Medicine
A skin care treatment system consisting of a cytokine-containing milk-based cooling gel and a cytokine-containing milk-based soothing lotion with hydrating and potential… »
A substance that is being studied for its ability to make cancer cells respond to drugs to which they have become… »
Sustancia en estudio por su capacidad de hacer que las células cancerosas respondan a los medicamentos a los que se han vuelto… »
A substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to… »
Sustancia en estudio para el tratamiento de la leucemia mieloide aguda (LMA) y otros tipos de cáncer. Es un tipo de inhibidor… »
A human monoclonal antibody being studied in the treatment of several types of cancer. Monoclonal antibodies are made in the laboratory and… »
Anticuerpo monoclonal humano en estudio para el tratamiento de varios tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y… »
This virus is a spontaneous mutant of SV7, a molecular clone of MoMuSV124. Like SV7, R7 induces subcutaneous fibrosarcomas, spleen tumors, and… »
Sustancia en estudio para el tratamiento de cáncer y ciertas otras enfermedades, como la artritis reumatoide. Puede bloquear las señales… »
A substance being studied in the treatment of cancer and certain other diseases, such as rheumatoid arthritis. It may block tumor cell… »
Término que describe las células que tienen una proteína que se une a los andrógenos (hormonas masculinas). Las células cancerosas que son… »
Rab GTPase-binding effector protein 1 (862 aa, ~99 kDa) is encoded by the human RABEP1 gene. This protein is involved in both… »
The eukaryotic cell contains compartments with distinct functions bounded by lipid bilayer membranes. The movement of membrane vesicles between these compartments… »
This gene is involved in intracellular membrane trafficking. »
Human RAB23 wild-type allele is located in the vicinity of 6p11 and is approximately 33 kb in length. This allele, which encodes… »
This gene may be involved in protein ubiquitination and secretory vesicle transport. »
Human RAB40B wild-type allele is located in the vicinity of 17q25.3 and is approximately 44 kb in length. This allele, which encodes… »
This gene plays a role in GTP hydrolysis. »
Human RAB5C wild-type allele is located in the vicinity of 17q21.2 and is approximately 30 kb in length. This allele, which encodes… »
RAB8 protein (MEL) contains the four GTP/GDP-binding sites present in all RAS proteins. The putative effector-binding site of MEL is similar… »
This gene plays a role in signal transduction and protein trafficking. »
Human RAB8A wild-type allele is located in the vicinity of 19p13.1 and is approximately 23 kb in length. This allele, which encodes… »
Hueso pequeño en la base de la columna vertebral. Está formado por la fusión de 3 a 5 huesos soldados. También se… »
A courtesy title of respect for the leader of a Jewish congregation, the chief religious official of a synagogue, or a Jewish… »
Cáncer que se forma en el tejido blando de un tipo de músculo llamado músculo estriado. El rabdomiosarcoma se puede presentar en… »
Tumor de tejido blando que es sumamente común en los niños mayores y adolescentes. Empieza en las células musculares embrionarias… »
Tumor del tejido blando que es más común en los lactantes y los niños pequeños. Empieza en los músculos, habitualmente en la… »
This gene is involved in the regulation of both GTPase activity and endocytosis. »
Human RABEP1 wild-type allele is located in the vicinity of 17p13.2 and is approximately 104 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(5;17)(q33;p13) which fuses most of the RABEP1 gene with the 3' part of… »
A fusion protein (1318, ~150 kDa) encoded by the RABEP1/PDGFRB fusion gene. This protein is comprised of 85% of the Rab GTPase-binding… »
An alpha-pyridylmethylsulfinyl benzimidazole and a selective and irreversible proton pump inhibitor with antisecretory property. Rabeprazole enters the parietal cell and accumulates in… »
The sodium salt of the prodrug rabeprazole, a substituted benzimidazole proton pump inhibitor, with potential anti-ulcer activity. After protonation, accumulation, and transformation… »
Enfermedad del sistema nervioso causada por el virus de la rabia. La rabia se caracteriza por amento de la producción de saliva,… »
A disease of the nervous system caused by the rabies virus. Rabies is marked by an increase in saliva production, abnormal behavior,… »
A species of enveloped, rod- or bullet-shaped viruses in the Rhabdoviridae family and Lyssavirus genus. The genome is composed of single-stranded, negative-sense… »
An inhibitor of the cell cycle checkpoint kinase 2 (chk2) with potential chemopotentiating activity. Rabusertib binds to and inhibits the activity of… »
RAC-alpha serine/threonine-protein kinase (480 aa, ~56 kDa) is encoded by the human AKT1 gene. This protein is involved in signal transduction, serine/threonine… »
RAC-beta serine/threonine-protein kinase (481 aa, ~56 kDa) is encoded by the human AKT2 gene. This protein is involved in protein phosphorylation, glucose… »
RAC-beta serine/threonine-protein kinase (479 aa, ~56 kDa) is encoded by the human AKT3 gene. This protein plays a role in protein phosphorylation,… »
Rac-1 is a small G-protein in the Rho family that regulates cell motility in response to extracellular signals. Several changes in… »
Human RAC1 wild-type allele is located in the vicinity of 7p22 and is approximately 29 kb in length. This allele, which encodes… »
Human RAC3 wild-type allele is located in the vicinity of 17q25.3 and is approximately 3 kb in length. This allele, which encodes… »
An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical… »
A coded value specifying a self-declared racial origination, independent of ethnic origination. »
A social environmental measure of neighborhood race and/or ethnic residential segregation based on data from the U.S. Census Bureau. »
The racemic form of a synthetic quinoxaline phenoxypropionic acid derivative with antineoplastic properties. XK469R selectively inhibits topoisomerase II by stabilizing the enzyme-DNA… »
A condition in children in which bones become soft and deformed because they don’t have enough calcium and phosphorus. It is caused… »
An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb… »
Any sport where players use racquets to hit a ball or other object. »
A unit of radiation absorbed dose equal to the amount of energy from any type of ionizing radiation (e.g., alpha, beta, gamma,… »
A substance that has been studied in the treatment of some types of cancer. rAd/p53 is a weakened adenovirus that carries the… »
Sustancia que se estudió para el tratamiento de algunos tipos de cáncer. El rAd/p53 es un adenovirus atenuado que lleva el gen… »
A drug used with another drug to treat some postmenopausal women with advanced breast cancer that is hormone-receptor positive and HER2… »
Medicamento que se usa con otro fármaco para tratar a algunas mujeres posmenopáusicas con cáncer de mama en estadio avanzado que es… »
This gene is involved in cell cycle regulation and DNA repair. »
Human RAD17 wild-type allele is located in the vicinity of 5q13 and is approximately 46 kb in length. This allele, which encodes… »
This gene plays a role in both protein ubiquitination and DNA repair. »
Human RAD18 wild-type allele is located within 3p25-p24 and is approximately 188 kb in length. This allele, which encodes E3 ubiquitin-protein ligase… »
This gene is involved in chromosomal cohesion, DNA repair and apoptosis. »
Human RAD21 wild-type allele is located in the vicinity of 8q24 and is approximately 29 kb in length. This allele, which encodes… »
This gene is involved in both nucleotide excision repair and the regulation of protein degradation. »
Human RAD23A wild-type allele is located in the vicinity of 19p13.2 and is approximately 8 kb in length. This allele, which encodes… »
This gene is involved in DNA excision repair. »
Human RAD23B wild-type allele is located in the vicinity of 9q31.2 and is approximately 49 kb in length. This allele, which encodes… »
This gene plays a role in DNA double-strand break repair. »
Human RAD50 wild-type allele is located in the vicinity of 5q31 and is approximately 89 kb in length. This allele, which encodes… »
The RAD51 family of related genes, identified in both yeast and humans, encode strand-transfer proteins thought to be involved in recombinational repair… »
This gene is involved in both homologous recombination and repair of DNA. »
Encoded by human RAD51C Gene (RECA Family, RAD51 Subfamily), the 376-amino acid 42 kD RAD51 Homolog C is a probable nuclear protein… »
Human RAD51 wild-type allele is located in the vicinity of 15q15.1 and is approximately 37 kb in length. This allele, which encodes… »
This gene plays a role in the mediation of homologous recombinational repair of DNA. »
Human RAD51B wild-type allele is located within 14q23-q24.2 and is approximately 776 kb in length. This allele, which encodes DNA repair protein… »
A fusion gene that results from a chromosomal translocation t(12;14)(q14-15;q22-24) which fuses exon 5, 7, 9 or 10 of the RAD51B gene… »
A fusion protein encoded by the RAD51B/HMGA2 fusion gene. This protein is comprised of the N-terminal region of the DNA repair protein… »
This gene plays a role in DNA repair and meiotic recombination. »
Human RAD51C wild-type allele is located within 17q22-q23 and is approximately 3 kb in length. This allele, which encodes DNA repair protein… »
This gene is involved in both double-strand break repair and homologous recombination. »
Human RAD52 wild-type allele is located within 12p13-p12.2 and is approximately 79 kb in length. This allele, which encodes DNA repair protein… »
RAD54-Like Protein (RAD54L), encoded by the RAD54L gene, belongs to the DEAD-like helicase superfamily. RAD54L plays a role in homologous recombination related… »
This gene plays a role in DNA repair and mitotic/meiotic recombination. »
Highly expressed in testis and spleen by human RAD54B Gene (SNF2/SWI2 Family), the two isoforms of 910-aa 100-kD nucleoplasmic RAD54B Homolog exhibit… »
Human RAD54B wild-type allele is located within 8q21.3-q22 and is approximately 103 kb in length. This allele, which encodes DNA repair and… »
This gene plays a role in the homologous recombination of double-strand DNA breaks. »
Human RAD54L wild-type allele is located within 1p32 and is approximately 31 kb in length. This allele, which encodes DNA repair and… »
This gene plays a role in both cell cycle checkpoint control and DNA repair. »
Human RAD9A wild-type allele is located within 11q13.1-q13.2 and is approximately 7 kb in length. This allele, which encodes cell cycle checkpoint… »
This gene is involved in both DNA repair and cell cycle progression. »
Human RAD9B wild-type allele is located in the vicinity of 12q24.11 and is approximately 30 kb in length. This allele, which encodes… »
Energía que se libera en forma de partículas u ondas electromagnéticas. Las fuentes comunes de radiación incluyen el gas radón, los rayos… »
Tipo de radioterapia que usa partículas minúsculas llamadas neutrones fabricadas por una máquina llamada ciclotrón. »
Cantidad de radiación que es mayor que la que se aplica en la radioterapia habitual. La radiación de dosis alta se dirige… »
Radiación que se compone tanto de campos eléctricos como magnéticos. Surge de fuentes naturales o producidas por el hombre. La fuerza de… »
Tipo de radiación administrada (o emitida) durante procedimientos con rayos X, por sustancias radiactivas, por rayos que entran la atmósfera terrestre desde… »
Sistema que se usa para aplicar radioterapia interna a los pacientes de cáncer de mama después de la cirugía para extirpar su… »
Tipo de radioterapia para la cual se inyecta en la sangre una sustancia radiactiva (por ejemplo, un anticuerpo monoclonal marcado radiactivamente). Esta… »
Rayos invisibles que forman parte de la energía que viene del sol. La radiación ultravioleta que llega a la superficie de la… »
Rayos invisibles que forman parte de la energía que viene del sol. La radiación ultravioleta A también proviene de lámparas solares y… »
Rayos invisibles que forman parte de la energía que viene del sol. La radiación ultravioleta B causa quemaduras de sol, oscurecimiento y… »
Rayos invisibles que son partes de la energía que viene del sol. La capa de ozono impide que la mayor parte de… »
Rayos invisibles que forman parte de la energía que viene del sol. La radiación UV que llega a la superficie de la… »
Rayos invisibles que forman parte de la energía que viene del sol. La radiación UVA también proviene de lámparas solares y camillas… »
Rayos invisibles que forman parte de la energía que viene del sol. La radiación UVB causa quemaduras de sol, oscurecimiento y engrosamiento… »
Rayos invisibles que son partes de la energía que viene del sol. La capa de ozono impide que la mayor parte de… »
Que emite radiación. »
Arranged like rays or radii; radiating from a common center or moving in the direction of a radius; relating to or near… »
The branch of the brachial artery that passes down the forearm. »
Arteries that arises from the arcuate arteries in the myometrium and supply small straight arteries to the basal layer of the endometrium… »
An artery arising from the brachial artery just below the bend of the elbow with numerous branches in the forearm, wrist and… »
Traumatic or pathological injury to the radius bone in which the continuity of the bone is broken. »
A congenital deformity characterized by the presence of hypoplastic radius. It is usually associated with club hand deformity. »
A large nerve that arises from the brachial plexus and enervates the extensor muscles and skin of the entire upper limb's posterior… »
A benign breast lesion characterized by the presence of fibrosis with stellate appearance in the parenchyma. The lesions are often multiple… »
A vein that ascends on the radial side of the forearm to drain blood from the palm of the hand. The radial… »
A SI-derived unit of plane angle measurement defined and named by James Thomson in 1873. One radian is the plane angle between… »
A unit of angular acceleration defined as the change in angular velocity equal to one radian per second per second. »
A process that removes water or volatile solvents from a bed of solids by relying on absorption of heat radiation by those… »
A sensation of discomfort or distress that spreads from one anatomic location to another. »
Energy released in the form of particle or electromagnetic waves. Common sources of radiation include radon gas, cosmic rays from outer space,… »
The path or area of the body covered by a moving source of radiation during treatment. »
