| Library / English Dictionary |
METABOLITE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any substance involved in metabolism (either as a product of metabolism or as necessary for metabolism)
Classified under:
Hypernyms ("metabolite" is a kind of...):
substance (a particular kind or species of matter with uniform properties)
Context examples:
This metabolite is a competitive inhibitor of DNA synthesis.
(Arabinofuranosylcytosine Triphosphate, NCI Thesaurus)
Metabolite Interaction involves a biophysical interaction with a biological metabolite.
(Metabolite Interaction, NCI Thesaurus)
Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil.
(Mycophenolic Acid, NCI Thesaurus)
The nuclear receptor CAR is activated by many different exogenous compounds, including acetaminophen, inducing expression of three cytochrome P450 enzymes that transform acetaminophen into NAPQI, a reactive and toxic metabolite.
(Acetaminophen Pathway, NCI Thesaurus/BIOCARTA)
Spermine is a metabolite – a substance involved in metabolism – that plays an important role in all cells and is even essential for the growth of some bacteria.
(Baby’s sex affects mother’s metabolism and may influence risk of pregnancy-related complications, University of Cambridge)
The parent drug and metabolites are mainly excreted in the urine and its half-life is about 1.5 hours.
(Nateglinide, NCI Thesaurus)
The team analyzed metabolites in some of the infant’s stool samples.
(Infant gut microbes linked to allergy, asthma risk, NIH)
A main metabolite of the selective estrogen receptor modulator tamoxifen with anti-estrogen activity.
(N-Desmethyltamoxifen, NCI Thesaurus)
Mycotoxins are toxic, secondary metabolites of low molecular weight produced by naturally occurring fungi.
(Mycotoxin, NCI Thesaurus)
A metabolite of AMITRYPTYLINE that is also used as an antidepressive agent.
(Nortriptyline Hydrochloride, NLM, Medical Subject Headings)
