Mefenamic Acid

An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. (NCI Thesaurus)

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MEF2D wt Allele

Human MEF2D wild-type allele is located within 1q12-q23 and is approximately 37 kb in length. This allele, which encodes myocyte-specific enhancer factor…

MEF2D Gene

This gene plays a role in muscle and neuronal development.

MEF2C wt Allele

Human MEF2C wild-type allele is located in the vicinity of 5q14 and is approximately 186 kb in length. This allele, which encodes…

MEF2C Gene

This gene plays a role in muscular and vascular development.

MEF2B wt Allele

Human MEF2B wild-type allele is located in the vicinity of 19p13.11 and is approximately 47 kb in length. This allele, which encodes…

MEF2B Gene

This gene is involved in transcriptional regulation.