The study of the mechanisms and biological effects of ionizing radiation, including repair processes. »
The study of the mechanisms and biological effects of electromagnetic fields. »
The study of the mechanisms and biological effects of low level ionizing radiation. »
The study of the effects of radiation on living organisms. »
A type of radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near… »
A burn caused by exposure to x-ray, radium, sunlight, atomic or any other type of radiant energy. »
Inflammation of the lining of the bladder caused by radiation therapy to the pelvis, including the bladder. Symptoms include pain and a… »
Issue associated with the device causing unintended therapeutic action to an area of the body other than the intended area. »
A skin condition that is a common side effect of radiation therapy. The affected skin becomes painful, red, itchy, and blistered. … »
A unit of measurement of the dose of radiation received or absorbed. »
The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by scintillation counting. »
Radiation is a type of energy. People are exposed to small amounts of radiation every day from sources such as sunlight. A… »
Inflammation of the small intestine caused by radiation therapy to the abdomen, pelvis, or rectum. Symptoms include nausea, vomiting, abdominal pain and… »
Radiation is energy that travels in the form of waves or high-speed particles. It occurs naturally in sunlight. Man-made radiation is used… »
The formation of scar tissue as a result of radiation therapy. »
The area of the body exposed to radiation during radiation therapy. »
Damage to DNA caused by ionizing radiation. Can cause base change mutations or strand breakage. »
Radiation Interaction involves the interaction of a stream of subatomic particles or transmitted energy waves (such as electromagnetic radiation) with a biological… »
The use of ionizing radiation to kill cancer cells »
A technique for medical imaging that uses ionizing radiation like X-rays and gamma rays. Both x-rays and gamma rays are high energy,… »
The death of healthy tissue caused by radiation therapy. Radiation necrosis is a side effect of radiation therapy given to kill cancer… »
The use of non-ionizing radiation such as X-rays to obtain internal images of the body »
A health professional who specializes in caring for people who are receiving radiation therapy. »
A doctor who specializes in using radiation to treat cancer. »
The study of the effects of ionizing radiation for treatment of tumors. »
Issue associated with excessive radiation emitted from radiological or diagnostic device. »
A person who makes sure that the radiation machine delivers the right amount of radiation to the correct site in the… »
The scientific discipline of the application of physics to the use of ionizing radiation in therapy and in diagnostic radiology; including, by… »
Serious illness caused by being exposed to high doses of certain types of radiation, usually over a short period of time. Symptoms… »
A program within the National Cancer Institute (NCI) that is responsible for the clinically-related extramural radiation research program. It establishes priorities, allocates… »
The ability of some cells or tissues to withstand ionizing radiation without serious injury. Tolerance depends on the species, cell type, and… »
Serious illness caused by being exposed to high doses of certain types of radiation, usually over a short period of time. Symptoms… »
Serious illness caused by being exposed to high doses of certain types of radiation, usually over a short period of time. Symptoms… »
A sterilization process that uses radiation such as electron beams, X-rays, gamma rays, or subatomic particles to kill microorganisms. »
A type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of… »
A health professional who gives radiation treatment. »
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation… »
A multi-institutional cooperative organization, a national cancer study research group comprised of 250 of the major research institutions nationally and in Canada,… »
Issue associated with too little radiation emitted from radiological or diagnostic devices. Results in insufficient production of normal image contrast. »
Techniques used for altering the genetic material of an organism by exposure to ionizing radiation. »
A cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation. »
Radiation-Induced Gene Expression involves activation or enhanced activity in the expression of a gene as a result of radiation. »
A meningioma that arises within the cranial cavity and results from exposure to radiation. »
Any recombination occuring in response to DNA breakage induced by ionizing radiation, and resolved with possible exchange and frequent loss of segments… »
Inflammation of the mouth mucosa caused by head and neck radiation therapy. Signs and symptoms include dry mouth due to lack… »
Acute skin inflammatory reaction caused by drugs, especially chemotherapeutic agents, weeks or months following radiotherapy. The inflammatory reaction is confined to the… »
A malignant vascular neoplasm arising in an anatomic site exposed to radiation therapy. »
A non-neoplastic or neoplastic disorder which results from exposure to radiation. Examples of non-neoplastic disorders include dermatitis, enteritis, stomatitis, pneumonitis, and… »
radiation induced progressive, malignant disease of the blood forming organs. »
Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation. »
A high grade osteosarcoma arising in an irradiated bone. »
A sarcoma that arises in the bones or soft tissues following exposure to ionizing or non-ionizing radiation. »
A particle which carries a positive or negative electrical charge, typically an ionized atom or molecule, or an electron. »
Diagnostic or therapeutic use of non-ionizing radiation »
Directed to the root or source of a morbid process; to remove the root of a disease or all diseased tissue, as… »
Surgery to remove the cervix, nearby tissue and lymph nodes, and the upper part of the vagina. It may be used to… »
Surgery to remove all of the bladder (the organ that holds urine) as well as nearby tissues and organs. »
The simultaneous surgical resection of the urinary bladder and prostate gland with pelvic lymphadenectomy. »
Tipo de molécula inestable que contiene oxígeno y que reacciona fácilmente con otras moléculas de la célula. Una acumulación de… »
Surgery to remove the uterus, cervix, and part of the vagina. The ovaries, fallopian tubes, and nearby lymph nodes may also be… »
Tipo de molécula inestable que se elabora durante el metabolismo normal de las células (cambios químicos que ocurren en una célula). … »
Surgery to remove a tumor and a large amount of normal tissue surrounding it. Nearby lymph nodes may also be removed. … »
A surgical procedure to remove most or all of the lymph nodes that drain lymph from the area around a tumor. The… »
Surgery for breast cancer in which the breast, chest muscles, and all of the lymph nodes under the arm are removed. For… »
A surgical procedure in which all the ipsilateral cervical lymph node groups of the neck, internal jugular vein, sternocleidomastoid muscle, spinal accessory… »
Surgery to remove an entire kidney, nearby adrenal gland and lymph nodes, and other surrounding tissue. »
Surgery to remove all of the prostate through an incision between the scrotum and the anus. Nearby lymph nodes are sometimes removed… »
Surgery to remove the entire prostate and some of the tissue around it. Nearby lymph nodes may also be removed. In a… »
Surgery to remove all of the prostate and nearby lymph nodes through an incision in the wall of the abdomen. »
Surgery to remove the cervix, nearby tissue and lymph nodes, and the upper part of the vagina. It may be used to… »
A therapeutic surgical procedure that involves the removal of the posterior and superior walls of the external auditory canal, the remnants of… »
Surgery to remove the entire vulva (the external female genital organs, including the clitoris, vaginal lips, and the opening to the vagina)… »
A macrocyclic antifungal antibiotic that inhibits signal-dependent transcriptional activation and induces differentiation in leukemia. »
A macrocyclic antifungal antibiotic, radicicol oxime derivative that binds and selectively depletes heat shock protein 90 (Hsp90) chaperone, a signaling molecule involved… »
A novel oxime derivative of radicicol that destabilizes the hsp90 client proteins, such as erbB2, raf-1 and AKT, which are essential for… »
An inflammatory process affecting a nerve root. Patients experience pain radiating along a nerve path because of spinal pressure on the nerve… »
A tracking system that monitors the position of the target organ or tissue in real-time in order to spare surrounding tissues from… »
An electromagnetic wave frequency between audio and infrared. »
A type of wave made when an electric field and a magnetic field are combined. Radio waves are being studied in the… »
Giving off radiation. »
Parameter used to quantify radioactivity and represents radioactive source transformations, i.e. disintegrations or emissions, per unit time. »
A drug that contains a radioactive substance and is used to diagnose or treat disease, including cancer. Also called radiopharmaceutical. »
Elements which exhibit atomic emission due to natural or artificial nuclear transformation. These elements spontaneously undergo radioactive decay. »
Airborne radioactive particles that fall to the ground during and after an atomic bombing, nuclear weapons test, or nuclear plant accident. … »
A radioactive form of glucose (sugar) often used during a positive emission tomography (PET) scan, a type of imaging test. In PET,… »
Implantation of radioactive material in an internal anatomic site. »
A radioactive form of iodine, often used for imaging tests or to treat an overactive thyroid, thyroid cancer, and certain other… »
A substance containing a radioisotope that has an affinity for and binds to a chosen biologic substance of interest to enable quantification… »
A radioactive form of palladium (a metallic element that resembles platinum). When used to treat prostate cancer, radioactive seeds (small pellets that… »
A small, radioactive pellet that is placed in or near a tumor. Cancer cells are killed by the energy given off as… »
A dosing unit in a form of an incapsulated radioactive material that constitutes an implantable pellet designed for brachytherapy administration. »
Classical technique for sequencing nucleic acids in which visualization of the bases in the sequence relies on the use of radioactive materials,… »
A radioactive iodide salt that distributes mainly within the extracellular body fluid and selectively concentrates in certain organ tissues, including the thyroid… »
The substance which is radioactive. »
An implementation of a compartmental model to quantify the time behavior of a tracer's uptake in a tissue. »
The quality of emitting or the emission of corpuscular or electromagnetic radiations consequent to nuclear disintegration, a natural property of all chemical… »
A unit used to express the number of nuclear transformations in a time unit in a unit volume of radionuclide. »
The process of measuring a radioactivity sample in the scanner and a counter. The result is having a consistent measure of radioactivity… »
A type of blood test used to test for allergies. »
The age of plant or animal remains determined by measuring the remaining activity of the 14C atoms in the sample: A =… »
The use of the regular known rates of radiocarbon decay to determine the exact ages of carbon-based life. »
The science concerned with the effects of radioactivity on health. »
Tipo de radioterapia externa en la que se usa un equipo especial para poner en posición al paciente y dirigir una sola… »
Tipo de radioterapia externa en la que se usa un equipo especial para poner en posición al paciente y dirigir una sola… »
Tipo de radioterapia externa en la que se usa un equipo especial para poner en posición al paciente y dirigir una sola… »
Compounds comprised of a radioactive agent linked to a pharmacological substance to be used to prevent, diagnose, or treat various diseases, including… »
The transparency of a material to the passage of X-rays and other forms of radiation. »
Tipo de radioterapia que se usa para tratar el cáncer de hígado avanzado o que ha reaparecido. Se inyectan unas cuentas pequeñas… »
A type of radiation therapy used to treat liver cancer that is advanced or has come back. Tiny beads that hold the… »
Medicamento que contiene una sustancia radiactiva y se utiliza para el diagnóstico y el tratamiento de enfermedades, incluso del cáncer. También… »
A procedure that uses radio waves to heat and destroy abnormal cells. The radio waves travel through electrodes (small devices that carry… »
Issue associated with the degradation of the reception of a wanted signal caused by RF disturbance. »
A type of low-energy radiation. The most common sources of radiofrequency radiation are wireless and cellular telephones, radios, televisions, radar, satellites, microwave… »
Radiografía de los órganos interiores del abdomen. Un rayo X es un tipo de haz de energía que puede atravesar el cuerpo… »
Radiografía de las estructuras ubicadas en el interior del tórax. Un rayo X es un tipo de radiación de alta energía que… »
An image produced on a radiosensitive surface by x-ray radiation that has penetrated and passed through a structure. »
A radiographic procedure using the emission of x-rays to form an image of the structure penetrated by the radiation. »
A method that uses radioactive substances to make pictures of areas inside the body. The radioactive substance is injected into the body,… »
Método para el que se utilizan sustancias radiactivas para crear imágenes de áreas del interior del cuerpo. Se inyecta la sustancia radiactiva… »
A branch of chemistry concerned with radioimmunoconjugates. »
Radioimmunoassay (RIA) is an immunological technique, which quantitatively determines antigen and antibody concentrations, using a radioactively labeled substance (radioligand), either directly or… »
A radioactive substance that carries radiation directly to cancer cells. A radioimmunoconjugate is made by attaching a radioactive molecule to an… »
The use of radiolabeled monoclonal antibodies to help diagnose diseases, including cancer. The radiolabeled monoclonal antibody locates and binds to substances in… »
A procedure that uses radioactive substances to locate tumors so that they can be removed by surgery. »
The use of radiolabeled monoclonal antibodies to treat diseases, including cancer. The radiolabeled monoclonal antibody locates and binds to substances in the… »
