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Medroxyprogesterone
Pronunciation
Definition 1
A hormonal anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called progestins. (NCI Dictionary)
Definition 2
A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. (NCI Thesaurus)
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