early step in bacterial protein synthesis and affects blood pressure through monoamine oxidase… »
An artery arising from the external carotid artery between the thyroid and facial arteries that runs under the tongue and becomes the… »
A type of minor salivary gland located on the tongue. »
The lymphoid follicles on the dorsal surface in the posterior region of the tongue. »
A unit of speech such as, a word, suffix, phrase, or sentence. »
A small tongue-like projection from the lower portion of the upper lobe of the left lung. »
An orally bioavailable receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF)… »
A semi-solid with viscosity similar to that of a lotion, which is intended for topical use and must be rubbed into the… »
A rare type of stomach cancer that begins in the lining of the stomach and spreads to the muscles of the stomach… »
A traditional unit of length equal to 1/100 of a Gunter's chain, exactly 7.92 inches or 201.168 mm. »
A traditional unit of length equal to 1/100 of a Ramsden's chain, exactly 1 foot. »
Link Guanine Nucleotide Exchange Factor II, encoded by the Link-GEFII gene, is a Rap guanine nucleotide exchange factor enriched highly in the… »
The textual representation of the linked page. »
Nonrandom association of linked genes; the occurrence of some genes together, more often than would be expected based upon their physical separation,… »
Linkage disequilibrium (LD) mapping is a procedure for determining the non-random association of alleles at two or more loci on a… »
The DNA found between nucleosomes on chromatin; since it is not complexed to proteins as strongly as other forms of DNA, it… »
A regimen comprised of an initial induction regimen, followed by three different consolidation regimens, given on alternating schedule and used for the… »
Typically used in biomedical research, Linker-Oligonucleotides are usually short nucleic acids (DNA) that bridge or link, by complementary base pairing, two nucleic… »
In vitro mutagenesis procedure in which molecules containing 3' and 5' deletion mutations are combined to regenerate an entire DNA region, differing… »
Hyperlinks in documents. »
A guanidine-based insulin secratogogue and structural analogue of pirogliride with hypoglycemic activity. Linogliride blocks ATP-sensitive potassium channels on the membranes of pancreatic… »
The fumarate salt form of linogliride, a guanidine-based insulin secratogogue and structural analogue of pirogliride with hypoglycemic activity. Linogliride blocks ATP-sensitive potassium… »
A polyunsaturated essential fatty acid found mostly in plant oils. It is used in the biosynthesis of prostaglandins and cell membranes. … »
An essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been… »
A formulation of the 6-omega fatty acid derivative 2'-linoleyl carbonate (LOC) conjugated to paclitaxel, a taxane compound extracted from the Pacific yew… »
Linscott's Directory of Immunological and Biological Reagents. No other source in the world tells you where to buy more than 54,000… »
The seed of the flax plant. It is a rich source of omega-3 fatty acid, fiber, and a compound called lignin. It… »
The oil extracted from the seeds of Linum usitatissimum. Linseed oil is used as a nutritional supplement and as a polymerizing… »
An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R,… »
A substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds to CD33, a protein on… »
A drug that is used to treat certain types of muscle spasms and is being studied in the treatment of liver… »
A therapeutic formulation of the primary physiologically active form of endogenous thyroid hormone. In vivo, triiodothyronine enters the nucleus and binds to… »
A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 125. Liothyronine involves many important metabolic functions and is essential… »
A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 131. Liothyronine involves many important metabolic functions and is essential… »
A drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also being studied… »
A clinical finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v7… »
A pathologic finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6… »
A finding about one or more characteristics of lip and oral cavity cancer, following the rules of the TNM AJCC v6 classification… »
A carcinoma arising in the lip or oral cavity. Most oral cavity carcinomas are squamous cell carcinomas of the tongue, buccal… »
A squamous cell carcinoma arising from the lip or the oral cavity. The oral cavity squamous cell carcinoma usually arises from… »
A basal cell carcinoma arising from the lip. »
A malignant epithelial neoplasm arising from the lips. »
A non-neoplastic or neoplastic disorder that affects the lips. Representative examples include inflammation and carcinoma. »