A type of radiation therapy in which a radioactive substance is linked to a monoclonal antibody and injected into the body. The… »
Sustancia radioactiva que irradia directamente las células cancerosas. Los radioinmunoconjugados se forman al unir una molécula radiactiva a una sustancia inmunitaria, como… »
Uso de anticuerpos monoclonales radiomarcados para ayudar a diagnosticar enfermedades, incluso el cáncer. Los anticuerpos monoclonales radiomarcados localizan sustancias en el cuerpo,… »
Uso de anticuerpos monoclonales radiomarcados para ayudar a diagnosticar enfermedades, incluso el cáncer. Los anticuerpos monoclonales radiomarcados localizan sustancias en el cuerpo,… »
Tipo de radioterapia para la que se une una sustancia radiactiva a un anticuerpo monoclonal y se inyecta en el cuerpo. El… »
An unstable form of a chemical element that releases radiation as it breaks down and becomes more stable. Radioisotopes may occur in… »
The formation of radioactive compounds by the use of a cyclotron or nuclear reactor. »
Treatment of a disease by means of exposure of the target or the whole body to radioisotopes. »
A laboratory procedure that results in the incorporation of a radioactive isotope into a molecule of interest. »
Forma inestable de un elemento que libera radiación a medida que se descompone y se vuelve más estable. Los radioisótopos se pueden… »
Sustancia radiactiva que se inyecta en una vena y se deposita en las células óseas y en las células tumorales que se… »
Any compound that has been joined with a radioactive substance. »
A radioimmunoconjugate comprised of a humanized monoclonal antibody with antitumor activity. The monoclonal antibody CC49 is developed from the murine monoclonal antibody… »
Radiolabeling Shared Resource provides Cancer Center investigators with support in preparation of radiolabeled reagents (proteins, peptides, hormones, oligonucleotides, antibodies, etc.) for in… »
Utilización de radiación (por ejemplo, rayos X) u otras tecnologías de imaginología (por ejemplo, el ultrasonido y la imaginología por resonancia magnética)… »
A test that uses radiation or other imaging procedures to find signs of cancer or other abnormalities. »
Results that have been obtained through x-ray imaging. »
Health concerns associated with the effects of radiation on the environment and on public and personal health. »
A person trained and qualified to perform radiographic procedures by the application of ionizing radiation to produce images on film and on… »
A doctor who specializes in creating and interpreting pictures of areas inside the body. The pictures are produced with x-rays, sound waves,… »
The first in a series of radiologists that are performing an assessment. »
The second in a series of radiologists that are performing an assessment. »
Médico que se especializa en crear e interpretar imágenes de área internas del cuerpo. Las imágenes se producen por medio de rayos… »
The use of radiation (such as x-rays) or other imaging technologies (such as ultrasound and magnetic resonance imaging) to diagnose or treat… »
A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease of… »
A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease of… »
A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease of… »
A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease of… »
The quality of being almost completely transparent to X-rays or other forms of radiation; the amount of radiation that is permitted to… »
Cualquier compuesto que se ha unido a una sustancia radiactiva. »
The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by scintillation counting. »
An unstable form of a chemical element that releases radiation as it breaks down and becomes more stable. Radionuclides may occur in… »
A device that produces a useful radionuclide from a parent substance contained within. As the parent decays a daughter, the useful radionuclide,… »
An imaging technique that uses a small dose of a radioactive chemical (isotope) called a tracer that can detect sites of cancer… »
The amount of radioactive material remaining in a syringe after administration, measured as counts per minute. »
A procedure that produces pictures (scans) of structures inside the body, including areas where there are cancer cells. Radionuclide scanning is used… »
The radioactivity per unit mass of a stated element or compound. »
The total amount of radioactive material present in a syringe prior to administration, measured as counts per minute. »
The total amount of radioisotope administered during a diagnostic or therapeutic event. »
A multi-gated acquisition (MUGA) scan and a form of radionuclide imaging that provides a comprehensive look at blood flow and the function… »
Forma inestable de un elemento que libera radiación a medida que se descompone y se vuelve más estable. Los radionúclidos se pueden… »
A drug that contains a radioactive substance and is used to diagnose or treat disease, including cancer. Also called radioactive drug. … »
An agent that contains a radioactive isotope and is used for diagnostic or therapeutic purposes. »
The amount of radiopharmaceutical given to a subject. »
Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for… »
Utilización de un medicamento que hace que las células tumorales se vuelvan más sensibles a la radioterapia. »
Cualquier sustancia que hace que las células tumorales se vuelvan más sensibles a la radioterapia. Algunos radiosensibilizadores están en estudio para el… »
The use of a drug that makes tumor cells more sensitive to radiation therapy. »
Any substance that makes tumor cells easier to kill with radiation therapy. Some radiosensitizers are being studied in the treatment of… »
A dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and… »
Any substance that makes tumor cells easier to kill with radiation therapy. Some radiosensitizing agents are being studied in the treatment of… »
A type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of… »
Profesional de la salud que administra la radioterapia. »
Uso de radiación de alta energía proveniente de rayos X, rayos gamma, neutrones, protones y otras fuentes para destruir células cancerosas y… »
Tratamiento de radiación en el que la dosis total de radiación se administra en un período de tiempo más corto (en menos… »
Tipo de radioterapia para la que se usan rayos X o rayos gamma que produce una máquina especial que se llama acelerador… »
Tipo de radioterapia que usa corrientes de protones (partículas diminutas con carga positiva) para destruir células tumorales. Este tipo de tratamiento puede… »
Tipo de radioterapia en el que se coloca un material radiactivo sellado en agujas, semillas, cables o catéteres directamente en el tumor… »
Tipo de radioterapia externa en la que se usa una máquina especial para producir partículas invisibles de alta energía (protones o iones… »
Tipo de radioterapia que se usa para tratar los tumores del ojo. Se coloca a un costado del ojo un trozo delgado… »
Procedimiento para el que se usa una computadora para crear una imagen tridimensional del tumor. Esto permite que los médicos administren la… »
Tipo de radioterapia externa para la que se usa un equipo especial para colocar en posición al paciente y administrar con precisión… »
Tipo de radioterapia que usa una máquina para enfocar rayos de alta energía hacia el cáncer desde el exterior del cuerpo. También… »
Tipo de radioterapia tridimensional que usa imágenes creadas por una computadora para mostrar el tamaño y la forma de un tumor. Se… »
Tipo de radioterapia externa en la que se usa un equipo especial para poner en posición al paciente y administrarle la radiación… »
Tipo de radioterapia externa en la que se usa un equipo especial para poner en posición al paciente y administrarle la radiación… »
Tipo de radioterapia externa en la que se usa un equipo especial para poner en posición al paciente y administrarle la radiación… »
Tipo de radioterapia que usa una máquina para enfocar rayos de alta energía hacia el cáncer desde el exterior del cuerpo. También… »
Tratamiento de radiación en el que la dosis total de radiación se divide en dosis pequeñas y los tratamientos se administran más… »
Procedimiento para el que se usa una computadora para crear una imagen de un tumor y así guiar el haz de radiación… »
Tratamiento de radiación en el que se divide la dosis total de radiación en dosis pequeñas y los tratamientos se administran más… »
Tratamiento de radiación en el que la dosis total de radiación se divide en dosis grandes y el tratamiento se administra menos… »
Tipo de radioterapia en el que se coloca un material radiactivo sellado en agujas, semillas, cables o catéteres directamente en el tumor… »
Radioterapia que se administra al inyectar una sustancia radiactiva en el torrente sanguíneo o una cavidad del cuerpo, o al ingerirla. Esta… »
Tipo de radioterapia interna en la que se coloca un material radiactivo sellado en agujas, semillas cables o catéteres directamente en un… »
Tipo de radioterapia interna en la que se coloca un material radiactivo sellado en agujas, cables o catéteres directamente en una cavidad… »
Tratamiento de radiación dirigida directamente al tumor durante la cirugía. También se llama RIO. »
Tratamiento en el que se introduce un líquido radiactivo directamente en el abdomen, por un tubo delgado. »
Tipo de tratamiento de radiación interna en la que la fuente radiactiva se extrae entre tratamientos. También se llama braquiterapia remota y… »
Tratamiento de radiación en el que se divide la dosis total de radiación en dosis pequeñas y los tratamientos se administran más… »
Tipo de radioterapia en la que se usan electrones dirigidos a toda la superficie del cuerpo. Este tipo de radiación va a… »
Tipo de radioterapia externa que se usa para tratar a los pacientes que tienen cáncer en el cerebro. A menudo… »
Procedimiento para el que se usa una computadora para crear una imagen tridimensional del tumor. Esto permite que los médicos administren la… »
Tipo de radioterapia en la que se usan electrones dirigidos a toda la superficie del cuerpo. Este tipo de radiación va a… »
Forma de radiación que se usa para el tratamiento del cáncer. »
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation… »
The medical specialty concerned with the use of electromagnetic or particulate radiation in the treatment of disease. »
A tissue-equivalent material placed in contact with the skin to increase the surface dose and/or compensate for missing tissue. A bolus can… »
[Therapeutic implications] Research in radiotherapy using ionizing and non-ionizing radiation and those areas in radiobiology and radiation physics that relate to radiation… »
A drug used to treat prostate cancer that has spread to the bone and has not gotten better with other treatment. It… »
A radiopharmaceutical composed of the dichloride salt of the alpha-emitting isotope radium Ra 223, with antineoplastic activity. Like calcium, radium targets bone… »
A drug used to treat prostate cancer that has spread to the bone and has not gotten better with other treatment. It… »
A short-lived, alpha-emitting isotope found in ground water and soils, Radium-224 has been used in biomedical treatments. Radium-224 in drinking water is… »
A straight line from the center to the perimeter of a circle or from the center to the surface of a… »
The long bone of the forearm that extends from the lateral aspect of the elbow to the thumb-side of the wrist. … »
A traditional Chinese medicine comprising of Radix Angelicae Sinensis (RAS) and Radix Astragali (RA), with potential anti-inflammatory, immunostimulatory, neuroprotective, anti-hepatotoxic and antineoplastic… »
A radioactive gas that is released by uranium, a substance found in soil and rock. Breathing in too much radon can damage… »
Gas radiactivo que emana del uranio, una sustancia que se encuentra en el suelo y la roca. Inhalar demasiado radón puede dañar… »
An orally available, hydrochloride salt form of radotinib, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor… »
Refractory anemia with excess blasts associated with significant reticulin fibrosis of the bone marrow. »
A myelodysplastic syndrome defined by 5-9% blasts in the bone marrow, and <5% blasts in the blood. Approximately 25% of cases… »
A myelodysplastic syndrome defined by 10-19% blasts in the bone marrow or 5-19% blasts in the blood and <10% blasts in the… »
Any substance that inhibits Raf Kinase, an enzyme active in signal transduction in the Ras pathway. Inhibition of Raf kinase may result… »
An orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein… »
An orally active, small molecule with potential antineoplastic activity. XL281 specifically inhibits RAF kinases, located downstream from RAS in the RAS/RAF/MEK/ERK kinase… »
RAF proto-oncogene serine/threonine-protein kinase (648 aa, ~73 kDa) is encoded by the human RAF1 gene. This protein plays a role in cell… »
A protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity. Raf/MEK dual kinase Inhibitor… »
This gene is involved in cell growth, proliferation, differentiation and migration. It also plays a role in apoptosis. »
Human RAF1 wild-type allele is located within 3p25 and is approximately 81 kb in length. This allele, which encodes RAF proto-oncogene serine/threonine-protein… »
Oligosaccharide comprised of a galactose molecule and sucrose bound together with an alpha 1-6 linkage. »
A substance that is used to improve the health of the digestive system and bones and is being studied in the prevention… »
Sustancia que se usa para mejorar la salud del aparato digestivo y los huesos, y que está en estudio para la prevención… »
Human RAG1 wild-type allele is located in the vicinity of 11p13 and is approximately 12 kb in length. This allele, which encodes… »
Human RAG2 wild-type allele is located in the vicinity of 11p13 and is approximately 6 kb in length. This allele, which encodes… »
A dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist with hypoglycemic activity. Ragaglitazar reduces blood pressure (BP) and improves endothelial function… »
A genus of facultatively anaerobic, Gram negative, rod shaped bacterium in the phylum Fusobacteria and the family Enterobacteriaceae. »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria in the phylum Fusobacteria. This species is weakly positive for phenylalanine… »
A staging system for Chronic Lymphocytic Leukemia. Stage 0: absolute lymphocytosis (>15,000 per cubic millimeter) without adenopathy, hepatosplenomegaly, anemia, or thrombocytopenia;… »
Human RAI1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 130 kb in length. This allele, which encodes… »
A bar designed for support, attachment, guidance, or protection from falling. »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
