| Health / Medical Topics |
Mespirenone
A spironolactone derivative and aldosterone antagonist with diuretic activity. Mespirenone, after in vivo metabolization, inhibits aldosterone synthase (steroid 18-hydroxylase), thereby preventing the synthesis of aldosterone in addition to the synthesis of other mineralocorticoids. The blockade of aldosterone synthesis results in increased sodium and water excretion while reducing potassium excretion within the kidney. Mespirenone has a short half-life and is metabolized completely into active metabolites. (NCI Thesaurus)
YOU MAY ALSO LIKE
The peritoneal fold that covers and attaches the ovary to the broad ligament.
There are two mesothoriums produced in thorium decay. Mesothorium I is an isotope of radium; mesothorium II is an isotope of…
A simple layer of cells, derived from the mesoderm that lines the coelom or body cavity of the embryo. In the adult,…
A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities. Upon…
A benign (not cancer) or malignant (cancer) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the…
A preparation of peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding a T cell chimeric antigen receptor (CAR) specific for…