An acute or chronic infectious process affecting the lips. »
A benign or malignant neoplasm involving the lip. »
A squamous cell carcinoma that arises from the lip. It affects males more often than females and it usually involves the… »
Lipase; an enzyme secreted in the digestive tract that catalyzes the breakdown of fats into individual fatty acids that can be absorbed… »
A rare disorder resulting from neoplastic exocrine excess. It is typically seen in 10-15 % of patients with pancreatic acinar cell… »
A laboratory test result which indicates increased levels of lipase in a biologic specimen. »
Human LIPC wild-type allele is located within 15q21-q23 and is approximately 158 kb in length. This allele, which encodes hepatic triacylglycerol lipase… »
A long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to G-CSF, lipegfilgrastim binds to and… »
The determination of the amount of abnormally high concentration of lipid present in a sample. »
A specimen that consists of or contains excessive amounts of fat and fatty substances. »
This gene is involved in the metabolism of high density lipoproteins, triglycerides and phospholipids. »
Human LIPG wild-type allele is located in the vicinity of 18q21.1 and is approximately 32 kb in length. This allele, which encodes… »
A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living… »
Lipid Binding is the molecular interaction between a lipid molecule and a macromolecule (usually protein) for transport, catalysis, localization, or modification of… »
The study of the biochemistry of lipids, including enzyme action. »
The 'test tube' chemical reactions of lipids-not involving enzymes »
A detectable aggregation of lipids or membrane fragments in the cytoplasm. »
A quantitative measurement of the amount of lipids (cholesterol, lipoproteins, and triglycerides) present in a sample. »
Anabolic and catabolic biochemical changes to lipids within a cell as materials needed for important life processes. »
Lipid Metabolism involves anabolic and catabolic biochemical changes to the hydrophobic class of biochemicals within a cell as materials needed for important… »
Nuclear receptors are transcription factors that are activated upon binding to its ligands. Initially, they had been classified as classic endocrine… »
An inherited metabolic disorder that affects the metabolism of the lipids. Representative examples include Gaucher disease, Tay-Sachs disease, and Niemann-Pick disease. … »
The degradation of lipids caused by an oxidative attack from free radicals. »
Lipid phosphate phosphohydrolase 1 (284 aa, ~32 kDa) is encoded by the human PPAP2A gene. This protein plays a role in both… »
Lipid phosphate phosphohydrolase 3 (311 aa, ~35 kDa) is encoded by the human PPAP2B gene. This protein is involved in both cell… »
Sterol-regulatory element binding proteins (SREBPs) play a key role in transcriptional regulation of cholesterol metabolism in response to cholesterol levels in the… »
Any subcellular or molecular event, process, or condition involved in translocation of a lipid macromolecule from one site or compartment to… »
An invasive breast carcinoma characterized by the presence of cytoplasmic neutral lipids in the vast majority of the malignant cells. »
A carcinoma characterized by the presence of malignant epithelial cells with clear cytoplasm which contains neutral lipids. A representative example is the… »
A form of poppy seed oil that contains iodine. Lipiodol is given by injection and builds up in the blood and lymph… »
A drug used to lower the amount of cholesterol in the blood and to prevent stroke, heart attack, and angina (chest… »
An adenoma in which the neoplastic epithelial cells are admixed with adipose tissue cells. »
A rare syndrome characterized by almost complete absence of body fat, accentuated muscularity, insulin-resistant diabetes, hyperlipidemia, hepatomegaly, and hypermetabolism. »
A lipoma usually occuring in the extremities of young children (usually boys). It is characterized by lobules of adipose tissue, separated… »
A benign disorder characterized by the presence of multiple lipoblastomas. »
The determination of the amount of lipocalin-2 present in a sample. »
The determination of the ratio of lipocalin-2 compared to creatinine present in a sample. The measurement may be expressed as a ratio… »
A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
A congenital or acquired disorder characterized by abnormal loss or redistribution of the adipose tissue in the body. »
A rare, slow-growing, painless tumor of infancy and early childhood that usually affects the distal extremities. It is characterized by the presence… »
Hypertrophy of the subcutaneous adipose tissue at the site of multiple subcutaneous injections of insulin. »