Raíz de cualquier planta del grupo de hierbas llamadas Angélica. Se ha usado en algunas culturas para tratar ciertos problemas médicos, incluso… »
Raíz de una planta llamada Polygala senega. Se ha usado en algunas culturas para tratar ciertos problemas médicos, incluso problemas del aparato… »
Hierba perenne del este de América del Norte. Una sustancia obtenida de la raíz de la planta se ha usado en algunas… »
Encoded by human RALGDS Gene, 914-aa 101-kDa RAL Guanine Nucleotide Dissociation Stimulator is a guanine nucleotide exchange factor containing an N-terminal RAS-GEF… »
Encoded by human RALA Gene (RAS GTPase Family), 206-aa 24-kDa GTP-binding RAS-like RALA Protein interacts with RALBP1 via its effector domain and… »
Human RALA wild-type allele is located within 7p15-p13 and is approximately 85 kb in length. This allele, which encodes Ras-related protein Ral-A,… »
RalA-binding protein 1 (655 aa, ~76 kDa) is encoded by the human RALBP1 gene. This protein is involved in the regulation of… »
RAL proteins share homology and some properties with the RAS proteins. RALB is a GTP-binding protein. (from OMIM 179551 and… »
Human RALB wild-type allele is located within 2cen-q13 and is approximately 42 kb in length. This allele, which encodes Ras-related protein Ral-B,… »
This gene is involved in the regulation of small GTPase activity. »
Human RALBP1 wild-type allele is located in the vicinity of 18p11.3 and is approximately 63 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and cytoskeletal remodeling. It is also involved in regulation of cell growth. »
Human RALGDS wild type allele is located in the vicinity of 9q34.3 and is approximately 52 kb in length. This allele, which… »
The active ingredient in a drug used to reduce the risk of invasive breast cancer in postmenopausal women who are at high… »
A drug used to reduce the risk of invasive breast cancer in postmenopausal women who are at high risk of the disease… »
Ingrediente activo de un medicamento que se usa para reducir el riesgo de cáncer de mama invasor en las mujeres posmenopáusicas que… »
A genus of Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria and the family Burkholderiaceae. »
A species of xaerobic, gram-negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is urease, catalase and oxidase positive, does… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is non-fermentative and is not susceptible to… »
A small molecule with activity against human immunodeficiency virus (HIV). Raltegravir is an integrase inhibitor that blocks the integration of the viral… »
The orally bioavailable potassium salt of a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir… »
An anticancer drug that stops tumor cells from growing by blocking the ability of cells to make DNA. It belongs to the… »
Medicamento contra el cáncer que impide que las células tumorales crezcan porque bloquea la capacidad de las células de producir ADN. Es… »
Emission of electromagnetic energy with a shorter frequency (longer wavelength) than that of the incident monochromatic light. Arises from the low… »
A synthetic melatonin analogue with hypnotic and circadian rhythm-modulating activities. Ramelteon binds to and activates melatonin receptors 1 and 2 in the… »
A prodrug and nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de-esterification into its… »
A non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Ramiprilat inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin… »
The hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity. Upon administration, ramosetron selectively binds to and… »
A traditional unit of length equal to 100 feet. »
A substance being studied in the treatment of breast cancer that has come back. It binds to receptors for a protein called… »
Sustancia en estudio para el tratamiento de cáncer de mama que volvió. Se une a los receptores de una proteína que se… »
An artery that arises from the left main coronary artery and is positioned between the left anterior descending coronary artery and the… »
Medición del número de neutrófilos en la sangre. Los neutrófilos son un tipo de glóbulo blanco. Ayudan a combatir infecciones. Se puede… »
Ran is a member of the Ras family of small GTPases. Ran is an important component of many crucial nucleocytoplasmic transport… »
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1… »
Ran-binding protein 17 (1088 aa, ~124 kDa) is encoded by the human RANBP17 gene. This protein may play a role in the… »
This gene may play a role in nuclear transport. »
Human RANBP17 wild-type allele is located in the vicinity of 5q34 and is approximately 438 kb in length. This allele, which encodes… »
A data storage device for which the order of access to different locations does not affect the speed of access. RAM can… »
Generation of peptide libraries by random incorporation of all 20 amino acids. »
A procedure in which a fine needle is inserted around the area of the areola to aspirate cells from the breast parenchyma… »
A method of selecting a sample from a population in such a way that every sample that could be selected has an… »
A number (or vector) used to generate random numbers in a system. »
When referring to an experiment or clinical trial, the process by which animal or human subjects are assigned by chance to separate… »
An item/element of a randomization book that can be used to assign a subject to a planned arm or portion of an… »
Specifies whether the position is filled by a subject assignment. »
An integer specifying the value of a numerical sequence for a Stratum Group that should be used to assign a subject to… »
An indicator that can be set or unset in order to signal whether a study is randomized. »
The number of planned subjects to be exposed to investigational therapy, independent of dose or other factors, divided by the total number… »
The quotient of quantities of trial subjects within treatment or control groups using an element of chance to determine the assignments, in… »
The relative proportion of subjects to be randomized. »
To make random in arrangement, especially in order to control the variables in an experiment. (dictionary.com) »
A study in which the participants are assigned by chance to separate groups that compare different treatments; neither the researchers nor the… »
A study in which the participants are assigned by chance to separate groups to evaluate treatments. The study also includes a… »
Sustancia en estudio para el tratamiento de la osteoporosis en las mujeres posmenopáusicas. El ranelato de estroncio ayuda a que crezca tejido… »
This gene plays a role in signal transduction and nucleocytoplasmic transport. »
Human RANGAP1 wild-type allele is located in the vicinity of 22q13 and is approximately 57 kb in length. This allele, which encodes… »
The difference between the lowest and highest numerical values; the limits or scale of variation. »
A measure of joint flexibility, range of motion is the normal range of movement for a joint, consisting of flexion, how far… »
A second-generation, recombinant humanized IgG1 kappa monoclonal antibody fragment directed against human vascular endothelial growth factor (VEGF) alpha. Ranibizumab binds to VEGF… »
A chloroethylnitrosourea derivative that inhibits proliferation and growth of tumor cells by alkylation and cross-linkage of DNA strands of tumor cells. … »
A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action… »
A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action… »
A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action… »
An orally available, piperazine derivative with anti-anginal and potential antineoplastic activities. Ranolazine's mechanism of action for its anti-ischemic effects has yet to… »
A substance being studied in the treatment of cancer. It is a type of ribonuclease enzyme. Also called Onconase. »
Sustancia en estudio para el tratamiento de cáncer. Es un tipo de enzima de ribonucleasa. También se llama Onconase. »
A genus of aerobic, Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria and the family Enterobacteriaceae. »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is ornithine decarboxylase positive, able to grow… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species can deaminate tryptophan, is able to grow… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is ornithine decarboxylase negative, cannot deaminate tryptophan,… »
Ubiquitously expressed by human GRF2 Gene (as at least 2 alternative isoforms), Guanine Nucleotide-Releasing Factor-2 is an adaptor-type Ras-GEF/SH2-domain protein involved in… »
Rap1 GTPase-GDP dissociation stimulator 1 (607 aa, ~66 kDa) is encoded by the human RAP1GDS1 gene. This protein is involved in the… »
This gene plays a role in signal transduction and cell adhesion. »
Human RAP1A wild-type allele is located in the vicinity of 1p13.3 and is approximately 174 kb in length. This allele, which encodes… »
This gene is involved in guanine nucleotide exchange. »
Human RAP1GDS1 wild-type allele is located within 4q23-q25 and is approximately 182 kb in length. This allele, which encodes Rap1 GTPase-GDP dissociation… »
Medicamento que se usa para impedir que el cuerpo rechace los trasplantes de órganos y médula ósea. La rapamicina impide que… »
A drug used to keep the body from rejecting organ and bone marrow transplants. Rapamune blocks certain white blood cells that can… »
Medicamento que se usa impedir que el cuerpo rechace los trasplantes de órganos y médula ósea. Rapamune impide que ciertos glóbulos… »
A drug used to keep the body from rejecting organ and bone marrow transplants. Rapamycin blocks certain white blood cells that can… »
Rapamycin-insensitive companion of mTOR (1708 aa, ~192 kDa) is encoded by the human RICTOR gene. This protein is involved in regulation of… »
A population of T lymphocytes polarized by rapamycin with potential immunomodulating activity. The autologous T cells collected from the patient were co-stimulated… »
Tipo de tabaco sin humo que se hace con hojas de tabaco finamente molido o triturado. Puede tener diferentes aromas y sabores,… »
This gene plays a role in signal transduction as well as protein binding and trafficking. »
Human RAPGEF1 wild type allele is located in the vicinity of 9q34.3 and is approximately 163 kb in length. This allele, which… »
This gene is involved in receptor signaling and neurogenesis. »
Human RAPGEFL1 wild-type allele is located within 17q21.1-q21.2 and is approximately 17 kb in length. This allele, which encodes Rap guanine nucleotide… »
A group of nuclei that are located in the midline of the brainstem and release serotonin. »
RAID is a new program designed to facilitate translation to the clinic of novel, scientifically meritorious therapeutic interventions originating in the academic… »
An immunoassay that can quickly detect the presence of specific antigens in a sample and return results during a patient visit. … »
One of the five stages of sleep. During rapid eye movement sleep, the eyes move rapidly while closed and dreams occur. Rapid… »
A procedure in which drugs that block the production of male hormones are alternated with male hormones and/or drugs that promote the… »
The determination of the antibodies produced by cellular damage caused by Treponema pallidum present in a sample. »
Screening techniques for alpha thalassemia that use melting curve analysis of PCR products generated from the alpha globin alleles. »
A substance that acts quickly to treat moderate to severe pain. Opioids are like opiates, such as morphine and codeine, but are… »
A monoclonal antibody used to treat psoriasis (a chronic skin disease). It is also being studied in the treatment of graft-versus-host disease… »
Anticuerpo monoclonal que se usa para tratar la psoriasis (una enfermedad crónica de la piel). Asimismo, está en estudio para el tratamiento… »
Afección por la que los huesos de los niños se vuelven blandos y se deforman porque no tienen suficicente calcio y… »
Afección por la que los huesos de los niños se vuelven blandos y se deforman porque no tienen suficicente calcio y… »
Afección infantil en la que los huesos se vuelven blandos y deformes debido a la falta de calcio y fósforo. Por lo… »
Afección por la que los huesos de los niños se vuelven blandos y se deforman porque no tienen suficicente calcio y… »
Afección por la que los huesos de los niños se vuelven blandos y se deforman porque no tienen suficicente calcio y… »
Once retinoids are bound by the RAR/RXR heterodimer they became transcriptional activated. As a consequence they are degraded by the proteasome. Phosphorylation… »
Human RARA wild-type allele is located within 17q21 and is approximately 48 kb in length. This allele, which encodes retinoic acid receptor… »
A fusion gene that results from a chromosomal translocation t(15;17)(q22;q21) which fuses the first 2 exons of the RARA gene with the… »
A fusion gene that results from a chromosomal translocation t(11;17)(q23;q21) which fuses the exon 3 of the RARA gene to the 3'… »
A fusion protein encoded by the RARA/ZBTB16 fusion gene. This protein is comprised of the N-terminal transcriptional activation domain of the retinoic… »
This gene is involved in the regulation of embryonic morphogenesis and related processes. »
Human RARB wild-type allele is located within 3p24 and is approximately 170 kb in length. This allele, which encodes retinoic acid receptor… »
A broad classification for uncommon disorders in which the development of neoplasms occur in association with a characteristic set of signs or… »
A rare disease is one that affects fewer than 200,000 people in the United States. There are nearly 7,000 rare diseases. More… »
A non-malignant disease that affects fewer than 200,000 people in the United States. »
Human RARG wild-type allele is located within 12q13 and is approximately 22 kb in length. This allele, which encodes retinoic acid receptor… »
This gene plays a putative role in the inhibition of cell proliferation. »
Human RARRES3 wild-type allele is located in the vicinity of 11q23 and is approximately 9 kb in length. This allele, which encodes… »
Ras association domain family 1 protein (344 aa, ~39 kDa) is encoded by the RASSF1 gene. This protein is inextricably involved in… »
RAS association domain-containing protein 5 (418 aa, ~47 kDa) is encoded by the human RASSF5 gene. This protein plays a role in… »
A family of genes that encode structurally similar small GTPases involved in a variety of signal transduction pathways. Mutation of genes in… »
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras… »
A family of genes that may cause cancer when they are mutated (changed). They make proteins that are involved in cell signaling… »
