| Health / Medical Topics |
Methyldopate Hydrochloride
The hydrochloride salt form of methyldopa, a phenylalanine derivate and aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. (NCI Thesaurus)
YOU MAY ALSO LIKE
A phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the…
Methylcytosine dioxygenase TET2 (2002 aa, ~224 kDa) is encoded by the human TET2 gene. This protein is involved in methylcytosine oxidation. …
Methylcytosine dioxygenase TET1 (2136 aa, ~235 kDa) is encoded by the human TET1 gene. This protein is involved in the mediation of…
The methyl ether of cellulose with laxative activity. Methylcellulose is not absorbed by the intestines and attracts large amounts of water into…
A DNA sequencing technique that can differentiate cytosine from 5-methylcytosine in a DNA sample. It combines bisulfite treatment with next generation sequencing…
A sequence in DNA that can be recognized by a specific methylase enzyme and that contains the specific base target for methyl…