A rare, autosomal recessive metabolic disorder characterized by hoarseness of voice, eyelid beading, skin lesions, and seizures. »
Lipoma HMGIC fusion partner (200 aa, ~22 kDa) is encoded by the human LHFP gene. This protein may play a role in… »
Circumscribed expansile neoplasm of adipose origin »
Lipoma-preferred partner (612 aa, ~66 kDa) is encoded by the human LPP gene. This protein may be involved in cell motility or… »
A neoplastic process characterized by poorly circumscribed overgrowth of adipose tissue. »
A tumor composed of mature adipocytes and fibrous tissue infiltrating the epineurium and peripheral nerves. It is often seen at birth… »
A benign hamartomatous lesion composed predominantly of adipose tissue. »
A benign hemangiopericytoma with lipomatous differentiation. »
A benign or malignant tumor composed of adipose (fatty) tissue. -- 2003 »
Any substance that inhibits lipooxygenase, an enzyme that catalyses the dioxygenation of polyunsaturated fatty acids in lipids. Lipooxygenase is involved in the… »
Able to dissolve, be dissolved in, or absorb lipids (fats). »
Lipophilicity represents the affinity of a molecule or a moiety for a lipophilic environment. It is commonly measured by its distribution behavior… »
An endotoxin and biologically active component of the Gram-negative bacterial cell wall that is a Toll-like receptor 4 (TLR4) agonist with potential… »
Lipopolysaccharide-binding protein (481 aa, ~53 kDa) is encoded by the human LBP gene. This protein plays a role in lipopolysaccharide binding. … »
An important class of serum proteins in which a spherical hydrophobic core of triglycerides or cholesterol esters surrounded by an amphipathic monolayer… »
The determination of the amount of lipoprotein a present in a sample. »
Lipoprotein lipase (475 aa, ~53 kDa) is encoded by the human LPL gene. This protein is involved in the metabolism of… »
A rare cancer of the fat cells. »
Large invasive neoplasm of adipose origin »
A drug preparation that contains the active drug inside very tiny, fat-like particles. This form is easier for the body to absorb… »
A liposome-encapsulated formulation of the polyene antifungal antibiotic amphotericin B produced by the bacterium Streptomyces nodosus with antifungal activity. Amphotericin B binds… »
The liposomal formulation of a c-raf-1 antisense oligonucleotide, with potential antineoplastic activity. Liposomal c-raf antisense oligonucleotide targets the translation initiation site of… »
A form of the anticancer drug cytarabine that is contained inside very tiny, fat-like particles. It may have fewer side effects and… »
A liposomal formulation containing a fixed combination of the antineoplastic agents cytarabine and daunorubicin in a 5:1 molar ratio. Liposomal cytarabine-daunorubicin CPX-351… »
A liposome-encapsulated form of the citrate salt of the anthracycline antineoplastic antibiotic daunorubicin. Daunorubicin intercalates into DNA and interacts with topoisomerase II,… »
A formulation of the poorly soluble, semi-synthetic, second-generation taxane docetaxel encapsulated within liposomes, with antineoplastic activity. Upon intravenous administration, docetaxel binds… »
A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
A liposome-encapsulated formulation of the mesylate salt form of eribulin, a synthetic, macrocyclic ketone analogue of halichondrin B, a substance derived from… »
A liposomal nanoparticle-based therapeutic vaccine composed of the cationic lipid R-DOTAP (R-enantiomer of 1,2-dioleoyl-3-trimethylammonium-propane chloride) encapsulating six human papillomavirus 16 (HPV-16) E6… »
A substance composed of active and/or inert ingredient(s) encapsulated in liposomes and intended for injection. »
A plasmid DNA encoding human manganese superoxide dismutase (MnSOD) and liposomally encapsulated with potential chemoprotective activity. When administered orally and localizing in… »
A cancer vaccine comprised of a 43 amino acid epitope from glycoprotein MUC1 (mucin 1) and the synthetic Toll-like receptor 4 (TLR-4)… »
A synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. After displacement… »
The liposomal preparation of oxaliplatin, an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate… »
A form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
A therapeutic preparation consisting of the beta-emitting radioisotope rhenium Re 186 encapsulated in a nanoliposome, with potential antineoplastic activity. Upon intratumoral infusion… »
A form of the anticancer drug irinotecan that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
A form of the anticancer drug vincristine sulfate that is contained inside very tiny, fat-like particles. It may have fewer side effects… »