Ras GTPase-activating protein 1 (1047 aa, ~116 kDa) is encoded by the human RASA1 gene. This protein is involved in the regulation… »
RAS guanyl-releasing protein 1 (797 aa, ~90 kDa) is encoded by the human RASGRP1 gene. This protein plays a role in the… »
Encoded by human oncogene ARHH Gene, the 191-amino acid 21 kD hemopoietic cell RHOH/TTF Protein contains residues associated with binding and hydrolysis… »
RHO A GTP-binding protein is involved in regulating signal transduction pathways that control assembly of focal adhesions and actin stress fibers. … »
Encoded by human ARHI Gene, the 229-amino acid 26 kD RHO-Related GTP-Binding Protein RHOI (RHO Family) appears to be a tumor suppressor… »
An agent designed to inhibit the signal transduction process by interfering with the action of the ras protein. »
A short piece of the ras protein, which is made by the ras gene. The ras gene has been found to cause… »
A synthetic form of the ras peptide containing a point mutation at position 12 (glycine to aspartic acid) with potential antineoplastic… »
A cancer vaccine containing a RAS oncogene-encoded peptide with potential antineoplastic activity. RAS peptide cancer vaccine may stimulate a RAS peptide-specific… »
A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to cysteine) with potential antineoplastic activity. … »
A synthetic form of the Ras peptide containing a point mutation at position 12 (glycine to valine) with potential antineoplastic activity. … »
The protein is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that… »
Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form. RASGRF2 is able to… »
Ras activates many signaling cascades. Here we illustrate some of the well-characterized cascades in a generic compilation of effector molecules. … »
Small cellular monomeric proteins with GTPase activity, RAS Superfamily Proteins are involved in signal transduction in normal cellular growth, differentiation, and… »
Expressed as multiple alternative transcript variants by human RSU1 Gene, RAS Suppressor Protein 1 is likely involved in the RAS signal transduction… »
NK (natural killer) cells are lymphocytes distinct from B and T cells that induce perforin-mediated lysis of tumor cells and virus-infected… »
Ras-interacting protein 1 (963 aa, ~103 kDa) is encoded by the human RASIP1 gene. This protein is involved in signal transduction. … »
The 203-aa 23-kDa RAS-Like Protein RRP22 is expressed in brain by human RRP22 Gene (Small GTPase Family). »
Ras-related C3 botulinum toxin substrate 1 (192 aa, ~21 kDa) is encoded by the human RAC1 gene. This protein is involved in… »
Ras-related C3 botulinum toxin substrate 3 (192 aa, ~21 kDa) is encoded by the human RAC3 gene. This protein is involved in… »
Encoded by human RAGA Gene, RAS-Related GTP-Binding Protein RAGA is a RAS-related GTP-binding protein lacking GTPase activity that interacts with adenovirus E3… »
Encoded by IL9-induced, but not IL2 or IL4, human MRAS Gene (Ras GTPase Family) in brain and heart only, 208-aa 24-kDa RAS-Related… »
Ras-related protein R-Ras (218 aa, ~23 kDa) is encoded by the human RRAS gene. This protein is involved in both the positive… »
Encoded by human RRAS2 Gene (RAS GTPase Family), ubiquitous 204-aa 23-kDa RAS-Related Protein R-RAS2 is a plasma membrane-associated GTP-binding GTPase that may… »
Ras-related protein Rab-23 (237 aa, ~27 kDa) is encoded by the human RAB23 gene. This protein is involved in both intracellular signaling… »
Ras-related protein Rab-40B (278 aa, ~31 kDa) is encoded by the human RAB40B gene. This protein may be involved in the regulation… »
Ras-related protein Rab-5C (216 aa, ~23 kDa) is encoded by the human RAB5C gene. This protein plays a role in GTPase… »
Encoded by human RAP1A Gene (RAS GTPase Family), 184-aa 21-kDa (precursor) membrane-bound RAS-Related Protein RAP1A is activated by guanine nucleotide-exchange factors EPAC… »
This gene is involved in the modulation of GTPase activity. »
Human RASA1 wild-type allele is located in the vicinity of 5q13.3 and is approximately 124 kb in length. This allele, which encodes… »
A drug used to treat high blood levels of uric acid in patients with leukemia, lymphoma, and other types of cancer who… »
Medicamento que se usa para tratar concentraciones altas de ácido úrico en pacientes con leucemia, linfoma y otros tipos de cáncer que… »
This gene is involved in signal transduction and cell organization/biogenesis. »
Human RASD1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 2 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and putatively plays a role in long-term memory. »
Human RASGRF1 wild type allele is located in the vicinity of 15q24 and is approximately 129 kb in length. This allele, which… »
This gene plays a role in signal transduction and receptor signaling. »
Human RASGRF2 wild type allele is located in the vicinity of 5q13 and is approximately 269 kb in length. This allele, which… »
This gene plays a role in guanine nucleotide exchange. »
Human RASGRP1 wild-type allele is located in the vicinity of 15q14 and is approximately 77 kb in length. This allele, which encodes… »
An assay finding indicating that the ratio of the gene pair RASGRP1/APTX that is expressed in leukemic cells is equal to or… »
A rash is an area of irritated or swollen skin. Many rashes are itchy, red, painful, and irritated. Some rashes can also… »
This gene is involved in signal transduction. »
Human RASIP1 wild-type allele is located in the vicinity of 19q13.33 and is approximately 20 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction. »
Human RASL10A wild-type allele is located in the vicinity of 22q12.2 and is approximately 22 kb in length. This allele, which encodes… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
This gene plays a role in the maintenance of genomic integrity and possibly tumor suppression. »
Human RASSF1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 11 kb in length. This allele, which encodes… »
This gene plays a role in both lymphocyte adhesion and suppression of cell growth. »
Human RASSF5 wild-type allele is located in the vicinity of 1q32.1 and is approximately 82 kb in length. This allele, which encodes… »
A synthetic vaccine used for cancer immunotherapy also known as Ras(cis 12)-Vaccinia Vaccine, RASVAC-C is based on a mutant peptide epitope of… »
A synthetic vaccine used for cancer immunotherapy also known as Ras(val 12)-Vaccinia Vaccine, RASVAC-C is based on a mutant peptide epitope of… »
Body tissues, cavities, fluids, organs, or systems pertaining specifically to rat anatomy. »
A benign bone neoplasm arising from the remnants of the fetal notochord. »
A benign neoplasm of the ovary, originating from granulosa cells. »
A collaborative effort between research institutions involved in rat genetic and genomic research for the establishment of a database to collect, consolidate,… »
A benign epithelial neoplasm arising from the pars distalis of the anterior pituitary gland. »
A malignant epithelial neoplasm arising from the pars distalis of the anterior pituitary gland. »
A benign epithelial neoplasm arising from the pars intermedia of the anterior pituitary gland. »
A malignant epithelial neoplasm arising from the pars intermedia of the anterior pituitary gland. »
Disorders of the rat that are characterized by cell proliferation, organized by body location. »
Proteins found in any species or strain of rat. »
A benign tubular adenoma with Sertoli cell differentiation. »
Breeds of rats utilized for biological research. »
Modification of a rat by transgenic techniques. »
A syndrome characterized by recurring fever, rash, and arthralgias occurring days to weeks after a rat bite. The causative agents are either… »
Parameter appearing in models to describe a unidirectional transfer rate out of a compartment. It is the (amount transferred per unit time)/(amount… »
A sensor for a pacemaker designed to alter the rate of heart stimulation based on the activity level of the subject. … »
The speed at which an action is performed. »
A tubular outgrowth of ectoderm from the stomodeum of the embryo; it grows dorsad toward the infundibular process of the diencephalon, around… »
Rathke's pouch cysts are rarely symptomatic in the first two decades of life though they may produce symptoms in the third and… »
A racemic mixture of liothyronine, a synthetic version of triiodothyronine (T3), the primary active thyroid hormone. Like endogenous T3, DL-liothyronine exerts its… »
A data type comprised of a numerator quantity divided by a denominator quantity. »
A scale that uses ordered numbers with a constant difference and which has a natural zero. »
A number that can be expressed as a fraction p/q where p and q are integers and q does not equal… »
Tipo de ratón de laboratorio que es calvo, carece de una glándula del timo normal y tiene un sistema inmunitario defectuoso debido… »
Uso de cepas especiales de ratones para estudiar una enfermedad o afección humana, y la manera de prevenirla y tratarla. »
Ratones a los que se le puso ADN de otro origen en su ADN. El ADN exógeno se coloca en el núcleo… »
An eastern North American perennial herb. A substance obtained from the root of the plant has been used in some cultures to… »
An herb native to islands in the South Pacific. Substances taken from the root have been used in some cultures to relieve… »
Hierba nativa de las islas del sur del Pacífico. Las sustancias tomadas de la raíz se han usado en algunas culturas para… »
A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory… »
Anticuerpo monoclonal en estudio para el tratamiento de algunos tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
Sustancia en estudio para el tratamiento de infecciones causadas por hongos. Pertenece al tipo de medicamentos llamados antifúngicos o antimicóticos. »
A substance that is being studied in the treatment of infections caused by fungi. It belongs to the family of drugs called… »
An idiopathic vascular disorder characterized by ischemic attacks in the fingers, toes, ears, or nose, associated with pain and pallor. The attacks… »
A set of symptoms characteristic of peripheral vascular disease, namely caused by an inappropriate response of the peripheral arteries in reaction to… »
Tipo de radiación de alta energía que es distinta a un rayo X. »
Tipo de radiación que se usa para el diagnóstico y el tratamiento de cáncer y otras enfermedades. Cuando se aplican en dosis… »
Probablemente se sometió a un examen con rayos X en alguna parte del cuerpo. Los profesionales de la salud los usan para… »
An orally active, 1,2-benzisoxazole-containing, inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Razaxaban forms an isoxazole-ring opened, stable, benzamidine… »
The hydrochloride salt form of razaxaban, an orally active, 1,2-benzisoxazole-containing, inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Razaxaban… »
An orally bioavailable bis-dioxopiperazine and a derivative of the chelating agent ethylenediaminetetraacetic acid (EDTA) with antineoplastic, antiangiogenic, and antimetastatic activities. Razoxane specifically… »
A broad-spectrum carbapenem with activity against gram-positive bacteria, including methicillin-resistant S. aureus. »
This gene is involved in the regulation of cell differentiation, growth and proliferation. »
Human RB1 wild-type allele is located in the vicinity of 13q14.2 and is approximately 178 kb in length. This allele, which encodes… »
RB1-inducible coiled-coil protein 1 (1594 aa, ~183 kDa) is encoded by the human RB1CC1 gene. This protein is involved in the regulation… »
This gene is involved in the modulation of both the cell cycle and autophagy. »
Human RB1CC1 wild-type allele is located in the vicinity of 8q11 and is approximately 92 kb in length. This allele, which encodes… »
Encoded by human RBBP1L1 Gene, 803-amino acid 91 kD RBP1-Like Protein is similar to RBP1, containing a Tudor domain and an ARID… »
This gene is involved in the regulation of both transcription and cell proliferation. »
Human RBBP4 wild-type allele is located 1p35.1 and is approximately 35 kb in length. This allele, which encodes histone-binding protein RBBP4, plays… »
This gene is involved in cell cycle regulation. »
Human RBBP8 wild-type allele is located in the vicinity of 18q11.2 and is approximately 93 kb in length. This allele, which encodes… »
This gene is involved in the regulation of cellular proliferation and differentiation. »
Human RBBP9 wild-type allele is located in the vicinity of 20p11.2 and is approximately 11 kb in length. This allele, which encodes… »
A type of blood cell that is made in the bone marrow and found in the blood. RBCs contain a protein called… »
This gene plays a role in mRNA processing. »
Human RBFOX1 wild-type allele is located in the vicinity of 16p13.3 and is approximately 1694 kb in length. This allele, which encodes… »
Human RBL1 wild-type allele is located in the vicinity of 20q11.2 and is approximately 100 kb in length. This allele, which encodes… »
Human RBL2 wild-type allele is located in the vicinity of 16q12.2 and is approximately 57 kb in length. This allele, which encodes… »
This gene plays a role in RNA binding. »
Human RBM15 wild-type allele is located in the vicinity of 1p13 and is approximately 8 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(1;22)(p13;q13) which fuses the 5' portion of the RBM15 gene to the 3'… »
A fusion protein that is encoded by the RBM15/MKL1 fusion gene. This protein consists of most of the putative RNA-binding protein 15,… »
This gene is involved in both RNA splicing and mRNA stability. »
Human RBM38 wild-type allele is located in the vicinity of 20q13.31 and is approximately 18 kb in length. This allele, which encodes… »
Human RBM4 wild-type allele is located in the vicinity of 11q13 and is approximately 28 kb in length. This allele, which encodes… »
Human RBM5 wild-type allele is located in the vicinity of 3p21.3 and is approximately 30 kb in length. This allele, which encodes… »
Human RBM6 wild-type allele is located in the vicinity of 3p21.3 and is approximately 137 kb in length. This allele, which encodes… »
Widely expressed by human PLU-1 Gene (RBBP Family) at varying levels (highest in Sertoli cells), 1544-aa 176-kDa nuclear RBP2-Like Protein contains 3… »
Human RBX1 wild-type allele is located in the vicinity of 22q13.2 and is approximately 21 kb in length. This allele, which encodes… »
This gene is involved in modulation of protein phosphorylation. »
Human RCAN1 wild-type allele is located in the vicinity of 21q22.12 and is approximately 99 kb in length. This allele, which encodes… »
A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a constitutively active form of the AKT Gene. The… »
