Health / Medical Topics

    MHC Class II Protein

    Definition 1

    MHC Class-II Proteins are non-covalently linked polymorphic alpha/beta transmembrane glycoproteins. The immunological function of MHC Class-II proteins is to bind and present antigenic peptides on the surfaces of cells for recognition by the antigen-specific T cell receptors of lymphocytes. These proteins plays an important role in the mediation of immune response. (NCI Thesaurus)

    Definition 2

    One of a group of proteins found on the surface of white blood cells and other cells that play an important part in the body's immune response to foreign substances. These antigens vary from person to person, and human leukocyte antigen tests are done before organ transplantation to find out if tissues match between a donor and a recipient. (NCI Dictionary)




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