A formulation of the semisynthetic vinca alkaloid, vinorelbine, encapsulated within liposomes, with antineoplastic activity. Vinorelbine binds to tubulin and prevents formation of… »
A type of nanoparticle made of lipids, or fat molecules, surrounding a water core. Liposomes, several of which are widely used to… »
A microscopic vesicle consisting of one or more phospholipid layers surrounding an aqueous core. Liposomes can be utilized to facilitate the delivery… »
A form of the anticancer drug doxorubicin citrate that is contained inside very tiny, fat-like particles. It is being studied in the… »
A form of the anticancer drug irinotecan hydrochloride that is contained inside very tiny, fat-like particles. It is being studied in the… »
A liposomal formulation containing a nucleotide that mimics the human tumor suppressor microRNA (miRNA) miR-34, with potential antineoplastic activity. Upon administration, liposome-encapsulated… »
A systemic gene therapy anti-cancer agent composed of cationic liposomes, which encapsulates plasmid DNA encoding for the tumor suppressor gene RB94 and… »
A topical hydrophilic gel containing a recombinant form of the human Cu/Zn superoxide dismutase (SOD1), a cytoplasmic antioxidant enzyme, encapsulated in liposomes… »
A liposomal formulation containing the antisense oligodeoxynucleotide (ODN) growth factor receptor-bound protein 2 (Grb2), with potential antineoplastic activity. Upon administration, liposome-incorporated Grb2… »
Encapsulation of DNA within a lipid bilayer with subsequent introduction into a cell by fusion of the liposome with the cell… »
A form of the anticancer drug paclitaxel that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
Liprin-beta-1 (1011 aa, ~114 kDa) is encoded by the human PPFIBP1 gene. This protein plays a role in the mediation of protein-protein… »
A solid or semi-solid with a waxy consistency in the shape of a stick and intended for use on the lips. … »
A test done on a sample of blood to look for cancer cells from a tumor that are circulating in the blood… »
A sterilization process to kill microorganisms using a liquid sterilant. »
A type of chromatography in which separation of a mixture is achieved by passing a sample in a stream of liquid solvent… »
LC/MS is a hyphenated technique, combining the separation power of liquid chromatography (LC), an analytical chromatographic technique for separating ions or molecules… »
A substance in the fluid state of matter having no fixed shape but a fixed volume. »
A capsule composed of liquid covered with an outer shell, which is usually prepared from gelatin. »
A process that fills a dosage unit with a liquid in a method not otherwise specified. »
Nitrogen in a liquid state, having been super-cooled to about -200 degrees Celsius. »
A solution or suspension composed of an anionic surfactant used for cleansing. »
A method of preparing cervical samples for examination in the laboratory. A sample is collected using a spatula or brush and then… »
A type of Pap test. A Pap test is a procedure in which cells are scraped from the cervix for examination under… »
An alcoholic beverage in which the initial fermentation mixture is distilled in order to concentrate the alcohol, generally resulting in a mixture… »
A long-acting, fatty acylated glucagon-like peptide-1 (GLP-1) analog administered subcutaneously, with antihyperglycemic activity. Liraglutide's prolonged action and half-life of 11-15 hours are… »
A thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in… »
A prodrug of the d-isomer of amphetamine, a non-catecholamine sympathomimetic amine with central nervous system (CNS) stimulating activity. Upon administration, lisdexamphetamine is… »
The dimesylate form and prodrug of the d-isomer of amphetamine, a non-catecholamine sympathomimetic amine with central nervous system (CNS) stimulating activity. Upon… »
A drug used to treat high blood pressure and certain heart conditions. It is also being studied in the prevention and treatment… »
The anhydrous form of the long-acting angiotensin-converting enzyme (ACE) inhibitor lisinopril with antihypertensive activity. Lisinopril, a synthetic peptide derivative, competitively binds to… »
A drug that may protect healthy cells from chemotherapy and radiation without inhibiting the effects of these therapies on tumor cells. … »
A rare genetic brain malformation characterized by smooth folds and grooves in the brain. There are approximately 20 different types of lissencephaly… »
A data acquisition approach in which detector counts are stored sequentially as scan time progresses. This contrasts with the much more compact… »
A 12 category life events questionnaire designed to assess the quality of life of a patient before, during and following stressful life… »
A species of facultatively anaerobic, Gram positive, rod shaped bacteria in the phylum Firmicutes. This species is motile, catalase positive, oxidase and… »