A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a human gene encoding the G12D mutant form of… »
Human RCN2 wild-type allele is located within 15q23 and is approximately 18 kb in length. This allele, which encodes reticulocalbin-2 protein, plays… »
Método de laboratorio usado para hacer muchas copias de una secuencia específica de ADN. También se llama reacción en cadena de la… »
Procedimiento de urgencia que se usa para reanudar los latidos cardíacos y la respiración de una persona después que uno… »
Roland Morris Disability Questionnaire (RDQ) My appetite is not very good because of my back pain. »
Roland Morris Disability Questionnaire (RDQ) I avoid heavy jobs around the house because of my back. »
Roland Morris Disability Questionnaire (RDQ) I change position frequently to try and get my back comfortable. »
Roland Morris Disability Questionnaire (RDQ) I find it difficult to get out of a chair because of my back. »
Roland Morris Disability Questionnaire (RDQ) I find it difficult to turn over in bed because of my back. »
Roland Morris Disability Questionnaire (RDQ) I get dressed more slowly then usual because of my back. »
Roland Morris Disability Questionnaire (RDQ) Because of my back pain, I get dressed with help from someone else. »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I try to get other people to do things for me. »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I go upstairs more slowly than usual. »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I have to hold on to something to get out of an easy… »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I lie down to rest more often. »
Roland Morris Disability Questionnaire (RDQ) Because of my back pain, I am more irritable and bad tempered with people than usual. … »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I am not doing any of the jobs that I usually do around… »
Roland Morris Disability Questionnaire (RDQ) I only stand for short periods of time because of my back. »
Roland Morris Disability Questionnaire (RDQ) I only walk short distances because of my back. »
Roland Morris Disability Questionnaire (RDQ) My back is painful almost all the time. »
Roland Morris Disability Questionnaire (RDQ) I sit down for most of the day because of my back. »
Roland Morris Disability Questionnaire (RDQ) I sleep less well because of my back. »
Roland Morris Disability Questionnaire (RDQ) I stay at home most of the time because of my back. »
Roland Morris Disability Questionnaire (RDQ) I stay in bed most of the time because of my back. »
Roland Morris Disability Questionnaire (RDQ) RDQ total derived score. »
Roland Morris Disability Questionnaire (RDQ) I have trouble putting on my socks (or stockings) because of the pain in my back. … »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I try not to bend or kneel down. »
Roland Morris Disability Questionnaire (RDQ) Because of my back, I use a handrail to get upstairs. »
Roland Morris Disability Questionnaire (RDQ) I walk more slowly than usual because of my back. »
A question associated with the RDQ questionnaire. »
Proteína que se encuentra en el interior de las células del tejido reproductor femenino, en algunos otros tipos de tejidos y en… »
Describe células que no tienen una proteína a la cual se unirá la hormona estrógeno. Las células cancerosas que son receptoras de… »
A surgical procedure to remove the remaining abnormal tissues from the body, not completely removed in an earlier attempt. »
Término que describe las células que tienen una proteína receptora que se une a la hormona estrógeno. Las células cancerosas que tienen… »
Proceso en el que una sustancia, tal como un tejido, se pierde al ser destruído y luego es absorbido por el… »
Método de laboratorio usado para hacer muchas copias de una secuencia específica de ADN. También se llama RCP. »
En las células vivas, las reacciones químicas que ayudan a mantener la vida y permiten que las células crezcan. »
An opposition to the flow of electric current resulting from inductance and capacitance (rather than resistance). »
Volver a activar o hacer que algo vuelva a funcionar. En el campo de la medicina, una infección o una enfermedad se… »
To make active again or make something work again. In medicine, an infection or a disease is described as reactivated when it… »
A non-neoplastic proliferation of C-cells in the thyroid gland caused by external stimuli such as hypercalcemia and chronic lymphocytic thyroiditis. »
A benign, epidermal skin lesion characterized by overexpression of collagen during wound healing. »
Depression precipitated by events in a person's life. »
A measurement of the reactive lymphocytes in a biological specimen. »
The determination of the number of reactive lymphocytes present in a blood sample. »
The determination of the ratio of reactive lymphocytes compared to all lymphocytes present in a sample. The measurement may be expressed as… »
A type of unstable molecule that contains oxygen and that easily reacts with other molecules in a cell. A build up… »
Sustancia que se usa en pruebas de laboratorio. Los reactivos se usan en una reacción química para detectar, medir, o elaborar… »
En química y biología, compuesto que se une a sustancias específicas que le son afines, como las proteínas y los ácidos… »
A vessel in which a chemical reaction takes place or an electronic device designed to add reactance to a circuit. »
A type of data storage device which is manufactured with fixed contents. ROM is inherently non-volatile storage, retaining its contents even when… »
Permission that allows a user or program the ability to view information. »
The specific medical individual, usually a radiologist, who looks at and interprets a medical image. »
A device designed to capture data encoded on an object and convert it to a signal that can be input into a… »
One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in nonoverlapping triplets (codons) there… »
A substance used to carry out a laboratory test. Reagents may be used in a chemical reaction to detect, measure, or… »
The lot number of the reagent. »
A data type comprised of fractional numbers. »
Any of the rational or irrational numbers. »
A modified polymerase chain reaction (PCR) technique in which DNA amplification is detected and quantified as the PCR reaction progresses, through the… »
Various XML file formats suitable for disseminating real-time information via subscription on the Internet. »
Procedimiento de urgencia que se usa para reanudar los latidos cardíacos y la respiración de una persona después que uno… »
The National Institutes of Health will consider only two amendments to the initial grant application. Regardless of the number of amendments,… »
A coded value specifying the rationale for an activity or entity. »
The explanation why a particular action was rejected or denied. »
An explanation why a medical device product is exempt from direct part marking. »
The explanation why a summary was necessary for a clinical study. »
The reason that a subject was discontinued from a clinical trial. »
The reason why the problematic device has not been evaluated by the manufacturer. Examples include: device received in a condition which made… »
Terminology used in Individual Case Safety Reports to specify a reason for non-evaluation of a problematic medical product, section F3.3 of FDA… »
A rationale for executing a plan of action. »
The reason the treatment was administered. »
The reason the drug or therapy was temporarily ceased. »
The reason the treatment was not administered. »
A quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin… »
The tosylate salt of rebastinib, an orally bioavailable small-molecule inhibitor of multiple tyrosine kinases with potential antineoplastic activity. Rebastinib binds to and… »
Sustancia en estudio para el tratamiento del cáncer. Pertenece al tipo de medicamentos llamados antibióticos antineoplásicos. »
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antineoplastic antibiotics. … »
A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called antitumor antibiotics and… »
A sulfhydryl-based second-generation matrix metalloproteinase (MMP) inhibitor with potential antineoplastic activity. Rebimastat selectively inhibits several MMPs (MMP 1, 2, 8, 9, and… »
Sorting data into specially chosen classes or bins which differ from those pertaining to the original acquisition. »
Aumento breve y luego descenso de la concentración de APE (antígeno prostático específico) que se presenta en algunos pacientes después de uno… »
Retorno de una enfermedad o de los síntomas y signos de una enfermedad después de un período de mejoría. El término recaída… »
Aumento de la concentración del APE (antígeno prostático específico) en la sangre de los pacientes de cáncer de próstata después del tratamiento… »
A removal or correction of a marketed product that the FDA considers to be in violation of the laws it administers and… »
The date (and time) on which an entity is received. »
A question about whether an individual recieves or received support from their friends. »
Indicates the person or authoritative body who has received something. »
The range between the minimum and maximum cut-off frequencies for a particular receiver, commonly measured in Hertz. »
An electronic device designed to capture an incoming electromagnetic signal and convert it to an audible or visual signal. »
Functions that assign the maximum specificity to each value of sensitivity.The method is used for deciding which clinical data are of importance… »
As part of a cochlear implant, an implanted device designed to receive signal from the external device and then decode the signal… »
A T-lymphocyte that has completed intrathymic development and has exited the thymus. These cells are the youngest peripheral T-lymphocytes and migrate to… »
A substance being studied in the treatment of some types of cancer. Recentin may prevent the growth of new blood vessels that… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. Recentin podría prevenir la formación de vasos sanguíneos nuevos que los… »
Document type (funding opportunity): a PA or RFA not requiring clearance at the NCI Board of Scientific Advisors »
That part of the axis of a flower stalk that bears the floral organs. »
The body of words that a person recognizes and understands when read or heard. »
A test that assesses an individual's understanding of spoken English language. »
A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific effect in… »
Molécula en el interior o la superficie de una célula que se une con una sustancia específica que causa un efecto … »
Proteína que participa en el crecimiento normal de las células. Se encuentra en algunos tipos de células cancerosas, como las de la… »
Proteína que participa en el crecimiento normal de las células. Se encuentra en algunos tipos de células cancerosas, como las de la… »
Any intercellular signaling process in which a transmembrane or intracellular receptor in the responding cell binds to a cognate ligand and initiates… »
Término que describe las células que tienen una proteína que se une a los andrógenos (hormonas masculinas). Las células cancerosas que son… »
Receptor Binding involves a temporary non-covalent, typically highly specific and high affinity, interaction through intermolecular physical forces of attraction and spatial complementarity… »
The study of the regulation of gene expression by nuclear receptors. Includes the mechanisms by which receptors are themselves regulated. … »
Proteína que se encuentra en la superficie de muchos tipos diferentes de células. Se une a una sustancia llamada factor de… »
Proteína que se encuentra en el interior de las células del tejido reproductor femenino, en algunos otros tipos de tejidos y en… »
Describe células que no tienen una proteína a la cual se unirá la hormona estrógeno. Las células cancerosas que son receptoras de… »
Término que describe las células que tienen una proteína receptora que se une a la hormona estrógeno. Las células cancerosas que tienen… »
Proteína que se encuentra en el interior de las células del tejido reproductor femenino, algunos otros tipos de tejido y algunas células… »
Proteína que se encuentra fuera de las células y envía señales hacia las células. Esta señales ayudan a controlar el crecimiento y… »
Proteína que se encuentra en las células de la piel y el ojo que elaboran melanina (un pigmento que da color a… »
Proteína en la superficie de ciertas células que se une a otra proteína que se llama TRAIL, que puede destruir algunas células… »
Proteína de la superficie de ciertas células que se une a otra proteína que se llama TRAIL, que puede destruir células… »
Describe las células que no tienen una proteína a la que se va a unir la hormona progesterona. Las células cancerosas que… »
Describe las células que tienen una proteína a la que se va a unir la hormona progesterona. Las células cancerosas que son… »
Proteína que se encuentra en la superficie de muchos tipos diferentes de células. Se une a una sustancia llamada factor de… »
Proteína que se encuentra en la superficie de algunas células a la cual se une el factor de crecimiento epidérmico y hace… »
Proteína que se encuentra en la superficie de algunos tipos de células y que se une con el factor de crecimiento similar… »
A multicellular process that regulates the extent of response to a stimulus either by modulation of active receptors or inhibition of intracellular… »
A multicellular process that regulates the number of transmembrane receptors, by means of increased internalization or decreased expression of the transmembrane… »
Receptor Genes encode cell surface or cytoplasmic receptor proteins that each bind to specific signaling factors (such as a hormone, antigen, or… »
Proteína celular que se une a una hormona específica. El receptor hormonal puede estar en la superficie de la célula… »
A process by which cells internalize molecules or viruses. Receptors on the plasma membrane of the target cell bind to specific cell… »
Agents that dilate blood vessels, loosen tight junctions and selectively deliver entrapped agents into tumor cells by receptor interaction. »
Encoded by Receptor Serine/Threonine Kinase Genes, Receptor Serine/Threonine Kinases bind to specific signaling factors causing a conformational and functional change in the… »
Receptor Serine/Threonine Kinase Genes encode receptor proteins that each bind to specific signaling factors causing a conformational and functional change in the… »
An intercellular process that involves a cellular receptor binding to a cognate ligand and results in a specific cellular response. »
Refers to the presence or absence of specific receptor molecules on the surface of a cells in a specimen. »
Proteína que se encuentra en las células de la piel y el ojo que elaboran melanina (un pigmento que da color a… »
Proteína en la superficie de ciertas células que se une a otra proteína que se llama TRAIL, que puede destruir algunas células… »
Proteína de la superficie de ciertas células que se une a otra proteína que se llama TRAIL, que puede destruir células… »
A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the… »
Tyrosine kinase receptors (TRKs) are a family of genes encoding neurotrophin receptors that include trkA, trkB, and trkC, which are related to… »
A process that negatively regulates the intracellular catalytic activities that originate with the binding of a tyrosine kinase-associated transmembrane receptor with its… »
A pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. Mitosis-angiogenesis inhibitor (MAI) R1530 inhibits multiple receptor tyrosine kinases involved in angiogenesis,… »
Receptor tyrosine-protein kinase erbB-2 (1255 aa, ~138 kDa) is encoded by the human ERBB2 gene. This protein is involved in cell proliferation,… »
Receptor tyrosine-protein kinase erbB3 (1342 aa, ~148 kDa) is encoded by the human ERBB3 gene. This protein plays a role in protein… »
Receptor tyrosine-protein kinase erbB-4 (1308 aa, ~147 kDa) is encoded by the human ERBB4 gene. This protein is involved in multicellular organismal… »
A family of transcription factors that are activated by signaling mediated by tumor growth factor-beta (TGF-beta) superfamily ligand-receptor interactions. Once activated, R-SMADs… »
Receptor-interacting serine/threonine-protein kinase 1 (671 aa, ~76 kDa) is encoded by the human RIPK1 gene. This protein plays a role in signaling… »
Receptor-interacting serine/threonine-protein kinase 2 (540 aa, ~61 kDa) is encoded by the human RIPK2 gene. This protein is involved in protein phosphorylation,… »
Receptor-interacting serine/threonine-protein kinase 3 (518 aa, ~57 kDa) is encoded by the human RIPK3 gene. This protein plays a role in the… »
Receptor-interacting serine/threonine-protein kinase 4 (832 aa, ~92 kDa) is encoded by the human RIPK4 gene. This protein plays a role in the… »
A family of genes that encode transmembrane receptors, which also have protein tyrosine phosphatase activity. These genes are involved in both the… »
Receptor-type tyrosine-protein phosphatase C (1304 aa, ~147 kDa) is encoded by the human PTPRC gene. This protein plays a role in protein… »
Receptor-type tyrosine-protein phosphatase delta (1912 aa, ~215 kDa) is encoded by the human PTPRD gene. This protein is involved in both dendrite… »
Receptor-type tyrosine-protein phosphatase epsilon (700 aa, ~81 kDa) is encoded by the human PTPRE gene. This protein plays a role in cytokine… »
Receptor-type tyrosine-protein phosphatase epsilon isoform 2 (642 aa, ~75 kDa) is encoded by the human PTPRE gene. This protein is involved in… »
Receptor-type tyrosine-protein phosphatase eta (1337 aa, ~146 kDa) is encoded by the human PTPRJ gene. This protein plays a role in protein… »
Receptor-type tyrosine-protein phosphatase gamma (1445 aa, ~162 kDa) is encoded by the human PTPRG gene. This protein is involved in both protein… »
Receptor-type tyrosine-protein phosphatase kappa (1439 aa, ~162 kDa) is encoded by the human PTPRK gene. This protein is involved in protein dephosphorylation,… »
Receptor-type tyrosine-protein phosphatase R (657 aa, ~74 kDa) is encoded by the human PTPRR gene. This protein is involved in both protein… »
Receptor-type tyrosine-protein phosphatase T (1441 aa, ~162 kDa) is encoded by the human PTPRT gene. This protein is involved in cell-cell adhesion,… »
Reintroduction of previously withdrawn medical intervention in the same patient. »
Cáncer que recidivó (volvió), habitualmente después de un período durante el cual el cáncer no se pudo detectar. El cáncer puede volver… »
Aumento de la concentración del APE (antígeno prostático específico) en la sangre de los pacientes de cáncer de próstata después del tratamiento… »
In medicine, a person who receives blood, cells, tissue, or an organ from another person, such as in a blood transfusion or… »
Concerning each of two or more things, especially those given or done in return. In mathematics, used to denote different kinds of… »
The SI unit of wave number, the spatial analogue of frequency; closely related to the concept of the wave vector. »
A standard way to measure how well a cancer patient responds to treatment. It is based on whether tumors shrink, stay the… »
Método estándar que se usa para medir el modo en que un paciente de cáncer responde al tratamiento. Permite determinar… »
The act of seeing something as familiar. »
En el campo de la genética, describe el ADN, las proteínas, las células o los organismos compuestos por la combinación de material… »
In genetics, describes DNA, proteins, cells, or organisms that are made by combining genetic material from two different sources. Recombinant substances are… »
A recombinant peptide that is chemically identical to or similar to the endogenous 70-kD heat shock protein (HSP70). HSP70 is a… »
Dimeric growth factors of the TGF family with effects on a range of cell types in addition to promoting FSH release in… »
A replication-defective, recombinant adenoviral vector encoding the wild-type human tumor-suppressor protein p53 gene with potential antineoplastic activity. Upon intratumoral administration, rAD-p53 binds… »
A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor… »
A replication-deficient recombinant adenovirus encoding human interferon alpha-2b with potential antineoplastic activity. Upon intravesical administration, recombinant adenovirus-interferon SCH 721015 infects nearby tumor… »
A non-replicating recombinant adenovirus type 5 (Ad5)-vector encoding the gene for interferon alpha-2b (IFN alpha-2b) and the gene transfer enhancement agent Syn… »
A replication-defective adenovirus containing a gene that encodes the human protein L523S with potential antineoplastic activity. Upon administration, recombinant adenovirus-L523S vaccine expresses… »
A substance that has been studied in the treatment of some types of cancer. Recombinant adenovirus-p53 is a weakened adenovirus that carries… »
A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers… »
One of a number of chemotactic cytokines. Alpha chemokines are small polypeptides released by macrophages, endothelial cells, keratinocytes, fibroblasts, and smooth muscle… »
A recombinant form of amphiregulin, a member of the heparin-binding epidermal growth factor (EGF) family. Endogenous amphiregulin is an autocrine growth factor,… »
A 14kD non-glycosylated human derived angiogenesis factor, which has the ability to induce neovascularisation with a unique ribonucleolytic activity. »
Antibodies produced by recombinant DNA techniques. »
An orally available, genetically engineered Salmonella typhimurium strain expressing a truncated form of the human cytokine interleukin-2 (IL-2) gene, with antitumor… »
A recombinant vaccine containing a genetically detoxified adenylate cyclase toxin (CyaA) of Bordetella pertussis coupled, through its catalytic site, to the melanoma… »
Formulated therapeutic analogs of one of a number of endogenous chemotactic polypeptide cytokines. Beta chemokine is synthesized and released by macrophages,… »
A therapeutic analogue of an endogenous, platelet-specific protein that is a member of the alpha chemokine family. Beta thromboglobulin may be… »
A recombinant form of the endogenous Betacellulin, a member of the Epidermal Growth Factor family that is expressed primarily in the pancreas… »
A recombinant, bispecific, single-chain antibody directed against both the T-cell surface-associated costimulatory molecule CD28 and a melanoma-associated proteoglycan (MAPG) with potential antitumor… »
Recombinant therapeutic agents chemically identical to or similar to endogenous nerve growth factors (neurotrophins) that play vital roles in the development of… »
Smaller fragment formed when C5 convertase splits C5 into C5a and C5b. C5a is a 74-amino acid peptide that includes a carboxy-terminal… »
A recombinant therapeutic agent which is chemically identical to or similar to CD40-ligand. CD40-ligand, also known as CD40L/TRAP and CD154, is a… »
A recombinant sialidase fusion protein composed of a sialidase catalytic domain derived from Actinomyces viscosus, a constituent of the normal oral and… »
Formulated therapeutic analogs of one of a number of endogenous small polypeptide cytokines with potential antineoplastic activity. Synthesized by macrophages, endothelial cells,… »
Glycoprotein growth factors produced by monocytes, macrophages, or activated lymphocytes that stimulate the proliferation of bone marrow cells and differentiation of stem… »
A recombinant peptide hormone chemically identical to or similar to human polypeptide hormone corticotropin (adrenocorticotropic hormone; ACTH). Secreted by the anterior pituitary… »
Connective Tissue-Activating Peptide III is a platelet-derived growth factor that stimulates in fibroblasts mitogenesis, extracellular matrix synthesis, glucose metabolism, and plasminogen activator… »
Recombinant form of endogenous delta-chemokine family. »
A cancer vaccine consisting of a truncated recombinant HER2 peptide (dHER2) with potential antineoplastic activity. Upon administration, recombinant dHER2 vaccine may stimulate… »
A recombinant dimeric fusion peptide of the human granulocyte colony-stimulating factor (G-CSF; filgrastim), with immunomodulating and hematopoietic activities. Recombinant dimeric filgrastim fusion… »
Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources usually for the… »
A plasmid DNA encoding human L523S, an RNA-binding protein that belongs to the KOC (K homology domain containing protein overexpressed in cancer)… »
Epithelial neutrophil activating peptide-78. A 78 amino acid member of the CXC family of chemokines, produced and secreted upon stimulation by… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous chemokine eotaxin, a member of the C-C cytokine… »
A recombinant fusion protein composed of the full-length extracellular domain (soluble) of human receptor tyrosine kinase ephrin type-B receptor 4 (sEphB4) and… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous epidermal growth factor (EGF). As a mitogen, EGF… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein erythropoietin (Epo). Epo promotes the differentiation… »
A recombinant agent, which is chemically identical to or similar to the endogenous protein Fas ligand, a protein related to tumor necrosis… »
A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 1 (FGF-1. Because of the mitogenic… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 2 (FGF-2). Reflecting its endogenous… »
A recombinant agent which is chemically identical to or similar to endogenous fibroblast growth factor 3 (FGF-3). FGF-3 is a growth factor… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 4 (FGF-4). Therapeutic FGF-4 induces vascular… »
A recombinant form of the heparin-binding fibroblast growth factor 5 (FGF-5). FGF-5 may function as a growth factor during embryogenesis and… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 6 (FGF-6). Because of the… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 7 (FGF-7). Because it stimulates proliferation… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine Flt3. Flt3 ligand binds to the Flt3… »
A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface… »
A recombinant fowlpox virus vector encoding human B7.1 (CD80 antigen), a T-cell costimulatory molecule. Recombinant Fowlpox-B7.1 may be used as a… »
A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the stimulatory molecule transgene B7-1. Recombinant fowlpox-B7.1 vaccine may enhance antigen… »
A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied… »
A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1,… »
A vaccine adjuvant comprised of a recombinant fowlpox virus vector encoding the protein cytokine GM-CSF. GM-CSF is a protein cytokine secreted by… »
A viral vaccine comprised of a recombinant fowlpox vector construct encoding a modified epitope of the melanoma antigen glycoprotein 100 (gp100), ES-2092M(gp100),… »
A vaccine consisting of a replication-defective recombinant fowlpox virus that encodes for the murine melanoma antigen glycoprotein 100 (mgp100) with potential antineoplastic… »
A recombinant cancer vaccine consisting of a fowlpox virus vector encoding the prostate-specific antigen (PSA). This agent stimulates cytotoxic T-lymphocytes to target… »
A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA). Administration of this agent may stimulate a cytotoxic… »
A cancer vaccine consisting of a recombinant fowlpox virus encoding fragment of human prostate-specific antigen (PSA), PSA:154-163 (155L), and a TRIad of… »
A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied… »
A recombinant fowlpox virus vaccine with potential antineoplastic activity. Binding to the melanoma antigen tyrosinase, recombinant fowlpox-tyrosinase vaccine generates cellular immune responses… »
A pro-inflammatory delta chemokine with potential antineoplastic activity. Fractalkine induces the adhesion and migration of T lymphocytes, monocytes and natural killer… »
A family of synthetic or recombinant C-type chemokines lacking adjacent cysteine residues and act as chemoattractants for lymphocytes. »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous glial cell line-derived neurotrophic factor (GDNF). GDNF is… »
The recombinant form of the endogenous polypeptide hormone Glucagon consisting of 29 amino acids responsible for the release of stored glucose, causing… »
A synthetic luteinizing hormone releasing hormone (LHRH) identical to or similar to the endogenous hormone. Synthesized in and secreted by the hypothalamus,… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein cytokine growth factor granulocyte-macrophage colony stimulating factor… »
A recombinant peptide chemically identical or similar to the endogenous alpha chemokine GRO1 (MGSA) protein. GRO1 protein belongs to a superfamily of… »
Formulated therapeutic proteins that are either isolated from endogenous sources or manufactured in a laboratory. Growth factors bind to specific receptors… »
A haplotype is the order of gene alleles present on a particular chromosome. Thus, a recombinant haplotype exists when a particular… »
Drugs derived from hematopoietic growth factor that promote the development of blood cells. »
Recombinant forms of endogenous Heparin-binding Neurotrophic factors »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein cytokine hepatocyte growth factor (HGF), which is… »