Listeriosis is a foodborne illness caused by Listeria monocytogenes, bacteria found in soil and water. It can be in a variety… »
A species of facultatively anaerobic, Gram positive, rod shaped bacteria in the phylum Firmicutes. This species is motile by flagella and pilli,… »
A species of facultatively anaerobic, Gram positive, rod shaped bacteria in the phylum Firmicutes. This species is catalase positive, oxidase negative, nonsporulating,… »
A species of facultatively anaerobic, Gram positive, rod shaped bacteria in the phylum Firmicutes. This species is motile by up to four… »
A species of facultatively anaerobic, Gram positive, rod shaped bacteria in the phylum Firmicutes. This species is motile by peritrichous flagella, asporogenous,… »
A species of facultatively anaerobic, Gram positive, rod shaped bacteria in the phylum Firmicutes. This species is motile by peritrichous flagella, asporogenous,… »
A taxonomic family of Gram positive bacterium in the phylum Firmicutes that includes the genera Listeria and Brochothrix, among others. »
A bacterial infection caused by Listeria monocytogenes. It occurs in newborns, elderly, and immunocompromised patients. The bacteria are transmitted through ingestion of… »
A measure of volume for a liquid, using the metric system. One liter is equal to 1,000 cubic centimeters (cc), 1,000 milliliters… »
A metric unit of volumetric flow rate defined as the rate at which one liter of matter crosses a given surface during… »
Liters per gram per day. »
Liters per gram per hour. »
Liters per gram per minute. »
Liters per gram per second. »
A non-SI unit of volumetric flow rate defined as the rate at which one liter of matter crosses a given surface during… »
A unit expressed as one liter of volume per unit of time equal to one hour per square meter of area. … »
A dose calculation unit expressed in liter(s) per kilogram. »
Liters per kilogram per second. »
A measure of volume concentration expressed as the number of liters of a dissolved substance per liter of solution. »
Liters per microgram per day. »
Liters per microgram per hour. »
Liters per microgram per minute. »
Liters per microgram per second. »
Liters per micromole per day. »
Liters per micromole per hour. »
Liters per micromole per minute. »
Liters per micromole per second. »
Liters per milligram per day. »
Liters per milligram per hour. »
Liters per milligram per minute. »
Liters per milligram per second. »
Liters per millimole per day. »
Liters per millimole per hour. »
Liters per millimole per minute. »
Liters per millimole per second. »
A metric unit of volumetric flow rate defined as the rate at which one liter of matter crosses a given surface during… »
A unit expressed as one liter of volume per unit of time equal to one minute per square meter of area. … »
Liters per mole. »
Liters per mole per day. »
Liters per mole per hour. »
Liters per mole per minute. »
Liters per mole per second. »
Liters per nanogram per day. »
Liters per nanogram per hour. »
Liters per nanogram per minute. »
Liters per nanogram per second. »
Liters per nanomole per day. »
Liters per nanomole per hour. »
Liters per nanomole per minute. »
Liters per nanomole per second. »
Liters per picogram per day. »
Liters per picogram per hour. »
Liters per picogram per minute. »
Liters per picogram per second. »
A metric unit of volumetric flow rate defined as the rate at which one liter of matter crosses a given surface during… »
A soft metal. Lithium salts are used to treat certain mental disorders, especially bipolar (manic depressive) disorder. Lithium salts include lithium carbonate… »
The lithium salt form of benzoic acid with diuretic and urinary antiseptic activity. Lithium benzoate exerts natriuretic activity and disinfects the urinary… »
The carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium interferes with transmembrane sodium exchange in nerve… »
A monovalent cation that is metabolized much like sodium and is important in many cellular functions inside or on the surface of… »
The citrate salt of lithium, a monovalent cation with antimanic activity. Although the exact mechanism is unclear, lithium might exert its mood-stabilizing… »
Congenital abnormalities, mainly cardiovascular malformations, which develop in a fetus when the mother uses lithium medication during pregnancy. »
A battery consisting of a lithium anode and a cathode of iodine and poly-2-vinyl pyridine. They are especially useful in devices like… »
A procedure to break a stone into small particles that can be more easily cleared from the body. »
An inhibitor of the kinesin-related motor protein Eg5 with potential antineoplastic activity. Litronesib selectively inhibits the activity of Eg5, which may result… »