A growth factor of the EGF family that induces growth and differentiation of epithelial, glial and muscle cells in culture. It… »
A therapeutic recombinant analogue of a member of the endogenous CC chemokines with potential antineoplastic activity. Expressed by various lymphoid tissues, endogenous… »
A replication selective, recombinant, E1B and partial E3 gene deleted form of human adenovirus type 5, with potential antineoplastic activity. Upon intratumoral… »
A long-acting recombinant fusion protein incorporating human serum albumin (HSA)-derived and human granulocyte colony stimulating factor (G-CSF)-derived moieties with potential granulopoietic… »
A recombinant, soluble glycosylated form of human angiotensin converting enzyme 2 (rhACE2) with antihypertensive and potential antineoplastic activities. Recombinant human angiotensin converting… »
A recombinant human IgG4 monoclonal antibody directed against transforming growth factor-beta (TGFb) with potential antineoplastic activity. Recombinant human anti-TGF-beta monoclonal antibody specifically… »
An immunoconjugate of recombinant CD4 antigen (rCD4) covalently linked to an immunoglobulin G heavy chain with activity against human immunodeficiency virus… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein hormone human chorionic gonadotropin (HCG). HCG… »
A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k)… »
A recombinant human proteolytic fragment of the C-terminal end of type XVIII collagen. Endostatin induces microvascular endothelial cell apoptosis and inhibits endothelial… »
An immunocytokine consisting of human pro-inflammatory cytokine tumor necrosis factor alpha (TNFalpha) fused to a human single-chain variable fragment (scFv) directed against… »
A recombinant chaperone-peptide complex-based vaccine composed of a complex between heat shock protein hsp110 and the human melanoma-associated antigen gp100, with potential… »
A human recombinant form of the naturally occurring human enzyme hyaluronidase with potential chemoadjuvant activity. Upon local administration, recombinant human hyaluronidase hydrolyzes… »
A recombinant agent which is chemically identical to or similar to the endogenous cytokine interleukin 4 (IL-4) with potential antineoplastic activity. … »
A drug used to increase the number of blood cells, especially platelets, in some cancer patients receiving chemotherapy. Recombinant human interleukin-11 is… »
A drug used to treat some types of cancer. It is a form of interleukin-2, a cytokine made by leukocytes (white blood… »
The recombinant form of endogenous MIP-1 beta chemokine that chemoattracts both neutrophils and monocytes, stimulates macrophages, and stimulates myelopoietic cell growth. … »
A substance that causes blood stem cells (cells from which other types of cells develop) to change into different types of blood… »
A recombinant agent, chemically identical or similar to the endogenous small inducible cytokine A8 (MCP-2). This agent is a member of the… »
A cancer vaccine containing autologous dendritic cells pulsed with a fusion product of an epitope of human tumor-associated epithelial mucin 1 (MUC1)… »
A vaccine used to prevent cervical cancer caused by human papillomavirus (HPV) types 16 and 18. Recombinant human papillomavirus bivalent vaccine is… »
A vaccine used to prevent anal, cervical, vulvar, and vaginal cancer caused by human papillomavirus (HPV) types 16, 18, 31, 33, 45,… »
A vaccine used to prevent anal, cervical, vulvar, and vaginal cancer caused by human papillomavirus (HPV) types 16 and 18 and genital… »
A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, recombinant human serum amyloid… »
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell… »
A humoral factor that controls blood platelet production through stimulation of megakaryocyte populations. Bone marrow megakaryocytes increase in both size and number… »
A recombinant form of human I-309, an inflammatory CXC cytokine secreted by activated T lymphocytes that appears to be an inducer of… »
Recombinant form of endogenous Insulin-like Growth Factor II exhibiting mitogenic activity. »
Recombinant inbred (RI) strains are derived by systematic inbreeding from the cross of two pre-existing progenitor strains. (from JAX Strain Information) … »
Recombinant therapeutic agents chemically identical to or similar to endogenous glycoproteins which inhibit pituitary production of follicle-stimulating hormone (FSH). Inhibin has… »
A recombinant therapeutic agent which is chemically identical to or similar to an endogenous glycoprotein which inhibits pituitary production of follicle-stimulating hormone… »
A recombinant therapeutic agent which is chemically identical to or similar to an endogenous glycoprotein which inhibits pituitary production of follicle-stimulating hormone… »
A recombinant human antiapoptotic growth factor. Recombinant insulin-like growth factor (IGF) binds to and activates the insulin and IGF receptors; activation… »
One of a group of recombinant therapeutic glycoprotein cytokines with antiviral, anti-proliferative, and immunomodulating activities. Interferons bind to specific cell-surface receptors, leading… »
A class of naturally-isolated or recombinant therapeutic peptides used as antiviral and anti-tumor agents. Alpha interferons are cytokines produced by nucleated… »
The non-glycosylated recombinant interferon alpha, subtype 1b, with immunostimulatory and antineoplastic activities. Alpha interferon-1b binds to specific cell-surface receptors, resulting in the… »
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface… »
A drug used to treat AIDS-related Kaposi sarcoma in certain patients, hairy cell leukemia, and melanoma that has been removed by… »
A proprietary recombinant protein highly resembling human interferon alpha 2b (IFN-a2b), with potential anti-tumor, anti-inflammatory, immunomodulating and antiviral activities. Upon injection, recombinant… »
A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and… »
A recombinant agent, chemically identical or similar to the endogenous small inducible cytokine B10 (IP-10). Interferon-alpha inducible protein 10 is secreted from… »
Formulated therapeutic analogs of one of a number of endogenous cytokine interleukins. Produced by T cells, macrophages, and other cells, interleukins… »
A recombinant cytokine chemically identical to or similar to interleukin-10 (IL-10) secreted by certain leukocytes with immunomodulatory activities. IL-10 is an anti-inflammatory… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-1 (IL-1). Produced mainly by monocytes, endogenous… »
Any of the recombinant form of the naturally occurring Interleukin-1 Receptor Antagonist that blocks the biological activity of Interleukin-1 by binding to… »
A recombinant agent which is chemically identical to or similar to the endogenous protein cytokine interleukin-1 (IL-1). The IL-1 precursor is produced… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine interleukin 1 (IL-1)-beta. Produced by monocytes… »
A recombinant form of the endogenous heterodimeric cytokine interleukin-12 with potential antineoplastic activity. Recombinant interleukin-12 binds to and activates its cell-surface… »
The recombinant analogue of an endogenous cytokine interleukin 13 with potential antineoplastic activity. Produced by lymphocytes and exhibiting a variety of functions,… »
A recombinant peptide, which is chemically identical or similar to the endogenous cytokine interleukin-14 (IL-14). The cytokine inhibits immunoglobulin secretion and selectively… »
A recombinant agent that is chemically identical or similar to the endogenous cytokine interleukin-15 (IL-15) with immunomodulating activity. IL-15, secreted by mononuclear… »
A recombinant chemokine of human lymphotactin which is produced by activated progenitor T cells and characterized by specific chemotactic activity for… »
A recombinant agent, which is chemically identical or similar to the endogenous cytokine interleukin-17 (IL-17). IL-17 is produced by cytotoxic T cells… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-18 (IL-18). Produced primarily by macrophages, IL-18… »
Any recombinant analog of endogenous interleukin-2 (IL-2), a cytokine involved in intercellular communication related to cell differentiation, proliferation, inflammation, hematopoiesis, neuronal functions,… »
A recombinant form of interleukin-3, a cytokine produced by activated T-cells and mast cells involved in intercellular communication, hematopoiesis, and inflammation. IL-3… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-5 (IL-5). Produced by T cells,… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-6 (IL-6) with antiapoptotic, proinflammatory, antiinflammatory, proproliferative… »
A recombinant protein which is chemically identical to or similar to endogenous interleukin-7 (IL-7) with hematopoietic and immunopotentiating properties. Produced by bone… »
A member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-9 (IL-9). Produced by CD4+ lymphocytes, IL-9… »
A recombinant counterpart of tumor-associated KSA antigen (Ep-CAM), a type-I transmembrane glycoprotein cellular adhesion molecule with a molecular mass of 40 kDa,… »
affects many systems, including hematopoietic, embryonic, bone, hepatic, neuronal, and fat tissues. »
A cocktail preparation of synthetic interleukin (IL) -1, IL-2, IL-6 , tumor necrosis factor (TNF)-alpha, interferon gamma and other cytokines that are… »
A formulated therapeutic analog of the endogenous lymphokine leukoregulin with potential antineoplastic activity. Leukoregulin displays direct and indirect cytotoxicity through tumor… »
A hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their eggs and to… »
A type of cytokine produced by lymphocytes for therapeutic use involving cellular immunity. »
A recombinant chemokine of human lymphotactin which is produced by activated progenitor T cells and characterized by specific chemotactic activity for… »
Lymphotoxin is a cytokine that orchestrates lymphoid neogenesis and is present on the surface of activated T-, B-, and LAK cells as… »
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous protein cytokine macrophage colony-stimulating factor (M-CSF). Synthesized endogenously… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous macrophage inflammatory protein-1, a member of the CC chemokine… »
A therapeutic analogue of the endogenous CXC cytokine macrophage inflammatory protein-2 alpha. Macrophage inflammatory protein-2 alpha attracts and activates neutrophils and may… »
A formulated therapeutic analog of the endogenous pro-inflammatory alpha (CXC) chemokine macrophage inflammatory protein-2 beta that stimulates neutrophil chemotaxis and induces neutrophil… »
A recombinant tumor-specific melanoma antigen. Vaccination with recombinant MAGE-3.1 antigen may induce a host immune response against MAGE-expressing cells, resulting in antitumoral… »
A recombinant form of neurotrophic growth factor that regulates the development and maintenance of motor neurons expressing trk B receptor tyrosine kinase,… »
A recombinant form of a human macrophage inflammatory protein-1 alpha (MIP1-alpha) with a substitution of aspartate to alanine at position 26, with… »
A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the 5T4 fetal oncoprotein (MVA-h5T4). Vaccination with recombinant… »
A recombinant therapeutic agent which is chemically identical to or similar to endogenous human monocyte chemoattractant protein-1, a member of the CC… »
An 85-amino acid recombinant peptide derived from protein c2 of the hemophagocytic hookworm Ancylostoma caninum (a common canine parasite) with anticoagulant… »
NERVE GROWTH FACTOR is the first of a series of neurotrophic factors that were found to influence the growth and differentiation of… »
Recombinant forms of endogenous neuropoietic cytokines. »
Recombinant form of endogenous neurotrophic factors, a family of polypeptide growth factors produced by peripheral target tissues as well as the nervous… »
family of polypeptide growth factors produced by peripheral target tissues as well as the nervous system, which are critical to neuronal growth,… »
A genetically engineered synthetic protein, Recombinant NY-ESO-1 Protein (Cancer-Testis Tumor Antigen Family) elicits strong humoral and cellular immune responses to NY-ESO-1-expressing cancers… »
A recombinant, live attenuated, nonpathogenic oncolytic virus containing the oral poliovirus Sabin type 1 in which the internal ribosomal entry site (IRES)… »
A recombinant 26.0 kDa protein, containing 227 amino acid residues, a member of the cytokine family and growth and differentiation factor that… »
A recombinant agent, which is chemically identical to or similar to the endogenous protein Fas ligand OX40, a member of the tumor… »
A synthetic cyclic peptide form of the naturally occurring posterior pituitary hormone oxytocin. Oxytocin binds to oxytocin receptors in the uterine myometrium,… »
A recombinant therapeutic agent that is identical or similar to an 84-amino-acid polypeptide produced by the parathyroid gland which functions to maintain… »
calcium-regulating hormone with endocrine, paracrine, and autocrine actions in bone; can cause hypercalcemia. »
A recombinant form of the endogenous chemokine platelet factor 4 with potential antiangiogenesis and antineoplastic activities. As a heparin-binding tetramer, recombinant platelet… »
Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif of eight… »
A recombinant form of the heparin-binding cytokine pleiotrophin. Developmentally regulated, pleiotrophin functions as a growth factor during embryogenesis and the neonatal… »
A recombinant form of the human PRAME (Preferentially Expressed Antigen of Melanoma) protein combined with the AS15 adjuvant, with potential immunostimulatory and… »
Proteins produced by genes or recombinant DNA that has been artificially engineered and inserted into a heterologous host. Recombinant proteins are used… »
In vivo synthesis of recombinant proteins through recombinant DNA techniques, followed by purification. »
A recombinant form of the endogenous polypeptide hormone that exerts immunomodulatory effects primarily on mononuclear cells. Prothymosin alpha stimulates the production… »
A member of the IL-8 superfamily of cytokines and released from platelets and activated T-cells, RANTES is a selective chemoattractant for eosinophils,… »
A whole, heat-killed, recombinant Saccharomyces cerevisiae yeast-based vaccine genetically altered to express the carcinoembryonic antigen (CEA) peptide 610D with potential immunostimulating and… »
A recombinant human soluble CD4 with antiviral activity. Recombinant human soluble CD4 has the amino terminus but not the T-cell binding domain… »